adcospas tablet - Paracetamol (325mg) + Pamabrom (25mg) medicine

adcospas tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Oaknet Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is adcospas tablet used for?

Adcospas Tablet (Paracetamol + Pamabrom) is used to treat GASTRO INTESTINAL. It contains Paracetamol (325mg) + Pamabrom (25mg), which Paracetamol: Inhibits COX enzymes in CNS, reducing prostaglandin synthesis; Pama. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paracetamol + Pamabrom
  • Manufacturer: Oaknet Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š adcospas tablet Uses & Benefits

Relief of pain and fever associated with dysmenorrhea, headache, musculoskeletal pain.

Off-label uses: Premenstrual syndrome (PMS) symptoms

๐Ÿ“‹ Drug Information

Generic Name(s)Paracetamol + Pamabrom
Brand NameAdcospas Tablet
ManufacturerOaknet Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAnalgesic, Antipyretic, Diuretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionWidely distributed throughout body fluids.
Protein BindingParacetamol: 10-25%; Pamabrom: not well characterized.
MetabolismParacetamol: Hepatic via conjugation; Pamabrom: Hepatic.
Half-LifeParacetamol: 1.5-3 hours; Pamabrom: approximately 6 hours.
ExcretionParacetamol: Renal (primarily as conjugates); Pamabrom: Renal.
BioavailabilityParacetamol: 85-90%; Pamabrom: not well characterized.
Onset of ActionParacetamol: 30-60 minutes; Pamabrom: 1-2 hours.
Peak Plasma TimeParacetamol: 0.5-2 hours; Pamabrom: 2-4 hours.
Duration of ActionParacetamol: 4-6 hours; Pamabrom: 6-8 hours.

How It Works

Paracetamol: Inhibits COX enzymes in CNS, reducing prostaglandin synthesis; Pamabrom: Mild diuretic by inhibiting renal tubular reabsorption.

Mechanism Steps

1Paracetamol inhibits cyclooxygenase (COX) enzymes in the central nervous system, reducing prostaglandin synthesis.
2Pamabrom acts as a mild diuretic by inhibiting sodium and water reabsorption in the renal tubules.
3Combined effect provides relief from pain, fever, and fluid retention.

๐Ÿ’ก How to Take adcospas tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of adcospas tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk with high doses of paracetamol.
Alcohol Major Increased hepatotoxicity risk with chronic heavy use.
Isoniazid Major Increased risk of hepatotoxicity.
Carbamazepine Moderate Decreased paracetamol efficacy, increased hepatotoxicity.
Phenytoin Moderate Decreased paracetamol efficacy.
Barbiturates Moderate Decreased paracetamol efficacy.
Cholestyramine Minor Reduced absorption of paracetamol.
Oral contraceptives Minor Increased clearance of paracetamol.

๐Ÿšจ Major Interactions

  • Warfarin
  • Alcohol (chronic heavy use)
  • Isoniazid

โšก Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Barbiturates

โ„น๏ธ Minor Interactions

  • Cholestyramine
  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

High carbohydrate diet may delay absorption.

๐Ÿท Alcohol Interaction

Chronic heavy alcohol use increases risk of hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe hepatic impairment, hypersensitivity to any component.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, signs of bleeding.

๐Ÿคฑ Lactation Safety

Paracetamol is excreted in breast milk in low amounts; Pamabrom: unknown.

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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