alcan 150mg/200mg tablet - Fluconazole (150mg) + Cefixime (200mg) medicine

Alcan 150mg/200mg Tablet: Complete Medicine Guide

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🏭 Allpa India Medicines Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited evidence for the combination. Individual ingredients have well-established evidence for specific indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe skin rash with blisters or peeling
  • Yellowing of the eyes or skin
  • Severe abdominal pain or bloody diarrhea
  • Irregular heartbeat or fainting
  • Decreased urine output or swelling in the legs
  • Unusual bleeding or bruising
  • Persistent high fever despite taking the medicine

If experiencing severe symptoms, call emergency services immediately.

What is alcan 150mg/200mg tablet used for?

This medicine is a prescription combination of fluconazole 150 mg and cefixime 200 mg used to treat mixed bacterial and fungal infections. It works by killing fungi and bacteria. Take it exactly as prescribed, usually with food, and complete the full course.

  • Generic Name: Fluconazole + Cefixime
  • Manufacturer: Allpa India Medicines Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alcan 150mg/200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा फ्लुकोनाज़ोल 150 मिलीग्राम और सेफिक्सिम 200 मिलीग्राम का संयोजन है। इसका उपयोग बैक्टीरिया और फंगस दोनों के कारण होने वाले मिश्रित संक्रमणों के इलाज के लिए किया जाता है। यह आमतौर पर जननांग संक्रमण, मूत्र मार्ग संक्रमण और त्वचा संक्रमण में दी जाती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में जी मिचलाना, पेट दर्द, दस्त, सिरदर्द और हल्के दाने शामिल हैं। कुछ लोगों को चक्कर आना या स्वाद में बदलाव महसूस हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे दूसरों के साथ साझा न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं, मधुमेह की दवाएं और एंटासिड। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें, चाहे आप बेहतर महसूस करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 alcan 150mg/200mg tablet Uses & Benefits

[{"condition":"Mixed bacterial and fungal genital infections","description":"Used when a clinician identifies both susceptible bacteria and fungi, such as in complicated vulvovaginitis or balanitis.","evidence":"Limited"},{"condition":"Complicated urinary tract infections with fungal involvement","description":"May be prescribed when urine culture shows both bacteria and yeast, but only under specialist guidance.","evidence":"Limited"},{"condition":"Skin and soft tissue infections with suspected mixed organisms","description":"Rarely used for mixed skin infections when both bacterial and fungal causes are suspected.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prophylaxis in immunocompromised patients","description":"Sometimes considered for preventing mixed infections in very specific high-risk patients, but not standard.","evidence":"Limited"}]

Primary treatment for: Mixed bacterial and fungal infections

Also treats: Complicated urinary tract infections, Genital infections, Skin infections

