Hemolit Cream: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of face, lips, or throat.
- Difficulty breathing or wheezing.
- Irregular heartbeat or palpitations.
- Severe dizziness or fainting.
- Signs of systemic toxicity such as confusion, tremors, or seizures.
- Severe skin rash, blistering, or peeling.
- No improvement or worsening of symptoms after 7 days of use.
If experiencing severe symptoms, call emergency services immediately.
What is pilo-smooth cream used for?
This medicine is a topical cream containing lidocaine 3% w/w and calcium dobesilate 0.25% w/w. It is used to relieve pain, swelling, and heaviness associated with superficial venous disorders and localized inflammation. Apply a thin layer to the affected area 2-3 times daily or as directed by a doctor.
- Generic Name: Lidocaine (3% w/w) + Calcium Dobesilate (0.25% w/w)
- Manufacturer: Prevego Healthcare & Research Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pilo-smooth cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें लिडोकेन 3% w/w और कैल्शियम डोबेसिलेट 0.25% w/w शामिल हैं। इसका उपयोग नसों की समस्या से होने वाले दर्द, सूजन और भारीपन को कम करने के लिए किया जाता है। यह मामूली चोट, कीड़े के काटने और त्वचा की सूजन में भी राहत देती है। यह दवा प्रभावित क्षेत्र पर पतली परत में लगाई जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर लालिमा, खुजली, जलन या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी एलर्जी की प्रतिक्रिया हो सकती है जैसे दाने या सूजन। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, चक्कर आना या दिल की धड़कन अनियमित हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को केवल त्वचा पर लगाएं। आंखों, मुंह और खुले घावों के संपर्क में न आने दें। लगाने से पहले और बाद में हाथ धोएं। डॉक्टर की सलाह के बिना इसे अधिक मात्रा में या लंबे समय तक न लगाएं। अगर लक्षण 7 दिनों में ठीक न हों तो डॉक्टर से परामर्श करें। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 pilo-smooth cream Uses & Benefits
[{"condition":"Superficial venous insufficiency","description":"Relieves pain, heaviness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in the legs associated with poor venous circulation.","evidence":"Moderate"},{"condition":"Localized pain and inflammation","description":"Provides temporary relief from pain and swelling due to minor injuries, sprains, or insect bites.","evidence":"Moderate"},{"condition":"Hemorrhoids","description":"May be used to reduce pain and swelling of external hemorrhoids, though evidence is limited.","evidence":"Limited"},{"condition":"Diabetic microangiopathy","description":"Calcium dobesilate component may help improve microcirculation, but topical use for this indication is not well established.","evidence":"Limited"}]
Off-label uses: [{"condition":"Post-surgical bruising","description":"Sometimes applied to reduce bruising and swelling after minor surgical procedures.","evidence":"Limited"},{"condition":"Chronic venous ulcers","description":"May be used as an adjunct to standard wound care, but should not be applied directly to open ulcers without medical supervision.","evidence":"Limited"}]
Primary treatment for: Superficial venous insufficiency
Also treats: Localized pain and inflammation, Hemorrhoids, Diabetic microangiopathy
📋 Drug Information
| Generic Name(s) | Lidocaine (3% w/w) + Calcium Dobesilate (0.25% w/w) |
| Brand Name | pilo-smooth cream |
| Manufacturer | Prevego Healthcare & Research Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Protect from direct sunlight and moisture. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a local anesthetic and a venoactive agent. Lidocaine works by blocking voltage-gated sodium channels in nerve cell membranes, which prevents the generation and conduction of nerve impulses, thereby producing local numbness and pain relief. Calcium dobesilate is a synthetic venoactive compound that reduces capillary permeability, inhibits platelet aggregation, and improves erythrocyte flexibility, leading to better microcirculation and reduced edema. Together, they provide symptomatic relief from pain and swelling when applied topically.
