Anaxime-OZ Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, or difficulty breathing.
- Persistent watery diarrhea, abdominal cramps, or fever.
- Numbness, tingling, or weakness in hands or feet.
- Unusual bleeding or bruising.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain.
- Seizures or severe headache with confusion.
- Decreased urine output or swelling in legs.
If experiencing severe symptoms, call emergency services immediately.
What is Ranicef OZ 200mg/500mg Tablet used for?
This medicine is a combination antibiotic containing Cefixime and Ornidazole, used to treat mixed bacterial and anaerobic infections. It is taken orally, usually twice daily, and must be prescribed by a doctor.
- Generic Name: Cefixime (200mg) + Ornidazole (500mg)
- Manufacturer: Lemford Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Ranicef OZ 200mg/500mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम और ओर्निडाजोल का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह टाइफाइड, मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, पेट के अंदर के संक्रमण, स्त्री रोग संबंधी संक्रमण और दांतों के संक्रमण में प्रभावी है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और भूख में कमी शामिल हैं। कुछ लोगों को मुंह में धातु जैसा स्वाद, सिरदर्द या चक्कर आ सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, या हाथ-पैरों में झुनझुनी हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कोर्स पूरा करें, बीच में न छोड़ें। दवा को पानी के साथ निगलें। खाने के साथ या बिना खाने के ले सकते हैं, लेकिन पेट खराब हो तो खाने के साथ लें। शराब का सेवन बिल्कुल न करें, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। गुर्दे या जिगर की बीमारी हो तो डॉक्टर को बताएं। एंटासिड या आयरन की गोलियां इस दवा से 2 घंटे पहले या बाद में लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 Ranicef OZ 200mg/500mg Tablet Uses & Benefits
[{"condition":"Typhoid fever","description":"Used to treat enteric fever caused by Salmonella typhi, especially when mixed anaerobic coverage is needed.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against many gram-negative bacteria causing uncomplicated and complicated UTIs.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for bronchitis, pneumonia, and sinusitis when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Covers both aerobic and anaerobic bacteria in conditions like peritonitis and abscesses.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Treats pelvic inflammatory disease and bacterial vaginosis with mixed flora.","evidence":"Moderate"},{"condition":"Dental infections","description":"Used for dental abscesses and periodontitis where anaerobes are involved.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prophylaxis in colorectal surgery","description":"Sometimes used to prevent surgical site infections, though not a standard approved indication.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Typhoid fever, Urinary tract infections, Respiratory tract infections, Intra-abdominal infections, Gynecological infections, Dental infections
📋 Drug Information
| Generic Name(s) | Cefixime (200mg) + Ornidazole (500mg) |
| Brand Name | Ranicef OZ 200mg/500mg Tablet |
| Manufacturer | Lemford Biotech Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with different mechanisms. Cefixime, a third-generation cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis and death. Ornidazole, a nitroimidazole, enters anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA and inhibit nucleic acid synthesis, causing cell death. This dual action provides broad coverage against both aerobic and anaerobic pathogens.
