Regestrone CR 10mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden shortness of breath or chest pain
- Swelling, redness, or pain in one leg
- Severe abdominal pain or tenderness
- Yellowing of the skin or eyes (jaundice)
- Severe headache with visual disturbances
- Unusual vaginal bleeding that is heavy or persistent
- Signs of allergic reaction: rash, itching, swelling of face or throat
If experiencing severe symptoms, call emergency services immediately.
What is progeston 10mg tablet used for?
This medicine is a progestin used to treat abnormal uterine bleeding, endometriosis, and menstrual irregularities. It works by mimicking progesterone to regulate the uterine lining.
- Generic Name: Norethisterone (10mg)
- Manufacturer: Mac Millon Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 progeston 10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नोरेथिस्टेरोन 10 मिलीग्राम युक्त एक प्रोजेस्टिन है, जिसका उपयोग असामान्य गर्भाशय रक्तस्राव, एंडोमेट्रियोसिस और मासिक धर्म की अनियमितताओं के इलाज के लिए किया जाता है। यह प्राकृतिक प्रोजेस्टेरोन की तरह काम करके गर्भाशय की परत को नियंत्रित करती है। यह दवा गर्भनिरोधक नहीं है और इसे डॉक्टर की सलाह के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, स्तन में कोमलता और मासिक धर्म में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन रक्त के थक्के, यकृत की समस्या और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको सीने में दर्द, सांस लेने में कठिनाई, या पैरों में सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर यदि आपको रक्त के थक्के, यकृत रोग, या कैंसर का इतिहास है। गर्भवती होने पर यह दवा न लें। इस दवा को लेते समय धूम्रपान और शराब से बचें। दवा को डॉक्टर के बताए अनुसार ही लें, अपने आप मात्रा न बढ़ाएं या घटाएं।
💊 progeston 10mg tablet Uses & Benefits
[{"condition":"Abnormal uterine bleeding","description":"This medicine helps control heavy or irregular bleeding by stabilizing the uterine lining.","evidence":"Well-established"},{"condition":"Endometriosis","description":"It reduces pain and lesions associated with endometriosis by suppressing endometrial growth.","evidence":"Well-established"},{"condition":"Menstrual cycle regulation","description":"Used to regulate irregular periods and treat conditions like oligomenorrhea.","evidence":"Well-established"},{"condition":"Delay of menstruation","description":"Sometimes prescribed to postpone menstruation for a short period for convenience or medical reasons.","evidence":"Well-established"},{"condition":"Hormone replacement therapy","description":"Used in combination with estrogen for women with an intact uterus to prevent endometrial hyperplasia.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Premenstrual syndrome (PMS)","description":"May be used off-label to alleviate severe PMS symptoms, though evidence is limited.","evidence":"Limited"},{"condition":"Catamenial epilepsy","description":"Occasionally used to reduce seizure frequency related to menstrual cycles.","evidence":"Limited"}]
Primary treatment for: Abnormal uterine bleeding
Also treats: Endometriosis, Menstrual irregularities, Hormone replacement therapy
📋 Drug Information
| Generic Name(s) | Norethisterone (10mg) |
| Brand Name | progeston 10mg tablet |
| Manufacturer | Mac Millon Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Progestins (First generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to progesterone receptors in target tissues such as the endometrium, myometrium, and hypothalamus. By mimicking the action of natural progesterone, it transforms the proliferative endometrium into a secretory state, which helps regulate bleeding and reduce endometrial thickness. It also suppresses gonadotropin release, leading to reduced ovarian stimulation and decreased estrogen production. This results in a variety of therapeutic effects, including control of abnormal uterine bleeding and reduction of endometriotic lesions.
