unipride 10mg tablet - Cisapride (10mg) medicine

Esorid 10mg Tablet (Cisapride): Complete Medicine Guide

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🏭 Torrent Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for GERD and functional dyspepsia; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Fainting or loss of consciousness
  • Palpitations or irregular heartbeat
  • Severe dizziness or lightheadedness
  • Swelling of the face, lips, or throat
  • Difficulty breathing
  • Severe abdominal pain or vomiting blood
  • Bloody diarrhea
  • Yellowing of the skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is unipride 10mg tablet used for?

This medicine contains Cisapride 10 mg, a prokinetic agent used to treat gastroesophageal reflux disease, functional dyspepsia, and gastroparesis. It works by increasing acetylcholine release in the gut to improve stomach emptying and reduce reflux. It can cause serious heart rhythm problems, so it is used only under medical supervision with ECG monitoring.

  • Generic Name: Cisapride (10mg)
  • Manufacturer: Torrent Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 unipride 10mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सिसाप्राइड 10 मिलीग्राम युक्त एक प्रोकाइनेटिक एजेंट है, जिसका उपयोग गैस्ट्रोएसोफेजियल रिफ्लक्स रोग (जीईआरडी), कार्यात्मक अपच और गैस्ट्रोपेरेसिस जैसी स्थितियों में किया जाता है। यह पेट और आंतों की गति को बढ़ाकर भोजन को जल्दी आगे बढ़ाने में मदद करती है, जिससे सीने में जलन, पेट फूलना, मतली और जल्दी पेट भरने जैसे लक्षण कम होते हैं। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए क्योंकि यह दिल की धड़कन को प्रभावित कर सकती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में ऐंठन, दस्त, मतली, सिरदर्द और शौच की संख्या बढ़ना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें दिल की धड़कन में गड़बड़ी, बेहोशी, चक्कर आना और एलर्जी की प्रतिक्रिया शामिल हो सकती है। अगर आपको धड़कन तेज या अनियमित महसूस हो, बेहोशी आए, या चेहरे, होंठ या गले में सूजन हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर के पर्चे पर ही लें। अपने आप से दवा शुरू, बंद या उसकी मात्रा न बदलें। इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर एंटीबायोटिक, एंटीफंगल, अवसादरोधी और दिल की दवाएं। डॉक्टर आपका ईसीजी और खून की जांच कर सकते हैं। इस दवा के साथ शराब न लें। गर्भावस्था या स्तनपान के दौरान इस दवा को बिना डॉक्टर की सलाह के न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 unipride 10mg tablet Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine increases lower esophageal sphincter pressure and speeds up stomach emptying, which reduces acid reflux and heartburn symptoms in adults who have not responded to other treatments.","evidence":"Moderate"},{"condition":"Functional dyspepsia","description":"It helps relieve symptoms such as upper abdominal bloating, early satiety, and nausea by improving gastric emptying and gut movement.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"This medicine stimulates stomach contractions and improves emptying in patients with delayed gastric emptying, including some cases related to diabetes.","evidence":"Limited"},{"condition":"Chronic constipation","description":"It can increase bowel movement frequency by promoting coordinated intestinal motility, but it is not a first-line treatment for constipation.","evidence":"Limited"}]

Off-label uses: [{"condition":"Intestinal pseudo-obstruction","description":"Sometimes used in specialist settings to improve gut motility when no mechanical blockage is present.","evidence":"Limited"},{"condition":"Feeding intolerance in critically ill patients","description":"Occasionally considered to help improve tolerance of tube feeding by speeding up gastric emptying.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Functional dyspepsia, Gastroparesis, Chronic constipation

