aztra 40mg tablet - Azilsartan medoxomil (40mg) medicine

Abel 40 Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 HBC Lifesciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is not recommended during pregnancy. It can cause harm to the developing baby, especially in the second and third trimesters. If you become pregnant while taking this medicine, contact your doctor immediately. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Swelling of the face, lips, throat, or tongue
  • Difficulty breathing or swallowing
  • Decreased urine output or swelling in the legs
  • Irregular heartbeat or palpitations
  • Severe headache with visual changes
  • Muscle pain with dark urine

If experiencing severe symptoms, call emergency services immediately.

What is aztra 40mg tablet used for?

This medicine is an angiotensin II receptor blocker (ARB) used to treat high blood pressure in adults. It works by relaxing blood vessels, allowing blood to flow more easily and lowering blood pressure. It is taken once daily, with or without food, and should not be used during pregnancy.

  • Generic Name: Azilsartan medoxomil
  • Manufacturer: HBC Lifesciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 aztra 40mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करने में मदद करती है। इसे आमतौर पर दिन में एक बार लिया जाता है, खाने के साथ या बिना। यह दवा रक्तचाप को नियंत्रित रखने में मदद करती है और स्ट्रोक, दिल के दौरे और किडनी की समस्याओं के जोखिम को कम करती है।

साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे चक्कर आना, सिरदर्द, थकान और हल्का पेट खराब होना। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। अगर आपको चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या पेशाब कम आना जैसी गंभीर समस्या हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। अगर आपको अच्छा महसूस हो रहा है तो भी दवा लेना जारी रखें, क्योंकि उच्च रक्तचाप के अक्सर कोई लक्षण नहीं होते। इस दवा के साथ शराब न पिएं। अगर आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो तुरंत डॉक्टर को बताएं। नियमित रूप से रक्तचाप और किडनी की जांच कराते रहें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 aztra 40mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, helping to reduce the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

📋 Drug Information

Generic Name(s)Azilsartan medoxomil
Brand NameAbel 40 Tablet
ManufacturerHBC Lifesciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin receptor blockers(ARB)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed. Protect from moisture and light.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly at home and keep a record to share with your doctor.
3
Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure.
4
Do not stop taking this medicine without consulting your doctor, even if you feel well.
5
Inform your doctor if you experience persistent dizziness, tiredness, or decreased urine output.
6
Tell your doctor about all other medicines you are taking, especially pain relievers and potassium supplements.
7
If you are planning pregnancy or become pregnant, contact your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter oral administration, azilsartan medoxomil is rapidly absorbed and converted to its active form, azilsartan. The absolute bioavailability of azilsartan is approximately 60%. Food does not significantly affect the absorption of this medicine.
DistributionAzilsartan is highly bound to plasma proteins, primarily albumin. The volume of distribution is approximately 16 liters. It does not appear to distribute extensively into red blood cells.
Protein BindingGreater than 99% bound to plasma proteins, mainly albumin.
MetabolismAzilsartan medoxomil is a prodrug that is hydrolyzed to the active metabolite, azilsartan, during absorption. Azilsartan is further metabolized in the liver, primarily by the enzyme CYP2C9, to two inactive metabolites.
Half-LifeThe elimination half-life of azilsartan is approximately 11 hours.
ExcretionFollowing oral administration, about 55% of the dose is excreted in the feces and about 42% in the urine, mainly as metabolites. Less than 2% is excreted unchanged in the urine.
BioavailabilityThe absolute bioavailability of azilsartan is approximately 60%.
Onset of ActionThe blood pressure-lowering effect begins within 1 to 2 weeks of starting treatment, with the full effect achieved after about 4 weeks.
Peak Plasma TimeThe peak plasma concentration of azilsartan is reached approximately 1.5 to 3 hours after oral administration.
Duration of ActionThe blood pressure-lowering effect lasts for about 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by selectively blocking the angiotensin II type 1 (AT1) receptor. Angiotensin II is a hormone that causes blood vessels to narrow and also stimulates the release of aldosterone, a hormone that makes the body retain salt and water. By blocking the AT1 receptor, this medicine prevents angiotensin II from exerting its effects, leading to relaxation and widening of blood vessels, increased excretion of salt and water, and a reduction in blood pressure. This mechanism also reduces the workload on the heart and helps protect the kidneys.