Mechanism Steps
💡 How to Take Ranicef OZ 200mg/500mg Tablet
Strength: Each film-coated tablet contains Cefixime 200 mg and Ornidazole 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet (Cefixime 200 mg + Ornidazole 500 mg) taken orally twice daily, or as directed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Cefixime is excreted by the kidneys, and renal function declines with age. Monitor renal function and adjust dose accordingly. Ornidazole dose generally does not need adjustment in the elderly unless liver function is impaired. |
| Renal Impairment | In patients with creatinine clearance between 20 and 40 mL/min, a dose reduction of Cefixime may be required. For creatinine clearance less than 20 mL/min, the dose should be further reduced or the dosing interval extended. Ornidazole does not require dose adjustment in renal impairment. Consult your doctor for specific dosing. |
| Hepatic Impairment | Ornidazole is metabolized in the liver. In patients with severe hepatic impairment, dose reduction may be necessary. Cefixime does not require dose adjustment in hepatic impairment. Monitor liver function tests periodically. |
| Maximum Daily Dose | The maximum recommended daily dose is Cefixime 400 mg and Ornidazole 1000 mg, divided into two doses. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Ranicef OZ 200mg/500mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Antacids | Moderate | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Lithium | Moderate | |
| Probenecid | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Antacids (aluminum/magnesium hydroxide)
⚡ Moderate Interactions
- Carbamazepine
- Phenytoin
- Lithium
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 48 hours after the last dose. Ornidazole can cause a disulfiram-like reaction with alcohol, leading to severe nausea, vomiting, flushing, headache, and rapid heartbeat. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cephalosporins or nitroimidazoles.","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Take the full course as prescribed, even if symptoms improve.","Avoid alcohol during and for 48 hours after treatment.","Use with caution in patients with liver disease; monitor liver function.","Adjust dose in severe renal impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have a history of seizures or neurological disorders.","Do not share this medicine with others."]
🤱 Lactation Safety
Cefixime is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding. Ornidazole also passes into breast milk. It is recommended to avoid breastfeeding during treatment and for 48 hours after the last dose to prevent potential effects on the infant. Consult your doctor for guidance.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, and neurological symptoms. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if overdose is suspected. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better, as this can lead to antibiotic resistance and relapse of infection. Swallow the tablet whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid consuming alcohol while taking this medicine and for at least 48 hours after the last dose, because Ornidazole can cause a disulfiram-like reaction with symptoms like severe nausea, vomiting, flushing, and rapid heartbeat. Inform your doctor if you have kidney or liver problems, as dose adjustments may be needed. Do not take antacids or iron supplements within 2 hours of this medicine, as they can reduce its absorption. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and are more prone to side effects. Dose adjustment may be needed based on renal function. Monitor for confusion, dizziness, and falls.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Ornidazole is not recommended in the first trimester. Use effective contraception during treatment if you are of childbearing age.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat infections. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon about any allergies.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with other medications used during dental work. Continue taking it as prescribed unless advised otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild exercise is generally safe, but if you experience dizziness or fatigue, avoid strenuous activities. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but take rest if needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, gut flora imbalance, and rare neurological effects like peripheral neuropathy. It should only be used for the prescribed duration. Regular monitoring of kidney and liver function may be needed if used for prolonged periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help maintain gut flora during antibiotic treatment.
Evidence: ModerateFor viral infections, rest and fluids are the mainstay.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics do not interfere with most vaccines. However, if you are scheduled for a live vaccine, inform your doctor about this medicine. There is no specific contraindication.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but you must complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol must be strictly avoided during treatment and for 48 hours after the last dose due to the risk of a disulfiram-like reaction.
🤔 Common Patient Concerns
🔄 Substitutes for Ranicef OZ 200mg/500mg Tablet
View AllAlternative brands with exact same active ingredient:
-
ceficacy-oz 200mg/500mg tabletDallas Pharmaceuticals and Formulations Pvt Ltd ₹11.72 92.6% CHEAPER
-
cefydoc oz 200 mg/500 mg tabletMorepen Laboratories Ltd ₹70.00 56.1% CHEAPER
-
ceffex oz tabletAtlantis Formulations Pvt Ltd ₹73.13 54.1% CHEAPER
-
Rezix OZ 200mg/500mg TabletRezicure Pharmaceuticals ₹73.13 54.1% CHEAPER
-
vexifix oz 200mg/500mg tabletVexilla Healthcare ₹77.00 51.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course to prevent recurrence and antibiotic resistance. - Myth: Alcohol is safe with all antibiotics.
Fact: Alcohol interacts with Ornidazole and can cause a serious disulfiram-like reaction.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Ornidazole 500 mg tablet (various manufacturers)
Brand Alternatives
- Anaxime-OZ Tablet