telekast-t tablet cr - Montelukast (10mg) + Theophylline (400mg) medicine

Telekast-T Tablet CR: Complete Medicine Guide

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🏭 Lupin Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or palpitations
  • Seizures or convulsions
  • Difficulty breathing that does not improve with rescue inhaler
  • Yellowing of eyes or skin
  • Severe skin rash or blistering
  • Persistent vomiting or severe abdominal pain
  • Fainting or loss of consciousness

If experiencing severe symptoms, call emergency services immediately.

What is telekast-t tablet cr used for?

This medicine is a combination of Montelukast and Theophylline used to treat chronic asthma and COPD. It works by reducing airway inflammation and relaxing airway muscles. It is not for sudden breathing attacks.

  • Generic Name: Montelukast (10mg) + Theophylline (400mg)
  • Manufacturer: Lupin Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 telekast-t tablet cr के बारे में (Hindi Summary)

उपयोग: यह दवा मोंटेलुकास्ट और थियोफिलिन का संयोजन है, जिसका उपयोग दमा (अस्थमा) और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) के इलाज में किया जाता है। यह श्वास नलियों की सूजन को कम करती है और मांसपेशियों को आराम देकर सांस लेना आसान बनाती है। यह दवा अचानक होने वाले दमे के दौरे के लिए नहीं है; उसके लिए तुरंत असर करने वाला इनहेलर इस्तेमाल करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, उल्टी, पेट दर्द, बेचैनी और हल्का कंपन शामिल हैं। गंभीर दुष्प्रभावों में तेज़ धड़कन, अनियमित हृदय गति, दौरे, त्वचा पर गंभीर दाने और लीवर की समस्या हो सकती है। अगर आपको सीने में दर्द, बेहोशी, आंखों या त्वचा का पीलापन दिखे, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे चबाएं या तोड़ें नहीं। शराब और कैफीन का सेवन कम करें। बिना डॉक्टर की सलाह के कोई अन्य दवा शुरू या बंद न करें। अचानक सांस फूलने पर तुरंत इनहेलर का उपयोग करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। नियमित जांच और फॉलो-अप जरूरी है।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 telekast-t tablet cr Uses & Benefits

[{"condition":"Bronchial asthma","description":"Used as add-on maintenance therapy to reduce asthma symptoms and exacerbations in patients not controlled by inhaled corticosteroids alone.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps relieve bronchospasm and improve lung function in patients with COPD, though it is not a first-line therapy.","evidence":"Moderate"},{"condition":"Exercise-induced bronchoconstriction","description":"Montelukast component helps prevent narrowing of airways triggered by physical activity.","evidence":"Well-established for montelukast component"},{"condition":"Allergic rhinitis with asthma","description":"Montelukast provides relief from nasal allergy symptoms in patients who also have asthma.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Sleep-related breathing disorders","description":"Sometimes prescribed off-label for mild obstructive sleep apnea in children, but evidence is limited.","evidence":"Limited"},{"condition":"Urticaria","description":"Montelukast has been used off-label for chronic urticaria not responding to antihistamines.","evidence":"Limited"}]

Primary treatment for: Bronchial asthma

Also treats: Chronic obstructive pulmonary disease (COPD), Exercise-induced bronchoconstriction, Allergic rhinitis

