alzero m syrup - Levocetirizine (2.5mg) + Montelukast (5mg) medicine

Alzero M Syrup: Complete Medicine Guide for Allergic Rhinitis and Asthma

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🏭 Indchemie Health Specialities Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination syrup evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe rash or blistering skin
  • Yellowing of skin or eyes (jaundice)
  • Dark urine or severe abdominal pain
  • Unusual mood changes, agitation, or suicidal thoughts
  • Seizures or loss of consciousness
  • Severe drowsiness or confusion

If experiencing severe symptoms, call emergency services immediately.

What is alzero m syrup used for?

This medicine is a combination syrup of levocetirizine and montelukast used to treat allergic rhinitis and mild asthma. It works by blocking histamine and leukotrienes, two chemicals that cause allergy and asthma symptoms. It is taken once daily orally, usually in the evening, and should not be used as a rescue medicine for acute asthma attacks.

  • Generic Name: Levocetirizine + Montelukast
  • Manufacturer: Indchemie Health Specialities Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alzero m syrup के बारे में (Hindi Summary)

उपयोग: यह दवा लेवोसेटिरिज़िन और मॉन्टेलुकास्ट का संयोजन है, जिसका उपयोग एलर्जी राइनाइटिस (नाक की एलर्जी) और हल्के दमा के इलाज में किया जाता है। यह छींक, बहती नाक, आंखों में खुजली और नाक बंद होने जैसे लक्षणों को कम करने में मदद करती है। यह दवा एलर्जी पैदा करने वाले हिस्टामिन और ल्यूकोट्राइन को रोककर काम करती है। इसे रोजाना एक बार, आमतौर पर शाम को लिया जाता है। यह दवा अस्थमा के तीव्र दौरे के लिए राहत देने वाली दवा नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द और पेट में हल्की परेशानी शामिल हैं। कुछ लोगों में मूड बदलना, नींद में गड़बड़ी या बुरे सपने भी देखने को मिल सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको चकत्ते, सांस लेने में कठिनाई, पीलिया या मूड में गंभीर बदलाव दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से डोज न बढ़ाएं या घटाएं। इस दवा को लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अस्थमा के तीव्र दौरे के लिए इस दवा का उपयोग न करें। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alzero m syrup Uses & Benefits

[{"condition":"Allergic rhinitis (seasonal and perennial)","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion caused by allergies.","evidence":"Well-established"},{"condition":"Mild persistent asthma","description":"Helps control asthma symptoms when used with other asthma medicines, but is not for acute attacks.","evidence":"Well-established for montelukast component"},{"condition":"Exercise-induced bronchoconstriction","description":"Montelukast component may help prevent breathing difficulty triggered by exercise.","evidence":"Well-established for montelukast component"},{"condition":"Chronic urticaria (hives)","description":"Levocetirizine component helps reduce itching and hives.","evidence":"Well-established for levocetirizine component"}]

Off-label uses: [{"condition":"Sleep-related breathing problems in children with allergies","description":"Sometimes prescribed off-label when allergic rhinitis contributes to sleep-disordered breathing.","evidence":"Limited"},{"condition":"Eosinophilic bronchitis","description":"Rarely used off-label for certain inflammatory airway conditions.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Mild persistent asthma, Exercise-induced bronchoconstriction, Chronic urticaria

