abalgin tablet - Uses, Price, Side Effects & Substitutes
What is abalgin tablet used for?
Alergin Cold Total Tablet (Paracetamol + Caffeine) is used to treat RESPIRATORY. It contains Paracetamol (500mg) + Caffeine (50mg), which Paracetamol inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin syn. Always consult your doctor before use. Take as prescribed.
- Generic Name: Paracetamol + Caffeine
- Manufacturer: Vostok & Wilcure Remedies
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ abalgin tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Paracetamol + Caffeine |
| Brand Name | Alergin Cold Total Tablet |
| Manufacturer | Vostok & Wilcure Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Analgesic Antipyretic Combination |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Paracetamol inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Caffeine is a CNS stimulant that blocks adenosine receptors.
Mechanism Steps
๐ก How to Take abalgin tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of abalgin tablet
โ Common Side Effects
- Nausea
- Vomiting
- Insomnia
- Nervousness
- Dizziness
๐จ Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- Anaphylaxis
- Seizures (caffeine overdose)
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk with high doses of paracetamol. |
| Alcohol | Major | Increased hepatotoxicity risk with chronic heavy alcohol use. |
| Isoniazid | Major | Increased risk of hepatotoxicity. |
| Rifampin | Major | Reduced paracetamol efficacy and increased hepatotoxicity. |
| Oral contraceptives | Moderate | Reduced caffeine clearance. |
| Cimetidine | Moderate | Increased caffeine levels. |
| Disulfiram | Moderate | Reduced caffeine clearance. |
| Fluvoxamine | Moderate | Increased caffeine levels. |
| Theophylline | Minor | Additive CNS stimulation. |
| Phenytoin | Minor | Reduced paracetamol efficacy. |
| Carbamazepine | Minor | Reduced paracetamol efficacy. |
๐จ Major Interactions
- Warfarin
- Alcohol (chronic heavy use)
- Isoniazid
- Rifampin
โก Moderate Interactions
- Oral contraceptives
- Cimetidine
- Disulfiram
- Fluvoxamine
โน๏ธ Minor Interactions
- Theophylline
- Phenytoin
- Carbamazepine
๐ฝ๏ธ Food Interactions
Avoid excessive caffeine-containing foods/beverages; food may delay absorption.
๐ท Alcohol Interaction
Chronic heavy alcohol use increases hepatotoxicity risk; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe hepatic impairment, hypersensitivity to any component, concurrent use of MAOIs.
๐ Monitoring Parameters
Liver function tests with prolonged use, renal function in high doses.
๐คฑ Lactation Safety
Paracetamol is safe; caffeine excreted in milk, limit intake.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for caffeine toxicity.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.