Depramine 75mg Tablet

4.6 (11 reviews)

Clomipramine (75mg)

🏭 RKG Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is depramine 75mg tablet used for?

Depramine 75mg Tablet contains Clomipramine, a tricyclic antidepressant used primarily to treat depression and obsessive-compulsive disorder (OCD). It works by restoring the balance of certain natural substances (serotonin and norepinephrine) in the brain, helping to improve mood and reduce anxiety.

Generic Name: Clomipramine (75mg)
Manufacturer: RKG Pharma
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 depramine 75mg tablet Uses & Benefits

Detailed medical information is being added to our database.

📋 Drug Information

Generic Name(s)	Clomipramine (75mg)
Brand Name	depramine 75mg tablet
Manufacturer	RKG Pharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Tricyclic antidepressants
Route of Administration	Oral
Storage	Room temperature (15-30°C), away from moisture
Shelf Life	As per manufacturer

💡 How to Take depramine 75mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of depramine 75mg tablet

✅ Common Side Effects

Dry mouth
Drowsiness
Dizziness
Constipation
Blurred vision

🚨 Serious Side Effects

Chest pain or irregular heartbeat
Seizures
Severe dizziness or fainting
Signs of serotonin syndrome (e.g., fever, muscle stiffness, confusion)

⚠️ Rare Side Effects

Yellowing of skin or eyes (jaundice)
Unusual bleeding or bruising
Severe allergic reaction (rash, itching, swelling)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Increased risk of serotonin syndrome
CNS depressants	Moderate	Enhanced sedative effects
Anticholinergics	Moderate	Increased anticholinergic side effects

🚨 Major Interactions

MAOIs (e.g., phenelzine, selegiline)
Other serotonergic drugs (e.g., SSRIs, SNRIs)
CNS depressants (e.g., alcohol, benzodiazepines)

⚡ Moderate Interactions

Anticholinergic drugs (e.g., atropine, antihistamines)
Blood pressure medications (e.g., guanethidine)
Warfarin

ℹ️ Minor Interactions

Cimetidine
Oral contraceptives
Smoking (may decrease drug levels)

🍽️ Food Interactions

Depramine can be taken with or without food. However, grapefruit juice may increase the risk of side effects and should be avoided. A high-fiber diet may help with constipation.

🍷 Alcohol Interaction

Alcohol can increase the central nervous system depressant effects of Depramine, leading to severe drowsiness, dizziness, and impaired coordination. It is best to avoid alcohol while taking this medication.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

High

🚫 Contraindications

Depramine is contraindicated in patients with recent myocardial infarction, severe liver disease, narrow-angle glaucoma, or known hypersensitivity to tricyclic antidepressants. It should not be used concurrently with MAOIs or within 14 days of stopping them.

⚠️ Warnings & Precautions

Depramine should be used with caution in patients with a history of seizures, heart disease (especially arrhythmias), glaucoma, urinary retention, or hyperthyroidism. It may increase the risk of suicidal thoughts in young adults. Regular monitoring of liver function, ECG, and blood counts is recommended. Avoid abrupt discontinuation to prevent withdrawal symptoms.

💊 Overdose Management

In case of overdose, seek emergency medical attention immediately. Symptoms may include severe drowsiness, confusion, hallucinations, fast or irregular heartbeat, seizures, and coma. Treatment is supportive and may include gastric lavage and activated charcoal.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for a missed one.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for depramine 75mg tablet

View All

Alternative brands with exact same active ingredient (Clomipramine (75mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.