alphadopa l tablet - Labetalol (100mg) medicine

alphadopa l tablet

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Labetalol (100mg)
🏭 Wockhardt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is alphadopa l tablet used for?

This medicine contains Labetalol (100mg) and is used to treat CARDIAC. Competitive antagonist at both alpha-1 and beta-adrenergic receptors, reducing peripheral vascular r. Always consult your doctor before use.

  • Generic Name: Labetalol
  • Manufacturer: Wockhardt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alphadopa l tablet Uses & Benefits

Hypertension (including hypertensive emergencies), chronic stable angina, arrhythmias.

Off-label uses: Migraine prophylaxis, anxiety (off-label), thyrotoxicosis.

📋 Drug Information

Generic Name(s)Labetalol
Brand NameAlphadopa L
ManufacturerWockhardt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAlpha & beta blocker
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; bioavailability is approximately 25% due to extensive first-pass metabolism.
DistributionWidely distributed; crosses the placenta and is present in breast milk.
Protein BindingApproximately 50% bound to plasma proteins.
MetabolismExtensively metabolized in the liver primarily via glucuronidation; also undergoes first-pass metabolism.
Half-Life6-8 hours
ExcretionExcreted primarily in urine as metabolites and unchanged drug (less than 5%).
Bioavailability25%
Onset of Action1-2 hours after oral dose
Peak Plasma Time1-4 hours
Duration of Action8-12 hours

How It Works

Competitive antagonist at both alpha-1 and beta-adrenergic receptors, reducing peripheral vascular resistance and cardiac output.

Mechanism Steps

1Binds to alpha-1 adrenergic receptors on vascular smooth muscle, causing vasodilation and reduced peripheral resistance.
2Binds to beta-1 adrenergic receptors in the heart, reducing heart rate and contractility.
3Binds to beta-2 adrenergic receptors in bronchial and vascular smooth muscle, but effect is minimal due to alpha blockade.
4Net effect: decreased blood pressure without significant reflex tachycardia.

💡 How to Take alphadopa l tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of alphadopa l tablet

✅ Common Side Effects

Fatigue
Dizziness
Nausea
Headache
Scalp tingling
Nasal congestion

🚨 Serious Side Effects

Bradycardia
Heart failure
Bronchospasm
Hepatotoxicity
Severe hypotension

⚠️ Rare Side Effects

Lupus-like syndrome
Peyronie's disease
Positive ANA titers
Rash

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Verapamil Major Increased risk of bradycardia and heart block
Insulin Moderate Masking of hypoglycemic symptoms
NSAIDs Moderate Reduced antihypertensive effect
Cimetidine Minor Increased labetalol levels

🚨 Major Interactions

  • Beta-blockers
  • Calcium channel blockers (verapamil, diltiazem)
  • MAO inhibitors
  • Volatile anesthetics

⚡ Moderate Interactions

  • Insulin
  • Oral hypoglycemics
  • NSAIDs
  • Digoxin
  • Clonidine

🍷 Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Bronchial asthma, overt cardiac failure, cardiogenic shock, severe bradycardia, heart block greater than first degree, severe hypotension, hypersensitivity to labetalol.

🤱 Lactation Safety

Present in breast milk; use with caution, monitor infant for bradycardia and hypotension.

💊 Overdose Management

Gastric lavage, activated charcoal; symptomatic treatment: atropine for bradycardia, vasopressors for hypotension, bronchodilators for bronchospasm.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

🔄 Substitutes for alphadopa l tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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