Duokind E 30mg/20mg Capsule: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Muscle stiffness, tremors, or involuntary movements
- Swelling of face, lips, or throat
- Difficulty breathing
- Severe abdominal pain or blood in vomit/stool
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is raciper d 20 capsule sr used for?
This medicine is a combination of Domperidone and Esomeprazole used to treat acid reflux and related symptoms. It works by reducing stomach acid and improving stomach emptying. It is usually taken once daily before a meal.
- Generic Name: Domperidone (30mg) + Esomeprazole (20mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 raciper d 20 capsule sr के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और एसोमेप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, हार्टबर्न, और अपच के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट खाली होने की गति को बढ़ाती है। यह आमतौर पर भोजन से पहले एक बार ली जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, दस्त, मतली, पेट दर्द, और मुंह सूखना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, स्तन में दर्द या सूजन, और मांसपेशियों में अकड़न हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन से 30-60 मिनट पहले खाली पेट लें। इसे चबाएं नहीं, पूरा निगल लें। शराब का सेवन न करें। अगर आपको चक्कर आते हैं तो वाहन न चलाएं। दवा को बच्चों से दूर रखें।
💊 raciper d 20 capsule sr Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine helps relieve heartburn, acid regurgitation, and difficulty swallowing by reducing stomach acid and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It is used to treat symptoms of functional dyspepsia such as postprandial fullness, early satiety, and epigastric pain.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"Domperidone component helps improve gastric emptying in patients with diabetic or idiopathic gastroparesis.","evidence":"Moderate"},{"condition":"Nausea and vomiting","description":"The domperidone component provides antiemetic effects, useful in various gastrointestinal disorders.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of NSAID-induced ulcers","description":"Esomeprazole component may be used off-label to prevent ulcers in patients on chronic NSAID therapy.","evidence":"Limited"},{"condition":"Zollinger-Ellison syndrome","description":"High-dose esomeprazole is sometimes used off-label to manage hypersecretory conditions.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastroparesis, Nausea and vomiting
📋 Drug Information
| Generic Name(s) | Domperidone (30mg) + Esomeprazole (20mg) |
| Brand Name | raciper d 20 capsule sr |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Domperidone is a peripherally acting dopamine D2 receptor antagonist that enhances gastrointestinal motility and accelerates gastric emptying without crossing the blood-brain barrier significantly. Esomeprazole is a proton pump inhibitor that irreversibly inhibits the H+/K+-ATPase enzyme in gastric parietal cells, thereby reducing basal and stimulated gastric acid secretion. The combination provides both symptomatic relief by improving motility and reducing acid exposure to the esophagus.
Mechanism Steps
💡 How to Take raciper d 20 capsule sr
Strength: Capsule containing Domperidone 30mg and Esomeprazole 20mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily, preferably on an empty stomach, at least 30-60 minutes before breakfast. However, the dose and frequency may vary depending on the indication, severity of symptoms, and patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially cardiac and extrapyramidal side effects. Use with caution and consider lower initial doses. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Dose adjustment may be necessary in patients with severe renal impairment (creatinine clearance <30 mL/min). Consult a doctor for appropriate dosing. |
| Hepatic Impairment | Contraindicated in patients with moderate to severe hepatic impairment. In mild hepatic impairment, use with caution and consider dose reduction. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Domperidone 30mg + Esomeprazole 20mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of raciper d 20 capsule sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Warfarin | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Major | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Atazanavir | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Warfarin
- Methotrexate
⚡ Moderate Interactions
- Clopidogrel
- Diazepam
- Phenytoin
- Atazanavir, nelfinavir
🍷 Alcohol Interaction
Alcohol may exacerbate gastrointestinal side effects such as nausea, abdominal pain, and diarrhea. It can also increase the risk of liver toxicity and may worsen the underlying condition being treated. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone, esomeprazole, or any component of the formulation","Gastrointestinal obstruction, perforation, or bleeding","Moderate to severe hepatic impairment","Known QT prolongation or family history of long QT syndrome","Concomitant use with QT-prolonging drugs or strong CYP3A4 inhibitors","Prolactin-releasing pituitary tumor (prolactinoma)","Breast cancer","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of cardiac arrhythmias and extrapyramidal symptoms.","Avoid use in patients with underlying heart disease or electrolyte imbalances.","Long-term use of esomeprazole may increase risk of bone fractures, hypomagnesemia, and vitamin B12 deficiency.","May mask symptoms of gastric malignancy; rule out malignancy before starting therapy.","Use with caution in patients with renal impairment; dose adjustment may be needed.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use for longer than prescribed without medical supervision.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Domperidone is excreted in breast milk and may cause adverse effects in the infant. Esomeprazole is also excreted in breast milk. This medicine is not recommended during breastfeeding unless the benefit outweighs the risk. Consult your doctor.
