Abel 80 Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of face, lips, tongue, or throat, or difficulty breathing.
- Severe dizziness or fainting.
- Decreased urine output or swelling in legs.
- Muscle weakness or irregular heartbeat.
- Yellowing of skin or eyes, or dark urine.
- Severe abdominal pain or persistent vomiting.
- Chest pain or shortness of breath.
If experiencing severe symptoms, call emergency services immediately.
What is aztra 80mg tablet used for?
This medicine is an angiotensin II receptor blocker (ARB) used to treat high blood pressure. It works by relaxing blood vessels, allowing blood to flow more easily. The usual dose is 80 mg once daily, with or without food. It is not safe during pregnancy.
- Generic Name: Azilsartan medoxomil
- Manufacturer: HBC Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aztra 80mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह एंजियोटेंसिन II रिसेप्टर ब्लॉकर (ARB) वर्ग की दवा है, जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। यह दवा स्ट्रोक, दिल के दौरे और गुर्दे की समस्याओं के जोखिम को कम करने में मदद करती है। इसे अकेले या अन्य रक्तचाप की दवाओं के साथ लिया जा सकता है। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए क्योंकि यह भ्रूण को नुकसान पहुंचा सकती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के अभ्यस्त होने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया (चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई), गुर्दे की समस्या (पेशाब कम आना, पैरों में सूजन), उच्च पोटेशियम स्तर (मांसपेशियों में कमजोरी, अनियमित दिल की धड़कन) और निम्न रक्तचाप (बेहोशी, गंभीर चक्कर) शामिल हो सकते हैं। इनमें से कोई भी लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बदलें और न ही दवा लेना बंद करें। इस दवा के साथ शराब न पिएं क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। खूब पानी पिएं। अगर आपको गुर्दे या लीवर की बीमारी, मधुमेह है या आप अन्य दवाएं ले रहे हैं तो डॉक्टर को बताएं। गर्भवती होने या गर्भधारण की योजना बनाने पर तुरंत डॉक्टर को सूचित करें। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और पोटेशियम स्तर की जांच कराएं।
💊 aztra 80mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, either alone or in combination with other antihypertensive agents.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Heart failure with reduced ejection fraction","description":"Sometimes used off-label in patients who cannot tolerate ACE inhibitors or other ARBs, but evidence is limited.","evidence":"Limited"},{"condition":"Diabetic nephropathy","description":"May be used off-label to slow kidney damage in diabetic patients with hypertension, but not FDA-approved for this indication.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Heart failure (off-label), Diabetic nephropathy (off-label)
📋 Drug Information
| Generic Name(s) | Azilsartan medoxomil |
| Brand Name | Abel 40 Tablet |
| Manufacturer | HBC Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin receptor blockers(ARB) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place. Protect from moisture and light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends angiotensin receptor blockers (ARBs) as one of the first-line treatment options for hypertension in adults, especially when ACE inhibitors are not tolerated. Azilsartan is an ARB and is included in this class. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) guidelines for hypertension recommend ARBs as first-line therapy for hypertension, particularly in patients who cannot tolerate ACE inhibitors. Azilsartan is an option within this class. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Azilsartan medoxomil is a prodrug that is rapidly hydrolyzed to azilsartan, the active moiety. Azilsartan selectively blocks the binding of angiotensin II to the AT1 receptor subtype, which is found in many tissues including vascular smooth muscle and the adrenal gland. By blocking AT1 receptors, azilsartan inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to decreased peripheral vascular resistance, reduced aldosterone secretion, and lower blood pressure. It does not affect the AT2 receptor, which is involved in vasodilation and tissue repair.
Mechanism Steps
💡 How to Take aztra 80mg tablet
Strength: Azilsartan medoxomil 80 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The recommended starting dose of this medicine is 80 mg once daily, with or without food. For patients who are volume-depleted or at risk of hypotension, a lower starting dose may be considered. The dose may be adjusted based on blood pressure response. The maximum recommended dose is 80 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No dose adjustment is required based on age alone. However, elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. In patients with severe renal impairment or on dialysis, use with caution and monitor renal function and potassium levels. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No dose adjustment is required for mild to moderate hepatic impairment. Use is not recommended in patients with severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 80 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aztra 80mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aliskiren | Major | |
| Potassium-sparing diuretics | Major | |
| Potassium supplements | Major | |
| NSAIDs | Major | |
| Lithium | Major | |
| Diuretics | Moderate | |
| ACE inhibitors | Moderate | |
| Other ARBs | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Aliskiren
- Potassium-sparing diuretics (e.g., spironolactone, triamterene)
- Potassium supplements
- NSAIDs (e.g., ibuprofen, naproxen)
- Lithium
⚡ Moderate Interactions
- Diuretics (e.g., hydrochlorothiazide, furosemide)
- ACE inhibitors (e.g., lisinopril, enalapril)
- Other ARBs (e.g., losartan, valsartan)
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol or limit its consumption while taking this medicine. If you choose to drink, do so in moderation and monitor your blood pressure.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Hypersensitivity to azilsartan or any component of the formulation","History of angioedema with ARBs or ACE inhibitors","Severe hepatic impairment","Concomitant use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["Fetal toxicity: Discontinue as soon as pregnancy is detected.","Hypotension: May occur in volume-depleted or salt-depleted patients. Correct volume depletion before initiating therapy.","Hyperkalemia: Risk increased with renal impairment, diabetes, and concomitant potassium-sparing diuretics or supplements.","Renal impairment: May cause oliguria, progressive azotemia, and acute renal failure. Monitor renal function.","Dual blockade of the renin-angiotensin system: Increased risk of hypotension, hyperkalemia, and renal impairment. Avoid concomitant use with ACE inhibitors or aliskiren.","Angioedema: Rare but serious. Discontinue immediately if angioedema occurs."]
