Parcaff 50mg/500mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
- Blood in vomit or black, tarry stools
- Swelling of the face, lips, or throat, or difficulty breathing
- Fast, irregular, or pounding heartbeat that does not settle
- Severe headache with confusion, weakness, or vision changes
- Signs of severe allergic reaction such as spreading rash or blisters
- Decreased urine output or swelling of the legs
If experiencing severe symptoms, call emergency services immediately.
What is stopache tablet used for?
This medicine is a combination of caffeine 50 mg and paracetamol 500 mg used for short-term relief of mild to moderate pain such as headache, dental pain, and menstrual cramps. It works by reducing pain and fever through paracetamol, while caffeine enhances the pain-relieving effect. It should be taken only as advised by a doctor and not for prolonged periods without review.
- Generic Name: Caffeine (50mg) + Paracetamol (500mg)
- Manufacturer: Paras Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 stopache tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैफीन 50 मिलीग्राम और पैरासिटामोल 500 मिलीग्राम का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार में राहत के लिए किया जाता है। यह सिरदर्द, माइग्रेन, दांत दर्द, मासिक धर्म के दर्द और मांसपेशियों के दर्द में मदद करती है। पैरासिटामोल दर्द और बुखार को कम करता है, जबकि कैफीन दर्द निवारक प्रभाव को बढ़ाता है। इस दवा को डॉक्टर की सलाह के अनुसार ही लें और लंबे समय तक बिना सलाह इस्तेमाल न करें।
साइड इफेक्ट्स: इस दवा को सही मात्रा में लेने पर आमतौर पर हल्के दुष्प्रभाव ही होते हैं। कुछ लोगों को मतली, पेट में असहजता, बेचैनी, नींद न आना, घबराहट या दिल की धड़कन तेज होना महसूस हो सकता है, जो अक्सर कैफीन के कारण होता है। बहुत कम लोगों में त्वचा पर गंभीर रैश, पीलिया, गहरे रंग का पेशाब या सूजन जैसी गंभीर समस्या हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर या फार्मासिस्ट की बताई गई मात्रा और समय के अनुसार ही लें। एक दिन में तय मात्रा से ज्यादा न लें और बिना सलाह लंबे समय तक इस्तेमाल न करें। इस दवा के साथ शराब न पिएं क्योंकि इससे लिवर को नुकसान का खतरा बढ़ सकता है। सर्दी-जुकाम की दवाओं में भी पैरासिटामोल हो सकता है, इसलिए दूसरी दवाएं लेने से पहले लेबल जरूर पढ़ें। अगर आपको लिवर या किडनी की बीमारी है, आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।
💊 stopache tablet Uses & Benefits
[{"condition":"Tension-type headache","description":"Provides short-term relief of mild to moderate tension headache pain, with caffeine enhancing the analgesic effect of paracetamol.","evidence":"Well-established"},{"condition":"Migraine headache","description":"Used for acute relief of migraine attacks in adults; caffeine may improve pain relief when combined with paracetamol.","evidence":"Well-established"},{"condition":"Dental pain","description":"Helps relieve mild to moderate toothache and post-dental procedure pain as a short-term measure.","evidence":"Moderate"},{"condition":"Menstrual cramps","description":"Provides relief from primary dysmenorrhea pain in some women when used as directed.","evidence":"Moderate"},{"condition":"Musculoskeletal pain","description":"Used for short-term relief of mild to moderate muscle and joint pain, such as strains and sprains.","evidence":"Moderate"},{"condition":"Fever","description":"Paracetamol reduces fever, although this combination is primarily marketed for pain relief.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used as part of multimodal analgesia after minor surgery, but only under medical supervision.","evidence":"Limited"},{"condition":"Caffeine withdrawal headache","description":"May be used short-term to relieve headache associated with caffeine withdrawal, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Mild to moderate pain and fever
Also treats: Tension headache, Migraine, Dental pain, Menstrual cramps, Musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Caffeine (50mg) + Paracetamol (500mg) |
| Brand Name | stopache tablet |
| Manufacturer | Paras Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store below 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container or blister pack. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Paracetamol reduces pain and fever mainly by acting on the central nervous system, where it inhibits prostaglandin synthesis and modulates pain perception. Caffeine is a methylxanthine that blocks adenosine receptors, which leads to vasoconstriction of cerebral blood vessels and enhanced release of certain neurotransmitters. When combined, caffeine increases the analgesic effect of paracetamol, which is why this combination can be more effective for headache than paracetamol alone.