💊 Overdose Management
Overdose may cause severe extrapyramidal symptoms, cardiac arrhythmias, and gastrointestinal effects. There is no specific antidote. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion is recent. Monitor cardiac rhythm and vital signs. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a glass of water. It is best taken on an empty stomach, at least 30-60 minutes before a meal, to maximize absorption. Avoid alcohol while taking this medicine as it may worsen side effects and reduce effectiveness. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. Inform your doctor if you have a history of heart problems, liver disease, or kidney disease. Do not use this medicine for longer than recommended without medical supervision. Keep out of reach of children. Store at room temperature away from moisture and heat. If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of cardiac arrhythmias, extrapyramidal symptoms, and drug interactions. Use with caution and consider lower doses. Regular monitoring of renal and hepatic function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Both domperidone and esomeprazole should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your surgeon. It may affect gastric motility and acid secretion, which could impact post-operative recovery. Inform your surgeon about all medicines you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may recommend temporary discontinuation or alternative management.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid vigorous activities immediately after taking the medicine, especially if you experience dizziness. Listen to your body and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor may adjust the dose or switch to an alternative therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of bone fractures, hypomagnesemia, vitamin B12 deficiency, and gastrointestinal infections. Domperidone long-term use may cause tardive dyskinesia and cardiac arrhythmias. Regular monitoring of magnesium, vitamin B12, and renal function is advised. Periodic review of the need for continued therapy is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can significantly reduce reflux symptoms.
Evidence: Well-establishedFor severe GERD not responding to medication, surgical options may be considered.
Evidence: Well-establishedSome herbs like ginger and licorice may help, but evidence is limited and they can interact with medicines.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, long-term use of esomeprazole may increase the risk of certain infections; ensure routine vaccinations are up to date.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust the dosing schedule gradually in consultation with your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Domperidone starts working within 30-60 minutes, while esomeprazole may take 1-4 days for full acid suppression effect.
A: It can interact with several drugs, including blood thinners, antifungals, and certain antidepressants. Always inform your doctor about all medicines you are taking.
A: Use during pregnancy only if clearly needed and prescribed by a doctor. Both ingredients should be used with caution.
A: Common side effects include headache, diarrhea, nausea, abdominal pain, and dry mouth. These are usually mild and transient.
A: Do not stop without consulting your doctor. Abrupt discontinuation may cause rebound acid hypersecretion.
🤔 Common Patient Concerns
🔄 Substitutes for raciper d 20 capsule sr
View AllAlternative brands with exact same active ingredient:
-
ignis 30 mg/20 mg capsuleAlembic Pharmaceuticals Ltd ₹44.36 30.7% CHEAPER
-
esaktive d 30mg/20mg capsuleSava Medica Limited ₹50.63 20.9% CHEAPER
-
esotaj-d 30mg/20mg tabletTaj Pharma India Ltd ₹58.35 8.8% CHEAPER
-
esolead 30mg/20mg capsuleHealth Guard India Pvt Ltd ₹83.90 31.1% COSTLIER
-
esoprol-dsr capsuleJohnlee Pharmaceuticals Pvt Ltd ₹84.38 31.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken indefinitely for acid reflux.
Fact: Long-term use should be under medical supervision due to potential risks like bone fractures and vitamin deficiencies. - Myth: It is safe to take with any other medication.
Fact: It can interact with several drugs, including blood thinners and certain antifungals, so always inform your doctor. - Myth: You can stop taking it as soon as you feel better.
Fact: Complete the prescribed course and consult your doctor before stopping to prevent relapse.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Esomeprazole generic capsules
Brand Alternatives
- Duokind E 30mg/20mg Capsule