alzero d tablet - Levocetirizine (2.5mg) + Phenylephrine (10mg) medicine

Alzero D Tablet: Complete Medicine Guide

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🏭 Indchemie Health Specialities Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 11, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate to well-established for individual components in allergic rhinitis and nasal congestion.
Dr. Ravishankar Kumar
Medically Reviewed by Dr. Ravishankar Kumar ✓ Verified Doctor
B.A.M.S. (RMLAU Ayodhya) • Ex-Balrampur Hospital, Lucknow
Dr. Ravishankar Kumar
Clinically Verified by Dr. Ravishankar Kumar (B.A.M.S., RMLAU) — View Medical Verification Profile ↗
Clinical Background: Balrampur Hospital, Lucknow (Emergency Medicine) & SCPM Hospital | Standards: CDSCO, Indian Pharmacopoeia (IP) & WHO

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction with swelling of face, lips, or throat or difficulty breathing.
  • Chest pain, palpitations, or irregular heartbeat.
  • Severe headache with blurred vision or confusion.
  • Inability to urinate or severe lower abdominal pain.
  • Signs of hypertensive crisis such as very high blood pressure with headache and dizziness.
  • Persistent fever or worsening of symptoms after 7 days.

If experiencing severe symptoms, call emergency services immediately.

What is alzero d tablet used for?

This medicine is a combination of levocetirizine (an antihistamine) and phenylephrine (a decongestant) used to treat symptoms of allergic rhinitis, common cold, and sinusitis. It relieves sneezing, runny nose, and nasal congestion. It is usually taken once daily for up to 7 days.

  • Generic Name: Levocetirizine + Phenylephrine
  • Manufacturer: Indchemie Health Specialities Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alzero d tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी राइनाइटिस, सामान्य जुकाम और साइनसाइटिस के लक्षणों जैसे छींक, नाक बहना, नाक बंद होना और आंखों में खुजली से राहत दिलाने के लिए इस्तेमाल की जाती है। इसमें लेवोसेटिरिज़िन नामक एंटीहिस्टामिन और फेनाइलएफ्रिन नामक डिकंजेस्टेंट होता है। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द, थकान और पेट में हल्की परेशानी शामिल हैं। कुछ लोगों को बेचैनी, घबराहट या अनिद्रा भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको दिल की धड़कन तेज होना, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर सिरदर्द हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा या अवधि न बढ़ाएं। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और बढ़ सकती है। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या प्रोस्टेट की समस्या है, तो डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

alzero d tablet Uses & Benefits

Allergic rhinitis Well-established

Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.

Common cold Well-established

Provides temporary relief of nasal congestion and sneezing associated with the common cold.

Sinusitis Moderate

Helps reduce nasal congestion and pressure in acute or chronic sinusitis.

Vasomotor rhinitis Limited

May reduce nasal stuffiness and sneezing in non-allergic rhinitis.

Off-Label & Investigational Uses:

Eustachian tube dysfunction Limited (Off-label)

Sometimes used to relieve congestion and improve middle ear pressure equalization.

Otitis media with effusion Limited (Off-label)

Occasionally prescribed as an adjunct to reduce nasal congestion in children, but not routinely recommended.

Primary Treatment for: Allergic rhinitis
Also Treats:
Common cold Sinusitis Vasomotor rhinitis

