Beesol-BR Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or worsening breathlessness after taking the medicine
- Chest pain or tightness that does not go away
- Irregular or very fast heartbeat
- Swelling of the face, lips, tongue, or throat
- Severe headache with visual changes
- Muscle weakness or cramps with palpitations
- Blood in sputum or severe coughing fits
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is Synabron Forte 8mg/2mg/100mg Tablet used for?
This medicine is a combination of bromhexine (a mucolytic) and salbutamol (a bronchodilator) used to relieve productive cough with thick mucus and mild bronchospasm. It is taken orally, usually two to three times daily, and should be used only under medical supervision.
- Generic Name: Bromhexine (8mg) + Salbutamol (2mg)
- Manufacturer: Concept Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Synabron Forte 8mg/2mg/100mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमहेक्सिन और सालबुटामोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी, छाती में जकड़न और सांस लेने में कठिनाई में राहत के लिए किया जाता है। ब्रोमहेक्सिन गाढ़े बलगम को पतला करता है जिससे खांसी में आसानी होती है, और सालबुटामोल सांस की नलियों को फैलाकर सांस लेने में मदद करता है। यह दवा ब्रोंकाइटिस, अस्थमा और सीओपीडी जैसी स्थितियों में डॉक्टर की सलाह पर दी जाती है। सूखी खांसी के लिए इसका उपयोग न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में जी मिचलाना, पेट में असहजता, सिरदर्द, चक्कर आना, हाथों में कंपन, बेचैनी और दिल की धड़कन बढ़ना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। गंभीर दुष्प्रभावों में तेज़ धड़कन, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और पोटैशियम की कमी शामिल हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में दो से तीन बार भोजन के बाद। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। सूखी खांसी के लिए इसका इस्तेमाल न करें। अगर आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड, मिर्गी या गुर्दे/यकृत की बीमारी है तो डॉक्टर को पहले बताएं। इस दवा के साथ शराब न लें। चक्कर या कंपन महसूस होने पर वाहन न चलाएं। बच्चों से दूर, ठंडी और सूखी जगह पर रखें।
💊 Synabron Forte 8mg/2mg/100mg Tablet Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin bronchial secretions, making it easier to cough out mucus.","evidence":"Well-established for bromhexine component"},{"condition":"Acute bronchitis","description":"Relieves cough and mucus plugging while salbutamol eases associated bronchospasm.","evidence":"Commonly used; evidence moderate"},{"condition":"Chronic bronchitis","description":"Supports mucus clearance and provides short-term bronchodilation in chronic bronchitis flare-ups.","evidence":"Commonly used; evidence moderate"},{"condition":"Asthma with mucus hypersecretion","description":"Used as add-on symptomatic relief when asthma is accompanied by thick mucus and mild bronchospasm.","evidence":"Limited; not a controller therapy"},{"condition":"COPD with productive cough","description":"May help in mild COPD exacerbations with mucus retention, but not for severe attacks.","evidence":"Limited; specialist supervision advised"}]
Off-label uses: [{"condition":"Pre-operative airway clearance in selected patients","description":"Sometimes used to loosen secretions before surgery in patients with mucus retention, but evidence is limited.","evidence":"Limited"},{"condition":"Sinusitis with thick secretions","description":"Occasionally prescribed to thin nasal and sinus secretions, though not a standard indication.","evidence":"Limited"}]
Primary treatment for: Productive cough with bronchospasm
Also treats: Acute bronchitis, Chronic bronchitis, Asthma with mucus, COPD with mucus
📋 Drug Information
| Generic Name(s) | Bromhexine (8mg) + Salbutamol (2mg) |
| Brand Name | Synabron Forte 8mg/2mg/100mg Tablet |
| Manufacturer | Concept Pharmaceuticals Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a cool, dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | Typically 24 months from the date of manufacture. Refer to the packaging for the exact expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Bromhexine increases serous bronchial secretion and breaks down acidic mucopolysaccharide fibers in mucus, reducing its viscosity and making it easier to expel. Salbutamol selectively stimulates beta-2 adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP, which relaxes the muscles and widens the airways. The combination improves both mucus clearance and airflow.
Mechanism Steps
💡 How to Take Synabron Forte 8mg/2mg/100mg Tablet
Strength: Immediate-release oral tablet containing bromhexine 8 mg and salbutamol 2 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet two to three times a day, taken with or after meals. The exact dose and duration depend on the condition being treated, its severity, and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular and neurological effects of salbutamol. Use with caution and consider lower doses as advised by a clinician. Monitor heart rate, blood pressure, and potassium levels. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be required based on kidney function. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment due to extensive liver metabolism of bromhexine. Dose adjustment may be necessary. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended adult dose is usually three tablets per day (bromhexine 24 mg and salbutamol 6 mg). Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Synabron Forte 8mg/2mg/100mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Digoxin | Moderate | |
| Loop diuretics | Moderate | |
| Corticosteroids | Moderate | |
| Theophylline | Moderate | |
| Other sympathomimetics | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Non-selective beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
- Digoxin
- Diuretics (loop and thiazide)
⚡ Moderate Interactions
- Corticosteroids
- Xanthine derivatives (e.g., theophylline)
- Other sympathomimetics
- Anticholinergics (e.g., ipratropium)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can worsen dizziness, drowsiness, and cardiovascular effects such as increased heart rate and low blood pressure. It may also increase the risk of stomach upset.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to bromhexine, salbutamol, or any component of this medicine","Severe cardiovascular disease including severe heart failure and uncontrolled arrhythmias","Severe uncontrolled hypertension","Severe liver or kidney impairment","Acute severe asthma attack requiring emergency treatment","Use in children below the age recommended by a pediatrician"]
⚠️ Warnings & Precautions
["Do not use for a dry, non-productive cough.","Use with caution in patients with heart disease, high blood pressure, diabetes, thyroid disorders, or epilepsy.","May cause tremor, nervousness, and increased heart rate; avoid driving if affected.","Monitor potassium levels if used with diuretics or corticosteroids.","Do not exceed the prescribed dose or duration.","Consult a doctor if symptoms worsen or do not improve within a few days.","Avoid alcohol while taking this medicine.","Inform your doctor about all other medicines you are taking."]