📋 Drug Information

Generic Name(s)Levocetirizine + Montelukast
Brand NameAllercet-M Tablet
ManufacturerIndchemie Health Specialities Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Leukotriene Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the evening, to maintain consistent levels.
2
Shake the bottle well before measuring the dose to ensure even distribution of the medicine.
3
Use the measuring cup or syringe provided with the pack; do not use a household spoon.
4
Avoid driving or operating heavy machinery until you know how this medicine affects your alertness.
5
Do not use this medicine as a rescue inhaler for sudden asthma attacks; always keep a fast-acting inhaler available.
6
Report any mood changes, sleep disturbances, or unusual behavior to your doctor immediately, especially in children.
7
Inform your doctor if you have kidney or liver problems, as dose adjustment may be needed.
8
Do not stop this medicine suddenly without consulting your doctor, especially if you are taking it for asthma.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
Itchy, watery eyes
This medicine helps relieve eye allergy symptoms.
Likely Use
Mild wheezing
This medicine may help with mild asthma symptoms but is not for acute attacks.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Severe asthma attack
This medicine is not a rescue medicine. Use a fast-acting inhaler.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevocetirizine is rapidly and almost completely absorbed after oral administration. Montelukast is also rapidly absorbed after oral administration. Food does not significantly affect the absorption of either ingredient.
DistributionLevocetirizine distributes into body tissues, and montelukast is highly bound to plasma proteins. Both ingredients cross into tissues, but specific distribution data for the combination syrup are not established from the available information.
Protein BindingLevocetirizine is about 90% bound to plasma proteins. Montelukast is more than 99% bound to plasma proteins.
MetabolismLevocetirizine is minimally metabolized in the body and is mainly excreted unchanged. Montelukast is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C8 and CYP3A4.
Half-LifeThe elimination half-life of levocetirizine is about 6 to 8 hours in adults with normal kidney function. The elimination half-life of montelukast is about 2.7 to 5.5 hours in healthy adults.
ExcretionLevocetirizine is mainly excreted unchanged in the urine. Montelukast is excreted mainly in the bile and feces, with very little excreted in urine.
BioavailabilityLevocetirizine has high oral bioavailability, close to 100%. Montelukast has an oral bioavailability of about 64% when taken without food, and food may slightly reduce it but not enough to change clinical effect.
Onset of ActionLevocetirizine starts working within 1 hour after oral intake. Montelukast may take a few days to show full effect for asthma control, but some benefit may be seen within hours for exercise-induced symptoms.
Peak Plasma TimeLevocetirizine reaches peak plasma levels about 0.9 hours after oral intake. Montelukast reaches peak plasma levels about 3 to 4 hours after oral intake.
Duration of ActionLevocetirizine provides symptom relief for about 24 hours, allowing once-daily dosing. Montelukast also provides 24-hour control of leukotriene-mediated symptoms.

How It Works

This medicine combines two active ingredients with different ways of fighting allergy and airway inflammation. Levocetirizine is a selective histamine H1-receptor antagonist that blocks histamine from attaching to its receptors, reducing sneezing, itching, and runny nose. Montelukast is a leukotriene receptor antagonist that blocks cysteinyl leukotrienes from binding to their receptors in the airways, reducing bronchoconstriction, mucus secretion, and airway swelling. Together, they address both histamine-driven and leukotriene-driven allergy symptoms.

Mechanism Steps

1
Histamine blockade by levocetirizine: Levocetirizine binds to histamine H1 receptors and prevents histamine from triggering allergy symptoms like sneezing and itching.
2
Leukotriene blockade by montelukast: Montelukast blocks cysteinyl leukotriene receptors in the airways, reducing bronchoconstriction and mucus production.
3
Combined symptom control: The two ingredients work on different allergy pathways, giving better relief of nasal and eye symptoms and helping control mild asthma.

💡 How to Take alzero m syrup

Strength: Each 5 mL of syrup contains levocetirizine 2.5 mg and montelukast 5 mg.

1Shake the bottle well before each use.
2Measure the dose using the measuring cup or syringe provided.
3Take the syrup orally, with or without food.
4If it causes stomach upset, take it with a small meal.
5Take it at the same time each day for best results.
6Do not mix with other liquids unless advised by your doctor.
7Rinse the measuring cup after each use.