📋 Drug Information

Generic Name(s)Levocetirizine + Phenylephrine
Brand NameAllercet Cold Tablet
ManufacturerIndchemie Health Specialities Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent symptom relief.
2
Avoid driving or operating heavy machinery until you know how this medicine affects your alertness.
3
Do not use this medicine for more than 7 days without consulting your doctor.
4
If you have high blood pressure or heart disease, inform your doctor before taking this medicine.
5
Stay well hydrated to help reduce dry mouth and throat irritation.
6
Report any signs of severe drowsiness, palpitations, or difficulty urinating to your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for these symptoms.
Likely Use
✅
Nasal congestion
Phenylephrine in this medicine helps relieve congestion.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Itchy, watery eyes
Levocetirizine helps relieve allergic eye symptoms.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly and extensively absorbed after oral administration. Phenylephrine is absorbed from the gastrointestinal tract but undergoes extensive first-pass metabolism, resulting in low oral bioavailability.
DistributionLevocetirizine is widely distributed throughout the body. Phenylephrine distribution is not well characterized but is expected to distribute into tissues.
Protein BindingLevocetirizine is approximately 90% bound to plasma proteins. Phenylephrine protein binding is not established from the available information.
MetabolismLevocetirizine undergoes limited metabolism, with about 14% metabolized in the liver. Phenylephrine is extensively metabolized in the gut wall and liver by monoamine oxidase and sulfotransferases.
Half-LifeThe elimination half-life of levocetirizine is approximately 6 to 8 hours in healthy adults. The elimination half-life of phenylephrine is not established from the available information.
ExcretionLevocetirizine is primarily excreted unchanged in the urine. Phenylephrine and its metabolites are excreted mainly in the urine.
BioavailabilityThe oral bioavailability of levocetirizine is high, approximately 90% or more. The oral bioavailability of phenylephrine is low and variable, estimated to be less than 40% due to first-pass metabolism.
Onset of ActionLevocetirizine begins to relieve allergic symptoms within 1 hour of oral administration. Phenylephrine nasal decongestion may begin within 15 to 30 minutes.
Peak Plasma TimeLevocetirizine reaches peak plasma concentration approximately 0.9 hours after oral administration. Phenylephrine peak plasma time is not well established but is expected within 1 to 2 hours.
Duration of ActionLevocetirizine provides relief for about 24 hours, allowing once-daily dosing. Phenylephrine decongestant effect lasts approximately 4 to 6 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Levocetirizine is a selective peripheral H1-receptor antagonist that blocks histamine from binding to H1 receptors, thereby reducing allergic symptoms such as sneezing, itching, and rhinorrhea. Phenylephrine is a direct-acting sympathomimetic amine that stimulates alpha-1 adrenergic receptors on nasal blood vessels, causing vasoconstriction and reducing nasal mucosal swelling and congestion.

Mechanism Steps

1
Histamine H1 receptor blockade: Levocetirizine binds to H1 receptors on cells in the respiratory tract and blood vessels, preventing histamine from triggering allergic responses.
2
Reduction of allergic mediators: By blocking H1 receptors, levocetirizine reduces the release of inflammatory mediators and decreases capillary permeability, leading to less sneezing, itching, and runny nose.
3
Alpha-1 adrenergic stimulation: Phenylephrine stimulates alpha-1 receptors on nasal blood vessels, causing them to constrict.
4
Nasal decongestion: Vasoconstriction reduces blood flow to the nasal mucosa, decreasing swelling and congestion, which makes breathing easier.

💡 How to Take alzero d tablet

Strength: Tablet containing levocetirizine 2.5 mg and phenylephrine 10 mg.

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Do not crush, chew, or break the tablet.
4Take it at the same time each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once daily, preferably in the evening, or as directed by your physician. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dry mouth, and urinary retention. Use with caution and consider dose reduction based on renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with moderate renal impairment (creatinine clearance 30-50 mL/min), a lower dose may be required. In severe renal impairment (creatinine clearance < 30 mL/min), use is not recommended. Consult your doctor for dose adjustment.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution in patients with severe liver disease. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (levocetirizine 2.5 mg + phenylephrine 10 mg). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid
May increase drug levels and side effects.
Alcohol
Avoid
Increases drowsiness and impairs alertness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alzero d tablet

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Consult your doctor if it persists.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugarless gum. Consult your doctor if it becomes bothersome.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, contact your doctor.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.
Nervousness (Uncommon (1-5%))
Try relaxation techniques. If it continues, speak to your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, itching, swelling of face, lips, tongue, or throat, or difficulty breathing.
Hypertensive crisis (Rare (<0.1%))
Seek immediate medical attention if you have severe headache, blurred vision, chest pain, or shortness of breath.
Cardiac arrhythmias (Rare (<0.1%))
Contact your doctor right away if you notice palpitations, irregular heartbeat, or fainting.
Urinary retention (Rare (<0.1%))
If you are unable to urinate, seek medical attention promptly.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek immediate medical advice.
Seizures
Seek emergency medical care.
Agranulocytosis
Report any signs of infection, fever, or sore throat to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
Digoxin Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., oxybutynin, benztropine)
  • Digoxin

