Biospas 10 mg/40 mg Drop: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or stool
- Severe or worsening abdominal pain
- Persistent vomiting or inability to feed
- High fever with abdominal symptoms
- Swelling of the face, lips, or throat, or difficulty breathing
- Fast or irregular heartbeat
- Inability to pass urine
- Unusual drowsiness, confusion, or seizures
If experiencing severe symptoms, call emergency services immediately.
What is spasmokay drop used for?
This medicine is a combination of dicyclomine and dimethicone used to relieve abdominal cramps and gas-related bloating. Dicyclomine relaxes intestinal muscles, while dimethicone helps trapped gas pass more easily. It is commonly used in infants and children for colic, but must be given only under a doctor's guidance.
- Generic Name: Dicyclomine (10mg) + Dimethicone (40mg)
- Manufacturer: Khandelwal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 spasmokay drop के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और डाइमेथिकोन का संयोजन है, जिसका उपयोग पेट में ऐंठन, गैस, सूजन और शिशुओं के पेट दर्द (कोलिक) में राहत के लिए किया जाता है। डाइसाइक्लोमिन आंतों की मांसपेशियों को आराम देता है, जिससे ऐंठन कम होती है, और डाइमेथिकोन पेट में फंसी गैस के बुलबुले को छोटे-छोटे टुकड़ों में बदलकर बाहर निकलने में मदद करता है। यह दवा खासकर छोटे बच्चों में पेट दर्द और गैस की समस्या में दी जाती है, लेकिन इसे डॉक्टर की सलाह के बिना नहीं देना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मुंह सूखना, कब्ज, नींद आना, चक्कर आना, धुंधला दिखना और हल्का जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी दिल की धड़कन तेज होना, पेशाब करने में कठिनाई, भ्रम या चिड़चिड़ापन जैसी गंभीर समस्याएं हो सकती हैं। अगर बच्चा बहुत ज्यादा सुस्त हो जाए, दूध न पिए, या शरीर पर चकत्ते दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर की सलाह के अनुसार ही करें और हमेशा साथ दिए गए ड्रॉपर से सही मात्रा नापें। बिना डॉक्टर की सलाह के इसे लंबे समय तक न दें। बोतल को ठंडी और सूखी जगह पर रखें और बच्चों की पहुंच से दूर रखें। अगर बच्चे को ग्लूकोमा, पेशाब रोकने की समस्या या मायस्थेनिया ग्रेविस है, तो यह दवा न दें। दवा देने के बाद अगर आराम न मिले या नई समस्या दिखे, तो डॉक्टर से संपर्क करें।
💊 spasmokay drop Uses & Benefits
[{"condition":"Infantile colic and abdominal cramps","description":"This medicine helps relax intestinal smooth muscle and reduces trapped gas, which can ease crying and discomfort in infants with colic when prescribed by a pediatrician.","evidence":"Commonly used in clinical practice; evidence is supportive but not uniformly strong."},{"condition":"Gas-related abdominal bloating and flatulence","description":"Dimethicone in this medicine helps small gas bubbles combine into larger ones that are easier to pass, reducing bloating and pressure.","evidence":"Well-established for symptomatic relief of gas."},{"condition":"Spasmodic intestinal pain and irritable bowel-type cramps","description":"Dicyclomine reduces smooth muscle spasm in the gut, which can relieve cramping pain associated with functional bowel disorders.","evidence":"Established for short-term relief of spasmodic gastrointestinal pain."},{"condition":"Post-operative or procedure-related abdominal gas discomfort","description":"This medicine may be used to reduce gas-related discomfort after certain abdominal procedures, as advised by the treating doctor.","evidence":"Limited; used on a case-by-case basis."}]
Off-label uses: [{"condition":"Biliary or urinary tract spasm","description":"Dicyclomine may sometimes be used for smooth muscle spasm outside the gut, but this is not a standard approved use for the drop formulation.","evidence":"Limited"},{"condition":"Motion sickness-related abdominal discomfort","description":"Occasionally used for cramping discomfort during travel, but this is not a primary indication.","evidence":"Limited"}]
Primary treatment for: Infantile colic and gas-related abdominal discomfort
Also treats: Irritable bowel syndrome with cramping, Functional abdominal bloating, Post-operative gas discomfort
📋 Drug Information
| Generic Name(s) | Dicyclomine (10mg) + Dimethicone (40mg) |
| Brand Name | spasmokay drop |
| Manufacturer | Khandelwal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed and out of reach of children. Do not freeze. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two agents with complementary actions in the gastrointestinal tract. Dicyclomine is a synthetic antispasmodic that blocks muscarinic acetylcholine receptors on intestinal smooth muscle, reducing parasympathetic stimulation and thereby relaxing spasm. It also has a direct relaxant effect on smooth muscle, which helps relieve cramping pain. Dimethicone is a polydimethylsiloxane with low surface tension; it does not reduce the amount of gas produced, but it changes the surface properties of gas bubbles so that small bubbles coalesce into larger ones that can be expelled more easily. The result is reduced abdominal distension and pressure. Because dicyclomine has anticholinergic activity, it can cause dry mouth, constipation, and blurred vision, while dimethicone acts locally in the gut and is largely not absorbed.