Dosage Information

Adult DosageThe usual adult dose of this syrup is 5 mL to 10 mL once daily, preferably in the evening, or as prescribed by your doctor. The dose may be adjusted based on your symptoms and kidney function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 6 months of age.
Elderly DosageElderly patients may be more sensitive to the drowsiness caused by levocetirizine. Dose adjustment may be needed based on kidney function. Consult your doctor for appropriate dosing.
Renal ImpairmentIn patients with mild to moderate kidney impairment, dose adjustment may be needed. In severe kidney impairment, levocetirizine is not recommended. Consult your doctor for appropriate dosing.
Hepatic ImpairmentNo dose adjustment is needed for mild to moderate liver impairment. In severe liver impairment, use with caution and consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 10 mL of this syrup, providing levocetirizine 5 mg and montelukast 10 mg. Do not exceed this dose unless directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit juice
Limit intake
May increase levocetirizine levels slightly.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alzero m syrup

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water regularly. Consult doctor if it becomes bothersome.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Stomach pain or nausea (Uncommon (1-5%))
Take with food to reduce stomach upset. Consult doctor if it continues.
Fatigue (Uncommon (1-5%))
Get adequate rest. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical help if you notice swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Liver problems (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Mood or behavior changes (Rare (<0.1%))
Contact your doctor if you notice agitation, depression, sleep disturbances, or suicidal thoughts, especially in children.
Severe skin reactions (Very rare (<0.01%))
Seek immediate medical attention if you develop a severe rash with blisters or peeling skin.

⚠️ Rare Side Effects

Palpitations
Consult your doctor if you feel unusual heartbeats.
Seizures
Seek emergency medical help if seizures occur.
Hepatitis
Report symptoms like jaundice, dark urine, or right upper abdominal pain to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Benzodiazepines Major
Opioids Major
Rifampicin Moderate
Carbamazepine Moderate
Phenytoin Moderate
Diphenhydramine Moderate
Hydroxyzine Moderate
Theophylline Minor
Grapefruit juice Minor

🚨 Major Interactions

  • CNS depressants (e.g., benzodiazepines, opioids, alcohol)
  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)

⚡ Moderate Interactions

  • Sedating antihistamines (e.g., diphenhydramine, hydroxyzine)
  • Theophylline

🍷 Alcohol Interaction

Alcohol can increase drowsiness and dizziness caused by levocetirizine. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to levocetirizine, montelukast, or any component of this medicine","Severe kidney impairment (for levocetirizine component, dose adjustment needed)","Children under 6 months of age (for levocetirizine component)","Not for use as a rescue medicine for acute asthma attacks"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Do not use as a rescue inhaler for sudden breathing problems.","Montelukast may cause mood or behavior changes; report these to your doctor immediately.","Use with caution in patients with liver or kidney disease.","Do not exceed the prescribed dose.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Levocetirizine may pass into breast milk in small amounts and could cause drowsiness in the infant. Montelukast is generally considered safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause drowsiness, agitation, or stomach upset. Seek immediate medical attention if you suspect an overdose. Treatment is supportive and symptomatic. Contact a poison control center or emergency room right away.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor about all other medicines you take, especially sedatives, pain relievers, or blood thinners. Do not use this medicine as a rescue inhaler for sudden breathing problems. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to drowsiness and dizziness. Dose adjustment may be needed based on kidney function. Regular monitoring for side effects is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Montelukast is often considered safe for asthma control during pregnancy, but levocetirizine should be used only if clearly needed. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with sedatives used during surgery. Your doctor may advise stopping it temporarily.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene and stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergy triggers such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain a healthy weight to reduce asthma severity.
💧
Practice regular breathing exercises to improve lung function.
🧘
Get adequate sleep to support immune health.
🌞
Stay hydrated to keep airways moist.
🚭
Wash bedding regularly in hot water to reduce dust mites.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine, but if you have exercise-induced asthma, take your rescue inhaler as prescribed. Avoid strenuous exercise if you feel drowsy or dizzy. Consult your doctor before starting a new exercise routine.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds to reduce inflammation.
Eat plenty of fruits and vegetables rich in antioxidants.
Reduce intake of processed foods and added sugars.
Stay well hydrated throughout the day.
Avoid known food allergens.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause mild mood changes; report any significant changes to your doctor. Otherwise, it should not interfere with your daily work life.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like mood changes, severe allergic reactions, or liver problems, contact your doctor immediately. Your doctor may adjust or stop the medicine based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a doctor. Montelukast has been associated with rare neuropsychiatric effects, so regular follow-up is advised. Levocetirizine may cause tolerance in some patients. Periodic assessment of kidney and liver function may be needed. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to allergens can help control symptoms.