📋 Drug Information

Generic Name(s)Montelukast (10mg) + Theophylline (400mg)
Brand Nametelekast-t tablet cr
ManufacturerLupin Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain steady blood levels.
2
Always carry a rescue inhaler for sudden breathing difficulty.
3
Avoid caffeine and alcohol while on this medicine.
4
Report any palpitations, tremors, or sleep disturbances to your doctor.
5
Do not stop this medicine without consulting your doctor, even if you feel better.
6
Keep a symptom diary to track your response to treatment.
7
Inform your doctor about all other medicines, especially antibiotics and heart medicines.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic wheezing
This medicine is commonly prescribed for this.
Likely Use
✅
Shortness of breath on exertion
May be used in COPD or asthma.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMontelukast is rapidly absorbed after oral administration, with peak plasma concentration reached in 3 to 4 hours. Theophylline absorption from immediate-release formulations is also rapid, with peak levels typically within 1 to 2 hours, but food may affect the rate. Not established from the available information for the specific fixed-dose combination.
DistributionMontelukast is highly protein-bound (more than 99%) and distributes into tissues. Theophylline distributes widely into body fluids and tissues, including the lungs, and crosses the placenta and blood-brain barrier. Not established from the available information for the specific fixed-dose combination.
Protein BindingMontelukast: approximately 99% bound to plasma proteins. Theophylline: approximately 40% bound to plasma proteins, mainly albumin.
MetabolismMontelukast is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C8 and CYP3A4. Theophylline is metabolized in the liver by CYP1A2 and CYP3A4, with some involvement of CYP2E1. Metabolism can be affected by liver disease, smoking, and interacting drugs.
Half-LifeMontelukast: 2.7 to 5.5 hours in healthy adults. Theophylline: 3 to 8 hours in healthy non-smoking adults, but can be longer in liver disease, heart failure, or the elderly.
ExcretionMontelukast is excreted mainly in bile and feces, with less than 0.2% excreted unchanged in urine. Theophylline is excreted in urine as metabolites and unchanged drug (about 10% unchanged in healthy adults).
BioavailabilityMontelukast: approximately 64% oral bioavailability. Theophylline: approximately 96% oral bioavailability for immediate-release formulations. Not established from the available information for the specific fixed-dose combination.
Onset of ActionMontelukast: bronchodilation begins within a few hours, but full anti-inflammatory effects may take days to weeks. Theophylline: bronchodilation occurs within 30 minutes to 2 hours after oral intake. Not established from the available information for the specific fixed-dose combination.
Peak Plasma TimeMontelukast: 3 to 4 hours. Theophylline: 1 to 2 hours for immediate-release. Not established from the available information for the specific fixed-dose combination.
Duration of ActionMontelukast: once-daily dosing provides 24-hour coverage. Theophylline: immediate-release formulations last 4 to 6 hours, requiring multiple daily dosing. Not established from the available information for the specific fixed-dose combination.

How It Works

This medicine combines two active ingredients with complementary actions. Montelukast selectively blocks cysteinyl leukotriene receptors (CysLT1) in the airways, preventing leukotriene-mediated bronchoconstriction, mucus secretion, and inflammation. Theophylline inhibits phosphodiesterase enzymes, increasing cyclic AMP levels, which leads to smooth muscle relaxation in the bronchi. Theophylline also blocks adenosine receptors, reducing airway hyperresponsiveness and improving diaphragmatic contractility. Together, they reduce airway obstruction and inflammation.

Mechanism Steps

1
Leukotriene receptor blockade: Montelukast binds to CysLT1 receptors on airway smooth muscle and inflammatory cells, preventing leukotrienes from causing bronchoconstriction and swelling.
2
Phosphodiesterase inhibition: Theophylline inhibits phosphodiesterase, raising cyclic AMP levels in airway smooth muscle, which promotes relaxation and widening of the airways.
3
Adenosine receptor antagonism: Theophylline blocks adenosine receptors, reducing bronchoconstriction and mast cell mediator release.
4
Anti-inflammatory synergy: The combined actions reduce airway inflammation, mucus plugging, and airway hyperresponsiveness, leading to better symptom control.

💡 How to Take telekast-t tablet cr

Strength: Tablet containing Montelukast 10 mg and Theophylline 400 mg (immediate release).