🤱 Lactation Safety
Salbutamol is excreted in breast milk in small amounts. Bromhexine safety during breastfeeding is not well established. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe tachycardia, tremor, restlessness, chest pain, hypokalemia, and hypertension. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs, electrolytes, and cardiac rhythm. There is no specific antidote for this combination.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually two to three times a day for adults, and do not exceed the recommended dose. Swallow the tablet whole with a glass of water; do not crush or chew it. Avoid taking it close to bedtime if it causes nervousness or sleep disturbance. Do not use this medicine for a dry cough or for more than the duration advised by your clinician. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, epilepsy, or liver or kidney disease before starting this medicine. Avoid alcohol while taking it, as it can worsen dizziness and heart rate changes. Do not drive or operate heavy machinery if you feel dizzy or shaky. Keep out of reach of children and store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular and neurological effects of salbutamol, including increased heart rate, tremor, and dizziness. Use with caution, monitor vital signs, and consider lower doses as advised by a clinician. Check kidney and liver function before prolonged use.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks before prescribing it.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. Salbutamol can affect heart rate and blood pressure during anesthesia. Your doctor may advise stopping it temporarily or adjusting the dose.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth or increase heart rate during dental procedures. Local anesthetics containing adrenaline should be used with caution due to potential additive cardiovascular effects.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have an active cough or breathing difficulty. Light activity like walking is fine if you feel comfortable. If exercise triggers coughing or breathlessness, stop and rest. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tremor, or nervousness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue desk work, but take breaks and stay hydrated. Inform your employer if you need to take frequent breaks due to cough or breathing issues.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 5 to 7 days, if they worsen, or if you experience serious side effects such as palpitations, chest pain, severe dizziness, or allergic reactions. Do not stop a prescribed course without medical advice, especially if you have an underlying lung condition.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of salbutamol may lead to tolerance, increased heart rate, tremor, and reduced potassium levels. Bromhexine is generally well tolerated but long-term safety data are limited. Regular monitoring of heart rate, blood pressure, and electrolytes may be needed if used for extended periods. Do not use it continuously for more than the duration advised by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and ease breathing naturally.
Evidence: Traditionally used; limited clinical evidenceCan help clear nasal congestion and post-nasal drip.
Evidence: Moderate evidence for upper respiratory symptomsTechniques to help clear airway secretions in chronic lung conditions.
Evidence: Well-established for mucus clearanceSoothes the throat and may reduce cough frequency.
Evidence: Limited but supportive evidence💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you have an active infection with fever, consult your doctor before taking any vaccine. Preventive vaccinations such as influenza and pneumococcal vaccines are recommended for people with chronic lung diseases.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight during travel. If crossing time zones, continue your doses at regular intervals as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country. Keep enough supply for the entire trip and carry it in your hand luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The salbutamol component may start easing breathing within 15 to 30 minutes, while the bromhexine effect on mucus may take several hours to a few days of regular use.
A: No, this medicine is meant for productive cough with thick mucus. It is not effective for dry cough.
A: Some blood pressure medicines, especially beta-blockers, can interact with this medicine. Always inform your doctor about all medicines you take.
A: Complete the course as prescribed by your doctor. Do not stop abruptly without medical advice, especially if you have an underlying lung condition.
A: If you remember within half the dosing interval, take it. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for Synabron Forte 8mg/2mg/100mg Tablet
View AllAlternative brands with exact same active ingredient:
-
broxine 2mg/8mg tabletHealthy Life Pharma Pvt Ltd ₹1.88 84.9% CHEAPER
-
ventilate 2mg/8mg tabletMapra Laboratories Pvt Ltd ₹1.88 84.9% CHEAPER
-
bronchosol-br tabletTOSC International Pvt Ltd ₹5.63 54.9% CHEAPER
-
brolax tabletLancer Health Care Pvt Ltd ₹7.03 43.6% CHEAPER
-
Salumoxin SyrupDensa Pharmaceuticals Pvt Ltd ₹11.98 3.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: It is only for productive cough with mucus and bronchospasm, not for dry cough or infections requiring antibiotics. - Myth: More tablets mean faster relief.
Fact: Taking more than prescribed increases the risk of serious heart and nerve side effects without added benefit. - Myth: It is safe to take with any other medicine.
Fact: It can interact with beta-blockers, antidepressants, diuretics, and other drugs. Always inform your doctor about all medicines you take. - Myth: It can be used for a long time without supervision.
Fact: Prolonged use should be monitored by a doctor due to cardiovascular and metabolic effects.
🔄 Alternative Options
Generic Alternatives
- Bromhexine + Salbutamol tablet (generic)
Brand Alternatives
- Beesol-BR Tablet