avispas 20mg/500mg tablet - Dicyclomine (20mg) + Paracetamol (500mg) medicine

Abdospas 20mg/500mg Tablet: Complete Medicine Guide

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🏭 Bhavishya Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for IBS; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Fast or irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is avispas 20mg/500mg tablet used for?

This medicine is a combination of dicyclomine and paracetamol used to treat abdominal cramps and pain associated with irritable bowel syndrome and other gastrointestinal spasms. It works by relaxing gut muscles and relieving pain.

  • Generic Name: Dicyclomine + Paracetamol
  • Manufacturer: Bhavishya Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 avispas 20mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पेट की ऐंठन और दर्द के इलाज के लिए इस्तेमाल की जाती है, जो अक्सर इरिटेबल बाउल सिंड्रोम (IBS) और अन्य पेट की समस्याओं में होती है। यह पेट की मांसपेशियों को आराम देकर दर्द कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, चक्कर आना, नींद आना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, पेशाब में रुकावट, तेज़ धड़कन या लीवर की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। शराब न पिएं। अगर आपको चक्कर या नींद आती है तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 avispas 20mg/500mg tablet Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal cramps and pain associated with IBS by reducing smooth muscle spasms in the gut.","evidence":"Well-established"},{"condition":"Functional gastrointestinal disorders","description":"Used to ease discomfort and cramping in conditions like functional dyspepsia and spastic colon.","evidence":"Moderate"},{"condition":"Biliary colic","description":"May help relieve pain from gallbladder spasms, though definitive evidence is limited.","evidence":"Limited"},{"condition":"Renal colic","description":"Sometimes used as an adjunct for pain relief in kidney stone episodes, but not first-line.","evidence":"Limited"}]

Off-label uses: [{"condition":"Menstrual cramps","description":"Occasionally prescribed to relieve uterine cramps, but evidence is not robust.","evidence":"Limited"},{"condition":"Infant colic","description":"Not recommended due to safety concerns in infants.","evidence":"Not established"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Functional gastrointestinal disorders, Biliary colic, Renal colic

📋 Drug Information

Generic Name(s)Dicyclomine + Paracetamol
Brand NameAbdospas 20mg/500mg Tablet
ManufacturerBhavishya Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic and Analgesic Combination
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not drive or operate machinery if you feel drowsy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer, though paracetamol has antipyretic effects.
Not Primary
❌
Diarrhea
This medicine may worsen diarrhea due to anticholinergic effects.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDicyclomine is well absorbed from the gastrointestinal tract. Paracetamol is rapidly and almost completely absorbed from the small intestine. Food may delay absorption of paracetamol but does not significantly reduce extent.
DistributionDicyclomine is widely distributed in body tissues, including the central nervous system. Paracetamol distributes throughout most body fluids, with relatively high concentrations in liver and kidney.
Protein BindingDicyclomine is approximately 80% bound to plasma proteins. Paracetamol is about 10-25% bound to plasma proteins.
MetabolismDicyclomine is extensively metabolized in the liver, primarily by oxidation and glucuronidation. Paracetamol is metabolized in the liver via glucuronidation and sulfation; a small fraction is oxidized by CYP2E1 to a toxic metabolite, NAPQI, which is detoxified by glutathione.
Half-LifeDicyclomine half-life is about 1.8 hours. Paracetamol half-life is 2-3 hours in normal adults.
ExcretionDicyclomine is excreted mainly in urine and feces as metabolites. Paracetamol is excreted in urine as glucuronide and sulfate conjugates.
BioavailabilityDicyclomine oral bioavailability is about 50-60%. Paracetamol oral bioavailability is approximately 80-90%.
Onset of ActionDicyclomine onset is within 1-2 hours. Paracetamol onset is within 30-60 minutes.
Peak Plasma TimeDicyclomine peak plasma levels occur at 1-2 hours. Paracetamol peak levels occur at 0.5-1 hour.
Duration of ActionDicyclomine effect lasts 4-6 hours. Paracetamol effect lasts 4-6 hours.

How It Works

Dicyclomine blocks muscarinic acetylcholine receptors in the gastrointestinal smooth muscle, reducing spasms and motility. Paracetamol acts centrally to inhibit prostaglandin synthesis, thereby reducing pain and fever. Together, they provide antispasmodic and analgesic effects.

Mechanism Steps

1
Dicyclomine binding: Dicyclomine competitively binds to muscarinic receptors on smooth muscle cells, preventing acetylcholine from binding.
2
Reduced smooth muscle contraction: This blockade decreases intracellular calcium and inhibits contraction, leading to relaxation of gastrointestinal smooth muscle.
3
Paracetamol central action: Paracetamol acts on central nervous system pathways to inhibit prostaglandin synthesis, reducing pain perception.
4
Combined effect: The combination alleviates both the spasm and the associated pain, providing relief from abdominal cramps.

💡 How to Take avispas 20mg/500mg tablet

Strength: Each tablet contains dicyclomine 20 mg and paracetamol 500 mg.

1Swallow the tablet whole with a glass of water.
2Take with food or milk to reduce stomach upset.
3Do not crush or chew the tablet.
4Take at the same times each day to maintain consistent levels.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally up to three times daily, or as directed by your physician. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to anticholinergic effects. Use with caution and lower doses may be needed. Consult your doctor.
Renal ImpairmentDicyclomine is excreted renally; dose adjustment may be needed in renal impairment. Consult your doctor.
Hepatic ImpairmentParacetamol and dicyclomine are metabolized in the liver; dose reduction may be necessary in hepatic impairment. Consult your doctor.
Maximum Daily DoseMaximum daily dose should not exceed 3 tablets in 24 hours, unless otherwise directed by your doctor. Do not exceed 4 grams of paracetamol per day from all sources.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage and drowsiness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of avispas 20mg/500mg tablet

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult if severe.
Blurred vision (Common (5-10%))
Usually temporary. Consult if persistent or severe.
Nausea (Common (5-10%))
Take with food. Consult if vomiting occurs.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult if no relief.