1Swallow the tablet whole with a glass of water.
2Take it at the same time each day for best results.
3Take with food to reduce stomach upset.
4Do not crush, chew, or break the tablet unless your doctor advises.
5If you miss a dose, follow the missed dose instructions.
6Keep a record of your doses and any side effects to discuss with your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, depending on the severity of the condition and theophylline blood levels. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and smoking status. Do not exceed the prescribed dose. Regular monitoring of theophylline levels is required to avoid toxicity.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced liver and kidney function. Theophylline clearance decreases with age, increasing the risk of toxicity. Dose must be individualized by a qualified clinician with close monitoring.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Theophylline is excreted by the kidneys, and accumulation can occur. Consult a clinician for individualized dosing.
Hepatic ImpairmentDose reduction is recommended in patients with hepatic impairment because both montelukast and theophylline are metabolized in the liver. Close monitoring is advised.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. For theophylline, the usual maximum is 400 mg per day for this combination, but individual limits vary. Do not exceed the dose recommended by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Caffeine
Limit
Can increase restlessness and heart rate.
Alcohol
Avoid
Increases risk of stomach bleeding and liver strain.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of telekast-t tablet cr

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food to reduce stomach upset. Consult doctor if vomiting occurs.
Stomach pain (Common (5-10%))
Take with meals. If pain is severe or persistent, contact your doctor.
Restlessness (Common (5-10%))
Avoid caffeine. If it interferes with sleep, talk to your doctor.
Tremors (Common (5-10%))
Usually dose-related. Report to doctor if bothersome.

🚨 Serious Side Effects

Fast or irregular heartbeat (Uncommon (0.1-1%))
Seek immediate medical attention if you feel palpitations, chest pain, or fainting.
Seizures (Rare (<0.1%))
This is a medical emergency. Call emergency services immediately.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop the medicine and seek immediate medical help if you notice rash, blisters, or peeling skin.
Liver injury (Rare (<0.1%))
Report yellowing of eyes or skin, dark urine, or severe abdominal pain to your doctor immediately.

⚠️ Rare Side Effects

Severe allergic reaction (anaphylaxis)
Seek emergency care if you experience swelling of face, lips, throat, or difficulty breathing.
Hallucinations or mood changes
Contact your doctor if you notice unusual thoughts, depression, or sleep disturbances.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Fluconazole Major
Rifampicin Major
Phenytoin Moderate
Carbamazepine Moderate
Propranolol Moderate
Furosemide Moderate
Cimetidine Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin
  • Fluconazole
  • Rifampicin

⚡ Moderate Interactions

  • Phenytoin
  • Carbamazepine
  • Propranolol
  • Furosemide

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of stomach bleeding, worsen liver strain, and may affect theophylline metabolism, leading to unpredictable drug levels. It can also add to central nervous system effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to montelukast, theophylline, or any component of the formulation","Active peptic ulcer disease","Uncontrolled cardiac arrhythmias","Severe liver disease","Children under 12 years for this strength (unless specifically prescribed)"]

⚠️ Warnings & Precautions

["Do not use for acute asthma attacks; keep a rescue inhaler available.","Theophylline has a narrow therapeutic index; regular blood level monitoring is essential.","Avoid alcohol and caffeine-containing products.","Use with caution in patients with heart disease, liver disease, kidney disease, or seizure disorders.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor about all other medicines you are taking, including over-the-counter products."]

🤱 Lactation Safety

Montelukast is excreted in breast milk in small amounts; caution is advised. Theophylline is excreted in breast milk and can cause irritability or insomnia in the infant. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose can cause severe nausea, vomiting, rapid heartbeat, seizures, and cardiac arrest. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal, antiarrhythmics, and management of seizures. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not crush or chew the tablet unless your doctor advises otherwise. Avoid drinking alcohol while taking this medicine because it can increase the risk of stomach bleeding and liver strain. Do not start or stop any other medicine without informing your doctor, especially antibiotics, antifungals, or heart medicines. Keep a rescue inhaler with you at all times for sudden breathing difficulty. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Do not take more than the prescribed dose, as Theophylline can be toxic in higher amounts. Regular follow-up and blood tests may be needed to check drug levels and liver function.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to theophylline side effects due to reduced liver and kidney function. Lower doses and close monitoring are advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before conception. Theophylline may need dose adjustment during pregnancy. Montelukast should be used only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before any surgery. Theophylline can interact with anesthetic agents and may need to be temporarily stopped.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may interact with certain local anesthetics or sedatives.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Maintain a healthy weight to reduce breathing effort.
😴
Practice breathing exercises like pursed-lip breathing.
💧
Get vaccinated against influenza and pneumonia.
🧘
Use air purifiers if you live in polluted areas.
🌞
Stay hydrated to keep mucus thin.

