Salbuwox Syrup - Bromhexine (NA) + Salbutamol (NA) medicine

Brosmin Expectorant: Complete Medicine Guide

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🏭 Wockhardt Ltd 📦 bottle of 100 ml Syrup 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Limited to moderate for the combination; individual components have established evidence for their respective uses.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or tightness
  • Difficulty breathing or worsening breathlessness
  • Fast, irregular, or pounding heartbeat
  • Swelling of face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Blood in cough or vomit
  • Yellowing of skin or eyes
  • Severe muscle weakness or cramps

If experiencing severe symptoms, call emergency services immediately.

What is Salbuwox Syrup used for?

This medicine is a combination of bromhexine and salbutamol used to treat cough with thick mucus and wheezing. Bromhexine thins mucus, while salbutamol opens the airways. It is taken orally as prescribed by a doctor.

  • Generic Name: Bromhexine (NA) + Salbutamol (NA)
  • Manufacturer: Wockhardt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Salbuwox Syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और सालबुटामोल का संयोजन है, जिसका उपयोग गाढ़े बलगम और घरघराहट वाली खांसी के इलाज के लिए किया जाता है। ब्रोमहेक्सिन बलगम को पतला करता है, जिससे उसे खांसकर बाहर निकालना आसान हो जाता है। सालबुटामोल श्वास नलियों की मांसपेशियों को आराम देकर उन्हें फैलाता है, जिससे सांस लेने में आसानी होती है। यह दवा ब्रोंकाइटिस, अस्थमा और अन्य श्वसन रोगों में लाभकारी है, लेकिन इसका उपयोग डॉक्टर की सलाह के अनुसार ही करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और दिल की धड़कन तेज होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, तेज धड़कन या छाती में दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है, तो डॉक्टर को पहले बताएं। इस दवा के साथ शराब न लें। यदि आपको चक्कर या कंपन महसूस हो, तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को ठंडी, सूखी जगह पर रखें और बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 Salbuwox Syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps thin and loosen mucus in the airways, making it easier to cough out.","evidence":"Well-established for bromhexine as a mucolytic."},{"condition":"Acute bronchitis with wheezing","description":"Salbutamol opens the airways while bromhexine helps clear mucus, providing symptomatic relief.","evidence":"Commonly used; evidence for combination is supportive but not definitive."},{"condition":"Chronic bronchitis with bronchospasm","description":"Used to relieve breathlessness and aid mucus clearance in chronic obstructive airway conditions.","evidence":"Accepted clinical practice; combination may be used under medical supervision."},{"condition":"Asthma with thick secretions","description":"May be used as an add-on when mucus plugging is a feature, though inhaled therapy is preferred.","evidence":"Limited; not a first-line treatment for asthma."}]

Off-label uses: [{"condition":"Sinusitis with thick nasal discharge","description":"Sometimes prescribed to help thin sinus secretions, though not a standard approved use.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used to help clear middle ear fluid, but evidence is weak.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic bronchitis, Asthma with mucus plugging, COPD with thick secretions

