cytoplatin 50mg infusion - Cisplatin (50mg) medicine

cytoplatin 50mg infusion

4.6 (8 reviews)
๐Ÿญ Cipla Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
โš ๏ธ Nephrotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cytoplatin 50mg infusion used for?

Blastolem 50mg Injection (Cisplatin) is used to treat ANTI NEOPLASTICS. It contains Cisplatin (50mg), which Cisplatin forms intrastrand and interstrand DNA crosslinks, inhibiting DNA repli. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cisplatin
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š cytoplatin 50mg infusion Uses & Benefits

Testicular cancer, ovarian cancer, bladder cancer, head and neck cancer, lung cancer, cervical cancer, melanoma, lymphoma

Off-label uses: Esophageal cancer, gastric cancer, hepatocellular carcinoma, osteosarcoma

๐Ÿ“‹ Drug Information

Generic Name(s)Cisplatin
Brand NameBlastolem 50mg Injection
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassPlatinum compounds-Anticancer
Route of AdministrationIntravenous infusion
StorageStore at 20-25ยฐC; protect from light; do not refrigerate
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionNot applicable (intravenous administration)
DistributionWidely distributed in tissues; highest concentrations in liver, kidneys, and skin
Protein Binding>90%
MetabolismUndergoes nonenzymatic conversion to inactive metabolites; minor hepatic metabolism
Half-Life30-100 hours (biphasic: initial 20-30 min, terminal 24-48 hours)
ExcretionRenal (70-90% within 24 hours); primarily as unchanged drug
Bioavailability100% (intravenous)
Onset of ActionRapid (minutes to hours)
Peak Plasma TimeImmediately after infusion
Duration of ActionVariable; depends on cell cycle and tumor type

How It Works

Cisplatin forms intrastrand and interstrand DNA crosslinks, inhibiting DNA replication and transcription, leading to apoptosis

Mechanism Steps

1Cisplatin enters cells via passive diffusion or copper transporter CTR1
2Intracellularly, chloride ligands are replaced by water molecules, forming active aquated species
3Aquated cisplatin reacts with DNA, preferentially binding to N7 position of guanine

๐Ÿ’ก How to Take cytoplatin 50mg infusion

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cytoplatin 50mg infusion

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Nephrotoxicity
  • Myelosuppression
  • Ototoxicity
  • Electrolyte disturbances

๐Ÿšจ Serious Side Effects

  • Acute renal failure
  • Severe myelosuppression
  • Anaphylaxis
  • Neurotoxicity
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Hemolytic uremic syndrome
  • Pancreatitis
  • SIADH
  • Cardiotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aminoglycosides Major Increased nephrotoxicity and ototoxicity
Loop diuretics Major Increased nephrotoxicity
Warfarin Moderate Increased anticoagulant effect
Phenytoin Moderate Decreased phenytoin levels

๐Ÿšจ Major Interactions

  • Aminoglycosides
  • Loop diuretics
  • Nephrotoxic drugs
  • Ototoxic drugs
  • Myelosuppressive agents

โšก Moderate Interactions

  • Anticoagulants
  • Phenytoin
  • Methotrexate
  • Bleomycin

โ„น๏ธ Minor Interactions

  • Antihistamines
  • Antiemetics

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity and dehydration risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cisplatin or platinum compounds, severe renal impairment, myelosuppression, pregnancy, lactation

๐Ÿ“Š Monitoring Parameters

Renal function (BUN, creatinine), electrolytes (Mg, K, Ca), complete blood count, audiometry, liver function tests

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be considered; monitor renal function, electrolytes, and hearing

โฐ Missed Dose

Do not double dose; contact physician immediately

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cytoplatin 50mg infusion

View All

Alternative brands with exact same active ingredient (Cisplatin (50mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

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