cefix 400mg tablet - Uses, Price, Side Effects & Substitutes
What is cefix 400mg tablet used for?
Abixim (Cefixime) is used to treat ANTI INFECTIVES. It contains Cefixime (400mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefixime
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cefix 400mg tablet Uses & Benefits
Treatment of respiratory tract infections, urinary tract infections, otitis media, pharyngitis, tonsillitis, gonorrhea.
Off-label uses: Lyme disease, typhoid fever, prophylaxis of bacterial endocarditis.
๐ Drug Information
| Generic Name(s) | Cefixime |
| Brand Name | Abixim |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidation and disrupting cell wall integrity.
Mechanism Steps
๐ก How to Take cefix 400mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cefix 400mg tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe hypersensitivity reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Seizures
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Thrombocytopenia
- Interstitial nephritis
- Hepatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Probenecid | Major | Decreased renal excretion of cefixime, increased plasma levels |
| Live typhoid vaccine | Major | Reduced vaccine efficacy |
| BCG vaccine | Moderate | Reduced vaccine efficacy |
| Cholera vaccine | Moderate | Reduced vaccine efficacy |
| Antacids | Minor | Possible decreased absorption of cefixime |
| Iron supplements | Minor | Possible decreased absorption of cefixime |
๐จ Major Interactions
- Warfarin
- Probenecid
- Live typhoid vaccine
โก Moderate Interactions
- BCG vaccine
- Cholera vaccine
โน๏ธ Minor Interactions
- Antacids
- Iron supplements
๐ฝ๏ธ Food Interactions
Food delays absorption but does not significantly reduce extent; may be taken with or without food.
๐ท Alcohol Interaction
No known interaction; however, alcohol may increase risk of gastrointestinal side effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefixime or other cephalosporins; severe renal impairment (CrCl < 60 mL/min) without dose adjustment.
๐ Monitoring Parameters
Renal function, signs of hypersensitivity, prothrombin time if on warfarin.
๐คฑ Lactation Safety
Excreted in small amounts; considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cefix 400mg tablet
View AllAlternative brands with exact same active ingredient (Cefixime (400mg)):
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zifi 400mg tabletFDC Ltd โน97.50 15.6% CHEAPER
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topcef 400mg tabletTorrent Pharmaceuticals Ltd โน108.17 6.4% CHEAPER
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cefcea 400mg tablet dtAlcea Biotech Pvt Ltd โน120.00 3.8% COSTLIER
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cefolac 400mg tabletMacleods Pharmaceuticals Pvt Ltd โน125.00 8.2% COSTLIER
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hifen 400 tabletHetero Drugs Ltd โน164.91 42.7% COSTLIER
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mucifi 400mg tabletCyper Drugs & Pharmaceuticals Pvt Ltd โน170.00 47.1% COSTLIER
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c tax-o 400mg tabletZuventus Healthcare Ltd โน178.13 54.1% COSTLIER
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secef 400mg tabletNovartis India Ltd โน196.25 69.8% COSTLIER
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Torifix 400mg TabletNexkem Pharmaceuticals Pvt Ltd โน206.25 78.5% COSTLIER
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si fixim 400mg tablet dtManeesh Pharmaceuticals Ltd โน207.78 79.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.