📋 Drug Information

Generic Name(s)Bromhexine (NA) + Salbutamol (NA)
Brand NameSalbuwox Syrup
ManufacturerWockhardt Ltd
Packaging / Formbottle of 100 ml Syrup (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a cool, dry place. Protect from direct sunlight and moisture. Keep in the original container or packaging.
Shelf LifeNot established from the available information. Refer to the packaging for the expiry date.
WHO GuidelineNot established from the available information. The World Health Organization does not have specific guidelines for this fixed-dose combination.
ICMR GuidelineNot established from the available information. The Indian Council of Medical Research does not have specific guidelines for this fixed-dose combination.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine exactly as prescribed by your doctor; do not self-adjust the dose.
2
Take it with food or milk if it causes stomach upset.
3
Stay well hydrated to help loosen mucus and soothe your throat.
4
Avoid caffeine and alcohol while taking this medicine as they can worsen side effects like tremor and palpitations.
5
If you have heart disease, diabetes, or thyroid problems, inform your doctor before starting this medicine.
6
Do not use this medicine for more than the recommended duration without consulting your doctor.
7
Report any unusual symptoms such as severe palpitations, chest pain, or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing
Salbutamol helps relieve wheezing.
Likely Use
❌
Dry cough
This medicine is not for dry cough; it is for cough with mucus.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine is rapidly absorbed from the gastrointestinal tract after oral administration. Salbutamol is also well absorbed orally, though oral bioavailability is lower than inhaled due to first-pass metabolism. Specific absorption data for this fixed-dose combination are not established from the available information.
DistributionBoth bromhexine and salbutamol are widely distributed in body tissues. Bromhexine crosses the blood-brain barrier and placenta. Salbutamol crosses the placenta and is distributed into breast milk. Protein binding data for the combination are not established from the available information.
Protein BindingNot established from the available information for the combination. Bromhexine is reported to be highly protein-bound; salbutamol is approximately 10% bound.
MetabolismBromhexine undergoes extensive first-pass metabolism in the liver, primarily by cytochrome P450 enzymes. Salbutamol is metabolized in the liver mainly by sulfation to an inactive sulfate conjugate. Specific metabolic data for this combination product are not established from the available information.
Half-LifeThe elimination half-life of bromhexine is approximately 1 hour, while salbutamol has a half-life of about 4 to 6 hours. Values may vary based on individual factors.
ExcretionBromhexine and its metabolites are excreted mainly in the urine. Salbutamol is excreted primarily in the urine as unchanged drug and sulfate conjugate. Specific excretion data for the combination are not established from the available information.
BioavailabilityOral bioavailability of bromhexine is approximately 75-80% due to first-pass metabolism. Oral salbutamol bioavailability is approximately 50% due to first-pass metabolism. Data for the fixed-dose combination are not established from the available information.
Onset of ActionSalbutamol begins to act within 15-30 minutes after oral administration. Bromhexine's mucolytic effect may take a few hours to become noticeable. Onset for the combination product is not established from the available information.
Peak Plasma TimePeak plasma concentrations for bromhexine are reached in about 1 hour; for salbutamol, about 2-4 hours after oral administration. Specific data for the combination are not established from the available information.
Duration of ActionSalbutamol's bronchodilator effect lasts about 4-6 hours after oral dosing. Bromhexine's effect on mucus may last several hours. Duration for the combination product is not established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Bromhexine works as a mucolytic agent by breaking down the structure of mucus, reducing its viscosity and making it easier to expel. Salbutamol is a selective beta-2 adrenergic receptor agonist that relaxes bronchial smooth muscle, leading to bronchodilation and improved airflow. Together, they help relieve cough with thick mucus and associated wheezing or breathlessness.

Mechanism Steps

1
Bromhexine thins mucus: Bromhexine breaks down acidic mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
2
Improved mucus clearance: Thinner mucus is easier for the cilia and cough reflex to move out of the airways.
3
Salbutamol binds beta-2 receptors: Salbutamol selectively stimulates beta-2 adrenergic receptors on bronchial smooth muscle cells.
4
Bronchodilation: Receptor activation increases cyclic AMP, causing the smooth muscle to relax and the airways to widen.
5
Combined symptom relief: The two actions together reduce cough effort and ease breathing in conditions with mucus and bronchospasm.

💡 How to Take Salbuwox Syrup

Strength: Not established from the available information. Refer to the product packaging for specific strengths.

1Read the label and follow your doctor's instructions carefully.
2Take this medicine orally with a glass of water.
3It can be taken with or without food, but taking it with food may reduce stomach upset.
4Do not crush, chew, or break the medicine unless instructed by your doctor.
5Use a measuring cup or spoon if the product is a liquid, to ensure accurate dosing.
6Do not take more than the prescribed dose.
7If you miss a dose, follow the missed dose instructions.
8Store the medicine properly and keep it out of reach of children.

