Roxivista 50mg Suspension - Roxithromycin (50mg) medicine

Atrox 50mg Tablet DT (Roxithromycin) - Complete Medicine Guide

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🏭 Cadila Pharmaceuticals Ltd 📦 bottle of 30 ml Suspension 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Yellowing of skin or eyes, dark urine
  • Severe abdominal pain or persistent diarrhea
  • Palpitations, dizziness, or fainting
  • Signs of liver problems (nausea, loss of appetite, jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is Roxivista 50mg Suspension used for?

This medicine is a macrolide antibiotic containing Roxithromycin 50mg. It is used to treat bacterial infections of the respiratory tract, skin, and genital tract. It works by stopping bacterial growth. Take it exactly as prescribed by your doctor.

  • Generic Name: Roxithromycin (50mg)
  • Manufacturer: Cadila Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Roxivista 50mg Suspension के बारे में (Hindi Summary)

उपयोग: यह दवा रोक्सिथ्रोमाइसिन 50mg युक्त एक एंटीबायोटिक है। इसका उपयोग श्वसन तंत्र, त्वचा और जननांगों के जीवाणु संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया के विकास को रोककर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव जैसे एलर्जी, लिवर की समस्या या दिल की धड़कन में बदलाव दुर्लभ हैं। यदि आपको गंभीर लक्षण दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बेहतर महसूस होने पर भी कोर्स पूरा करें। अन्य दवाओं के बारे में डॉक्टर को बताएं। शराब से बचें। लिवर या किडनी की समस्या हो तो डॉक्टर को बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Roxivista 50mg Suspension Uses & Benefits

[{"condition":"Acute bronchitis","description":"Used to treat bacterial bronchitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Effective against common respiratory pathogens including Streptococcus pneumoniae and Mycoplasma pneumoniae.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Treats bacterial throat infections, especially when penicillin cannot be used.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Used for acute bacterial sinusitis.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective for infections such as cellulitis, folliculitis, and impetigo.","evidence":"Well-established"},{"condition":"Urethritis and cervicitis","description":"Used for infections caused by Chlamydia trachomatis and Ureaplasma urealyticum.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, though not a first-line agent.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used as an alternative in early Lyme disease, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Skin infections, Genital tract infections

📋 Drug Information

Generic Name(s)Roxithromycin (50mg)
Brand NameRoxivista 50mg Suspension
ManufacturerCadila Pharmaceuticals Ltd
Packaging / Formbottle of 30 ml Suspension (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course even if you feel better.
3
Avoid alcohol while taking this medicine.
4
Inform your doctor if you have liver or heart problems.
5
Do not share this medicine with others.
6
Report any unusual symptoms like palpitations or yellowing of eyes.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Cough with fever
This medicine is commonly prescribed for bacterial respiratory infections.
Likely Use
Skin redness and swelling
Used for bacterial skin infections.
Likely Use
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly affect the overall extent.
DistributionThis medicine distributes widely into body tissues and fluids, including lung tissue, tonsils, and prostate. It achieves high concentrations in phagocytes and is transported to sites of infection.
Protein BindingApproximately 96% bound to plasma proteins, primarily to alpha-1-acid glycoprotein and albumin.
MetabolismThis medicine is metabolized in the liver, primarily by cytochrome P450 enzymes, though to a lesser extent than erythromycin. It undergoes extensive first-pass metabolism.
Half-LifeThe elimination half-life is approximately 10 to 12 hours, allowing for once or twice daily dosing.
ExcretionThis medicine is excreted mainly in the feces via bile, with a smaller portion excreted in the urine.
BioavailabilityThe oral bioavailability of this medicine is approximately 50% to 55%.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are reached approximately 1.5 to 2 hours after oral administration.
Duration of ActionThe duration of action is approximately 12 to 24 hours, depending on the dose and the susceptibility of the organism.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This action is primarily bacteriostatic, meaning it stops bacteria from multiplying, allowing the body's immune system to clear the infection. It is effective against a range of gram-positive and atypical bacteria.

Mechanism Steps

1
Binding to ribosome: This medicine binds reversibly to the 50S subunit of the bacterial ribosome.
2
Inhibition of protein synthesis: It blocks the translocation step of protein synthesis, preventing the formation of new peptide bonds.
3
Bacterial growth arrest: Without protein synthesis, bacteria cannot grow or multiply, and are eventually cleared by the immune system.

