Amide 200mg Tablet (Amisulpride): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- High fever with severe muscle stiffness, confusion, or sweating (possible neuroleptic malignant syndrome).
- Palpitations, fainting, or shortness of breath (possible heart rhythm problem).
- Involuntary movements of the face, tongue, or limbs (possible tardive dyskinesia).
- Sudden swelling of the face, lips, or throat, or difficulty breathing (severe allergic reaction).
- Unusual tiredness, fever, sore throat, or easy bruising (possible blood disorder).
- Seizures or loss of consciousness.
- Severe abdominal pain, nausea, or vomiting.
- Yellowing of the skin or eyes (jaundice).
If experiencing severe symptoms, call emergency services immediately.
What is restpride 200 tablet used for?
This medicine contains Amisulpride 200 mg, an atypical antipsychotic used to treat schizophrenia and acute psychotic episodes. It works by blocking dopamine D2 and D3 receptors in the brain, helping reduce hallucinations, delusions, and agitation. It is a prescription-only medicine and must be taken under psychiatric supervision.
- Generic Name: Amisulpride (200mg)
- Manufacturer: Matias Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 restpride 200 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एमिसलप्राइड 200 मिलीग्राम की गोली है, जिसका उपयोग मुख्य रूप से सिज़ोफ्रेनिया और अन्य मानसिक विकारों के इलाज में किया जाता है। यह मतिभ्रम, भ्रम, और अत्यधिक उत्तेजना जैसे लक्षणों को कम करने में मदद करती है। यह मस्तिष्क में डोपामिन रिसेप्टर्स को ब्लॉक करके काम करती है। यह दवा केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए और मनोचिकित्सक की देखरेख में ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे नींद आना, चक्कर आना, मुँह सूखना, कब्ज, वजन बढ़ना, और प्रोलैक्टिन हार्मोन का बढ़ना। कभी-कभी मांसपेशियों में अकड़न, कंपन, या बेचैनी हो सकती है। गंभीर दुष्प्रभाव जैसे तेज बुखार, मांसपेशियों में कड़ापन, और बेहोशी होने पर तुरंत डॉक्टर से संपर्क करें। दिल की धड़कन में बदलाव भी हो सकता है, इसलिए नियमित जांच जरूरी है।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे लक्षण वापस आ सकते हैं। शराब का सेवन बिल्कुल न करें। गाड़ी चलाने या मशीन चलाने से बचें जब तक कि आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। नियमित रूप से वजन, ब्लड शुगर, और दिल की जांच कराते रहें। दवा को ठंडी और सूखी जगह पर, बच्चों की पहुंच से दूर रखें।
💊 restpride 200 tablet Uses & Benefits
[{"condition":"Schizophrenia","description":"This medicine is used to treat positive symptoms such as hallucinations and delusions, as well as negative symptoms such as social withdrawal and lack of motivation, in patients with schizophrenia.","evidence":"Well-established"},{"condition":"Acute psychotic episodes","description":"It is used for short-term control of acute agitation, aggression, and disorganized behaviour in psychotic disorders.","evidence":"Well-established"},{"condition":"Maintenance therapy in chronic schizophrenia","description":"Lower doses are used long-term to prevent relapse of psychotic symptoms and to maintain stability.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Treatment-resistant depression","description":"Sometimes used as an add-on treatment in severe depression when standard antidepressants are not effective.","evidence":"Limited"},{"condition":"Dysthymia","description":"Low-dose Amisulpride has been studied for persistent mild depression, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Anxiety disorders","description":"Occasionally used off-label for severe anxiety, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Acute psychotic episodes, Chronic schizophrenia maintenance, Treatment-resistant depression (off-label), Dysthymia (off-label)
📋 Drug Information
| Generic Name(s) | Amisulpride (200mg) |
| Brand Name | restpride 200 tablet |
| Manufacturer | Matias Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Atypical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the tablets in their original blister pack or container. Do not remove the desiccant if present. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. The World Health Organization does not provide specific recommendations for Amisulpride in its essential medicines list. Treatment should follow local psychiatric guidelines. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has not published specific guidelines for Amisulpride. Clinicians should follow standard psychiatric practice and local protocols. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Amisulpride works by selectively blocking dopamine D2 and D3 receptors in the brain. At low doses, it preferentially blocks presynaptic D2/D3 autoreceptors, which increases dopamine release in some brain areas and may help with negative symptoms. At higher doses, it blocks postsynaptic D2/D3 receptors in the limbic system, which reduces positive psychotic symptoms such as hallucinations and delusions. It has little effect on serotonin, histamine, or muscarinic receptors, which is why it causes fewer anticholinergic and sedative effects than some other antipsychotics. However, it can increase prolactin levels because it blocks dopamine receptors in the pituitary gland.