Mechanism Steps
💡 How to Take spasmokay drop
Strength: Each dose of this drop formulation contains dicyclomine 10 mg and dimethicone 40 mg.
Dosage Information
| Adult Dosage | The adult dose of this medicine is not fixed and must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, and liver and kidney function. In general, this drop formulation is often used in children, but when prescribed for adults, the clinician will determine the exact dose and frequency. Do not self-medicate or adjust the dose without medical advice. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing of this medicine must be determined by a pediatrician based on the child's age, weight, and clinical condition. The drop formulation is commonly used in infants and children, but the exact dose and frequency vary. Do not use this medicine in infants under 6 months of age unless specifically prescribed by a pediatrician. Always use the dropper supplied with the pack for accurate measurement. |
| Elderly Dosage | Elderly patients are more sensitive to the anticholinergic effects of dicyclomine, such as confusion, constipation, dry mouth, and urinary retention. The dose should be individualized by a clinician, and the lowest effective dose should be used for the shortest duration necessary. Close monitoring is advised. |
| Renal Impairment | Dicyclomine and its metabolites are excreted by the kidneys. In patients with significant renal impairment, the dose may need to be reduced or the medicine used with caution, as determined by a qualified clinician. Specific dosing guidelines for this formulation are not established from the available information. |
| Hepatic Impairment | Dicyclomine is metabolized in the liver. In patients with hepatic impairment, the dose may need to be reduced or the medicine used with caution, as determined by a qualified clinician. Specific dosing guidelines for this formulation are not established from the available information. |
| Maximum Daily Dose | The maximum daily dose of this medicine must be determined by a qualified clinician based on the patient's age, weight, indication, and clinical response. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of spasmokay drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other anticholinergics | Major | |
| Amantadine | Major | |
| Potassium chloride tablets | Major | |
| Metoclopramide | Moderate | |
| Antacids | Moderate | |
| Levodopa | Moderate | |
| Activated charcoal | Minor | |
| Loperamide | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Other anticholinergic medicines such as antihistamines, tricyclic antidepressants, and antispasmodics
- Amantadine
- Potassium chloride tablets
⚡ Moderate Interactions
- Metoclopramide and other prokinetic agents
- Antacids containing aluminum or magnesium
- Levodopa
🍷 Alcohol Interaction
Alcohol may increase drowsiness, dizziness, and impaired coordination when taken with this medicine. It is advisable to avoid alcohol during treatment, especially if the patient needs to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to dicyclomine, dimethicone, or any component of the formulation","Glaucoma (narrow-angle)","Urinary retention or bladder neck obstruction","Myasthenia gravis","Severe ulcerative colitis or toxic megacolon","Obstructive gastrointestinal disease or paralytic ileus","Infants less than 6 months of age, unless specifically prescribed by a pediatrician"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients because they are more sensitive to anticholinergic effects such as confusion, constipation, and urinary retention.","Use with caution in patients with autonomic neuropathy, liver disease, kidney disease, or heart disease.","May cause drowsiness or blurred vision; avoid driving or operating machinery until you know how this medicine affects you.","Do not exceed the recommended dose, especially in infants and children.","Prolonged use may mask other serious gastrointestinal conditions; consult a doctor if symptoms persist.","Keep out of reach of children and use the supplied dropper for accurate measurement."]
🤱 Lactation Safety
It is not known whether dicyclomine passes into breast milk in amounts that could affect a nursing infant. Dimethicone is not absorbed and is unlikely to affect the infant. Breastfeeding mothers should consult a doctor before using this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe anticholinergic symptoms such as dry mouth, flushing, fast heartbeat, dilated pupils, blurred vision, confusion, agitation, hallucinations, urinary retention, and in severe cases, seizures or coma. If overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal if given early, intravenous fluids, and management of specific symptoms. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If a dose is missed, give or take it as soon as you remember, provided it is not almost time for the next dose. If it is nearly time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to make up for a missed one.