💡 How to Take Roxivista 50mg Suspension

Strength: Dispersible tablet, 50 mg

1Disperse the tablet in a small amount of water before taking.
2Take with or without food.
3Swallow the dispersed medicine completely.
4Take at evenly spaced intervals.
5Complete the full course as prescribed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150 mg twice daily or 300 mg once daily, depending on the type and severity of the infection. For severe infections, the dose may be increased to 300 mg twice daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal and hepatic function. Consult a doctor.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <30 mL/min), dose reduction may be necessary. Consult a doctor.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose reduction or avoidance may be necessary. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 600 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid large amounts
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Roxivista 50mg Suspension

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, seek medical attention.
Abdominal pain (Common (5-10%))
Usually resolves on its own. If pain is severe, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if headache is persistent or severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Liver toxicity (hepatitis, cholestatic jaundice) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
QT prolongation and arrhythmias (Rare (<0.1%))
Seek medical attention if you experience palpitations, dizziness, or fainting.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
If you develop severe, persistent diarrhea, contact your doctor. Do not self-treat with anti-diarrheal medicines.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you experience severe upper abdominal pain radiating to the back.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.
Seizures
Seek emergency care if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergotamine Major
Terfenadine Major
Simvastatin Major
Carbamazepine Moderate
Cyclosporine Moderate
Digoxin Moderate
Theophylline Moderate
Antacids Minor
Oral contraceptives Minor

🚨 Major Interactions

  • Ergot alkaloids (e.g., ergotamine, dihydroergotamine)
  • Terfenadine, astemizole, cisapride
  • Warfarin
  • Statins (e.g., simvastatin, atorvastatin)

⚡ Moderate Interactions

  • Carbamazepine
  • Cyclosporine
  • Digoxin
  • Theophylline

🍷 Alcohol Interaction

Alcohol may increase the risk of liver side effects and stomach upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to roxithromycin or other macrolide antibiotics","Severe liver disease","Concomitant use with ergot alkaloids","Concomitant use with terfenadine, astemizole, or cisapride"]

⚠️ Warnings & Precautions

["Use with caution in patients with liver disease.","Use with caution in patients with kidney disease.","May cause QT prolongation; use with caution in patients with heart conditions.","Do not use for viral infections.","Complete the full course as prescribed.","Inform your doctor if you are pregnant or breastfeeding."]

🤱 Lactation Safety

This medicine is excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and hearing loss. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better. Inform your doctor about all other medicines you are taking, especially blood thinners, ergot alkaloids, and certain heart medicines. Avoid alcohol while taking this medicine. If you have liver or kidney problems, your doctor may need to adjust your dose. Do not share this medicine with others.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects and drug interactions. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Use effective contraception if advised.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications or affect healing.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to help your body fight the infection.
🥗
Stay well hydrated by drinking water and fluids.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Avoid alcohol and smoking.
🧘
Practice good hygiene to prevent spreading infections.

🏋️ Exercise Considerations

If you experience dizziness or fatigue, avoid strenuous exercise or operating machinery until you feel better.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Avoid spicy and oily foods if you have stomach upset.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it usually does not significantly impact daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance and rare liver or heart side effects. It is usually prescribed for short durations. Regular monitoring may be needed if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Rest and hydration

Supports the body's immune system during infection.

Evidence: Well-established
Probiotics

May help prevent antibiotic-associated diarrhea.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics do not interfere with vaccines. However, if you are acutely ill, consult your doctor about timing of vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually under medical advice. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for 7 days. He took it regularly with food and completed the course. His cough and fever improved within 3 days. He experienced mild nausea initially, which subsided after taking it with meals.
💡 Lesson: Taking the medicine with food reduces stomach upset and completing the course ensures full recovery.
👤 A 28-year-old woman with skin infection
She was prescribed this medicine for cellulitis. She noticed improvement in redness and swelling after 2 days. She was advised to avoid alcohol and to report any unusual symptoms. She completed the 10-day course and the infection resolved completely.
💡 Lesson: Adhering to the prescribed duration and avoiding alcohol helps in effective treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Roxivista 50mg Suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.

🔄 Alternative Options

Generic Alternatives

  • Roxithromycin 50mg dispersible tablet

Brand Alternatives

  • Atrox 50mg Tablet DT

📊 Comparison with Similar Medicines

[{"medicine":"Roxithromycin","class":"Macrolide","half_life":"10-12 hours","typical_dose":"150-300 mg daily"},{"medicine":"Azithromycin","class":"Macrolide","half_life":"68 hours","typical_dose":"500 mg day 1, then 250 mg days 2-5"},{"medicine":"Clarithromycin","class":"Macrolide","half_life":"3-4 hours","typical_dose":"250-500 mg twice daily"}]

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