Algirest M Syrup: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or worsening asthma symptoms
- Severe dizziness or fainting
- Fast, irregular, or pounding heartbeat
- New or worsening mood changes, agitation, aggression, depression, or suicidal thoughts
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Severe skin rash or blistering
If experiencing severe symptoms, call emergency services immediately.
What is algirest m syrup used for?
This medicine is a prescription oral syrup containing montelukast and fexofenadine. It is used to treat allergic rhinitis, chronic urticaria, and selected cases of mild persistent asthma. It works by blocking leukotriene and histamine pathways. It is not a rescue medicine for acute asthma attacks.
- Generic Name: Montelukast (4mg/5ml) + Fexofenadine (60mg/5ml)
- Manufacturer: Mac Millon Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 algirest m syrup के बारे में (Hindi Summary)
उपयोग: यह दवा मोंटेलुकास्ट और फेक्सोफेनाडीन का संयोजन है, जिसका उपयोग एलर्जी राइनाइटिस, पुरानी पित्ती और हल्के लगातार दमा के इलाज के लिए किया जाता है। यह छींक, नाक बहना, खुजली, आंखों में पानी आना और त्वचा की खुजली को कम करने में मदद करती है। यह दवा सूजन और एलर्जी पैदा करने वाले रसायनों को रोककर काम करती है। यह दमा के तीव्र दौरे के लिए राहत दवा नहीं है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, हल्की नींद आना, मुंह सूखना, जी मिचलाना और थकान शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई, तेज धड़कन, और मूड या व्यवहार में बदलाव जैसे चिड़चिड़ापन, अवसाद या आत्मघाती विचार शामिल हो सकते हैं। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें और बिना सलाह बंद न करें। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं और दी गई मापने वाली कप या सिरिंज से ही खुराक नापें। इसे फलों के रस के साथ न लें, क्योंकि इससे दवा का असर कम हो सकता है। एल्युमिनियम या मैग्नीशियम वाले एंटासिड के साथ इस दवा को न लें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। इस दवा को कमरे के तापमान पर, धूप से दूर और बच्चों की पहुंच से बाहर रखें।
💊 algirest m syrup Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, nasal itching, and itchy watery eyes caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Chronic urticaria","description":"Reduces itching, redness, and wheals in chronic spontaneous urticaria when antihistamine therapy alone is insufficient.","evidence":"Moderate"},{"condition":"Mild persistent asthma","description":"Used as add-on controller therapy in selected patients with mild persistent asthma and allergic triggers.","evidence":"Moderate"},{"condition":"Exercise-induced bronchoconstriction","description":"May reduce airway narrowing triggered by exercise in patients with known exercise-induced symptoms.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Atopic dermatitis","description":"Sometimes used to reduce itching in atopic dermatitis, though it is not a primary treatment.","evidence":"Limited"},{"condition":"Sleep disturbance due to allergic rhinitis","description":"May improve sleep quality by controlling nighttime allergic symptoms.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Chronic urticaria, Mild persistent asthma, Exercise-induced bronchoconstriction
📋 Drug Information
| Generic Name(s) | Montelukast (4mg/5ml) + Fexofenadine (60mg/5ml) |
| Brand Name | algirest m syrup |
| Manufacturer | Mac Millon Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed and out of reach of children. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Montelukast selectively blocks cysteinyl leukotriene receptors, preventing leukotriene-mediated airway inflammation, bronchoconstriction, mucus secretion, and oedema. Fexofenadine selectively blocks peripheral H1 histamine receptors, reducing histamine-driven sneezing, itching, rhinorrhoea, and urticaria. The combination targets both leukotriene and histamine pathways, which can provide broader symptom control in allergic conditions than either agent alone.
Mechanism Steps
💡 How to Take algirest m syrup
Strength: Each 5 ml of syrup contains montelukast 4 mg and fexofenadine 60 mg.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, kidney function, and liver function. In adults, the usual prescribed dose is taken once daily, preferably in the evening for asthma or as directed for allergic conditions. Do not self-adjust the dose. Follow your doctor's instructions exactly and use the measuring cup or oral syringe provided to measure each dose accurately. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Dose adjustment may be needed based on kidney and liver function. Consult your doctor for appropriate dosing. |
| Renal Impairment | Fexofenadine dose adjustment may be needed in patients with severe kidney impairment. Montelukast does not require dose adjustment in kidney disease. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Montelukast dose adjustment may be needed in patients with severe liver impairment. Fexofenadine does not require dose adjustment in liver disease. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose must be determined by a qualified clinician based on the patient's age, weight, and clinical condition. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of algirest m syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aluminium or magnesium-containing antacids | Major | |
| Gemfibrozil | Major | |
| Rifampicin | Major | |
| Erythromycin | Moderate | |
| Ketoconazole | Moderate | |
| Phenobarbital | Moderate | |
| Alcohol | Moderate | |
| Paracetamol | Minor | |
| Ibuprofen | Minor | |
| Fruit juices | Moderate |
🚨 Major Interactions
- Aluminium or magnesium-containing antacids
- CYP2C8 inhibitors such as gemfibrozil
- CYP3A4 inducers such as rifampicin
⚡ Moderate Interactions
- Erythromycin
- Ketoconazole
- Phenobarbital
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid or limit alcohol while taking this medicine, especially if you need to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to montelukast or fexofenadine","Acute asthma attack or status asthmaticus","Severe liver impairment without medical supervision","Severe kidney impairment without medical supervision","Children below the age recommended by the prescribing doctor"]
⚠️ Warnings & Precautions
["This medicine is not a rescue medicine for acute asthma attacks. Always keep a rescue inhaler available if prescribed.","Neuropsychiatric events such as agitation, aggression, depression, and suicidal thoughts have been reported with montelukast. Report any mood or behaviour changes to your doctor immediately.","Do not take this medicine with fruit juices or antacids containing aluminium or magnesium, as these can reduce its effectiveness.","Avoid driving or operating machinery until you know how this medicine affects you, as it may cause drowsiness.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not stop this medicine suddenly without consulting your doctor, especially if it is being used for asthma control.","Keep this medicine out of reach of children and store it as directed."]
