Arimip 75mg Tablet SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Confusion, hallucinations, or agitation
- Seizures
- Suicidal thoughts or behavior
- Yellowing of skin or eyes
- Difficulty urinating
If experiencing severe symptoms, call emergency services immediately.
What is syconil 75mg tablet used for?
This medicine is a tricyclic antidepressant used to treat obsessive-compulsive disorder (OCD) and depression. It works by increasing serotonin and norepinephrine in the brain. It is available as a 75 mg sustained-release tablet and is taken orally, usually once daily. It requires a prescription and close medical supervision.
- Generic Name: Clomipramine (75mg)
- Manufacturer: Psycormedies
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 syconil 75mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोमिप्रामाइन नामक सक्रिय तत्व से बनी है, जिसका उपयोग मुख्य रूप से ऑब्सेसिव-कंपल्सिव डिसऑर्डर (OCD) और अवसाद के इलाज के लिए किया जाता है। यह मस्तिष्क में सेरोटोनिन और नॉरएपिनेफ्रिन के स्तर को बढ़ाकर काम करती है, जिससे मूड में सुधार होता है और बार-बार आने वाले विचारों और व्यवहारों को कम किया जा सकता है। यह दवा 75 मिलीग्राम की सस्टेन्ड-रिलीज़ गोली के रूप में उपलब्ध है और इसे मुँह से लिया जाता है। इसका उपयोग डॉक्टर की सलाह के बिना नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, नींद आना, चक्कर आना, कब्ज, धुंधली दृष्टि और वजन बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, सेरोटोनिन सिंड्रोम, दौरे और आत्मघाती विचार शामिल हो सकते हैं। यदि आपको कोई भी गंभीर लक्षण दिखाई दे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, विशेष रूप से हृदय रोग, मिर्गी, ग्लूकोमा, थायरॉइड या गुर्दे/यकृत की बीमारी। इस दवा को अचानक बंद न करें, क्योंकि इससे withdrawal के लक्षण हो सकते हैं। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 syconil 75mg tablet Uses & Benefits
- [{"condition":"Obsessive-compulsive disorder (OCD)","description":"This medicine is effective in reducing the frequency and intensity of obsessive thoughts and compulsive behaviors.
- It is often used when SSRIs are not effective.","evidence":"Well-established"},{"condition":"Major depressive disorder","description":"This medicine can be used to treat depression, especially when other antidepressants have failed.
- It helps improve mood, sleep, and appetite.","evidence":"Well-established"},{"condition":"Panic disorder","description":"This medicine may help reduce the frequency and severity of panic attacks.","evidence":"Moderate"},{"condition":"Chronic pain syndromes","description":"This medicine is sometimes used to manage neuropathic pain and other chronic pain conditions.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Premature ejaculation","description":"This medicine may be prescribed off-label to delay ejaculation, but it is not approved for this use.","evidence":"Limited"},{"condition":"Cataplexy","description":"This medicine has been used off-label to reduce cataplexy attacks in narcolepsy.","evidence":"Limited"}]
Primary treatment for: Obsessive-compulsive disorder (OCD)
Also treats: Major depressive disorder, Panic disorder, Chronic pain syndromes
📋 Drug Information
| Generic Name(s) | Clomipramine (75mg) |
| Brand Name | syconil 75mg tablet |
| Manufacturer | Psycormedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Tricyclic antidepressants |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the reuptake of serotonin and norepinephrine in the brain. This increases the availability of these neurotransmitters in the synaptic cleft, which helps to regulate mood and reduce obsessive thoughts. It also has effects on other receptors, such as histamine and muscarinic receptors, which contribute to its side effect profile.