🍷 Alcohol Interaction

Alcohol can increase drowsiness and impair mental alertness when taken with this medicine. It is advisable to avoid alcohol while using this product.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levocetirizine, phenylephrine, or any component of the formulation","Severe hypertension or uncontrolled high blood pressure","Severe coronary artery disease","Hyperthyroidism","Patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Severe renal impairment (creatinine clearance < 10 mL/min)","Children under 12 years of age"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, glaucoma, or prostate enlargement.","Do not use for more than 7 days without consulting a doctor.","May cause urinary retention; caution in patients with benign prostatic hyperplasia.","Not recommended for children under 12 years.","Consult your doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

Levocetirizine is excreted in breast milk in small amounts and may cause drowsiness in the infant. Phenylephrine may also pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, agitation, hypertension, palpitations, and difficulty urinating. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Do not drink alcohol while taking this medicine because it can increase drowsiness and impair your ability to concentrate. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or prostate enlargement. Do not use this medicine for more than 7 days without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as drowsiness, dry mouth, and urinary retention. Dose adjustment may be needed based on renal function. Use with caution and monitor blood pressure.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Levocetirizine is generally considered safe, but phenylephrine should be used with caution, especially in the first trimester.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with anesthetics and other medications. It may also affect blood pressure and heart rate.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental caries. It may also interact with local anesthetics containing epinephrine.

💚 Lifestyle Tips for Better Results

🏃
Avoid known allergens such as dust, pollen, and pet dander.
🥗
Use a humidifier to keep nasal passages moist.
😴
Stay hydrated by drinking plenty of fluids.
💧
Get adequate rest to support your immune system.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid smoking and exposure to secondhand smoke.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring mental alertness until you know how it affects you. If you experience palpitations or shortness of breath during exercise, stop and consult your doctor.

🥗 Diet Recommendations

Include foods rich in vitamin C to support immune health.
Avoid spicy foods that may irritate the throat.
Limit caffeine as it may increase nervousness.
Stay well hydrated with water and warm fluids.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring focus. It is best to take it in the evening if it makes you sleepy. Inform your employer if your job involves operating heavy equipment.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of decongestants like phenylephrine can lead to rebound congestion. Regular monitoring of blood pressure and renal function may be necessary if used for extended periods. Always consult your doctor before using for more than 7 days.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease the need for medication.

Evidence: Well-established
Intranasal corticosteroid sprays

Effective for allergic rhinitis but require prescription.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are acutely ill with fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking your dose at the same local time as prescribed. Check customs regulations for carrying prescription medicines in your destination country. Keep it in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis
She was prescribed this medicine for sneezing and nasal congestion. She took it once daily in the evening and noticed significant relief within a few hours. She experienced mild drowsiness initially but it subsided after a few days. She was advised not to drive until she knew how it affected her.
💡 Lesson: Taking the medicine in the evening can help manage daytime drowsiness, and symptom relief is usually quick.
👤 A 50-year-old man with a common cold and sinus congestion
He used this medicine for 5 days as prescribed. His nasal congestion improved, but he experienced dry mouth and mild nervousness. He was advised to drink plenty of water and avoid caffeine. His symptoms resolved without complications.
💡 Lesson: Side effects like dry mouth and nervousness are usually mild and manageable with supportive measures.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within 1 hour, and phenylephrine may relieve congestion within 15-30 minutes.

Q: Can I take this medicine with food?

A: Yes, it can be taken with or without food. However, avoid grapefruit juice as it may increase side effects.

Q: Is it safe to drive after taking this medicine?

A: This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.

Q: Can I take this medicine if I have high blood pressure?

A: Consult your doctor first. Phenylephrine can increase blood pressure, so caution is needed.

Q: How long can I continue this medicine?

A: Do not use for more than 7 days without consulting your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alzero d tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: It should not be used for more than 7 days without medical advice due to risk of side effects.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with certain conditions like severe hypertension or those taking MAOIs.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Phenylephrine generic tablets

Brand Alternatives

  • Alzero D Tablet

📊 Comparison with Similar Medicines

MedicineCompositionOnsetDurationSedationHypertension Risk
Levocetirizine + PhenylephrineLevocetirizine 2.5 mg + Phenylephrine 10 mg1 hour24 hours for antihistamine, 4-6 hours for decongestantModerateModerate
Cetirizine + PseudoephedrineCetirizine 5 mg + Pseudoephedrine 120 mg1 hour24 hours for antihistamine, 12 hours for decongestantModerateHigh
Fexofenadine + PhenylephrineFexofenadine 60 mg + Phenylephrine 10 mg1 hour12 hours for antihistamine, 4-6 hours for decongestantLowModerate

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