Mechanism Steps
💡 How to Take restpride 200 tablet
Strength: Amisulpride 200 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for acute psychotic episodes is 400 mg to 800 mg per day, divided into two doses, depending on the severity of symptoms. For negative symptoms, lower doses of 50 mg to 300 mg per day may be used. The 200 mg tablet is often used as part of a higher-dose regimen. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially sedation, dizziness, and heart rhythm changes. Lower starting doses are recommended, and dose increases should be made slowly. Renal function should be checked before starting treatment, as age-related decline in kidney function can lead to drug accumulation. Regular monitoring for falls, confusion, and cardiac effects is advised. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For patients with creatinine clearance between 30 and 60 mL/min, the dose should be reduced to one-third to one-half of the usual dose. For creatinine clearance between 10 and 30 mL/min, the dose should be reduced to one-quarter to one-third of the usual dose. This medicine is contraindicated in severe renal impairment with creatinine clearance less than 10 mL/min. Always consult your doctor for personalized dosing. |
| Hepatic Impairment | Amisulpride undergoes minimal liver metabolism, so dose adjustment is generally not required in patients with mild to moderate liver impairment. However, caution is advised in severe liver disease, and patients should be monitored for side effects. Consult your doctor for personalized advice. |
| Maximum Daily Dose | The maximum recommended daily dose is 1200 mg per day, but doses above 800 mg per day are rarely used and require close monitoring. The usual maximum for most patients is 800 mg per day. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of restpride 200 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Haloperidol | Major | |
| Amiodarone | Major | |
| Levodopa | Major | |
| Alcohol | Major | |
| Antihypertensives | Moderate | |
| Benzodiazepines | Moderate | |
| Metoclopramide | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor | |
| Warfarin | Minor |
🚨 Major Interactions
- Other antipsychotics (e.g., haloperidol, risperidone)
- Drugs that prolong QT interval (e.g., amiodarone, sotalol, methadone)
- Levodopa and dopamine agonists
- Alcohol
⚡ Moderate Interactions
- Antihypertensives
- CNS depressants (e.g., benzodiazepines, opioids)
- Metoclopramide
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine. Combining them can increase sedation, dizziness, and the risk of dangerous heart rhythm changes. It can also worsen the underlying psychiatric condition and reduce the effectiveness of treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to Amisulpride or any component of the tablet","Phaeochromocytoma (a tumour of the adrenal gland)","Prolactin-dependent tumours such as pituitary prolactinoma or breast cancer","Severe renal impairment (creatinine clearance less than 10 mL/min)","Pre-existing QT prolongation or congenital long QT syndrome","Concurrent use with drugs known to prolong QT interval","Severe central nervous system depression or coma","Children below 15 years of age (safety and efficacy not established)"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.","Do not stop this medicine suddenly without consulting your doctor, as it can cause withdrawal symptoms or relapse.","Use with caution in patients with a history of seizures, Parkinson's disease, or cardiovascular disease.","Monitor for signs of neuroleptic malignant syndrome, such as high fever, muscle rigidity, and altered consciousness.","Regular monitoring of blood sugar, lipids, and weight is recommended because antipsychotics can cause metabolic changes.","Elderly patients with dementia-related psychosis are at increased risk of stroke and death when treated with antipsychotics; this medicine should be used with caution in this group.","Avoid alcohol and other central nervous system depressants while taking this medicine.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Keep all follow-up appointments for monitoring of heart rhythm, blood tests, and mental health."]
🤱 Lactation Safety
Amisulpride is excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless the benefits clearly outweigh the risks. Consult your doctor to discuss alternative options or formula feeding.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, low blood pressure, abnormal heart rhythms, and extrapyramidal symptoms. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include monitoring of vital signs, ECG, and electrolyte levels. There is no specific antidote. Activated charcoal may be considered if the patient presents early. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop it suddenly, because stopping abruptly can cause withdrawal symptoms or a relapse of psychosis. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not drink alcohol while taking this medicine, as it can worsen sedation and affect your heart rhythm. Tell your doctor if you have kidney problems, heart problems, epilepsy, Parkinson's disease, or a history of blood clots. Inform your doctor about all other medicines you take, including over-the-counter drugs and herbal supplements. If you are pregnant, planning pregnancy, or breastfeeding, discuss the risks and benefits with your doctor before continuing this medicine. Keep all follow-up appointments so your doctor can monitor your symptoms, weight, blood sugar, prolactin levels, and heart rhythm. Store this medicine in its original packaging, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of this medicine, especially sedation, dizziness, low blood pressure, and heart rhythm changes. They are also at higher risk of falls and fractures. Lower starting doses and slow titration are recommended. Renal function should be assessed before starting treatment, as age-related decline in kidney function can lead to drug accumulation. Regular monitoring for confusion, extrapyramidal symptoms, and cardiac effects is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this with your psychiatrist before conception. There are limited data on the safety of this medicine in pregnancy. Your doctor may consider switching to an alternative antipsychotic with a better safety profile, or adjusting the dose. Do not stop this medicine suddenly on your own, as this can cause relapse. Use effective contraception while taking this medicine unless you are planning a pregnancy under medical guidance.
