Etrovis SP Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual weight gain or swelling of ankles
- Severe skin rash or blisters
- Persistent nausea or vomiting
If experiencing severe symptoms, call emergency services immediately.
What is xircox sp tablet used for?
This medicine is a combination of Etoricoxib 60 mg and Serratiopeptidase 10 mg used to relieve pain and inflammation in conditions like arthritis, gout, and post-surgical swelling. It works by blocking pain-causing chemicals and reducing swelling. Take it once daily with food, and avoid alcohol. Do not use without a prescription.
- Generic Name: Etoricoxib (60mg) + Serratiopeptidase (10mg)
- Manufacturer: HBC Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 xircox sp tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरिकॉक्सिब 60 मिलीग्राम और सेरेशियोपेप्टिडेज़ 10 मिलीग्राम का संयोजन है। इसका उपयोग गठिया, गाउट, सर्जरी के बाद दर्द और सूजन, और चोट के बाद होने वाले दर्द और सूजन के इलाज के लिए किया जाता है। यह दर्द और सूजन को कम करने में मदद करती है। इसे भोजन के साथ लें और शराब से बचें। बिना डॉक्टर की सलाह के इसका सेवन न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पेट दर्द, मतली, अपच, दस्त और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति, हृदयाघात और स्ट्रोक शामिल हो सकते हैं। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, त्वचा या आंखों का पीलापन, पेशाब में कमी, या चेहरे, होंठ या गले में सूजन दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक या अवधि से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको पेट के अल्सर, गुर्दे या यकृत की बीमारी, हृदय की समस्या, या उच्च रक्तचाप है तो अपने डॉक्टर को बताएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले अपने डॉक्टर से सलाह लें। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं या मशीनरी न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 xircox sp tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Provides rapid relief from pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Post-surgical pain and swelling","description":"Helps manage pain and reduce swelling after surgical procedures.","evidence":"Moderate"},{"condition":"Post-traumatic pain","description":"Used for pain and swelling following injuries such as sprains and fractures.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and acute gouty arthritis.
Also treats: Post-surgical pain and swelling, Post-traumatic pain and swelling, Ankylosing spondylitis, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Etoricoxib (60mg) + Serratiopeptidase (10mg) |
| Brand Name | xircox sp tablet |
| Manufacturer | HBC Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Etoricoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is induced during inflammation and is responsible for producing prostaglandins that cause pain, swelling, and fever. By blocking COX-2, etoricoxib reduces these symptoms without significantly affecting COX-1, which helps protect the stomach lining. Serratiopeptidase is a proteolytic enzyme that breaks down inflammatory proteins and fibrin, thereby reducing swelling and edema. It also may improve tissue repair and reduce mucus viscosity. Together, they provide anti-inflammatory, analgesic, and anti-edema effects.
Mechanism Steps
💡 How to Take xircox sp tablet
Strength: Tablet containing Etoricoxib 60 mg and Serratiopeptidase 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably with food. The dose may be adjusted by your doctor based on the condition being treated, your age, kidney and liver function, and other medications you are taking. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use with caution and monitor closely. Dose adjustment may be necessary based on kidney function. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually needed. However, this medicine is not recommended in patients with severe kidney impairment (creatinine clearance less than 30 mL/min). Consult your doctor for dose adjustment. |
| Hepatic Impairment | In patients with mild liver impairment (Child-Pugh score 5-6), no dose adjustment is needed. In patients with moderate liver impairment (Child-Pugh score 7-9), the dose should not exceed 60 mg once daily. This medicine is not recommended in patients with severe liver impairment (Child-Pugh score greater than 9). Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose of etoricoxib is 90 mg. For this combination, the maximum daily dose is one tablet (60 mg etoricoxib + 10 mg serratiopeptidase) unless otherwise prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of xircox sp tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antihypertensives | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- ACE inhibitors
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Antihypertensives
- Cyclosporine
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding, ulcers, and liver problems. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to etoricoxib, serratiopeptidase, or any component of the formulation","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe liver impairment","Severe kidney impairment","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Pregnancy (especially third trimester)","Breastfeeding","Children under 16 years of age"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with a history of gastrointestinal bleeding or ulcers.","Monitor blood pressure regularly as it can increase.","Use with caution in patients with kidney or liver disease.","May increase risk of cardiovascular events; use with caution in patients with heart disease.","Do not use for more than the recommended duration without medical advice.","Avoid alcohol consumption.","Do not drive or operate machinery if you experience dizziness.","Inform your doctor if you are taking any other medications, especially blood thinners.","Stop the medicine and seek medical help if you experience signs of an allergic reaction."]