📋 Drug Information

Generic Name(s)Cisapride (10mg)
Brand Nameunipride 10mg tablet
ManufacturerTorrent Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin (5-HT4) receptor agonist-Prokinetic agent
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container.
Shelf LifeNot established from the available information. Check the expiry date on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always check an ECG before starting this medicine and monitor the QT interval during treatment.
2
Correct any low potassium or magnesium levels before starting this medicine.
3
Review all concomitant medicines for CYP3A4 inhibition and QT prolongation before prescribing.
4
Use this medicine only when other prokinetic agents have failed or are not suitable.
5
Advise patients to avoid grapefruit juice and alcohol while taking this medicine.
6
Consider alternative treatments in elderly patients and those with heart disease.
7
Instruct patients to report palpitations, fainting, or dizziness immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly prescribed for GERD.
Likely Use
Bloating and early fullness
This medicine helps improve gastric emptying.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract after oral administration. Food may increase the rate and extent of absorption, but specific pharmacokinetic values are not established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismThis medicine is extensively metabolized in the liver, mainly by the cytochrome P450 3A4 enzyme. This is important because medicines that inhibit CYP3A4 can raise its blood levels and increase the risk of serious heart rhythm problems.
Half-LifeNot established from the available information.
ExcretionThis medicine and its metabolites are excreted mainly in the urine and feces. Specific proportions are not established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action is not established from the available information, but symptom improvement may be noticed within a few days of starting treatment.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine is a prokinetic agent that works by stimulating the release of acetylcholine from the myenteric plexus in the gastrointestinal tract. It acts as a serotonin 5-HT4 receptor agonist and also has some 5-HT3 receptor antagonist activity. By increasing acetylcholine release, it enhances coordinated contractions of the stomach and intestines, raises lower esophageal sphincter pressure, and accelerates gastric emptying without directly stimulating acid secretion.

Mechanism Steps

1
Binding to 5-HT4 receptors: This medicine binds to serotonin 5-HT4 receptors on enteric neurons in the gastrointestinal tract.
2
Increased acetylcholine release: Activation of these receptors leads to increased release of acetylcholine from the myenteric plexus.
3
Enhanced gut motility: The increased acetylcholine causes stronger and more coordinated contractions of the stomach and intestines.
4
Improved emptying and reflux control: This results in faster gastric emptying, higher lower esophageal sphincter pressure, and reduced reflux symptoms.
5
Cardiac ion channel effect: This medicine can also block potassium channels in the heart, which may prolong the QT interval and, in rare cases, cause dangerous heart rhythms.

💡 How to Take unipride 10mg tablet

Strength: Immediate-release tablet containing Cisapride 10 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it at the same times each day, preferably before meals as advised.
4Do not crush, chew, or break the tablet unless your doctor says it is okay.
5If you miss a dose, follow the missed dose instructions.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is individualized by a qualified clinician based on the condition being treated, your age, weight, kidney and liver function, and your response to treatment. A typical starting dose may be 5 mg to 10 mg taken two to four times a day before meals, but this must be confirmed by your doctor. Do not adjust the dose yourself. Your doctor may perform an ECG before starting and may change the dose based on your heart rhythm and symptom control.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially heart rhythm problems. The dose should be individualized by a qualified clinician, and ECG monitoring is recommended. Use with caution and only when clearly needed.
Renal ImpairmentDose adjustment may be required in patients with kidney disease because this medicine and its metabolites are excreted by the kidneys. Your doctor will determine the appropriate dose based on your kidney function.
Hepatic ImpairmentThis medicine is extensively metabolized in the liver. Dose reduction or avoidance may be necessary in patients with liver disease. Your doctor will decide the appropriate dose based on your liver function.
Maximum Daily DoseThe maximum daily dose is not established from the available information. It must be determined by a qualified clinician based on your condition and response.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take as advised by your doctor
Food may increase absorption; consistency is important.
Grapefruit
Avoid
May increase drug levels and risk of heart rhythm problems.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of unipride 10mg tablet

✅ Common Side Effects

Abdominal cramps (Common (5-10%))
Usually settles with continued use. If cramps are severe or persistent, contact your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or lasts more than 2 days, consult your doctor.
Nausea (Common (5-10%))
Take the tablet with a small snack if allowed. If nausea persists, speak to your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if the headache is severe or unusual.
Increased bowel movements (Common (5-10%))
This often improves with time. Report any bloody stools or severe urgency to your doctor.