Evidence: Well-established
Nasal saline irrigation

Helps clear nasal passages and reduce congestion.

Evidence: Well-established
Immunotherapy

Allergy shots or sublingual tablets can provide long-term relief.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. You can receive vaccinations as scheduled. However, if you have a severe allergic reaction to a vaccine component, inform your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue taking it at your usual interval, but consult your doctor for specific advice. Keep enough supply for your entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with seasonal allergic rhinitis
She started this medicine as prescribed for her sneezing and runny nose during spring. Within a few days, her symptoms improved significantly. She took it in the evening and noticed mild drowsiness initially, which went away after a week. She avoided driving at night until she knew how it affected her.
💡 Lesson: Taking the medicine in the evening helps manage daytime drowsiness, and symptoms improve gradually over a few days.
👤 A 10-year-old boy with mild persistent asthma and allergic rhinitis
His doctor prescribed this syrup along with his inhaler. His parents noticed fewer asthma flare-ups and less nasal congestion. They reported mild mood changes initially, which resolved after a few weeks. Regular follow-up with the doctor helped monitor his progress.
💡 Lesson: Combination therapy can improve both asthma and allergy symptoms, but parents should watch for mood changes and report them to the doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Levocetirizine starts working within 1 hour, while montelukast may take a few days for full effect. Allergy symptoms often improve within a day, but asthma control may take longer.

Q: Can I take it at night?

A: Yes, it is often taken in the evening to minimize daytime drowsiness. Follow your doctor's instructions.

Q: Is it safe for children?

A: It is generally not recommended for children under 6 months. For older children, consult a pediatrician for appropriate dosing.

Q: Can I stop taking it suddenly?

A: Do not stop without consulting your doctor, especially if you are taking it for asthma. Sudden stopping may worsen symptoms.

Q: Does it cause drowsiness?

A: It may cause mild drowsiness in some people. Avoid driving or operating machinery until you know how it affects you.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for my child?
  • Can I take it during pregnancy?

🔄 Substitutes for alzero m syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used as a rescue inhaler for asthma attacks.
    Fact: This medicine is not a rescue medicine. It is for maintenance and prevention. Always use a fast-acting inhaler for acute attacks.
  • Myth: It is safe to take extra doses if symptoms are severe.
    Fact: Taking more than the prescribed dose can increase side effects and is not recommended.
  • Myth: This medicine is habit-forming.
    Fact: This medicine is not habit-forming and does not cause addiction.

🔄 Alternative Options

Generic Alternatives

  • Levocetirizine + Montelukast oral syrup (generic)

Brand Alternatives

  • Alzero M Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Levocetirizine + Montelukast)","composition":"Levocetirizine 2.5mg + Montelukast 5mg per 5mL","uses":"Allergic rhinitis, mild asthma","sedation":"Moderate","frequency":"Once daily"},{"medicine":"Montelukast + Cetirizine","composition":"Montelukast 5mg + Cetirizine 5mg per 5mL","uses":"Allergic rhinitis, mild asthma","sedation":"Moderate to high","frequency":"Once daily"},{"medicine":"Levocetirizine alone","composition":"Levocetirizine 2.5mg per 5mL","uses":"Allergic rhinitis, urticaria","sedation":"Low to moderate","frequency":"Once daily"}]

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