Mechanism Steps

1
Blockade of AT1 receptors: This medicine binds to and blocks the angiotensin II type 1 receptors located on blood vessels and other tissues.
2
Prevention of vasoconstriction: By blocking these receptors, angiotensin II cannot cause blood vessels to narrow, so they remain relaxed and widened.
3
Reduced aldosterone release: Blockade of AT1 receptors in the adrenal glands reduces the release of aldosterone, leading to less salt and water retention.
4
Lower blood pressure: The combined effect of vasodilation and reduced fluid retention leads to a decrease in blood pressure.

💡 How to Take aztra 40mg tablet

Strength: 40 mg immediate-release tablet.

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day to help you remember.
4Do not crush, chew, or break the tablet unless your doctor tells you to.
5If you have trouble swallowing the tablet, ask your doctor or pharmacist for advice.

Dosage Information

Adult DosageThe usual starting dose of this medicine for high blood pressure in adults is 40 mg once daily. Your doctor may increase the dose to 80 mg once daily if needed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Take this medicine at the same time each day, with or without food.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo dose adjustment is required for elderly patients based on age alone. However, elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely.
Renal ImpairmentNo dose adjustment is required for patients with mild to moderate kidney impairment. In patients with severe kidney impairment or those on dialysis, use with caution and monitor kidney function and potassium levels closely.
Hepatic ImpairmentNo dose adjustment is required for patients with mild to moderate liver impairment. There is limited experience in patients with severe liver impairment; use with caution.
Maximum Daily Dose80 mg once daily.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect the absorption of this medicine.
High-potassium foods
No specific restriction, but monitor if kidney problems
This medicine can increase potassium levels.
Salt substitutes
Use with caution
Many contain potassium, which can increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of aztra 40mg tablet

✅ Common Side Effects

Dizziness (Common (1-10%))
Get up slowly from sitting or lying position. Avoid driving if you feel dizzy. Consult your doctor if dizziness persists.
Headache (Common (1-10%))
Usually resolves on its own. Rest and stay hydrated. Consult your doctor if headache is severe or persistent.
Tiredness (Common (1-10%))
Ensure adequate rest. If tiredness interferes with daily activities, consult your doctor.
Mild stomach upset (Common (1-10%))
Take the medicine with food if it upsets your stomach. Consult your doctor if symptoms continue.

🚨 Serious Side Effects

Severe hypotension (very low blood pressure) (Uncommon (<1%))
Seek immediate medical attention if you feel faint, have blurred vision, or experience a sudden drop in blood pressure.
Kidney problems (Uncommon (<1%))
Contact your doctor if you notice decreased urine output, swelling in your legs, or unusual fatigue.
Allergic reactions (Rare (<0.1%))
Seek emergency help if you experience swelling of the face, lips, throat, or tongue, difficulty breathing, or a severe rash.

⚠️ Rare Side Effects

Angioedema
Seek immediate medical attention if you notice swelling of the face, lips, or throat, or difficulty breathing.
Rhabdomyolysis
Report muscle pain, tenderness, or weakness, especially if accompanied by dark urine, to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Aliskiren Major
Potassium supplements Major
Lithium Major
NSAIDs Moderate
Diuretics Moderate

🚨 Major Interactions

  • Aliskiren
  • Potassium supplements or potassium-sparing diuretics
  • Lithium

⚡ Moderate Interactions

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Diuretics

🍷 Alcohol Interaction

Alcohol may increase the blood pressure-lowering effect of this medicine and can cause dizziness, lightheadedness, or fainting. It is best to avoid alcohol or limit its intake while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to azilsartan medoxomil or any component of the tablet","Pregnancy","Concomitant use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["This medicine can cause low blood pressure, especially in patients who are volume-depleted or taking diuretics. Correct volume depletion before starting treatment.","Use with caution in patients with kidney artery narrowing (renal artery stenosis).","Monitor potassium levels regularly, especially in patients with kidney disease or those taking potassium supplements.","This medicine is not recommended during pregnancy. Women of childbearing age should use effective contraception.","Do not use this medicine in children without specialist advice."]