🚨 Serious Side Effects

Allergic reactions (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Urinary retention (Rare (<0.1%))
Consult doctor immediately if unable to urinate.
Fast or irregular heartbeat (Rare (<0.1%))
Seek medical attention.
Confusion or hallucinations (Rare (<0.1%))
Discontinue and consult doctor.
Liver damage (from paracetamol overdose) (Rare (<0.1%))
Seek emergency care if symptoms like yellowing of eyes or skin, dark urine, or severe abdominal pain occur.

⚠️ Rare Side Effects

Severe skin reactions (Stevens-Johnson syndrome)
Seek immediate medical attention.
Blood disorders (thrombocytopenia, leukopenia)
Consult doctor if unusual bleeding or bruising.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other anticholinergics Major
Alcohol Major
Metoclopramide Moderate
Cholestyramine Moderate
Antacids Minor

🚨 Major Interactions

  • Other anticholinergics (e.g., atropine, antihistamines, tricyclic antidepressants)
  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Metoclopramide
  • Cholestyramine

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage from paracetamol and enhance drowsiness and dizziness from dicyclomine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to dicyclomine, paracetamol, or any component","Glaucoma (narrow-angle)","Urinary retention","Myasthenia gravis","Severe liver disease","Paralytic ileus","Breastfeeding"]

⚠️ Warnings & Precautions

["Avoid in patients with obstructive uropathy.","Use with caution in elderly due to increased risk of anticholinergic effects.","Do not exceed recommended dose of paracetamol; risk of liver damage.","Avoid alcohol.","May impair ability to drive or operate machinery.","Consult doctor if symptoms persist beyond 7 days."]

🤱 Lactation Safety

Dicyclomine may pass into breast milk and could cause anticholinergic effects in the infant. Paracetamol is considered safe in breast milk. Consult your doctor before use.

💊 Overdose Management

Overdose can cause severe liver damage from paracetamol and anticholinergic toxicity from dicyclomine. Seek emergency medical help immediately. Treatment includes activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it can increase the risk of liver damage. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have glaucoma, prostate problems, kidney or liver disease, or if you are pregnant or breastfeeding. Do not use this medicine for more than the recommended duration without consulting your doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to anticholinergic side effects like confusion, dry mouth, and urinary retention. Use with caution and lower doses may be required. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy or are pregnant. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and affect postoperative recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Eat small, frequent meals to ease digestion.
😴
Avoid trigger foods like spicy, fatty, or gas-producing items.
💧
Practice stress-reduction techniques like yoga or meditation.
🧘
Get adequate sleep to help manage IBS symptoms.
🌞
Stay physically active with low-impact exercises.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or drowsy. Light activities like walking are generally safe. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Avoid caffeine and carbonated drinks.
Stay well hydrated.
Limit high-fat and spicy foods.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause dry mouth, which can be managed with frequent sips of water.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation is generally not associated with withdrawal, but medical guidance is recommended.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of paracetamol at high doses can cause liver and kidney damage. Dicyclomine may cause persistent dry mouth, constipation, or urinary issues. Regular monitoring of liver and kidney function may be advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary modifications

Low-FODMAP diet can help manage IBS symptoms.

Evidence: Well-established
Stress management

Cognitive behavioral therapy and relaxation techniques can reduce IBS flare-ups.

Evidence: Moderate
Probiotics

May help restore gut flora balance and reduce symptoms.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before any vaccination if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with IBS
She experienced frequent abdominal cramps and bloating. Her doctor prescribed this medicine. After taking it regularly with food, her cramps reduced significantly within a week. She also made dietary changes and felt much better.
💡 Lesson: Taking the medicine as prescribed and with food improves both efficacy and tolerability.
👤 A 50-year-old man with biliary colic
He had severe right upper abdominal pain. This medicine was given for symptomatic relief while awaiting surgery. It helped ease the pain, but he was advised to avoid fatty meals.
💡 Lesson: This medicine provides temporary relief but does not treat the underlying cause; definitive treatment may be needed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Dicyclomine starts working within 1-2 hours, and paracetamol within 30-60 minutes. You may feel relief from cramps and pain within a few hours.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take additional paracetamol-containing products without consulting your doctor, as this can lead to overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for avispas 20mg/500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure IBS permanently.
    Fact: It provides symptomatic relief but does not cure the underlying condition.
  • Myth: It is safe to take unlimited doses.
    Fact: Exceeding the recommended dose can cause serious liver damage from paracetamol.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine + Paracetamol generic tablets

Brand Alternatives

  • Abdospas 20mg/500mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Dicyclomine + Paracetamol","composition":"Dicyclomine 20mg + Paracetamol 500mg","uses":"IBS, abdominal cramps","notes":"Combination provides antispasmodic and analgesic effects."},{"medicine":"Dicyclomine alone","composition":"Dicyclomine 20mg","uses":"IBS, abdominal cramps","notes":"No analgesic component."},{"medicine":"Paracetamol alone","composition":"Paracetamol 500mg","uses":"Pain, fever","notes":"No antispasmodic effect."}]

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