Additional Safety Advice
Use this medicine only as directed by a qualified clinician, and measure each dose with the dropper provided with the pack. Do not use it for longer than advised without medical review, because ongoing abdominal pain or gas can have other causes that need evaluation. Keep the bottle tightly closed and out of reach of children. Avoid giving this medicine to infants under the age recommended by your doctor, and never share the dropper with another person. If the patient has glaucoma, an enlarged prostate, urinary retention, or myasthenia gravis, this medicine is usually not suitable. Avoid driving or operating machinery if you feel drowsy or have blurred vision. Tell your doctor about all other medicines, especially antihistamines, antidepressants, and antispasmodics, because they can add to the side effects. Seek medical help if symptoms do not improve within the expected time or if new symptoms appear.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience anticholinergic side effects such as confusion, constipation, dry mouth, blurred vision, and urinary retention. Use the lowest effective dose for the shortest duration and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety of dicyclomine in pregnancy is not fully established, and it should be used only if clearly needed and advised by a clinician.
🏥 Post-Surgery Considerations
This medicine may be used after certain abdominal surgeries to relieve gas and cramping, but only if prescribed by the treating surgeon. Follow the surgeon's instructions regarding diet and activity.
🦷 Dental Procedures
There are no specific dental precautions, but inform your dentist about all medicines you are taking, including this one, before any procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while taking this medicine, but if you feel drowsy or dizzy, avoid activities that require alertness, including certain exercises that carry a risk of falls.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or blurred vision in some people. If you experience these effects, avoid driving, operating heavy machinery, or performing tasks that require full alertness. In children, it may cause sleepiness, so supervise activities accordingly.
🛑 When to Stop This Medicine
Stop this medicine and consult a doctor if symptoms do not improve within the expected time, if side effects become troublesome, or if new symptoms such as fever, vomiting, or blood in stool appear. Do not stop a prescribed course without consulting the doctor, especially in infants.
📅 Long-Term Use Effects
Long-term use of this medicine is not generally recommended without medical supervision. Prolonged use of dicyclomine may lead to persistent anticholinergic effects such as constipation, dry mouth, and urinary retention, and may mask underlying gastrointestinal conditions. Regular review by a clinician is advised if long-term use is considered.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Proper positioning during feeding and frequent burping can reduce gas and colic symptoms.
Evidence: Well-establishedSome probiotic strains may help reduce colic symptoms in infants, but evidence is mixed.
Evidence: LimitedEliminating certain allergens from the mother's diet may help in some cases of infant colic.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and routine vaccines. Continue with the recommended vaccination schedule as advised by the pediatrician.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep the bottle tightly closed
❌ DON'T
Do not leave the cap loose
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer to another unmarked container
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Keep a copy of the prescription with you, especially for international travel, as some countries may require documentation for medicines. Store the bottle in a cool, dry place and avoid leaving it in a hot car or in direct sunlight. If traveling across time zones, continue with the usual dosing schedule as advised by your doctor, and consult the doctor if you are unsure about timing. Always keep the medicine in your hand luggage rather than checked baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to relieve cramping and gas within 30 to 60 minutes after administration, but the exact time can vary from person to person.
A: This medicine is commonly used in infants for colic when prescribed by a pediatrician. It should not be given to infants under 6 months of age unless specifically advised by a doctor.
A: It can be given with or after feeds if the doctor advises, as this may reduce stomach upset. Always follow the doctor's instructions.
A: Common side effects include dry mouth, constipation, drowsiness, dizziness, and blurred vision. These are usually mild and temporary.
A: If you remember within a short time, give the missed dose. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for spasmokay drop
View AllAlternative brands with exact same active ingredient:
-
colinol 10 mg/40 mg injectionNoel Pharma India Pvt Ltd ₹8.65 13.5% CHEAPER
-
spasmover dropCachet Pharmaceuticals Pvt Ltd ₹9.50 5% CHEAPER
-
Topspas 10 mg/40 mg DropPsychotropics India Ltd ₹11.72 17.2% COSTLIER
-
Spasmigon 10 mg/40 mg DropPasteur Laboratories Pvt Ltd ₹11.95 19.5% COSTLIER
-
colica syrupParex Pharmaceuticals Pvt Ltd ₹13.13 31.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be given to any baby with crying or gas without a doctor's advice.
Fact: This medicine should only be given when prescribed by a qualified clinician, because not all crying or gas is due to colic, and some causes need different treatment. - Myth: More medicine will relieve gas faster.
Fact: Increasing the dose does not improve gas relief and increases the risk of side effects such as drowsiness, constipation, and dry mouth. - Myth: This medicine is a digestive enzyme supplement.
Fact: This medicine is not an enzyme supplement. It contains an antispasmodic and an antifoaming agent that work differently. - Myth: This medicine can be used for any stomach pain.
Fact: This medicine is for cramping and gas-related pain. Other causes of stomach pain, such as infection or obstruction, require different treatment.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine and dimethicone combination drops
- Dicyclomine oral drops
- Dimethicone oral drops
Brand Alternatives
- Colimex Drops
- Colicaid Drops
- Dentogel Drops
- Neopeptine Drops