🏋️ Exercise Considerations

Avoid strenuous exercise in cold or polluted air. Warm up gradually and use your rescue inhaler if prescribed before exercise. Stop immediately if you feel chest tightness or severe breathlessness.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit salt intake to reduce fluid retention.
Avoid foods that trigger allergies.
Stay well hydrated.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most desk jobs, but discuss with your doctor if your work involves physical exertion.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for advice on dose adjustment or alternative treatment.

📅 Long-Term Use Effects

Long-term use requires regular monitoring of theophylline blood levels, liver function, and heart rhythm. Prolonged use may lead to tolerance or toxicity if levels are not monitored. Do not stop suddenly without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled corticosteroids

First-line anti-inflammatory therapy for asthma.

Evidence: Well-established
Long-acting beta agonists

Used in combination with inhaled steroids for better control.

Evidence: Well-established
Pulmonary rehabilitation

Exercise and education program for COPD patients.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Annual influenza vaccination and pneumococcal vaccination are recommended for patients with chronic respiratory diseases. Discuss with your doctor about timing and suitability.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually in consultation with your doctor. Keep enough supply for the entire trip and carry it in your hand luggage. Check customs regulations for controlled substances in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with chronic asthma
He was prescribed this medicine as add-on therapy because his asthma was not controlled with inhalers alone. After 4 weeks, he noticed fewer night-time awakenings and less wheezing. He learned to take it with breakfast and avoid coffee to prevent tremors.
💡 Lesson: Consistent daily use and avoiding caffeine can improve tolerability and effectiveness.
👤 A 38-year-old woman with COPD
She started this medicine along with her regular inhalers. She experienced mild nausea initially, which resolved when she took it with food. Her breathing improved, and she could walk longer distances without stopping.
💡 Lesson: Taking the medicine with food reduces stomach upset and helps maintain adherence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Theophylline starts working within 30 minutes to 2 hours, while Montelukast takes a few days to weeks for full anti-inflammatory effects.

Q: Can I take it with other asthma medicines?

A: Yes, but only under your doctor's supervision. Some medicines can interact and increase side effects.

Q: Is it safe to take during pregnancy?

A: Consult your doctor. Theophylline crosses the placenta and may affect the baby. Your doctor will weigh the benefits and risks.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for telekast-t tablet cr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used to treat sudden asthma attacks.
    Fact: This medicine is for maintenance therapy only. It does not provide immediate relief during an acute attack. Always use a rescue inhaler for sudden symptoms.
  • Myth: Once symptoms improve, the medicine can be stopped.
    Fact: Do not stop this medicine without consulting your doctor. Stopping suddenly can worsen your condition.
  • Myth: It is safe to take extra doses if you feel breathless.
    Fact: Taking extra doses can lead to serious side effects, including seizures and heart problems. Follow your prescribed dose strictly.

🔄 Alternative Options

Generic Alternatives

  • Montelukast + Theophylline combination tablets from other manufacturers

Brand Alternatives

  • Telekast-T Tablet CR

📊 Comparison with Similar Medicines

[{"medicine":"Montelukast alone","difference":"Only anti-inflammatory; no bronchodilator effect."},{"medicine":"Theophylline alone","difference":"Only bronchodilator; no leukotriene blockade."},{"medicine":"Montelukast + Levocetirizine","difference":"Targets allergy symptoms more; less bronchodilation."}]

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