spasmonova tablet - Paracetamol (325mg) + Pamabrom (25mg) medicine

Pamaspas Tablet: Complete Information

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🏭 Macleods Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for Paracetamol; limited for Pamabrom.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is spasmonova tablet used for?

This medicine is a combination of Paracetamol and Pamabrom used to relieve PMS symptoms like bloating, headache, and minor aches. It works by reducing pain and increasing urine output.

  • Generic Name: Paracetamol (325mg) + Pamabrom (25mg)
  • Manufacturer: Macleods Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 spasmonova tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पीएमएस (प्रीमेंस्ट्रुअल सिंड्रोम) के लक्षणों जैसे सूजन, सिरदर्द, और हल्के दर्द को कम करने के लिए उपयोग की जाती है। यह पैरासिटामोल और पैमाब्रोम का संयोजन है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट की खराबी, सिरदर्द, चक्कर आना और पेशाब में वृद्धि शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लीवर या किडनी की समस्या हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब से बचें। यदि आपको लीवर या किडनी की बीमारी है तो डॉक्टर को बताएं। 10 दिनों से अधिक उपयोग न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 spasmonova tablet Uses & Benefits

[{"condition":"Premenstrual syndrome (PMS)","description":"Relieves bloating, water retention, headache, and minor aches associated with PMS.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Provides relief from mild to moderate menstrual pain.","evidence":"Well-established"},{"condition":"Water retention","description":"Helps reduce temporary water weight gain due to PMS.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Edema due to other causes","description":"Sometimes used off-label for mild edema, but not recommended without medical supervision.","evidence":"Limited"}]

Primary treatment for: Premenstrual syndrome

Also treats: Menstrual cramps, Water retention

📋 Drug Information

Generic Name(s)Paracetamol (325mg) + Pamabrom (25mg)
Brand Namespasmonova tablet
ManufacturerMacleods Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from moisture and heat.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 10 days.
6
Report any unusual bleeding or bruising immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bloating
This medicine is commonly prescribed for this.
Likely Use
✅
Headache
This medicine can help relieve headaches associated with PMS.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and completely absorbed from the gastrointestinal tract. Pamabrom is also absorbed from the gastrointestinal tract. Not established from the available information for specific rates.
DistributionParacetamol distributes widely into body tissues. Pamabrom distribution is not well established.
Protein BindingParacetamol: Approximately 10-25% bound to plasma proteins. Pamabrom: Not established from the available information.
MetabolismParacetamol is metabolized in the liver via conjugation with glucuronic acid and sulfate, and a small amount via CYP2E1 to N-acetyl-p-benzoquinone imine (NAPQI). Pamabrom metabolism is not well established.
Half-LifeParacetamol: 2-3 hours. Pamabrom: Not established from the available information.
ExcretionParacetamol is excreted in urine as metabolites. Pamabrom is excreted in urine.
BioavailabilityParacetamol: 80-100%. Pamabrom: Not established from the available information.
Onset of ActionParacetamol: 30-60 minutes. Pamabrom: Diuretic effect within 1-2 hours.
Peak Plasma TimeParacetamol: 0.5-2 hours. Pamabrom: Not established from the available information.
Duration of ActionParacetamol: 4-6 hours. Pamabrom: 4-6 hours.

How It Works

Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. Pamabrom is a xanthine derivative that acts as a mild diuretic by increasing renal blood flow and inhibiting tubular reabsorption of sodium and water, leading to increased urine output.

Mechanism Steps

1
Paracetamol action: Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing pain perception and fever.
2
Pamabrom action: Pamabrom increases renal blood flow and inhibits sodium and water reabsorption in the kidneys, promoting diuresis.

💡 How to Take spasmonova tablet

Strength: Tablet: Paracetamol 325 mg + Pamabrom 25 mg

1Take with a full glass of water.
2Take with food to reduce stomach upset.
3Do not crush or chew the tablet.
4Follow the prescribed schedule.

Dosage Information

Adult DosageThe usual adult dose is 1 to 2 tablets every 4 to 6 hours as needed, not to exceed 8 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageUse with caution. Dose may need adjustment based on renal and hepatic function. Consult doctor.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be necessary. Consult doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be necessary. Consult doctor.
Maximum Daily DoseParacetamol: 3250 mg (10 tablets) per day. Pamabrom: 200 mg (8 tablets) per day. Do not exceed 8 tablets in 24 hours.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of spasmonova tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Increased urination (Common (5-10%))
Stay hydrated. Consult doctor if excessive.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.

⚠️ Rare Side Effects

Blood disorders
Consult doctor if you experience unusual bleeding or bruising.
Kidney problems
Consult doctor if you experience decreased urine output or swelling.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Loop diuretics Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Carbamazepine
  • Loop diuretics

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it can increase the risk of liver damage, especially with Paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Paracetamol or Pamabrom","Severe liver disease","Severe kidney disease","Children under 12 years"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid alcohol.","Consult doctor if symptoms persist beyond 10 days.","Use with caution in elderly.","Inform doctor of all medications."]

🤱 Lactation Safety

Paracetamol is considered safe during breastfeeding. Pamabrom safety is not established. Consult your doctor.

💊 Overdose Management

Seek immediate medical attention. Overdose can cause severe liver damage. Treatment includes activated charcoal, N-acetylcysteine, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose. Avoid alcohol while taking this medicine as it can increase the risk of liver damage. Inform your doctor if you have a history of liver or kidney disease, or if you are taking blood thinners. Do not use this medicine for more than 10 days without consulting a doctor. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the diuretic effects and should use with caution. Dose adjustment may be needed.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Paracetamol is generally considered safe, but Pamabrom safety is not established.

🏥 Post-Surgery Considerations

Consult your doctor before use after surgery, especially if you are taking other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

No specific exercise restrictions, but stay hydrated if engaging in strenuous activities due to diuretic effect.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness or increased urination, which could affect driving or operating machinery. Use caution until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if symptoms persist beyond 10 days or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Paracetamol can lead to liver damage, and Pamabrom may cause electrolyte imbalances. Regular monitoring of liver and kidney function may be required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Dietary changes

Reducing salt intake can help with water retention.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 28-year-old woman with PMS symptoms
She experienced bloating and headaches before her periods. Her doctor prescribed this medicine. She took it as directed and noticed significant relief within a few hours. She emphasized taking it with food to avoid nausea.
💡 Lesson: Taking this medicine with food improves tolerability and provides effective relief from PMS symptoms.
👤 A 35-year-old woman with menstrual cramps
She used this medicine for menstrual cramps and water retention. It helped reduce pain and bloating. She was advised not to exceed the recommended dose and to avoid alcohol.
💡 Lesson: Adhering to the prescribed dose and avoiding alcohol ensures safety and efficacy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Paracetamol starts working within 30-60 minutes, while Pamabrom's diuretic effect begins within 1-2 hours.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for spasmonova tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It can be taken for any type of pain.
    Fact: It is specifically for PMS-related symptoms and should not be used for other types of pain without medical advice.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases the risk of liver damage and should be avoided.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol + Pamabrom combination tablets

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Paracetamol 325 mg + Pamabrom 25 mg","uses":"PMS symptoms"},{"medicine":"Paracetamol alone","composition":"Paracetamol 500 mg","uses":"Pain and fever"}]

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