Mechanism Steps
💡 How to Take progeston 10mg tablet
Strength: Norethisterone 10mg immediate-release tablet
Dosage Information
| Adult Dosage | The dosage of this medicine varies depending on the condition being treated. For abnormal uterine bleeding, a common regimen is 5 mg three times daily for 10 days. For endometriosis, doses may range from 10 to 15 mg daily. For delay of menstruation, 5 mg three times daily may be started 3 days before the expected period. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and monitor for side effects. |
| Renal Impairment | No specific dose adjustment provided. Use with caution in patients with renal impairment. |
| Hepatic Impairment | Contraindicated in severe hepatic impairment. Use with caution in mild to moderate impairment. |
| Maximum Daily Dose | The maximum daily dose varies by indication; up to 30 mg per day has been used in some conditions. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of progeston 10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Rifampicin | Major | |
| Carbamazepine | Major | |
| Phenytoin | Moderate | |
| St. John's wort | Moderate |
🚨 Major Interactions
- Warfarin
- Rifampicin
- Carbamazepine
⚡ Moderate Interactions
- Phenytoin
- St. John's wort
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and liver strain. It is advisable to limit or avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known or suspected pregnancy","History of blood clots (thrombophlebitis, pulmonary embolism)","Active or history of liver disease","Known or suspected breast cancer","Undiagnosed vaginal bleeding","Hypersensitivity to norethisterone"]
⚠️ Warnings & Precautions
["Use with caution in patients with a history of depression.","May cause fluid retention; monitor in patients with heart or kidney disease.","May affect glucose tolerance; monitor blood sugar in diabetics.","Avoid in patients with a history of migraine with aura.","Do not use as a contraceptive."]
🤱 Lactation Safety
Norethisterone is excreted in breast milk. Small amounts may affect the infant. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, and withdrawal bleeding. There is no specific antidote. Treatment is symptomatic and supportive. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor about all your medical conditions, especially if you have a history of blood clots, liver disease, migraines, or cancer. Do not take this medicine if you are pregnant or planning to become pregnant, as it may harm the fetus. Use effective non-hormonal contraception while on this medicine. Avoid smoking while taking this medicine, as it increases the risk of blood clots. Limit alcohol consumption, as it may worsen side effects like dizziness. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Take this medicine exactly as prescribed; do not increase or decrease the dose without consulting your doctor. If you miss a dose, follow your doctor's instructions. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially regarding cardiovascular risks. Use with caution and monitor regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are trying to conceive. It may interfere with ovulation and is contraindicated during pregnancy. Consult your doctor for alternative treatments if you are planning pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine, as it may increase the risk of blood clots during and after surgery. Your doctor may advise you to stop it temporarily.
🦷 Dental Procedures
No specific precautions for dental procedures, but inform your dentist about all medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise if you feel unwell. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause mood changes that could affect your work; discuss with your doctor if this becomes an issue.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation may cause withdrawal bleeding or worsening of symptoms. Your doctor will advise you on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of blood clots, liver problems, and bone density loss. Regular monitoring of liver function and blood pressure is recommended. Discuss with your doctor about the need for continued use and potential alternatives.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For heavy bleeding, options include tranexamic acid or NSAIDs.
Evidence: Well-establishedWeight management, exercise, and stress reduction can help hormonal balance.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check local customs regulations regarding prescription medications before travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For control of uterine bleeding, effects may be seen within 24 to 48 hours. For other conditions, it may take several days to weeks.
A: No, this medicine is contraindicated during pregnancy as it may harm the fetus. Consult your doctor immediately if you become pregnant.
A: This medicine passes into breast milk. Consult your doctor before breastfeeding.
🤔 Common Patient Concerns
🔄 Substitutes for progeston 10mg tablet
View AllAlternative brands with exact same active ingredient:
-
secam p 10mg tabletMcW Healthcare ₹34.69 20.2% CHEAPER
-
promid tabletMidas Healthcare Ltd ₹39.90 8.2% CHEAPER
-
progestil tabletMacwin Pharma ₹40.00 7.9% CHEAPER
-
noster 10mg tabletTNT Lifesciences ₹73.13 68.3% COSTLIER
-
gynatron 10mg tabletTridev Pharmaceutical ₹89.06 105% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a contraceptive.
Fact: This medicine is not a contraceptive and should not be used for birth control. - Myth: It can be taken without a prescription.
Fact: This medicine is a prescription drug and must be used under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Norethisterone 10mg tablet
Brand Alternatives
- Regestrone CR 10mg tablet