Innoplat 50mg Injection (cisplatin): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Decreased urine output or swelling in legs
- Hearing loss or ringing in the ears
- Numbness or tingling in hands or feet
- Fever, chills, or signs of infection
- Unusual bleeding or bruising
- Severe nausea or vomiting that prevents fluid intake
- Shortness of breath or chest pain
If experiencing severe symptoms, call emergency services immediately.
What is slatin 50mg infusion used for?
This medicine is a platinum-based chemotherapy drug given intravenously to treat several types of cancer, including testicular, ovarian, bladder, and lung cancers. It works by damaging cancer cell DNA to stop their growth.
- Generic Name: Cisplatin (50mg)
- Manufacturer: Venus Remedies Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 slatin 50mg infusion के बारे में (Hindi Summary)
उपयोग: यह दवा सिस्प्लाटिन 50 मिलीग्राम इंजेक्शन के रूप में एक कीमोथेरेपी दवा है, जिसका उपयोग विभिन्न प्रकार के कैंसर जैसे अंडकोष, अंडाशय, मूत्राशय, सिर और गर्दन तथा फेफड़ों के कैंसर के इलाज में किया जाता है। यह कैंसर कोशिकाओं के डीएनए को नुकसान पहुंचाकर उनकी वृद्धि को रोकती है। यह दवा केवल अस्पताल में योग्य चिकित्सक की देखरेख में ही दी जाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में गंभीर मतली और उल्टी, गुर्दे की समस्या, सुनने में कमी, हाथ-पैरों में झुनझुनी, थकान और रक्त कोशिकाओं की कमी शामिल हैं। गंभीर दुष्प्रभावों में गुर्दे की विफलता, बहरापन, तंत्रिका क्षति और गंभीर संक्रमण हो सकते हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा नियंत्रित वातावरण में ही दी जानी चाहिए। गुर्दे की सुरक्षा के लिए पर्याप्त तरल पदार्थ दिया जाता है। नियमित रूप से गुर्दे की कार्यप्रणाली, रक्त गणना और इलेक्ट्रोलाइट स्तर की जांच करवाएं। सुनने में बदलाव, सुन्नपन या झुनझुनी होने पर तुरंत बताएं। उपचार के दौरान और बाद में गर्भनिरोधक उपाय अपनाएं। स्तनपान न कराएं।
💊 slatin 50mg infusion Uses & Benefits
[{"condition":"Testicular cancer","description":"This medicine is a cornerstone of curative combination chemotherapy regimens for testicular germ cell tumors.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used as first-line therapy in combination with other agents for advanced ovarian cancer.","evidence":"Well-established"},{"condition":"Bladder cancer","description":"Part of neoadjuvant and adjuvant combination regimens for muscle-invasive bladder cancer.","evidence":"Well-established"},{"condition":"Head and neck cancers","description":"Used concurrently with radiation therapy or as part of combination chemotherapy for locally advanced disease.","evidence":"Well-established"},{"condition":"Non-small cell lung cancer","description":"Combined with other chemotherapy drugs for advanced or metastatic disease.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cervical cancer","description":"Sometimes used in combination regimens for advanced cervical cancer, though evidence is more limited compared to standard uses.","evidence":"Limited"},{"condition":"Small cell lung cancer","description":"Occasionally used in combination therapy, but other platinum agents may be preferred.","evidence":"Limited"}]
Primary treatment for: Testicular cancer, ovarian cancer, bladder cancer, head and neck cancer, non-small cell lung cancer
Also treats: Cervical cancer, Small cell lung cancer
📋 Drug Information
| Generic Name(s) | Cisplatin (50mg) |
| Brand Name | slatin 50mg infusion |
| Manufacturer | Venus Remedies Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Platinum compounds-Anticancer |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store unopened vials at 20-25°C (68-77°F). Protect from light. Reconstituted solution should be used immediately or stored as per institutional guidelines. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Cisplatin is included in the WHO Model List of Essential Medicines for the treatment of various cancers. |
| ICMR Guideline | ICMR guidelines recommend cisplatin-based chemotherapy for testicular, ovarian, and head and neck cancers as per standard protocols. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cisplatin exerts its anticancer effects by forming covalent adducts with DNA, primarily intrastrand cross-links between adjacent guanine bases. These cross-links distort the DNA double helix, preventing transcription and replication, which ultimately triggers apoptosis in rapidly dividing cancer cells. The drug also induces oxidative stress and mitochondrial damage, contributing to its cytotoxic effects.