🚨 Serious Side Effects

QT prolongation and torsades de pointes (Rare (<0.1%))
Seek emergency medical help if you experience fainting, palpitations, or irregular heartbeat.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Stop the medicine and call emergency services if you have swelling of the face, lips, or throat, or difficulty breathing.
Neuroleptic malignant syndrome-like reaction (Very rare (<0.01%))
Seek immediate medical attention for high fever, muscle rigidity, confusion, or sweating.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care immediately.
Liver enzyme elevation
Your doctor may monitor liver tests if you develop jaundice or abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Clarithromycin Major
Amiodarone Major
Fluoxetine Major
Furosemide Major
Grapefruit juice Moderate
Cimetidine Moderate
Oxybutynin Moderate
Antacids Minor
Food Minor

🚨 Major Interactions

  • Ketoconazole, itraconazole, clarithromycin, erythromycin, ritonavir
  • Amiodarone, sotalol, quinidine, procainamide, disopyramide
  • Antidepressants such as fluoxetine, paroxetine, sertraline, amitriptyline
  • Diuretics that cause potassium loss (e.g., furosemide, hydrochlorothiazide)

⚡ Moderate Interactions

  • Grapefruit juice
  • Cimetidine
  • Anticholinergic medicines (e.g., hyoscyamine, oxybutynin)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Alcohol can worsen side effects such as dizziness, drowsiness, and stomach upset, and it may increase the risk of heart rhythm disturbances. It is best to discuss alcohol use with your doctor before starting this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cisapride or any component of the tablet","History of QT prolongation or congenital long QT syndrome","Current use of medicines that prolong the QT interval or inhibit CYP3A4","Severe heart disease such as recent heart attack, heart failure, or arrhythmias","Low potassium or magnesium levels that are not corrected","Mechanical obstruction, perforation, or severe bleeding in the gastrointestinal tract","Severe liver disease","Pregnancy and breastfeeding unless specifically advised by a doctor"]

⚠️ Warnings & Precautions

["This medicine can cause serious heart rhythm problems. It should only be used when other treatments have not worked.","Your doctor may perform an ECG before starting and during treatment to check your heart rhythm.","Tell your doctor about all medicines you take, especially antibiotics, antifungals, and antidepressants.","Avoid alcohol while taking this medicine.","Do not take this medicine if you have low potassium or magnesium levels until they are corrected.","Use with caution in elderly patients, who may be more sensitive to side effects.","Do not use this medicine for longer than your doctor recommends without a review."]

🤱 Lactation Safety

Not established from the available information. This medicine may pass into breast milk, so breastfeeding is not recommended unless your doctor specifically advises it after weighing the benefits and risks.

💊 Overdose Management

Overdose of this medicine can cause severe heart rhythm disturbances, low blood pressure, and gastrointestinal symptoms. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include ECG monitoring, correction of electrolyte imbalances, and management of arrhythmias. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

This medicine must only be taken when prescribed by a qualified doctor, because it can affect the heart rhythm. Do not start, stop, or change the dose on your own. Before starting, tell your doctor about all other medicines you take, especially antibiotics, antifungals, antidepressants, and heart medicines, as many of them can interact dangerously. Your doctor may arrange an ECG and blood tests to check potassium and magnesium levels before and during treatment. Avoid alcohol while taking this medicine because it can worsen side effects and increase the risk of heart rhythm problems. Do not take this medicine if you are pregnant or breastfeeding unless your doctor specifically advises it. Keep all follow-up appointments so your doctor can monitor your response and check for any heart-related changes.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of heart rhythm problems and electrolyte imbalances. Use with caution, lower doses may be needed, and ECG monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss this medicine with your doctor before conception. It should only be used if clearly needed and under medical supervision.

🏥 Post-Surgery Considerations

This medicine may affect gut motility after surgery. Use only if prescribed by your surgeon or doctor, and inform them if you are taking it before any surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medicines used during dental procedures. No specific precautions are established.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals to reduce reflux.
🥗
Avoid lying down for at least 2 hours after eating.
😴
Elevate the head of your bed if you have night-time reflux.
💧
Maintain a healthy weight.
🧘
Avoid smoking and alcohol.
🌞
Manage stress with relaxation techniques.