Dosage Information

Adult DosageThe usual adult dose of this medicine is determined by the prescribing doctor based on the condition being treated, its severity, and the patient's overall health. It is typically taken two to three times a day, but the exact dose and frequency must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Follow your doctor's instructions exactly and do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the effects of salbutamol, especially cardiac effects such as palpitations and tremor. Dose adjustment may be necessary based on kidney and liver function. Use with caution and under medical supervision.
Renal ImpairmentDose adjustment may be required in patients with severe kidney impairment. Consult your doctor for individualized dosing.
Hepatic ImpairmentBromhexine is extensively metabolized in the liver. Dose adjustment may be needed in patients with severe liver disease. Consult your doctor for individualized dosing.
Maximum Daily DoseNot established from the available information. The maximum daily dose must be determined by a qualified clinician based on the patient's condition and response to treatment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine-containing beverages
Limit intake
May increase tremor and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Salbuwox Syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset. If it persists, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Tremor (shaky hands) (Common (5-10%))
Usually decreases with continued use. Avoid caffeine. Report if bothersome.
Palpitations (Uncommon (1-5%))
Report to your doctor if you feel your heart racing or pounding.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you feel faint, have chest pain, or notice a very fast or irregular pulse.
Severe hypokalemia (low potassium) (Rare (<0.1%))
Report muscle weakness, cramps, or palpitations to your doctor promptly.
Bronchospasm (paradoxical) (Rare (<0.1%))
If breathing becomes worse after taking this medicine, stop it and seek emergency care.

⚠️ Rare Side Effects

Liver enzyme elevation
Your doctor may monitor liver function if you take this medicine for a long time.
Skin rash or itching
Stop the medicine and consult your doctor if a rash appears.
Muscle cramps
Stay hydrated and report persistent cramps to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Antacids Minor
Caffeine Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase dizziness, drowsiness, and heart rate when taken with this medicine. It is advisable to avoid alcohol while using this product.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity or allergy to bromhexine, salbutamol, or any component of the formulation","Severe cardiovascular disease including severe heart failure, uncontrolled arrhythmias, or recent myocardial infarction","Severe uncontrolled hypertension","Hyperthyroidism (overactive thyroid) unless specifically advised by a doctor","Severe hepatic or renal impairment without medical supervision","Use in children below the age recommended by the prescribing doctor"]

⚠️ Warnings & Precautions

["This medicine should be used with caution in patients with heart disease, high blood pressure, or irregular heart rhythms.","Patients with diabetes may experience changes in blood sugar levels; monitor glucose regularly.","Use with caution in patients with an overactive thyroid, as salbutamol may worsen symptoms.","Avoid using this medicine for prolonged periods without medical supervision.","Do not exceed the recommended dose; higher doses increase the risk of side effects.","If you have a history of seizures, inform your doctor before taking this medicine.","This medicine may cause dizziness or tremor; avoid driving or operating machinery until you know how it affects you.","Do not use this medicine to treat acute severe asthma attacks; it is not a substitute for emergency inhalers.","Keep out of reach of children and store as directed."]

🤱 Lactation Safety

Salbutamol is excreted in breast milk in small amounts. Bromhexine may also pass into breast milk. Consult your doctor before using this medicine while breastfeeding. The benefits of breastfeeding should be weighed against the potential risks to the infant.

💊 Overdose Management

Overdose of this medicine may cause severe tachycardia, palpitations, tremor, restlessness, chest pain, and hypokalemia. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs, electrolytes, and cardiac rhythm. There is no specific antidote. Do not try to induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than recommended. If you have heart disease, high blood pressure, diabetes, an overactive thyroid, or a history of seizures, inform your doctor before starting this medicine. Avoid drinking alcohol while taking this product, as it may increase dizziness and heart rate. Do not drive or operate heavy machinery if you feel dizzy or shaky after taking this medicine. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep all follow-up appointments and tell your doctor if your symptoms do not improve within a few days or if they get worse. Do not share this medicine with anyone else, even if they have similar symptoms. Store it in a cool, dry place away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiac effects of salbutamol, such as palpitations and tremor. They may also have reduced kidney or liver function, requiring dose adjustments. Close monitoring of heart rate, blood pressure, and electrolytes is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Both bromhexine and salbutamol should be used during pregnancy only if clearly needed and prescribed by a doctor. Discuss the potential risks and benefits with your healthcare provider.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. Salbutamol can affect heart rate and blood pressure, which may be relevant during and after surgery. Your doctor will advise whether to continue or temporarily stop the medicine.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, especially if you have heart conditions. Salbutamol may interact with certain medications used in dental procedures, such as local anesthetics containing epinephrine. Your dentist may take precautions.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water to help thin mucus.
🥗
Avoid smoking and exposure to secondhand smoke.
😴
Use a humidifier at home to keep airways moist.
💧
Practice deep breathing exercises to improve lung function.
🧘
Get adequate rest to help your body recover.
🌞
Avoid known allergens that trigger your respiratory symptoms.