📋 Drug Information

Generic Name(s)Fluconazole + Cefixime
Brand NameAlcan 150mg/200mg Tablet
ManufacturerAllpa India Medicines Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntifungal + Antibiotic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this combination only when both bacterial and fungal infections are confirmed or strongly suspected.
2
Advise patients to take the tablet with food to reduce gastrointestinal side effects.
3
Warn patients about the risk of QT prolongation, especially if they have heart disease or take other QT-prolonging drugs.
4
Monitor liver and kidney function in patients with pre-existing organ impairment.
5
Instruct patients to complete the full course and not to stop early, even if symptoms improve.
6
Caution patients to avoid alcohol during treatment.
7
Review all concomitant medications for potential interactions, especially warfarin, sulfonylureas, and antacids.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Vaginal discharge and itching
This medicine may be prescribed for mixed infections causing these symptoms.
Likely Use
Burning urination
May be used for complicated urinary tract infections with mixed organisms.
Likely Use
Common cold
This medicine does not treat viral infections.
Not Primary
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFluconazole is well absorbed from the gastrointestinal tract after oral administration, with high bioavailability. Cefixime is also absorbed orally, but food may slightly delay absorption without reducing the total amount absorbed.
DistributionFluconazole distributes widely into body fluids and tissues, including cerebrospinal fluid and vaginal secretions. Cefixime distributes into various tissues and fluids, but its penetration into cerebrospinal fluid is limited.
Protein BindingFluconazole has low protein binding, approximately 11 to 12 percent. Cefixime is highly protein bound, approximately 65 to 70 percent.
MetabolismFluconazole undergoes minimal hepatic metabolism and is mainly excreted unchanged in urine. Cefixime is not significantly metabolized and is excreted largely unchanged.
Half-LifeFluconazole elimination half-life is approximately 30 hours in adults with normal kidney function. Cefixime elimination half-life is approximately 3 to 4 hours.
ExcretionFluconazole is primarily excreted unchanged in urine, with a small amount in feces. Cefixime is excreted mainly in urine as unchanged drug.
BioavailabilityFluconazole oral bioavailability is greater than 90 percent. Cefixime oral bioavailability is approximately 40 to 50 percent.
Onset of ActionFluconazole onset of action is gradual, often within 24 to 48 hours for susceptible fungal infections. Cefixime onset is usually within a few hours for susceptible bacterial infections.
Peak Plasma TimeFluconazole peak plasma concentration occurs about 1 to 2 hours after oral administration. Cefixime peak plasma concentration occurs about 3 to 4 hours after oral administration.
Duration of ActionFluconazole duration of action is prolonged due to its long half-life, allowing once-daily dosing. Cefixime duration of action is shorter and typically requires twice-daily dosing.

How It Works

This medicine combines two active ingredients with separate mechanisms. Fluconazole inhibits the fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking the conversion of lanosterol to ergosterol, which weakens the fungal cell membrane. Cefixime binds to penicillin-binding proteins and inhibits bacterial cell wall synthesis, leading to bacterial death. Together they target both fungal and bacterial components of a mixed infection.

Mechanism Steps

1
Fluconazole uptake by fungal cells: Fluconazole enters fungal cells and accumulates, where it interacts with its target enzyme.
2
Inhibition of ergosterol synthesis: Fluconazole blocks 14-alpha-demethylase, reducing ergosterol and disrupting the fungal cell membrane.
3
Cefixime binding to penicillin-binding proteins: Cefixime attaches to specific penicillin-binding proteins on the bacterial cell wall.
4
Inhibition of bacterial cell wall cross-linking: This prevents the formation of a stable peptidoglycan layer, causing bacterial cell lysis.
5
Combined antimicrobial effect: The two ingredients act independently to reduce both fungal and bacterial burden.

💡 How to Take alcan 150mg/200mg tablet

Strength: Tablet containing fluconazole 150 mg and cefixime 200 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take it with food to reduce stomach upset.
4Do not crush, chew, or break the tablet unless your doctor advises.
5Take it at the same time each day to maintain consistent levels.
6Complete the full course even if you feel better.
7Do not take an extra dose if you miss one. Follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, depending on the infection being treated. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of infection, age, weight, kidney function, and liver function. Do not self-adjust the dose. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may need dose adjustment based on kidney function. Fluconazole is excreted by the kidneys, and kidney function declines with age. Cefixime dose may also need adjustment. Consult your doctor for appropriate dosing.
Renal ImpairmentDose adjustment is required in patients with kidney disease. Fluconazole dose should be reduced based on creatinine clearance. Cefixime dose may also need adjustment. Consult your doctor for personalized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Fluconazole and cefixime may rarely affect the liver. Dose adjustment may be needed. Consult your doctor for personalized dosing.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. For fluconazole, the maximum adult dose is usually 400 mg per day for most indications, but higher doses may be used in specific serious infections under specialist care. For cefixime, the maximum adult dose is usually 400 mg per day. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Grapefruit
Avoid large amounts
May affect drug metabolism, but clinical significance is not well established.
Alcohol
Avoid
Increases risk of liver problems and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alcan 150mg/200mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food and drink plenty of water. Consult doctor if it persists.
Stomach pain (Common (5-10%))
Take with meals. Avoid spicy food. Consult doctor if severe.
Loose motions (Common (5-10%))
Stay hydrated. Consult doctor if diarrhea is severe or bloody.
Headache (Common (5-10%))
Rest and hydrate. Consult doctor if headache is severe or persistent.
Rash (Uncommon (1-5%))
Stop the medicine and consult your doctor immediately if rash spreads or is accompanied by fever.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you have difficulty breathing, swelling of face or throat, or a severe rash.
Liver injury (Rare (<0.1%))
Report yellowing of eyes or skin, dark urine, or severe abdominal pain to your doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Very rare (<0.01%))
Stop the medicine and go to an emergency room if you develop painful skin peeling, blisters, or sores in the mouth.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you have severe, persistent, or bloody diarrhea, even weeks after finishing the antibiotic.
Seizures (Very rare (<0.01%))
Seek emergency care if you experience convulsions or loss of consciousness.