🤱 Lactation Safety

It is not known whether azilsartan is excreted in human breast milk. Because of the potential for adverse effects in a breastfed infant, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, and very low blood pressure. Treatment is supportive and symptomatic. Hemodialysis is not likely to be effective in removing azilsartan from the body.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor first. Keep taking it even if you feel well, because high blood pressure often has no symptoms. Avoid alcohol while taking this medicine, as it can increase dizziness and lower your blood pressure too much. Stand up slowly from a sitting or lying position to avoid feeling dizzy. Tell your doctor about all other medicines, supplements, and herbal products you are taking, especially potassium supplements, salt substitutes, and pain relievers. If you are pregnant or planning to become pregnant, inform your doctor immediately, as this medicine is not safe during pregnancy. Regular monitoring of blood pressure and kidney function is important while you are on this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Regular monitoring of kidney function and potassium levels is also recommended.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dizziness or low blood pressure during dental procedures. Your dentist may take precautions, such as monitoring your blood pressure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Follow a balanced diet rich in fruits, vegetables, and whole grains.
😴
Reduce salt intake to help lower blood pressure.
💧
Engage in regular physical activity, such as brisk walking or swimming.
🧘
Limit alcohol consumption and avoid smoking.
🌞
Manage stress through relaxation techniques like deep breathing or meditation.
🚭
Get adequate sleep to support overall health.

🏋️ Exercise Considerations

Regular exercise is beneficial for blood pressure control, but avoid sudden strenuous activities if you are not used to them. Stay hydrated, and if you feel dizzy or faint during exercise, stop and rest. Consult your doctor before starting a new exercise program.

🥗 Diet Recommendations

Include potassium-rich foods like bananas, oranges, and spinach, but monitor if you have kidney problems.
Reduce sodium intake by avoiding processed and packaged foods.
Eat a variety of fruits, vegetables, and whole grains.
Choose lean proteins and healthy fats.
Limit sugary drinks and foods high in added sugars.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people, especially when standing up quickly. If you experience dizziness, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal daily activities while taking this medicine.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to change your treatment, they will advise you on how to stop safely. Suddenly stopping this medicine can cause your blood pressure to rise again.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for controlling high blood pressure. Regular monitoring of blood pressure, kidney function, and potassium levels is recommended. In some patients, long-term use may be associated with mild reductions in kidney function, especially if other risk factors are present. Your doctor will periodically assess the benefits and risks of continuing treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, weight loss, and stress reduction can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive medicines

Other classes of blood pressure medicines, such as ACE inhibitors, calcium channel blockers, or diuretics, may be used alone or in combination.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established from the available information. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry your medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. If crossing time zones, continue taking your medicine at the same interval as prescribed, but consult your doctor for specific advice. Store at room temperature and protect from moisture. Check customs regulations for carrying prescription medicines to your destination.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with newly diagnosed high blood pressure
He was prescribed this medicine 40 mg once daily. After two weeks, his blood pressure started coming down. He experienced mild dizziness initially, which went away after a few days. He now monitors his blood pressure at home and takes the medicine at the same time every morning.
💡 Lesson: Consistent daily dosing and regular monitoring help achieve good blood pressure control. Mild side effects often improve with time.
👤 A 60-year-old woman with diabetes and hypertension
She was started on this medicine along with her diabetes medicines. Her doctor monitored her kidney function and potassium levels regularly. She was advised to avoid salt substitutes and NSAIDs. Her blood pressure remained well-controlled without significant side effects.
💡 Lesson: Regular monitoring of kidney function and potassium is important, especially in patients with diabetes. Avoiding certain foods and medicines helps prevent complications.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1 to 2 weeks, with the full effect after about 4 weeks.

Q: Can I take this medicine with food?

A: Yes, this medicine can be taken with or without food.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: No, this medicine is not safe during pregnancy. It can harm the developing baby. Inform your doctor immediately if you become pregnant.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping the medicine can cause your blood pressure to rise again.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for aztra 40mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure high blood pressure permanently.
    Fact: This medicine controls high blood pressure but does not cure it. You may need to take it long-term.
  • Myth: You can stop taking this medicine once your blood pressure is normal.
    Fact: High blood pressure often has no symptoms. Stopping the medicine can cause your blood pressure to rise again. Always consult your doctor before stopping.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is not safe during pregnancy and can harm the developing baby. Inform your doctor immediately if you become pregnant.

🔄 Alternative Options

Generic Alternatives

  • Azilsartan medoxomil

Brand Alternatives

  • Abel 40 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Azilsartan medoxomil","class":"ARB","usual_dose":"40-80 mg once daily","common_side_effects":"Dizziness, headache, tiredness"},{"medicine":"Telmisartan","class":"ARB","usual_dose":"40-80 mg once daily","common_side_effects":"Dizziness, back pain, diarrhea"},{"medicine":"Olmesartan medoxomil","class":"ARB","usual_dose":"20-40 mg once daily","common_side_effects":"Dizziness, headache, tiredness"}]

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