Bactofix 400mg Tablet DT: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing.
- Severe diarrhea: watery or bloody stools, abdominal cramps, fever.
- Signs of kidney problems: decreased urine output, swelling in legs, fatigue.
- Seizures or confusion.
- Unusual bleeding or bruising.
- Yellowing of skin or eyes (jaundice).
If experiencing severe symptoms, call emergency services immediately.
What is secef 400mg tablet used for?
This medicine is a cephalosporin antibiotic used to treat bacterial infections such as urinary tract infections, respiratory infections, and gonorrhea. It works by killing bacteria.
- Generic Name: Cefixime (400mg)
- Manufacturer: Novartis India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 secef 400mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे कि मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, कान, नाक और गले के संक्रमण, और गोनोरिया। यह बैक्टीरिया को मारकर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी प्रतिक्रिया, गंभीर दस्त, और गुर्दे की समस्याएं हो सकती हैं। किसी भी गंभीर दुष्प्रभाव के लिए तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी दवाओं और एलर्जी के बारे में बताएं। शराब से बचें। गुर्दे की समस्या हो तो डॉक्टर से सलाह लें। पूरा कोर्स पूरा करें।
💊 secef 400mg tablet Uses & Benefits
[{"condition":"Urinary tract infections","description":"This medicine is effective against common bacteria that cause urinary tract infections, such as Escherichia coli and Klebsiella pneumoniae.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"It is used to treat infections like acute bronchitis and exacerbations of chronic bronchitis.","evidence":"Well-established"},{"condition":"Ear, nose, and throat infections","description":"This medicine is prescribed for conditions such as otitis media, sinusitis, and pharyngitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"It is used as a single-dose treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for early Lyme disease, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Ear, nose, and throat infections, Gonorrhea
📋 Drug Information
| Generic Name(s) | Cefixime (400mg) |
| Brand Name | secef 400mg tablet |
| Manufacturer | Novartis India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific penicillin-binding proteins inside the bacterial cell wall. This binding inhibits the final step of cell wall synthesis, leading to a weakened cell wall and ultimately causing the bacteria to die. It is bactericidal, meaning it kills the bacteria directly.
Mechanism Steps
💡 How to Take secef 400mg tablet
Strength: This medicine is available as a 400 mg tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 400 mg once daily or 200 mg twice daily, depending on the type and severity of the infection. For uncomplicated gonorrhea, a single 400 mg dose is recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require dose adjustment. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with renal impairment (creatinine clearance < 60 mL/min), the dose may need to be reduced. Consult a doctor for specific dosing recommendations. |
| Hepatic Impairment | No specific dose adjustment is recommended for patients with hepatic impairment, but caution is advised. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of secef 400mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime or other cephalosporins","History of severe allergic reaction to penicillins"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney impairment; dose adjustment may be needed.","May cause Clostridium difficile-associated diarrhea; if severe diarrhea occurs, stop the medicine and consult a doctor.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for viral infections; it is ineffective against viruses.","Complete the full course as prescribed to prevent resistance."]
🤱 Lactation Safety
This medicine is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose symptoms may include nausea, vomiting, and diarrhea. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. This medicine is not significantly removed by hemodialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to penicillin or other antibiotics. Tell your doctor about all medications you are taking, especially blood thinners like warfarin, as this medicine may increase the risk of bleeding. Avoid alcohol while taking this medicine to reduce the risk of stomach upset. If you have kidney problems, your doctor may need to adjust your dose. Do not share this medicine with others, even if they have similar symptoms. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for signs of superinfection and renal impairment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe but should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with other medications or affect healing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue, avoid strenuous exercise until you feel better. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance and superinfections. It is generally prescribed for short courses. Prolonged use should be monitored by a doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture. If crossing time zones, adjust your dosing schedule gradually. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for secef 400mg tablet
View AllAlternative brands with exact same active ingredient:
-
zifi 400mg tabletFDC Ltd ₹97.50 50.3% CHEAPER
-
topcef 400mg tabletTorrent Pharmaceuticals Ltd ₹108.17 44.9% CHEAPER
-
cefix 400mg tabletCipla Ltd ₹115.57 41.1% CHEAPER
-
cefcea 400mg tablet dtAlcea Biotech Pvt Ltd ₹120.00 38.9% CHEAPER
-
cefolac 400mg tabletMacleods Pharmaceuticals Pvt Ltd ₹125.00 36.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections, not viruses. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
🔄 Alternative Options
Generic Alternatives
- Cefixime 400 mg tablet
Brand Alternatives
- Bactofix 400mg tablet DT