⚠️ Rare Side Effects

Blood disorders (leukopenia, thrombocytopenia)
Report unusual bruising, bleeding, or persistent fever to your doctor.
Kidney inflammation (interstitial nephritis)
Report decreased urine output or swelling to your doctor.
Severe mood changes or hallucinations
Contact your doctor if you notice confusion, hallucinations, or severe anxiety.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Oral hypoglycemics Major
QT-prolonging drugs Major
Rifampicin Major
Tacrolimus Major
Phenytoin Moderate
Cyclosporine Moderate
Theophylline Moderate
Zidovudine Moderate
Antacids Moderate

🚨 Major Interactions

  • Warfarin
  • Oral hypoglycemics (sulfonylureas)
  • QT-prolonging drugs (e.g., amiodarone, sotalol)
  • Rifampicin
  • Tacrolimus

⚡ Moderate Interactions

  • Phenytoin
  • Cyclosporine
  • Theophylline
  • Zidovudine
  • Antacids

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver problems and may worsen side effects such as nausea and dizziness. It can also interfere with your body's ability to fight infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to fluconazole, other azole antifungals, cefixime, or other cephalosporins","Severe liver disease","Severe kidney disease (dose adjustment needed, may be contraindicated)","History of severe allergic reaction to penicillins (cross-reactivity possible)","Use with caution in patients with QT prolongation or taking QT-prolonging drugs","Pregnancy (especially high doses of fluconazole)"]

⚠️ Warnings & Precautions

["Do not use for viral infections like common cold or flu.","Complete the full course as prescribed even if you feel better.","Inform your doctor if you have liver or kidney disease.","Avoid alcohol during treatment.","Use effective contraception while taking this medicine.","Report any signs of allergic reaction immediately.","Do not share this medicine with others.","Take with food to reduce stomach upset.","If you develop severe diarrhea, consult your doctor before taking anti-diarrheal medicines.","Inform your doctor if you are taking blood thinners, diabetes medicines, or antacids."]

🤱 Lactation Safety

Fluconazole passes into breast milk in small amounts. Cefixime also passes into breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe nausea, vomiting, stomach pain, dizziness, and fainting. Treatment is supportive and symptomatic. There is no specific antidote. Fluconazole can be removed by hemodialysis. Cefixime is not significantly removed by dialysis.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others. Inform your doctor about all other medicines, especially blood thinners, diabetes medicines, and antacids. Avoid alcohol during treatment. Use effective contraception while taking this medicine. Complete the full course even if you feel better. Do not stop suddenly without medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and kidney problems. Kidney function declines with age, so dose adjustment may be needed. Monitor liver and kidney function regularly. Consult your doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Fluconazole may be harmful to the developing fetus, especially at high doses. Use effective contraception while taking this medicine. Discuss alternative treatments with your doctor if you are trying to conceive.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and doctor before taking this medicine. It may interact with other medicines used during surgery. Your doctor will assess whether it is safe to take this medicine after surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may interact with antibiotics or other medicines used during dental work. Your dentist may advise you to continue or temporarily stop the medicine based on your condition.