Mechanism Steps
💡 How to Take slatin 50mg infusion
Strength: 50 mg lyophilized powder for injection
Dosage Information
| Adult Dosage | The dose of this medicine is highly individualized and depends on the specific cancer type, stage, combination regimen, and patient factors such as renal function and performance status. Common regimens may use 50-100 mg/m² intravenously every 3-4 weeks. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more susceptible to nephrotoxicity, ototoxicity, and neurotoxicity. Dose reduction and close monitoring are advised. |
| Renal Impairment | Dose reduction is required in patients with renal impairment. Cisplatin is contraindicated in severe renal impairment. Monitor creatinine clearance and adjust dose accordingly. |
| Hepatic Impairment | No specific dose adjustment guidelines for hepatic impairment; use with caution and monitor liver function. |
| Maximum Daily Dose | Not applicable; dosing is per cycle, not daily. Maximum cumulative dose is limited by toxicity. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of slatin 50mg infusion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Amphotericin B | Major | |
| Loop diuretics | Major | |
| Live vaccines | Major | |
| Phenytoin | Moderate | |
| Warfarin | Moderate | |
| Paclitaxel | Moderate | |
| Docetaxel | Moderate | |
| Bleomycin | Moderate | |
| Radiation therapy | Major |
🚨 Major Interactions
- Nephrotoxic drugs (e.g., aminoglycosides, amphotericin B)
- Ototoxic drugs (e.g., aminoglycosides, loop diuretics)
- Live vaccines
⚡ Moderate Interactions
- Phenytoin
- Warfarin
🍷 Alcohol Interaction
Avoid alcohol consumption during treatment as it may worsen nausea, dehydration, and liver stress.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cisplatin or other platinum compounds","Severe renal impairment","Severe bone marrow suppression","Pre-existing hearing impairment","Pregnancy and lactation"]
⚠️ Warnings & Precautions
["Administer only under supervision of an experienced oncologist.","Ensure adequate hydration before and after infusion.","Use antiemetics to prevent severe nausea and vomiting.","Monitor renal function closely; dose adjust in renal impairment.","Avoid concurrent nephrotoxic or ototoxic drugs.","Advise patients on contraception during and after treatment.","Handle cytotoxic drug with appropriate precautions."]
🤱 Lactation Safety
Contraindicated; do not breastfeed during treatment and for at least 2 weeks after the last dose.
💊 Overdose Management
There is no specific antidote for cisplatin overdose. Management is supportive and symptomatic, focusing on hydration, electrolyte replacement, and monitoring for toxicity. Immediate medical attention is required.
⏰ Missed Dose
This medicine is administered by a healthcare professional. If a scheduled dose is missed, contact your oncology team immediately to reschedule. Do not attempt to self-administer.
Additional Safety Advice
This medicine must only be administered by a qualified healthcare professional in a controlled clinical setting. Patients should receive adequate intravenous hydration before and after infusion to protect the kidneys. Regular blood tests to monitor kidney function, blood counts, and electrolyte levels are essential. Report any hearing changes, numbness, or tingling immediately. Avoid contact with people who have active infections. Use effective contraception during treatment and for several months afterward. Do not breastfeed while receiving this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of nephrotoxicity, ototoxicity, and neurotoxicity. Dose reduction and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
Cisplatin is contraindicated in pregnancy. Women of childbearing potential should use effective contraception during treatment and for at least 6 months after. Men should use contraception for at least 3 months after treatment.
🏥 Post-Surgery Considerations
Cisplatin may be used as adjuvant or neoadjuvant therapy after surgery. Ensure adequate wound healing and discuss timing with your oncologist.
🦷 Dental Procedures
Inform your dentist about cisplatin treatment. Dental procedures may need to be postponed due to increased risk of bleeding and infection. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during treatment. Light activities like walking may be beneficial, but consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Cisplatin treatment can cause fatigue, nausea, and neuropathy, which may affect your ability to work or drive. Avoid driving if you feel dizzy or fatigued. Discuss work accommodations with your employer.
🛑 When to Stop This Medicine
Do not stop treatment without consulting your oncologist. Treatment may be stopped or modified if severe toxicity occurs, such as kidney failure, hearing loss, or severe neuropathy.
📅 Long-Term Use Effects
Long-term effects of cisplatin may include persistent peripheral neuropathy, hearing loss, and kidney impairment. Regular monitoring of renal function, hearing, and neurological status is recommended for survivors. Secondary malignancies are a rare long-term risk.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A less nephrotoxic platinum analogue, but with different efficacy and side effect profile.
Evidence: Well-establishedFor certain cancers, targeted therapies may be used instead of or in addition to chemotherapy.
Evidence: Well-established for specific indications💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during and shortly after cisplatin treatment due to immunosuppression. Inactivated vaccines may be given, but response may be reduced.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting and is not for self-administration. If you are traveling for treatment, carry a copy of your prescription and medical records. Store vials as directed and avoid extreme temperatures. Inform security about any medical devices or medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Cisplatin's antitumor effects are not immediate; response typically requires weeks of treatment and is assessed through imaging and tumor markers.
A: No, cisplatin must be administered by a healthcare professional in a clinical setting.
A: Avoid alcohol, live vaccines, and nephrotoxic or ototoxic drugs. Stay well hydrated.
🤔 Common Patient Concerns
🔄 Substitutes for slatin 50mg infusion
View AllAlternative brands with exact same active ingredient:
-
cizcan 50mg injectionNeon Laboratories Ltd ₹261.16 17.1% CHEAPER
-
Stritin 50mg InjectionMylan Pharmaceuticals Pvt Ltd ₹284.82 9.6% CHEAPER
-
oncoplatin aq 50mg infusionSun Pharmaceutical Industries Ltd ₹300.00 4.8% CHEAPER
-
cisteen 50mg infusionVhb Life Sciences Inc ₹309.52 1.7% CHEAPER
-
cytoplatin 50mg infusionCipla Ltd ₹314.53 0.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Cisplatin can be taken at home.
Fact: Cisplatin must be administered by a healthcare professional in a clinical setting. - Myth: Cisplatin has no serious side effects.
Fact: Cisplatin can cause severe kidney damage, hearing loss, and bone marrow suppression.
🔄 Alternative Options
Generic Alternatives
- Cisplatin
Brand Alternatives
- Innoplat 50mg injection