🏥 Post-Surgery Considerations
Inform your surgeon and anaesthesiologist that you are taking this medicine before any surgery. It can interact with anaesthetic agents and other medications used during surgery, increasing the risk of sedation, low blood pressure, and heart rhythm problems. Your doctor may advise you to temporarily stop or adjust the dose before surgery. Do not make any changes without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can cause dry mouth, which may increase the risk of dental problems. It can also interact with local anaesthetics and sedatives used during dental work. Your dentist may take extra precautions and monitor your vital signs. Maintain good oral hygiene and regular dental check-ups.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and low blood pressure, especially when starting treatment or increasing the dose. Avoid strenuous exercise or activities that require alertness until you know how it affects you. If you feel dizzy or faint during exercise, stop immediately and sit down. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause sedation, dizziness, and difficulty concentrating, especially during the first few weeks of treatment. Avoid driving, operating heavy machinery, or performing tasks that require full alertness until you know how it affects you. Inform your employer about your condition and any necessary accommodations. With stable treatment, many people are able to return to work and lead productive lives.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects such as neuroleptic malignant syndrome, severe allergic reactions, or heart rhythm problems, seek immediate medical attention. Your doctor may decide to stop or change the medicine based on your response, side effects, or other health conditions. Gradual dose reduction is usually recommended to avoid withdrawal symptoms and relapse.
📅 Long-Term Use Effects
Long-term use of this medicine may be associated with tardive dyskinesia, a condition involving involuntary movements of the face, tongue, or limbs. Regular monitoring for this is essential. It can also cause weight gain, metabolic changes, and raised prolactin levels, which may affect hormonal balance. Periodic blood tests, ECG, and clinical reviews are recommended to detect any problems early. The benefits of long-term treatment in preventing relapse generally outweigh the risks when used under proper medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage psychotic symptoms and improve coping skills when used alongside medication.
Evidence: Well-establishedInvolving family in treatment can improve outcomes and reduce relapse rates.
Evidence: Well-establishedRegular exercise, healthy diet, and good sleep hygiene can support overall mental health.
Evidence: SupportiveHelps patients return to work or find employment, improving quality of life.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccination, inform your healthcare provider that you are taking this medicine. Routine vaccinations can generally be administered safely, but live vaccines should be avoided if your immune system is compromised.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original blister pack or container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep enough supply for the entire trip, plus extra in case of delays. Store it in a cool, dry place, away from direct sunlight. If crossing time zones, consult your doctor about adjusting the timing of doses. Carry a medical alert card stating your condition and medicines. Check customs regulations for controlled substances before travelling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some improvement in symptoms may be noticed within a few days, but full therapeutic effect usually takes 1 to 2 weeks or longer. It is important to continue taking it as prescribed.
A: No, you should not stop suddenly. Stopping abruptly can cause withdrawal symptoms or a relapse of psychosis. Always consult your doctor before making any changes.
A: Weight gain is a common side effect of many antipsychotics, including this medicine. Regular monitoring of weight and a healthy lifestyle can help manage it. Consult your doctor if you notice significant weight gain.
A: There are limited data on its safety in pregnancy. It should only be used if the benefits clearly outweigh the risks, as advised by your doctor. Discuss your pregnancy plans with your psychiatrist.
A: No, alcohol should be strictly avoided. It can increase sedation, dizziness, and the risk of heart rhythm problems.
🤔 Common Patient Concerns
🔄 Substitutes for restpride 200 tablet
View AllAlternative brands with exact same active ingredient:
-
absull 200 tablet srAbseil Pharmaceticals Pvt Ltd ₹115.00 42.2% CHEAPER
-
stayhappi amisulpride 200mg tabletSarvagunaushdhi Pvt Ltd ₹126.56 36.4% CHEAPER
-
trikosul 200mg tabletTriko Pharmaceuticals ₹133.93 32.7% CHEAPER
-
amicalm 200mg tabletTriton Healthcare Pvt Ltd ₹135.21 32.1% CHEAPER
-
cenride 200 mg tabletUSV Ltd ₹138.75 30.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Amisulpride is a sleeping pill.
Fact: Amisulpride is an antipsychotic medicine used for schizophrenia and psychosis. It is not a sleeping pill, although it can cause sedation as a side effect. - Myth: You can stop Amisulpride as soon as you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms and relapse of psychosis. Always consult your doctor before stopping. - Myth: Amisulpride is addictive.
Fact: Amisulpride does not cause addiction in the way that drugs of abuse do. However, it should only be used under medical supervision. - Myth: Amisulpride is safe to take during pregnancy without any risk.
Fact: There are limited data on its safety in pregnancy. It should only be used if the benefits clearly outweigh the risks, as advised by your doctor.
🔄 Alternative Options
Generic Alternatives
- Amisulpride 200 mg tablet (various manufacturers)
Brand Alternatives
- Amide 200mg Tablet