💚 Lifestyle Tips for Better Results

🏃
Maintain good personal hygiene to prevent reinfection.
🥗
Wear loose, cotton undergarments to reduce moisture and fungal growth.
😴
Stay well hydrated to help flush out bacteria from the urinary tract.
💧
Avoid excessive sugar intake as it can promote fungal growth.
🧘
Complete the full course of medicine even if you feel better.
🌞
Practice safe sex to prevent sexually transmitted infections.
🚭
Manage stress and get adequate sleep to support your immune system.

🏋️ Exercise Considerations

This medicine may cause dizziness in some people. Avoid heavy exercise or operating machinery if you feel dizzy. Mild to moderate exercise is generally safe. Stay hydrated during exercise.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to support gut health.
Reduce sugar and refined carbohydrate intake to limit fungal growth.
Eat plenty of fruits and vegetables for immune support.
Stay well hydrated with water and clear fluids.
Avoid alcohol and caffeine if you have stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness in some people. If you experience these effects, avoid driving or operating heavy machinery. Most people can continue their normal daily activities. Take the medicine with food to reduce stomach upset. Inform your employer if you need to take it during work hours.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects such as allergic reactions, severe diarrhea, or yellowing of the eyes, stop the medicine and seek medical attention immediately. Your doctor will advise you on when it is safe to stop.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of liver and kidney problems, fungal resistance, and vitamin deficiencies. It should only be used for the prescribed duration. If long-term therapy is needed, your doctor will monitor your liver and kidney function regularly. Do not self-medicate for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal and antibacterial creams

For localized skin or genital infections, topical treatments may be used instead of oral medicines.

Evidence: Well-established
Probiotics

May help restore healthy bacteria and prevent fungal overgrowth, especially after antibiotic use.

Evidence: Limited
Good hygiene practices

Keeping the affected area clean and dry can help prevent and manage infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with most vaccines. However, if you are scheduled for a live vaccine, inform your doctor as antibiotics may affect the vaccine's effectiveness. There is no specific contraindication for vaccines with this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. Store at room temperature and protect from direct sunlight. If crossing time zones, continue your regular dosing schedule as prescribed. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with recurrent vaginal discharge and itching
She was diagnosed with a mixed bacterial and fungal infection. Her doctor prescribed this medicine twice daily with food. She noticed improvement in discharge and itching within 3 days. She completed the 7-day course as advised and avoided alcohol. She also used a topical cream for external itching.
💡 Lesson: Taking the medicine with food reduced her stomach upset, and completing the full course prevented recurrence.
👤 A 55-year-old man with diabetes and a complicated urinary tract infection
He had a urinary tract infection with both bacteria and yeast. He was started on this medicine after culture reports. His doctor monitored his kidney function and blood sugar closely. He was advised to drink plenty of water. He completed a 10-day course and recovered well.
💡 Lesson: In patients with diabetes, monitoring blood sugar and kidney function is important while taking this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2 to 3 days, but it may take longer depending on the infection. Complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food is recommended to reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I drink alcohol while taking this medicine?

A: No, you should avoid alcohol as it can increase the risk of liver problems and worsen side effects.

Q: Is this medicine safe during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. Fluconazole may be harmful to the fetus, especially at high doses.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with antacids?

🛑 Myths vs. Facts

  • Myth: This medicine can cure any infection.
    Fact: This medicine only treats specific bacterial and fungal infections. It does not work for viral infections like colds or flu.
  • Myth: I can stop taking it once I feel better.
    Fact: You must complete the full course to prevent the infection from returning and to avoid resistance.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol should be avoided as it can increase the risk of liver problems and worsen side effects.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with certain allergies, liver disease, kidney disease, or during pregnancy without medical advice.

🔄 Alternative Options

Generic Alternatives

  • Fluconazole 150 mg + Cefixime 200 mg tablet

Brand Alternatives

  • Alcan 150mg/200mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Fluconazole 150 mg + Cefixime 200 mg","use":"Mixed bacterial and fungal infections","route":"Oral"},{"medicine":"Fluconazole 150 mg tablet","composition":"Fluconazole 150 mg","use":"Fungal infections only","route":"Oral"},{"medicine":"Cefixime 200 mg tablet","composition":"Cefixime 200 mg","use":"Bacterial infections only","route":"Oral"}]

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