Mechanism Steps
💡 How to Take stopache tablet
Strength: Tablet containing caffeine 50 mg and paracetamol 500 mg, immediate release.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 4 to 6 hours as needed for pain or fever, but the exact dose and frequency depend on the indication, the patient's liver and kidney function, and other medicines being taken. Do not exceed the maximum recommended daily dose of paracetamol, and do not take this medicine for more than a few days without medical advice. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the effects of caffeine and may have reduced liver or kidney function. Use the lowest effective dose for the shortest necessary time, and consult a doctor if you have liver, kidney, or heart problems. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose adjustment may be needed, and this medicine should be used only under medical supervision in people with significant kidney disease. |
| Hepatic Impairment | Use with caution in patients with liver impairment. The dose may need to be reduced or the medicine avoided in severe liver disease. Consult a doctor before use. |
| Maximum Daily Dose | The maximum daily dose of paracetamol from all sources should not exceed 4000 mg in adults, and many clinicians recommend a lower limit of 3000 mg per day for safer use. Do not exceed the dose advised by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of stopache tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other paracetamol products | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Fluvoxamine | Moderate | |
| Ciprofloxacin | Moderate | |
| Oral contraceptives | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Warfarin
- Other paracetamol-containing products
- Alcohol
⚡ Moderate Interactions
- Carbamazepine, phenytoin, rifampicin
- Fluvoxamine
- Ciprofloxacin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Regular or heavy alcohol use increases the risk of paracetamol-related liver damage, and alcohol can also add to the stimulant effects of caffeine, causing palpitations and sleep problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to paracetamol, caffeine, or any component of this medicine","Severe liver disease or active liver failure","Severe kidney impairment without medical supervision","Use of other paracetamol-containing medicines without medical advice","Regular heavy alcohol use without medical advice"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of paracetamol, as overdose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Check other medicines for paracetamol content to avoid accidental overdose.","Use with caution in people with liver or kidney disease.","Caffeine may cause restlessness, insomnia, and palpitations; limit other caffeine sources.","Consult a doctor before use during pregnancy or breastfeeding.","Do not use for longer than the recommended period without medical review.","Keep out of reach of children."]
🤱 Lactation Safety
Paracetamol is considered compatible with breastfeeding when used at recommended doses. Caffeine passes into breast milk in small amounts, and occasional use is usually acceptable, but regular or high intake may cause irritability or poor sleep in the infant. Consult your doctor before using this combination while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause serious liver damage due to paracetamol, and caffeine overdose can cause agitation, palpitations, and seizures. If you suspect an overdose, seek emergency medical care immediately, even if you feel well. Do not wait for symptoms to appear. Treatment may include activated charcoal, N-acetylcysteine, and supportive care, and it should be started as early as possible.
⏰ Missed Dose
This medicine is usually taken only when needed for pain or fever, so a missed-dose schedule may not apply. If you are on a scheduled regimen and miss a dose, take it as soon as you remember, unless it is almost time for the next dose. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always follow the dose and duration advised by your doctor or pharmacist. Do not take more than the recommended dose, and do not use this medicine for longer than the period advised without medical review. Avoid drinking alcohol while taking this medicine because alcohol can increase the risk of liver damage from paracetamol. Check the labels of other medicines you take, such as cold and flu remedies, because many of them also contain paracetamol, and taking them together can lead to an accidental overdose. If you have liver or kidney problems, a history of alcohol use disorder, or you are pregnant or breastfeeding, speak to your doctor before using this medicine. Keep this medicine out of the reach of children, and store it in its original packaging away from heat and moisture. If your pain or fever does not improve within a few days, or if it gets worse, consult a qualified clinician rather than continuing to self-medicate.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to caffeine and may have reduced liver or kidney function. Use the lowest effective dose for the shortest time, and consult a doctor if you have heart, liver, or kidney problems or take other medicines.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive or are pregnant, consult your doctor before using this medicine. Paracetamol is generally preferred for pain and fever in pregnancy when needed, but caffeine intake should be limited. Do not self-medicate.
