Satrogyl-O Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is satromax o 300 mg/200 mg tablet used for?
This medicine is a combination of Satranidazole and Ofloxacin used to treat mixed infections caused by anaerobic bacteria and protozoa. It works by damaging microbial DNA and inhibiting bacterial replication. It is available as an immediate-release tablet for oral use.
- Generic Name: Satranidazole (300mg) + Ofloxacin (200mg)
- Manufacturer: Indchemie Health Specialities Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 satromax o 300 mg/200 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सैट्रानिडाजोल और ऑफ्लोक्सासिन का संयोजन है, जिसका उपयोग एनारोबिक बैक्टीरिया और प्रोटोजोआ के कारण होने वाले मिश्रित संक्रमणों के इलाज के लिए किया जाता है। यह अमीबियासिस, जियार्डियासिस, ट्राइकोमोनिएसिस और बैक्टीरियल वेजिनोसिस जैसी स्थितियों में प्रभावी है। यह दवा सूक्ष्मजीवों के डीएनए को नष्ट करके और बैक्टीरिया के प्रजनन को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। उपचार के दौरान और अंतिम खुराक के 48 घंटे बाद तक शराब न लें। पर्याप्त पानी पिएं। धूप में जाने से बचें और सनस्क्रीन का उपयोग करें। चक्कर आने पर वाहन न चलाएं। गुर्दे या यकृत की समस्या, मिर्गी या टेंडन विकार हो तो डॉक्टर को बताएं।
💊 satromax o 300 mg/200 mg tablet Uses & Benefits
[{"condition":"Amoebiasis (intestinal and hepatic)","description":"Used to treat infections caused by Entamoeba histolytica, including dysentery and liver abscess.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Effective against Giardia lamblia, a common cause of diarrheal illness.","evidence":"Well-established"},{"condition":"Trichomoniasis","description":"Used in combination for treating Trichomonas vaginalis infections.","evidence":"Moderate"},{"condition":"Bacterial vaginosis","description":"Covers anaerobic bacteria associated with bacterial vaginosis.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"Used in combination regimens for mixed aerobic and anaerobic infections.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Pelvic inflammatory disease","description":"Sometimes used as part of a combination regimen, but not a standard first-line option.","evidence":"Limited"}]
Primary treatment for: Mixed anaerobic and protozoal infections
Also treats: Amoebiasis, Giardiasis, Trichomoniasis, Bacterial vaginosis
📋 Drug Information
| Generic Name(s) | Satranidazole (300mg) + Ofloxacin (200mg) |
| Brand Name | satromax o 300 mg/200 mg tablet |
| Manufacturer | Indchemie Health Specialities Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Satranidazole is a nitroimidazole that enters susceptible microorganisms and undergoes reductive activation, producing reactive intermediates that damage DNA and inhibit nucleic acid synthesis. Ofloxacin is a fluoroquinolone that inhibits DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. Together, they provide broad coverage against anaerobic bacteria and protozoa.
Mechanism Steps
💡 How to Take satromax o 300 mg/200 mg tablet
Strength: Satranidazole 300 mg + Ofloxacin 200 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet twice daily or as prescribed by your doctor. The exact dose and duration depend on the type and severity of infection, your kidney and liver function, and other medications you are taking. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects. Consult your doctor. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. Ofloxacin dose should be reduced based on creatinine clearance. Consult your doctor for specific guidance. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be needed. Monitor liver function. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is generally two tablets (Satranidazole 600 mg + Ofloxacin 400 mg) per day, but must be individualized by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of satromax o 300 mg/200 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate | |
| Caffeine | Minor | |
| Iron supplements | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Antacids containing aluminum or magnesium
- Theophylline
- NSAIDs
⚡ Moderate Interactions
- Corticosteroids
- Oral hypoglycemics
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol completely during treatment and for at least 48 hours after the last dose. Alcohol can cause a disulfiram-like reaction with Satranidazole, leading to severe nausea, vomiting, flushing, and rapid heartbeat. It may also increase the risk of liver toxicity and CNS side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Satranidazole, Ofloxacin, or other nitroimidazoles/fluoroquinolones","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Pregnancy (unless clearly needed)","Breastfeeding","Severe renal impairment (for Ofloxacin component)","Epilepsy or CNS disorders"]
⚠️ Warnings & Precautions
["Avoid alcohol during and for 48 hours after treatment.","May cause dizziness; avoid driving until you know how it affects you.","Avoid excessive sun exposure; use sunscreen.","Inform your doctor if you have kidney or liver disease.","Do not use for viral infections like common cold.","Complete the full course as prescribed.","Report any signs of tendon pain or neuropathy immediately."]
🤱 Lactation Safety
Satranidazole and Ofloxacin may pass into breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for guidance.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, dizziness, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Avoid alcohol completely during treatment and for at least 48 hours after the last dose to prevent a disulfiram-like reaction. Stay well hydrated. Avoid excessive sunlight and use sunscreen. Do not drive or operate machinery if you feel dizzy. Inform your doctor if you have kidney or liver problems, epilepsy, or tendon disorders. Do not share this medicine with others.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment may be needed. Monitor renal function closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain antibiotics or anesthetics used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting during treatment, especially if you experience dizziness or tendon pain. Consult your doctor before resuming intense activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. Take rest as needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full course even if you feel better. If you experience serious side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use may increase the risk of tendon rupture, peripheral neuropathy, and liver toxicity. Regular monitoring of liver and kidney function is advised. Use only for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Alternative combination with similar coverage.
Evidence: Well-establishedAnother alternative combination.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your doctor about recent vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines. Always carry enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but complete the full course as prescribed.
A: Inform your doctor about all medicines you take, especially antacids, warfarin, and theophylline.
A: Use only if clearly needed and prescribed by your doctor. Consult your healthcare provider.
🤔 Common Patient Concerns
🔄 Substitutes for satromax o 300 mg/200 mg tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Satrogyl-O can cure any diarrhea.
Fact: It is only effective against specific bacterial and protozoal infections. It does not treat viral diarrhea. - Myth: You can stop taking it once you feel better.
Fact: You must complete the full course to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Satranidazole + Ofloxacin combination generics
Brand Alternatives
- Satrogyl-O
- Satrogyl OZ