Tricold 8mg/50mg Capsule SR - Chlorpheniramine Maleate (8mg) + Phenylpropanolamine (50mg) medicine

Tricold 8mg/50mg Capsule SR: Complete Medicine Guide

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🏭 Bhavishya Pharmaceuticals Pvt Ltd 📦 strip of 25 capsule sr 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Severe headache with blurred vision
  • Inability to urinate or painful urination
  • Unusual bleeding or bruising
  • Seizures or convulsions
  • Severe drowsiness or confusion

If experiencing severe symptoms, call emergency services immediately.

What is Tricold 8mg/50mg Capsule SR used for?

This medicine is a combination of Chlorpheniramine Maleate 8 mg and Phenylpropanolamine 50 mg used for temporary relief of allergic rhinitis and common cold symptoms. It works by blocking histamine and reducing nasal congestion. It is intended for short-term use in adults and children above 12 years.

  • Generic Name: Chlorpheniramine Maleate (8mg) + Phenylpropanolamine (50mg)
  • Manufacturer: Bhavishya Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Tricold 8mg/50mg Capsule SR के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी राइनाइटिस और सामान्य सर्दी-जुकाम के लक्षणों जैसे छींक, नाक बहना, नाक बंद होना, आंखों में खुजली और पानी आना को कम करने के लिए उपयोग की जाती है। यह क्लोरफेनिरामाइन मेलिएट और फेनिलप्रोपेनॉलामाइन का संयोजन है। यह दवा केवल अल्पकालिक उपयोग के लिए है और डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, धुंधली दृष्टि और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभावों में तेज धड़कन, उच्च रक्तचाप, पेशाब रुकना और एलर्जी प्रतिक्रिया शामिल हो सकते हैं। यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, सीने में दर्द या अनियमित धड़कन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित मात्रा से अधिक न लें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। इस दवा के साथ शराब न लें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या पेशाब करने में कठिनाई है तो डॉक्टर को बताएं। 7 दिनों से अधिक उपयोग से पहले डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 Tricold 8mg/50mg Capsule SR Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion, sneezing, and runny nose due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Upper respiratory tract allergy","description":"Helps reduce allergic symptoms affecting the nose, throat, and eyes.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Motion sickness","description":"Chlorpheniramine may be used off-label for prevention of motion sickness due to its antihistamine effects.","evidence":"Limited"},{"condition":"Insomnia","description":"Sometimes used off-label for short-term management of insomnia due to drowsiness side effect.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Upper respiratory tract allergy

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (8mg) + Phenylpropanolamine (50mg)
Brand NameTricold 8mg/50mg Capsule SR
ManufacturerBhavishya Pharmaceuticals Pvt Ltd
Packaging / Formstrip of 25 capsule sr (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not take this medicine for more than 7 days without consulting your doctor.
4
Avoid alcohol and other CNS depressants while taking this medicine.
5
Inform your doctor if you have high blood pressure, heart disease, diabetes, or thyroid problems.
6
Do not exceed the recommended dose; taking more can increase side effects.
7
If you miss a dose, take it as soon as you remember, but do not double dose.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
This medicine helps reduce runny nose.
Likely Use
✅
Nasal congestion
This medicine contains a decongestant for nasal congestion.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Body ache
This medicine is not indicated for body ache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine is well absorbed from the gastrointestinal tract. Phenylpropanolamine is also absorbed orally. Food may delay absorption slightly.
DistributionChlorpheniramine distributes widely into body tissues and crosses the blood-brain barrier. Phenylpropanolamine distributes to various tissues but its distribution volume is not well established.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Protein binding of phenylpropanolamine is not established from the available information.
MetabolismChlorpheniramine is metabolized in the liver via cytochrome P450 enzymes, primarily CYP2D6. Phenylpropanolamine undergoes minimal hepatic metabolism.
Half-LifeChlorpheniramine elimination half-life is approximately 12-43 hours. Phenylpropanolamine half-life is approximately 3-7 hours.
ExcretionChlorpheniramine and its metabolites are excreted primarily in urine. Phenylpropanolamine is excreted largely unchanged in urine.
BioavailabilityChlorpheniramine oral bioavailability is approximately 25-50%. Phenylpropanolamine bioavailability is not well established from the available information.
Onset of ActionOnset of action for chlorpheniramine is within 30-60 minutes. Phenylpropanolamine onset is within 15-30 minutes.
Peak Plasma TimePeak plasma concentration for chlorpheniramine is about 2-6 hours. For phenylpropanolamine, peak is about 1-2 hours.
Duration of ActionDuration of action for chlorpheniramine is about 4-6 hours. For phenylpropanolamine, it is about 3-4 hours.

How It Works

Chlorpheniramine Maleate competitively blocks histamine H1 receptors, reducing allergic symptoms. Phenylpropanolamine stimulates alpha-adrenergic receptors, causing vasoconstriction in nasal mucosa and reducing congestion.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on effector cells, preventing histamine from triggering allergic responses like sneezing and vasodilation.
2
Alpha-adrenergic receptor stimulation: Phenylpropanolamine stimulates alpha-1 adrenergic receptors on nasal blood vessels, causing vasoconstriction and reduced swelling.
3
Reduced nasal congestion: Vasoconstriction decreases blood flow to nasal mucosa, shrinking swollen tissues and improving airflow.
4
Central nervous system effects: Chlorpheniramine crosses the blood-brain barrier and may cause sedation by blocking central H1 receptors.

💡 How to Take Tricold 8mg/50mg Capsule SR

Strength: Capsule containing Chlorpheniramine Maleate 8 mg and Phenylpropanolamine 50 mg.