🤱 Lactation Safety
Montelukast and fexofenadine may pass into breast milk in small amounts. Fexofenadine is generally considered compatible with breastfeeding, but montelukast data are limited. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause drowsiness, dizziness, headache, nausea, or palpitations. If you suspect an overdose, contact your doctor or visit the nearest emergency department immediately. Do not try to induce vomiting unless instructed by a healthcare professional. Treatment is supportive and based on symptoms.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase, decrease, or stop the dose on your own. Shake the bottle well before each use and measure the dose with the measuring cup or oral syringe provided. This medicine is not a rescue inhaler and must not be used to treat a sudden asthma attack or breathing emergency. Avoid taking it at the same time as antacids that contain aluminium or magnesium, because these can reduce the absorption of fexofenadine. Keep all follow-up appointments so your doctor can monitor your response and check for side effects. Tell your doctor about all other medicines, supplements, and herbal products you take. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before using this medicine. Store it at room temperature, away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Kidney and liver function should be assessed before starting this medicine, and dose adjustment may be needed. Regular monitoring for side effects is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Montelukast and fexofenadine are generally considered acceptable during pregnancy when the benefit outweighs the risk, but data are limited. Your doctor will decide whether to continue or change your treatment based on your condition.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. There are no specific restrictions, but your doctor may advise you to continue or temporarily stop it based on your overall health and the type of surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific restrictions, but if you experience drowsiness, avoid driving to and from the appointment. Maintain good oral hygiene to prevent dental problems.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine. However, if you have exercise-induced bronchoconstriction, consult your doctor about using a rescue inhaler before exercise. Avoid strenuous outdoor exercise during high pollen counts if you have allergic asthma. Stay hydrated and warm up properly before exercising.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but if you experience significant drowsiness, consult your doctor. The medicine should not affect your ability to work or study once you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as severe allergic reactions, mood changes, or palpitations, seek medical advice immediately. Your doctor will decide whether to stop the medicine or adjust the dose based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated when prescribed and monitored by a doctor. Montelukast has been associated with rare neuropsychiatric events, and periodic review of mood and behaviour is advised, especially in children. Liver function may need monitoring in patients with existing liver disease. Fexofenadine is considered safe for long-term use, but kidney function should be monitored in patients with kidney impairment. Regular follow-up with your doctor is recommended to assess the continued need for therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to known allergens can help control allergic symptoms.
Evidence: Well-establishedRinsing the nasal passages with saline can help relieve nasal congestion and irritation.
Evidence: ModerateAllergy shots or sublingual immunotherapy can reduce sensitivity to allergens over time.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interfere with the effectiveness of vaccines. However, if you are scheduled for allergy testing, inform your doctor, as antihistamines like fexofenadine may interfere with skin test results. Your doctor may advise you to stop this medicine temporarily before allergy testing.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription and a doctor's note if you are travelling internationally. Store it at room temperature and protect it from direct sunlight and moisture during travel. If you are crossing time zones, consult your doctor about how to adjust the timing of your dose. Keep it in your hand luggage rather than checked baggage to avoid loss or temperature extremes. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Fexofenadine starts relieving allergic symptoms within about one hour, while montelukast may take several days to show its full effect. Follow your doctor's advice for the best results.
A: Yes, this medicine can be taken with or without food. However, avoid taking it with fruit juices such as grapefruit, orange, or apple juice, as these can reduce its absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine should be used in children only under the supervision of a pediatrician. The dose is individualized based on the child's age, weight, and condition.
A: Do not stop this medicine without consulting your doctor, especially if it is being used for asthma control. Stopping suddenly may cause symptoms to return.
🤔 Common Patient Concerns
🔄 Substitutes for algirest m syrup
View AllAlternative brands with exact same active ingredient:
-
stayhappi montelukast+fexofenadine 4mg/60mg syrupSarvagunaushdhi Pvt Ltd ₹65.63 35.2% CHEAPER
-
delpodine m suspensionDelcure Life Sciences ₹88.13 13% CHEAPER
-
minolast fx oral suspensionLeeford Healthcare Ltd ₹93.75 7.4% CHEAPER
-
hhfexo m oral suspensionHegde and Hegde Pharmaceutical LLP ₹103.13 1.9% COSTLIER
-
montem fx syrupNemi Pharmaceuticles ₹103.13 1.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to treat a sudden asthma attack.
Fact: This medicine is not a rescue medicine. Acute asthma attacks require a fast-acting rescue inhaler and immediate medical attention. - Myth: This medicine causes drowsiness in everyone.
Fact: Fexofenadine is a non-drowsy antihistamine, but some people may still experience mild drowsiness. Avoid driving until you know how it affects you. - Myth: This medicine can be taken with fruit juice.
Fact: Fruit juices such as grapefruit, orange, and apple juice can reduce the absorption of fexofenadine. Take this medicine with water instead. - Myth: This medicine can be stopped as soon as symptoms improve.
Fact: Do not stop this medicine without consulting your doctor, especially if it is being used for asthma control.
🔄 Alternative Options
Generic Alternatives
- Montelukast and fexofenadine combination generic syrup
Brand Alternatives
- Algirest M Syrup