🏋️ Exercise Considerations

Avoid strenuous exercise while you are unwell, especially if you have breathlessness or wheezing. Gentle walking and breathing exercises may be beneficial once symptoms improve. Consult your doctor before resuming intense physical activity.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas to soothe the throat.
Eat a balanced diet rich in fruits and vegetables to support immunity.
Avoid cold, sugary, and processed foods that may worsen mucus.
Limit caffeine intake as it can increase tremor and palpitations.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, tremor, or palpitations, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to rest and recover fully before returning to strenuous work.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any serious side effects such as severe palpitations, chest pain, or allergic reactions. Do not stop suddenly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision may lead to tolerance to salbutamol, increased risk of cardiac side effects, and electrolyte imbalances such as low potassium. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. It should not be used as a substitute for proper diagnosis and treatment of underlying respiratory conditions. Consult your doctor for periodic review if long-term therapy is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways naturally.

Evidence: Commonly used; limited clinical evidence.
Saline nasal irrigation

Can help clear nasal congestion and mucus.

Evidence: Well-established for nasal symptoms.
Chest physiotherapy

Techniques to help clear airway secretions.

Evidence: Well-established in respiratory care.

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccination, inform your doctor that you are taking this medicine. It is generally safe to receive vaccines while on this medicine, but follow your doctor's advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, adjust your dosing schedule gradually as advised by your doctor. Check customs regulations for carrying medicines in your destination country. Always keep enough supply for the entire trip and carry it in your hand luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick mucus
He was prescribed this medicine for a week. He took it with food as advised and drank plenty of water. By day 4, his cough became more productive and breathing felt easier. He completed the course and recovered fully.
💡 Lesson: Taking the medicine with food and staying hydrated improves tolerability and helps clear mucus.
👤 A 60-year-old woman with chronic bronchitis and wheezing
She was started on this medicine along with other treatments. She initially felt shaky and had palpitations, which reduced after a few days. Her doctor monitored her heart rate and potassium levels. She found significant relief in her breathing and cough.
💡 Lesson: Side effects like tremor and palpitations are common initially but often subside; regular monitoring is important, especially in older adults.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Salbutamol starts working within 15-30 minutes, while bromhexine's effect on mucus may take a few hours. You may notice gradual improvement in cough and breathing over a few days.

Q: Can I take this medicine with other cough medicines?

A: Do not take other cough medicines without consulting your doctor, as they may contain overlapping ingredients or interact with this medicine.

Q: Is it safe to take during pregnancy?

A: Use during pregnancy only if prescribed by your doctor. Both ingredients should be used when the potential benefit justifies the potential risk.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Salbuwox Syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is specifically for cough with thick mucus and wheezing, not for dry cough or other types.
  • Myth: It is safe to take without a prescription.
    Fact: It should only be used under medical supervision as it can cause serious side effects.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the prescribed dose increases the risk of side effects and does not improve efficacy.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Bromhexine + Salbutamol","primary_use":"Productive cough with wheezing","route":"Oral"},{"medicine":"Ambroxol + Salbutamol","active_ingredients":"Ambroxol + Salbutamol","primary_use":"Productive cough with wheezing","route":"Oral"},{"medicine":"Bromhexine alone","active_ingredients":"Bromhexine","primary_use":"Thick mucus","route":"Oral"}]

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