🤱 Lactation Safety
It is not known whether azilsartan is excreted in human breast milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose may cause severe hypotension and tachycardia. If overdose occurs, discontinue the medicine and seek immediate medical attention. Treatment is supportive and symptomatic. If hypotension occurs, place the patient in supine position and administer intravenous fluids if necessary. Azilsartan is not removed by hemodialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Avoid alcohol while taking this medicine as it may increase dizziness and low blood pressure. Drink plenty of water to stay hydrated, especially in hot weather or during exercise. Inform your doctor if you have kidney or liver disease, diabetes, or are taking other medications, especially diuretics, NSAIDs, or potassium supplements. Do not take potassium supplements or salt substitutes containing potassium without your doctor's approval. If you are pregnant or planning to become pregnant, tell your doctor immediately; this medicine can harm the fetus. Use effective contraception while taking this medicine. Regular monitoring of blood pressure, kidney function, and potassium levels is important. Do not drive or operate heavy machinery if you feel dizzy after taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor blood pressure closely. Renal function should be monitored regularly as kidney function declines with age.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to prevent low blood pressure during the procedure. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause low blood pressure or dizziness during dental procedures. Your dentist may take precautions such as monitoring your blood pressure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but avoid sudden strenuous activities if you are not used to them, as they may cause dizziness or low blood pressure. Stay hydrated during exercise. If you experience dizziness, chest pain, or shortness of breath during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people, especially when standing up quickly. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your daily activities, but take precautions if you feel lightheaded. Inform your employer if your job involves operating machinery or working at heights.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as angioedema, severe hypotension, or kidney problems, seek immediate medical attention and your doctor may advise stopping the medicine. If you become pregnant, stop this medicine immediately and contact your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, kidney function, and potassium levels is recommended. In some patients, long-term use may lead to mild increases in serum creatinine or potassium. Rarely, it may cause liver enzyme elevations. Adherence to lifestyle modifications and regular follow-up with your doctor are important for optimal outcomes.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, calcium channel blockers, diuretics, and beta-blockers are alternatives if ARBs are not suitable.
Evidence: Well-establishedAn interventional procedure for resistant hypertension, but not widely available.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C).
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for your entire trip and a little extra in case of delays. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 2 weeks, with maximal effect after 4 weeks.
A: Yes, you can take it with or without food.
A: If you remember within 12 hours, take it. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping can cause it to rise again.
A: No, this medicine is contraindicated during pregnancy as it can harm the unborn baby.
🤔 Common Patient Concerns
🔄 Substitutes for aztra 80mg tablet
View AllAlternative brands with exact same active ingredient:
-
azipress 80mg tabletLividus Pharmaceuticals Pvt Ltd ₹112.50 12.8% CHEAPER
-
macarbi 80 tabletMacleods Pharmaceuticals Pvt Ltd ₹125.63 2.6% CHEAPER
-
zilatax 80mg tabletAjanta Pharma Ltd ₹126.56 1.9% CHEAPER
-
azilday tabletUSV Ltd ₹130.00 0.8% COSTLIER
-
aziltrend 80 tabletAbbott ₹130.31 1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure permanently.
Fact: This medicine helps manage high blood pressure but does not cure it. Lifestyle changes and long-term medication are often needed. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping medication can cause it to rise again. Always consult your doctor before stopping. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is contraindicated during pregnancy as it can harm the unborn baby. - Myth: This medicine can be taken with any other blood pressure medicine.
Fact: Combining with certain medicines like ACE inhibitors or aliskiren can increase risks. Always consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Azilsartan medoxomil 80 mg tablet (generic)
Brand Alternatives
- Abel 80 Tablet