🏥 Post-Surgery Considerations
After surgery, pain relief should be managed by your surgical team. Do not self-medicate with this combination without asking your doctor, because other medicines may already contain paracetamol.
🦷 Dental Procedures
This medicine can provide short-term relief for dental pain, but it does not treat the underlying dental problem. Inform your dentist about all medicines you take before any dental procedure, and follow their advice on pain relief.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine usually does not restrict exercise, but if you feel dizzy, restless, or have palpitations, avoid strenuous activity until you feel better. If you are being treated for an injury, follow your doctor's advice on activity.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild restlessness or palpitations in some people due to caffeine. Most people can continue their usual activities, but avoid driving or operating heavy machinery if you feel dizzy, jittery, or unwell.
🛑 When to Stop This Medicine
Stop this medicine when your pain or fever has resolved, or as advised by your doctor. Do not stop a prescribed course without consulting your doctor. Seek medical advice if symptoms return or worsen after stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged high-dose paracetamol can increase the risk of liver and kidney problems, and regular caffeine intake can lead to dependence, sleep disturbance, and palpitations. If you need pain relief for more than a few days, consult a doctor to find the underlying cause and a safer long-term plan.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Adequate rest and fluids can help relieve tension headaches and mild pain.
Evidence: Well-establishedCan help with musculoskeletal pain and reduce the need for painkillers.
Evidence: Well-establishedStress management can reduce the frequency of tension headaches.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not generally interfere with vaccines. If you have a fever, your doctor may advise delaying vaccination until you feel better. Follow your doctor's advice regarding vaccination timing.
📦 Storage Guide
✅ DO
Store below 30°C in a dry place
❌ DON'T
Do not store in a hot or humid place such as a bathroom
✅ DO
Keep in the original container or blister pack
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not leave in a car or near a heat source
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription or a copy of it, especially when travelling internationally. Keep it in your hand luggage so it stays at a suitable temperature and is accessible if needed. Avoid leaving it in a hot car or in direct sunlight. If you are crossing time zones and take this medicine on a schedule, ask your doctor how to adjust the timing. Check the customs rules of your destination for carrying medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief usually starts within 30 to 60 minutes after taking the tablet.
A: The effect typically lasts about 4 to 6 hours.
A: No. Alcohol increases the risk of liver damage from paracetamol and should be avoided.
A: It is intended for short-term use. Long-term use should only be done under medical supervision.
A: Paracetamol is generally preferred in pregnancy when needed, but caffeine should be limited. Consult your doctor before using this combination.
A: The total paracetamol from all sources should not exceed 4000 mg per day in adults, and many doctors recommend a lower limit. Follow your doctor's advice.
🤔 Common Patient Concerns
🔄 Substitutes for stopache tablet
View AllAlternative brands with exact same active ingredient:
-
abalgin tabletVostok & Wilcure Remedies ₹8.44 48.7% CHEAPER
-
action 50mg/500mg tabletFlora & Pharma ₹9.38 43% CHEAPER
-
anacin tabletPfizer Ltd ₹21.09 28.1% COSTLIER
-
parcaff 50mg/500mg tabletBiochem Pharmaceutical Industries ₹22.03 33.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is completely safe at any dose.
Fact: Paracetamol can cause serious liver damage if taken in overdose or at high doses for a long time. - Myth: It is fine to take this medicine with alcohol.
Fact: Alcohol increases the risk of liver damage from paracetamol and should be avoided. - Myth: More tablets mean faster pain relief.
Fact: Taking more than the recommended dose does not improve relief and can be dangerous. - Myth: This medicine can be taken indefinitely for chronic pain.
Fact: It is intended for short-term use unless a doctor advises otherwise.
🔄 Alternative Options
Generic Alternatives
- Caffeine 50 mg + Paracetamol 500 mg tablet
- Paracetamol 500 mg tablet with caffeine 50 mg
Brand Alternatives
- Parcaff 50mg/500mg tablet