🏋️ Exercise Considerations

Moderate exercise is generally safe, but avoid strenuous activity immediately after meals. If you experience dizziness or palpitations during exercise, stop and consult your doctor.

🥗 Diet Recommendations

Avoid spicy, fatty, and acidic foods that worsen reflux.
Eat smaller meals more frequently.
Stay well hydrated.
Avoid grapefruit and grapefruit juice.
Limit caffeine and carbonated drinks.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or palpitations in some people. Avoid driving or operating heavy machinery until you know how it affects you. If you experience any heart-related symptoms, stop and seek medical advice.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as fainting, palpitations, or allergic reactions, stop the medicine and seek emergency medical help immediately. Your doctor will decide if and when to stop treatment.

📅 Long-Term Use Effects

Long-term use of this medicine may require regular monitoring of heart rhythm, electrolytes, and liver function. Prolonged use should be reviewed periodically by your doctor to ensure it is still necessary and safe. Do not stop or continue long-term use without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Dietary changes, weight loss, and elevating the head of the bed can help reduce reflux symptoms.

Evidence: Well-established
Proton pump inhibitors

These medicines reduce stomach acid and are often first-line for GERD.

Evidence: Well-established
Other prokinetic agents

Domperidone or metoclopramide may be considered as alternatives, depending on the patient.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Discuss with your doctor if you are due for any vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations for carrying prescription medicines. Store away from direct sunlight and moisture.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with chronic GERD not responding to proton pump inhibitors
He was started on this medicine after a normal ECG and electrolyte check. Within a week, his heartburn and bloating improved significantly. He was advised to avoid grapefruit juice and alcohol. He reported mild diarrhea initially, which settled after a few days. Regular follow-up and ECG monitoring were done.
💡 Lesson: This medicine can be effective for GERD when other treatments fail, but it requires careful monitoring and lifestyle adjustments.
👤 A 60-year-old woman with diabetic gastroparesis
She had persistent nausea and early fullness. After starting this medicine, her symptoms improved, but she developed palpitations. An ECG showed QT prolongation, and the medicine was stopped. She was switched to an alternative prokinetic agent and her symptoms were managed safely.
💡 Lesson: Serious heart rhythm side effects can occur even with proper use. Immediate reporting of palpitations and regular ECG monitoring are essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Symptom improvement may be noticed within a few days, but the full effect may take longer. Your doctor will monitor your response.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I take this medicine with other medicines?

A: Many medicines can interact with this medicine, especially antibiotics, antifungals, and antidepressants. Always inform your doctor about all medicines you take.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for unipride 10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a simple antacid.
    Fact: This medicine is not an antacid. It is a prokinetic agent that improves gut movement and can affect heart rhythm.
  • Myth: This medicine is safe for everyone.
    Fact: This medicine can cause serious heart rhythm problems and is contraindicated in many patients. It should only be used under medical supervision.
  • Myth: You can stop this medicine whenever you feel better.
    Fact: You should not stop this medicine without consulting your doctor, as sudden discontinuation may worsen symptoms and your doctor needs to monitor your heart rhythm.

🔄 Alternative Options

Generic Alternatives

  • Cisapride 10 mg tablet

Brand Alternatives

  • Esorid 10mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cisapride","class":"5-HT4 agonist","main_use":"GERD, dyspepsia, gastroparesis","cardiac_risk":"High","notes":"Requires ECG monitoring; many interactions."},{"medicine":"Domperidone","class":"Dopamine antagonist","main_use":"Nausea, gastroparesis","cardiac_risk":"Moderate","notes":"Less QT risk than cisapride but still caution."},{"medicine":"Metoclopramide","class":"Dopamine antagonist","main_use":"Nausea, gastroparesis","cardiac_risk":"Low","notes":"Risk of movement disorders with long-term use."}]

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