colica syrup - Dicyclomine (10mg) + Dimethicone (40mg) medicine

colica syrup

4.6 (14 reviews)
๐Ÿญ Parex Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is colica syrup used for?

Alspas (Dicyclomine + Dimethicone) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (10mg) + Dimethicone (40mg), which Dicyclomine: Antimuscarinic, relaxes smooth muscle; Dimethicone: Defoaming agent. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Dicyclomine + Dimethicone
  • Manufacturer: Parex Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š colica syrup Uses & Benefits

Irritable bowel syndrome, abdominal cramps, flatulence, dyspepsia

Off-label uses: Infant colic (not recommended), functional dyspepsia

๐Ÿ“‹ Drug Information

Generic Name(s)Dicyclomine + Dimethicone
Brand NameAlspas
ManufacturerParex Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + Antiflatulent
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingDicyclomine: ~90%; Dimethicone: Not bound
MetabolismDicyclomine: Hepatic (CYP450); Dimethicone: Not metabolized
Half-LifeDicyclomine: 1.8-2.5 hours; Dimethicone: Excreted unchanged
ExcretionDicyclomine: Renal (79.5%) and fecal (8.4%); Dimethicone: Feces
BioavailabilityDicyclomine: ~67%
Onset of ActionDicyclomine: 1-2 hours; Dimethicone: Rapid
Peak Plasma TimeDicyclomine: 1-1.5 hours
Duration of ActionDicyclomine: 4-6 hours; Dimethicone: Variable

How It Works

Dicyclomine: Antimuscarinic, relaxes smooth muscle; Dimethicone: Defoaming agent, reduces gas surface tension

Mechanism Steps

1Dicyclomine blocks muscarinic receptors in GI smooth muscle
2Reduces acetylcholine-mediated contractions
3Relieves spasms and pain

๐Ÿ’ก How to Take colica syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of colica syrup

โœ… Common Side Effects

  • Dry mouth
  • Dizziness
  • Blurred vision
  • Constipation
  • Nausea
  • Drowsiness

๐Ÿšจ Serious Side Effects

  • Paralytic ileus
  • Urinary retention
  • Tachycardia
  • Hallucinations
  • Heat stroke

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Agranulocytosis
  • Hepatitis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Anticholinergics Major Additive anticholinergic effects
Amantadine Major Increased anticholinergic side effects
Haloperidol Major Decreased antipsychotic efficacy
Phenothiazines Major Increased anticholinergic effects
Tricyclic antidepressants Major Additive anticholinergic effects
Antacids Moderate Reduced absorption of dicyclomine
Antidiarrheals Moderate Increased anticholinergic effects
Ketoconazole Moderate Increased dicyclomine levels
Metoclopramide Moderate Antagonism of GI effects
Cimetidine Minor Possible increased dicyclomine levels
Ranitidine Minor Possible increased dicyclomine levels

๐Ÿšจ Major Interactions

  • Anticholinergics
  • Amantadine
  • Haloperidol
  • Phenothiazines
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Antacids
  • Antidiarrheals
  • Ketoconazole
  • Metoclopramide

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ranitidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, glaucoma, obstructive uropathy, myasthenia gravis, gastrointestinal obstruction, severe ulcerative colitis, reflux esophagitis

๐Ÿ“Š Monitoring Parameters

Monitor for anticholinergic side effects, bowel sounds, abdominal distension

๐Ÿคฑ Lactation Safety

Caution; dicyclomine may suppress lactation

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive measures; physostigmine for severe anticholinergic symptoms

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

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