arotine 25mg tablet cr - Paroxetine (25mg) medicine

arotine 25mg tablet cr - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Matias Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is arotine 25mg tablet cr used for?

Aroximat CR 12.5 Tablet (Paroxetine) is used to treat NEURO CNS. It contains Paroxetine (25mg), which Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paroxetine
  • Manufacturer: Matias Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š arotine 25mg tablet cr Uses & Benefits

Major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, post-traumatic stress disorder.

Off-label uses: Premenstrual dysphoric disorder, hot flashes, premature ejaculation.

๐Ÿ“‹ Drug Information

Generic Name(s)Paroxetine
Brand NameAroximat CR 12.5 Tablet
ManufacturerMatias Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; food does not significantly affect absorption.
DistributionWidely distributed in the body; crosses the blood-brain barrier.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2D6 and other enzymes.
Half-LifeAbout 21 hours (range 3-65 hours).
ExcretionPrimarily excreted in urine (64%) and feces (36%).
BioavailabilityAbout 50-100% (mean 86%).
Onset of Action1-2 weeks for therapeutic effect.
Peak Plasma Time5-6 hours (controlled-release formulation).
Duration of Action24 hours.

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the synaptic cleft.

Mechanism Steps

1Paroxetine binds to the serotonin transporter (SERT) on presynaptic neurons.
2Inhibits reuptake of serotonin into the presynaptic neuron.
3Increases serotonin concentration in the synaptic cleft.

๐Ÿ’ก How to Take arotine 25mg tablet cr

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of arotine 25mg tablet cr

โœ… Common Side Effects

  • Nausea
  • Drowsiness
  • Dizziness
  • Insomnia
  • Dry mouth
  • Constipation
  • Sexual dysfunction

๐Ÿšจ Serious Side Effects

  • Serotonin syndrome
  • Suicidal thoughts
  • Bleeding
  • Seizures
  • Hyponatremia

โš ๏ธ Rare Side Effects

  • Priapism
  • Angle-closure glaucoma
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Risk of serotonin syndrome
Warfarin Moderate Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Cimetidine Moderate Increased paroxetine levels
Tamoxifen Moderate Reduced tamoxifen efficacy

๐Ÿšจ Major Interactions

  • MAOIs
  • Pimozide
  • Thioridazine
  • Linezolid
  • Methylene Blue

โšก Moderate Interactions

  • Warfarin
  • NSAIDs
  • Aspirin
  • Cimetidine
  • Flecainide
  • Propafenone
  • Tamoxifen

โ„น๏ธ Minor Interactions

  • Digoxin
  • Theophylline
  • Lithium

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase paroxetine levels.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, concurrent MAOI use, pregnancy (especially third trimester), lactation.

๐Ÿ“Š Monitoring Parameters

Suicidal ideation, serotonin syndrome symptoms, liver function, renal function.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk.

๐Ÿ’Š Overdose Management

Activated charcoal, supportive care; serotonin syndrome management.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for arotine 25mg tablet cr

View All

Alternative brands with exact same active ingredient (Paroxetine (25mg)):

Medical Note: Always consult your doctor before switching medications.

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