Mechanism Steps
💡 How to Take syconil 75mg tablet
Strength: Sustained-release tablet, 75 mg
Dosage Information
| Adult Dosage | The usual starting dose for adults is 25 mg once daily, gradually increased over 1-2 weeks to a target dose of 75-150 mg daily, depending on the condition being treated and your response. The maximum recommended daily dose is 250 mg, but doses above 150 mg should be used with caution. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose (e.g., 10-25 mg daily) and increase gradually. Close monitoring for side effects is recommended. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | 250 mg per day (but doses above 150 mg should be used with caution). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of syconil 75mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| CYP2D6 inhibitors | Moderate | |
| CNS depressants | Moderate | |
| Anticholinergics | Minor |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- SSRIs (e.g., fluoxetine, sertraline)
- Other tricyclic antidepressants
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., quinidine, fluoxetine)
- CNS depressants (e.g., alcohol, benzodiazepines)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and impair your ability to drive or operate machinery. It may also worsen depression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clomipramine or other tricyclic antidepressants","Concurrent use with MAO inhibitors","Acute recovery phase after myocardial infarction","Uncontrolled glaucoma","Severe liver disease"]
⚠️ Warnings & Precautions
["May increase risk of suicidal thoughts and behaviors, especially in young adults. Close monitoring is required.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","May impair ability to drive or operate machinery. Avoid until you know how it affects you.","Use with caution in patients with epilepsy, as it may lower seizure threshold.","May cause orthostatic hypotension; rise slowly from sitting or lying positions."]
🤱 Lactation Safety
This medicine passes into breast milk. Consult your doctor before breastfeeding. Monitoring of the infant for sedation and feeding difficulties is recommended.
💊 Overdose Management
Overdose of this medicine can be life-threatening. Symptoms include irregular heartbeat, severe drowsiness, confusion, seizures, and coma. Seek emergency medical help immediately. Treatment is supportive and may include activated charcoal, gastric lavage, and management of cardiac arrhythmias.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before starting this medicine, inform your doctor about all your medical conditions, especially heart disease, epilepsy, glaucoma, thyroid problems, or liver/kidney disease. Do not stop taking this medicine abruptly, as it can cause withdrawal symptoms such as nausea, headache, and dizziness. Always follow your doctor's instructions for tapering the dose. Avoid alcohol while taking this medicine, as it can increase drowsiness and impair your ability to drive or operate machinery. This medicine can interact with many other drugs, including MAOIs, SSRIs, and certain pain relievers, so always check with your doctor or pharmacist before taking any new medication. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your doctor. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and cardiac effects. Lower starting doses and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Your doctor may consider switching to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rhythm. Your doctor may advise temporary discontinuation before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it can cause dry mouth and may interact with certain dental anesthetics. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and impair concentration, affecting your ability to drive or operate machinery. It may also affect your work performance initially. Discuss with your doctor about timing the dose to minimize impact.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or need to discontinue, your doctor will guide you on a gradual taper to avoid withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of heart function, liver function, and blood counts. It can cause weight gain and sexual dysfunction. Periodic evaluation by your doctor is recommended to assess the continued need and adjust the dose.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
CBT is effective for OCD and depression and can be used alongside or instead of medication.
Evidence: Well-establishedSSRIs are often first-line for OCD and depression with a different side effect profile.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually in consultation with your doctor. Check local customs regulations regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may take 2-4 weeks to notice initial improvements, with full benefits often taking up to 10-12 weeks.
A: No, do not stop abruptly. Consult your doctor for a gradual taper to avoid withdrawal symptoms.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for syconil 75mg tablet
View AllAlternative brands with exact same active ingredient:
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depramine 75mg tabletRKG Pharma ₹32.81 66.7% CHEAPER
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imi-ci 75mg tabletSunrise Remedies Pvt Ltd ₹82.03 16.8% CHEAPER
-
obnil 75mg tabletA N Pharmacia ₹85.48 13.3% CHEAPER
-
clom 75mg tablet srOrchid Chemicals & Pharmaceuticals Ltd ₹88.13 10.6% CHEAPER
-
clomistar 75mg tablet srGentech Healthcare Pvt Ltd ₹100.50 1.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: This medicine is not considered addictive, but it can cause dependence and withdrawal symptoms if stopped abruptly. It should be tapered gradually under medical supervision. - Myth: This medicine works immediately.
Fact: It may take several weeks to see the full benefits of this medicine. It is important to continue taking it as prescribed.
🔄 Alternative Options
Generic Alternatives
- Clomipramine 75 mg sustained-release tablet
Brand Alternatives
- Anafranil
- Clomipramine 75 mg SR