Scodox-AZ 200mg/250mg Tablet - Cefpodoxime Proxetil (200mg) + Azithromycin (250mg) medicine

Azibact CF 200 mg/250 mg Tablet: Complete Information

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🏭 Pharma Drugs & Chemicals 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or bloody diarrhea
  • Yellowing of skin or eyes
  • Irregular heartbeat or fainting
  • Severe skin rash with blistering or peeling
  • Persistent high fever despite treatment

If experiencing severe symptoms, call emergency services immediately.

What is Scodox-AZ 200mg/250mg Tablet used for?

This medicine is a combination antibiotic containing Cefpodoxime Proxetil 200 mg and Azithromycin 250 mg. It is used to treat various bacterial infections, including respiratory, skin, and sexually transmitted infections. It works by killing or stopping the growth of bacteria. Take it exactly as prescribed, with food, and complete the full course.

  • Generic Name: Cefpodoxime Proxetil (200mg) + Azithromycin (250mg)
  • Manufacturer: Pharma Drugs & Chemicals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Scodox-AZ 200mg/250mg Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफपोडॉक्सिम प्रोक्सेटिल 200 मिलीग्राम और एज़िथ्रोमाइसिन 250 मिलीग्राम का संयोजन है। यह बैक्टीरियल संक्रमणों जैसे श्वसन तंत्र, त्वचा, और यौन संचारित संक्रमणों के इलाज के लिए उपयोग की जाती है। यह बैक्टीरिया को मारती है या उनकी वृद्धि रोकती है। इसे डॉक्टर के निर्देशानुसार भोजन के साथ लें और पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द, और दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लीवर की समस्या, और दिल की धड़कन में गड़बड़ी हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। भोजन के साथ लें। शराब से बचें। अन्य दवाओं के बारे में डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Scodox-AZ 200mg/250mg Tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat bacterial pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Helps manage flare-ups of chronic bronchitis due to bacterial infection.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Effective against sinus infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for uncomplicated skin infections like cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Urethritis and cervicitis","description":"May be used for sexually transmitted infections like chlamydia and gonorrhea.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Typhoid fever","description":"Sometimes used off-label for enteric fever, but resistance is common.","evidence":"Limited"},{"condition":"Dental infections","description":"May be used as an adjunct for dental abscesses, but not first-line.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Sexually transmitted infections

📋 Drug Information

Generic Name(s)Cefpodoxime Proxetil (200mg) + Azithromycin (250mg)
Brand NameScodox-AZ 200mg/250mg Tablet
ManufacturerPharma Drugs & Chemicals
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in original packaging.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this combination only when a broad-spectrum antibiotic is justified; avoid unnecessary use to prevent resistance.
2
Advise patients to take the tablet with food to improve absorption and reduce GI upset.
3
Warn patients about the potential for QT prolongation, especially if they have cardiac risk factors or are on other QT-prolonging drugs.
4
Instruct patients to complete the full course even if symptoms improve.
5
Monitor renal and hepatic function in patients with pre-existing impairment.
6
Educate patients about the signs of allergic reactions and when to seek emergency care.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine is commonly prescribed for respiratory infections.
Likely Use
✅
Skin redness and swelling
Used for skin and soft tissue infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefpodoxime proxetil is absorbed from the gastrointestinal tract after oral administration and is rapidly hydrolyzed to cefpodoxime. Azithromycin is also absorbed orally, with bioavailability approximately 37%. Food may affect absorption of cefpodoxime; taking with food can enhance absorption.
DistributionCefpodoxime distributes widely into tissues and body fluids, including lung, tonsil, and prostate. Azithromycin distributes extensively into tissues, with high concentrations in phagocytes and fibroblasts, and is transported to infection sites.
Protein BindingCefpodoxime: approximately 20-30% bound to plasma proteins. Azithromycin: approximately 7-50% bound, concentration-dependent.
MetabolismCefpodoxime is minimally metabolized. Azithromycin is partially metabolized in the liver, primarily by CYP3A4, but mainly eliminated unchanged.
Half-LifeCefpodoxime: approximately 2-3 hours. Azithromycin: approximately 68 hours (due to extensive tissue distribution).
ExcretionCefpodoxime is primarily excreted unchanged in urine (80%). Azithromycin is excreted mainly in bile as unchanged drug, with some renal excretion.
BioavailabilityCefpodoxime: approximately 50% when taken with food. Azithromycin: approximately 37%.
Onset of ActionAntibacterial effects begin within hours, but clinical improvement may take 1-3 days.
Peak Plasma TimeCefpodoxime: 2-3 hours. Azithromycin: 2-3 hours.
Duration of ActionCefpodoxime: 8-12 hours. Azithromycin: prolonged tissue levels allow once-daily dosing for 3-5 days.

How It Works

This medicine combines two antibiotics with different mechanisms. Cefpodoxime proxetil is a prodrug that is hydrolyzed to cefpodoxime, which inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis. Azithromycin binds to the 50S ribosomal subunit of the bacterial ribosome, inhibiting protein synthesis and thereby stopping bacterial growth. The combination provides broad-spectrum coverage against many Gram-positive and Gram-negative bacteria, as well as atypical pathogens.

Mechanism Steps

1
Cefpodoxime inhibits cell wall synthesis: Cefpodoxime binds to penicillin-binding proteins, blocking the cross-linking of peptidoglycan in the bacterial cell wall, causing cell lysis and death.
2
Azithromycin inhibits protein synthesis: Azithromycin binds to the 50S ribosomal subunit, preventing the translocation step of protein synthesis, thereby inhibiting bacterial growth.
3
Combined antibacterial effect: The two mechanisms work together to kill or inhibit a broad range of bacteria, including those that may be resistant to one of the components.