🤱 Lactation Safety
Etoricoxib is excreted in breast milk and is not recommended during breastfeeding. Serratiopeptidase safety during breastfeeding is not established. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this medicine may cause severe abdominal pain, nausea, vomiting, drowsiness, and gastrointestinal bleeding. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or high blood pressure. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution and monitor closely. Dose adjustment may be necessary based on kidney function. Avoid long-term use unless absolutely necessary.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are trying to conceive, consult your doctor for alternative treatments. Etoricoxib may interfere with ovulation and is contraindicated in the third trimester. Serratiopeptidase safety in pregnancy is not established.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to manage pain and swelling. Take it exactly as directed by your surgeon. Inform your surgeon about all other medications you are taking. Do not use it for more than the recommended duration without medical advice.
🦷 Dental Procedures
If you are scheduled for dental surgery or procedures, inform your dentist that you are taking this medicine. It may increase the risk of bleeding. Your dentist may advise you to stop it temporarily before the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have joint pain, consult a physiotherapist for safe exercises. Do not overexert yourself, as this may worsen inflammation.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving or operating heavy machinery. It is generally safe to continue desk work, but take breaks to move around if you have joint pain. Inform your employer if you need any accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as black stools, vomiting blood, severe abdominal pain, chest pain, difficulty breathing, yellowing of skin or eyes, decreased urine output, or severe skin rash. Do not stop taking this medicine without consulting your doctor, as your condition may worsen.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney problems, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of blood pressure, kidney and liver function, and complete blood count is recommended. Use the lowest effective dose for the shortest duration possible. Consult your doctor if you need to use it for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain in some patients with osteoarthritis.
Evidence: ModerateReduces stress on weight-bearing joints and improves symptoms.
Evidence: Well-establishedMay provide localized pain relief with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking your dose at the same time each day as close as possible. Check customs regulations for carrying prescription medicines. Always carry enough supply for your trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 1 to 2 hours after taking it. However, the full anti-inflammatory effect may take a few days of regular use.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and ulcers.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine can interact with several other drugs, including blood thinners, blood pressure medicines, and antidepressants. Always inform your doctor about all medications you are taking.
A: Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on the appropriate duration of treatment.
🤔 Common Patient Concerns
🔄 Substitutes for xircox sp tablet
View AllAlternative brands with exact same active ingredient:
-
etovix sp 60mg/10mg tabletCuber Lifesciences ₹85.00 25.1% CHEAPER
-
Need-SP TabletGlorious Biotech ₹89.06 21.5% CHEAPER
-
ethicoxia s 60mg/10mg tabletEthics Health Care Pvt Ltd ₹91.36 19.5% CHEAPER
-
etrogod sp 60mg/10mg tabletGodase Healthcare ₹99.38 12.4% CHEAPER
-
cox sp 60mg/10mg tabletElite Pharma Pvt Ltd ₹120.94 6.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for inflammatory pain and swelling. It is not effective for all types of pain, such as neuropathic pain or headache. - Myth: It is safe to take this medicine for a long time without monitoring.
Fact: Long-term use can increase the risk of stomach bleeding, kidney problems, and heart issues. Regular monitoring by a doctor is essential. - Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce the risk of stomach upset and ulcers. - Myth: This medicine is safe during pregnancy.
Fact: It is not recommended during pregnancy, especially in the third trimester, as it may harm the baby.
🔄 Alternative Options
Generic Alternatives
- Etoricoxib 60 mg + Serratiopeptidase 10 mg tablet (generic)
Brand Alternatives
- Etrovis SP Tablet