1Take this medicine orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the capsule whole; do not crush or chew.
4Take at the same times each day if prescribed regularly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one capsule orally every 8 to 12 hours as needed for symptoms, not to exceed 3 capsules in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 7 days without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and urinary retention. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be required. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be required. Consult a doctor for individualized dosing.
Maximum Daily DoseMaximum daily dose is 3 capsules in 24 hours for adults. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases sedation and cardiovascular risks.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Tricold 8mg/50mg Capsule SR

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-15%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid sudden movements.
Blurred vision (Common (5-10%))
Avoid tasks requiring clear vision until effect subsides.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or trouble breathing.
Hypertensive crisis (Rare (<0.1%))
Seek emergency care if you have severe headache, blurred vision, chest pain, or difficulty speaking.
Urinary retention (Rare (<0.1%))
Consult a doctor if you are unable to urinate or have painful urination.
Blood dyscrasias (Very rare (<0.01%))
Report unusual bleeding, bruising, fever, or sore throat to your doctor immediately.
Seizures (Very rare (<0.01%))
Seek emergency medical help if seizures occur.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek immediate medical attention.
Arrhythmias
Seek emergency care if you experience palpitations, fainting, or irregular heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Sympathomimetics Major
Tricyclic antidepressants Major
Alcohol Moderate
Other antihistamines Moderate
Beta-blockers Moderate
Caffeine Minor
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Other sympathomimetics
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Alcohol
  • Other antihistamines
  • Beta-blockers

🍷 Alcohol Interaction

Alcohol increases the sedative effects of chlorpheniramine and may enhance cardiovascular effects of phenylpropanolamine. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, phenylpropanolamine, or any component","Severe hypertension or coronary artery disease","Hyperthyroidism","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Concurrent use with MAOIs","Children under 12 years"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, or thyroid disorders.","Do not exceed recommended dose or duration of use.","Consult a doctor if symptoms persist beyond 7 days.","May cause urinary retention in susceptible individuals.","Not recommended for children under 12 years."]

🤱 Lactation Safety

Chlorpheniramine and phenylpropanolamine may pass into breast milk. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, hypertension, tachycardia, hallucinations, seizures, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects. Use with caution, lower doses may be needed. Monitor for urinary retention, confusion, and falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy or if you become pregnant while taking this medicine. The risks and benefits should be assessed individually.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents and affect blood pressure.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may cause dry mouth and interact with local anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Avoid allergens such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Stay hydrated to help thin nasal secretions.
💧
Get adequate rest to support immune function.
🧘
Practice good hand hygiene to prevent infections.
🌞
Use saline nasal rinses to relieve congestion.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience dizziness or drowsiness. Stay hydrated during exercise. Consult your doctor before starting any exercise regimen while on this medicine.

🥗 Diet Recommendations

Include vitamin C-rich foods like oranges and bell peppers.
Consume warm fluids like soups and herbal teas.
Avoid alcohol and caffeine.
Eat a balanced diet to support immune health.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and dizziness, affecting your ability to drive or operate machinery. Avoid tasks requiring alertness until you know how it affects you. Inform your employer if your work involves operating heavy machinery.

🛑 When to Stop This Medicine

Stop taking this medicine if symptoms resolve or if you experience severe side effects. Do not stop abruptly if you have been taking it for a long time without consulting your doctor. Consult your doctor before stopping if you have underlying conditions.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to risks of tolerance, dependence, and cardiovascular effects. Prolonged use may lead to rebound congestion, hypertension, and urinary retention. Regular monitoring of blood pressure and renal function is advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps relieve nasal congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease symptoms.

Evidence: Well-established
Intranasal corticosteroids

Prescription nasal sprays for allergic rhinitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature during travel. If crossing time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications. Avoid driving if you experience drowsiness.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis
She started this medicine as prescribed for her sneezing and runny nose. Within 30 minutes, her symptoms improved significantly. She experienced mild drowsiness, so she took it at bedtime. She was advised not to drive after taking it.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while providing symptom relief.
👤 A 50-year-old man with common cold and nasal congestion
He took this medicine for 3 days and found relief from nasal congestion and sneezing. He was cautioned about his high blood pressure, and his doctor monitored his BP regularly. He avoided alcohol and caffeine during treatment.
💡 Lesson: Patients with hypertension should use this medicine with caution and under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral intake.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe for children?

A: This medicine is not recommended for children under 12 years. Consult a pediatrician.

Q: Can I take it with other cold medicines?

A: Avoid taking with other antihistamines or decongestants unless advised by a doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic allergies.
    Fact: This medicine is for short-term use only. Long-term use requires medical supervision.
  • Myth: It is safe to drive after taking this medicine.
    Fact: This medicine may cause drowsiness. Avoid driving until you know how it affects you.
  • Myth: It can be taken with alcohol without any issues.
    Fact: Alcohol increases sedation and cardiovascular risks. Avoid alcohol.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine Maleate + Phenylpropanolamine capsules

📊 Comparison with Similar Medicines

[{"medicine":"Tricold 8mg/50mg Capsule SR","active_ingredients":"Chlorpheniramine Maleate 8mg + Phenylpropanolamine 50mg","class":"Antihistamine + Decongestant","primary_use":"Allergic rhinitis, common cold","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine + Pseudoephedrine","active_ingredients":"Cetirizine 5mg + Pseudoephedrine 120mg","class":"Antihistamine + Decongestant","primary_use":"Allergic rhinitis","sedation":"Low","duration":"12-24 hours"},{"medicine":"Loratadine + Pseudoephedrine","active_ingredients":"Loratadine 10mg + Pseudoephedrine 240mg","class":"Antihistamine + Decongestant","primary_use":"Allergic rhinitis","sedation":"Low","duration":"24 hours"}]

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