💡 How to Take Scodox-AZ 200mg/250mg Tablet

Strength: Tablet containing Cefpodoxime Proxetil 200 mg and Azithromycin 250 mg.

1Take the tablet with a full glass of water.
2Take with food to enhance absorption and reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Do not take with antacids; separate by at least 2 hours.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally twice daily, or as prescribed by your doctor. The dose and duration depend on the type and severity of infection, renal function, and other factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution and monitor for side effects.
Renal ImpairmentDose adjustment is recommended in patients with creatinine clearance less than 30 mL/min. Consult your doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Monitor liver function. Dose adjustment may be needed.
Maximum Daily DoseThe maximum recommended dose is one tablet twice daily, but this may vary based on indication and clinical judgment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Enhances absorption and reduces stomach upset.
Antacids
Avoid taking together
Reduces absorption of cefpodoxime.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Scodox-AZ 200mg/250mg Tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If severe or bloody, seek medical attention.
Abdominal pain (Common (3-5%))
Usually temporary. If severe, contact your doctor.
Headache (Common (3-5%))
Rest and hydrate. If persistent, consult your doctor.
Rash (Uncommon (1-3%))
Stop the medicine and consult your doctor if rash develops.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe, persistent diarrhea, abdominal cramps, or blood in stool.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
QT prolongation and arrhythmias (Rare (<0.1%))
Seek medical attention if you experience palpitations, dizziness, or fainting.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention if you develop severe blistering rash, peeling skin, or sores in mouth.
Torsades de pointes
Call emergency services if you experience irregular heartbeat, fainting, or seizures.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Antacids Major
Ergotamine Major
Digoxin Moderate
Cyclosporine Moderate
H2 blockers Moderate
Oral contraceptives Minor
Theophylline Minor

🚨 Major Interactions

  • Warfarin
  • Antacids containing aluminum or magnesium
  • Ergotamine

⚡ Moderate Interactions

  • Digoxin
  • Cyclosporine
  • H2 blockers (e.g., ranitidine)

🍷 Alcohol Interaction

Alcohol may increase the risk of liver toxicity and stomach upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins, penicillins, or macrolides","History of cholestatic jaundice with prior azithromycin use","Severe hepatic impairment","Concurrent use with ergotamine"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be required.","May cause Clostridioides difficile-associated diarrhea; if severe diarrhea occurs, stop and consult doctor.","Avoid in patients with known QT prolongation or taking QT-prolonging drugs.","May reduce efficacy of oral contraceptives; use backup method.","Not recommended for viral infections.","Complete the full course to prevent resistance."]

🤱 Lactation Safety

Both cefpodoxime and azithromycin are excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and hearing loss. Seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered for cefpodoxime but not for azithromycin.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take with food to reduce stomach upset. Avoid alcohol while taking this medicine. Inform your doctor about all other medicines you are taking, especially blood thinners, antacids, and heart medications. Do not share this medicine with others. Keep out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects, especially kidney and heart rhythm issues. Dose adjustment may be needed based on renal function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Both components are pregnancy category B, but use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated.
🥗
Get plenty of rest to help your body fight infection.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hand hygiene to prevent spread of infection.
🧘
Avoid close contact with others while infectious.

🏋️ Exercise Considerations

Rest is recommended during acute infection. Gradually resume exercise as you feel better. Avoid strenuous activity if you have fever or fatigue.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Avoid alcohol.
Stay hydrated with water and clear fluids.
Eat light, easily digestible meals if you have nausea.

💼 Impact on Daily Work & Life

You may feel tired or have mild stomach upset, but most people can continue daily activities. Avoid driving if you feel dizzy or unwell.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early can lead to relapse and resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to bacterial resistance, superinfections, and rarely liver or kidney toxicity. It should only be used for the prescribed duration. Regular monitoring of liver and kidney function may be needed if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Symptomatic treatment

For viral infections, rest, fluids, and over-the-counter remedies may be sufficient.

Evidence: Well-established
Narrow-spectrum antibiotics

If culture results identify a specific bacterium, a targeted antibiotic may be preferred.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor about timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with community-acquired pneumonia
He was prescribed this medicine for 7 days. He took it with food as directed and completed the course. His fever subsided in 3 days, and cough improved by day 5. He experienced mild nausea initially, which resolved after taking it with meals.
💡 Lesson: Taking the medicine with food reduces side effects and completing the course ensures full recovery.
👤 A 28-year-old woman with skin infection
She was given this medicine for cellulitis. She noticed improvement in redness and pain within 2 days. She was advised to avoid alcohol and use backup contraception. She completed the 5-day course without any serious side effects.
💡 Lesson: Adhering to the prescribed duration and following safety advice leads to successful treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-3 days, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, take it with food to enhance absorption and reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Scodox-AZ 200mg/250mg Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course to prevent bacterial resistance and relapse.
  • Myth: Antibiotics can be shared with others.
    Fact: Never share antibiotics; they are prescribed for a specific individual and condition.

🔄 Alternative Options

Generic Alternatives

  • Cefpodoxime Proxetil 200 mg + Azithromycin 250 mg tablet (various manufacturers)

Brand Alternatives

  • Azibact CF 200 mg/250 mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefpodoxime + Azithromycin","composition":"Cefpodoxime Proxetil 200 mg + Azithromycin 250 mg","uses":"Broad-spectrum bacterial infections","notes":"Combination of cephalosporin and macrolide."},{"medicine":"Cefixime + Azithromycin","composition":"Cefixime 200 mg + Azithromycin 250 mg","uses":"Similar indications","notes":"Cefixime is a third-generation cephalosporin."}]

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