Mechanism Steps
💡 How to Take pilo-smooth cream
Strength: Cream containing lidocaine 3% w/w and calcium dobesilate 0.25% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area 2 to 3 times daily, or as directed by your doctor. Gently massage until absorbed. The dose and frequency may vary depending on the condition being treated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of lidocaine. Use with caution and follow the doctor's instructions. No specific dose adjustment is established for topical use, but individualization is recommended. |
| Renal Impairment | No specific dose adjustment is established for topical use. However, in patients with severe renal impairment, systemic absorption of lidocaine metabolites may be prolonged. Use with caution and consult a doctor. |
| Hepatic Impairment | No specific dose adjustment is established for topical use. In patients with severe hepatic impairment, lidocaine clearance may be reduced. Use with caution and consult a doctor. |
| Maximum Daily Dose | The maximum daily dose for topical application is not established from the available information. Do not exceed the frequency recommended by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pilo-smooth cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Class I antiarrhythmics | Major | |
| Cimetidine | Major | |
| Beta-blockers | Moderate | |
| Other local anesthetics | Moderate | |
| Topical corticosteroids | Minor |
🚨 Major Interactions
- Class I antiarrhythmics (e.g., tocainide, mexiletine)
- Cimetidine
⚡ Moderate Interactions
- Beta-blockers (e.g., propranolol)
- Other local anesthetics
🍷 Alcohol Interaction
No specific interaction between alcohol and topically applied lidocaine or calcium dobesilate has been established. However, alcohol consumption may worsen underlying conditions such as venous insufficiency. It is advisable to limit alcohol intake while using this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to lidocaine, calcium dobesilate, or any component of the cream.","Application to large areas of broken or infected skin.","Use in children under 12 years without medical advice.","Ophthalmic, oral, or internal use."]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes and mucous membranes.","Do not apply to open wounds or areas of infection.","Do not use with occlusive dressings unless directed by a doctor.","Avoid prolonged use over large areas without medical supervision.","Consult a doctor if symptoms persist or worsen after 7 days of use.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid concurrent use of other topical products on the same area without medical advice."]
🤱 Lactation Safety
It is not known whether lidocaine or calcium dobesilate passes into breast milk after topical application. To minimize infant exposure, avoid applying the cream to the breast area. Consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose from topical application is unlikely if used as directed. If excessive amounts are applied or ingested, seek immediate medical attention. Symptoms of lidocaine toxicity include dizziness, confusion, seizures, and cardiac arrhythmias. Treatment is supportive and symptomatic. In case of accidental ingestion, contact a poison control center or emergency services immediately.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine only to intact skin and avoid contact with eyes, mucous membranes, and open wounds. Wash your hands thoroughly before and after application unless the hands are the treated area. Do not cover the treated area with airtight dressings unless instructed by a doctor, as this can increase absorption. Avoid using heating pads or warm compresses over the cream. Do not exceed the recommended frequency or duration of use. If your symptoms worsen or do not improve after a few days, consult a healthcare professional. Keep this medicine away from children and pets. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you have a history of allergic reactions to lidocaine or calcium dobesilate. Avoid concurrent use of other topical products on the same area without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of lidocaine. Use with caution and follow your doctor's instructions. Monitor for any signs of skin irritation or systemic effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical lidocaine is generally considered safe in small amounts, but calcium dobesilate should be used with caution. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
After surgery, do not apply this medicine to surgical wounds unless specifically instructed by your surgeon. It may be used on intact skin around the surgical area for pain relief, but always follow your surgeon's advice.
🦷 Dental Procedures
This medicine is for topical skin use and is not intended for oral or dental procedures. For dental pain, consult a dentist for appropriate treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while using this medicine. However, if you have venous insufficiency, avoid high-impact activities that may worsen symptoms. Listen to your body and consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to work or drive. However, if you experience dizziness or drowsiness (rare), avoid driving or operating heavy machinery until you feel alert.
🛑 When to Stop This Medicine
Stop using this medicine and consult a doctor if your symptoms do not improve after 7 days, if they worsen, or if you experience any severe side effects such as allergic reactions or signs of systemic toxicity. Do not stop prescribed treatment without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged application over large areas may increase the risk of systemic absorption of lidocaine, leading to potential toxicity. Calcium dobesilate is generally well tolerated, but long-term safety data for topical use are limited. Regular follow-up with your doctor is recommended to assess continued need and monitor for any adverse effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Wearing compression stockings can help reduce swelling and improve venous return.
Evidence: Well-establishedElevating legs above heart level several times a day reduces swelling.
Evidence: Well-establishedMedications like diosmin and hesperidin can be taken orally for venous insufficiency.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions between this medicine and vaccines. Continue with routine vaccinations as per schedule.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and heat. If you are traveling across time zones, continue applying as per your usual schedule; no time adjustment is needed for topical use.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The numbing effect starts within 5-10 minutes, while the anti-swelling effect may take a few days of regular use.
A: No, it should not be applied to open wounds or infected skin. Consult a doctor for proper wound care.
A: It is not recommended for children under 12 without medical advice. Consult a pediatrician.
A: Apply it as soon as you remember, but if it's almost time for the next dose, skip the missed dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for pilo-smooth cream
View AllAlternative brands with exact same active ingredient:
-
retiver creamFloreat Medica Pvt Ltd ₹65.53 43.8% CHEAPER
-
anasure creamLifeline Remedies India Pvt Ltd ₹84.28 27.8% CHEAPER
-
pilowis creamDelwis Healthcare Pvt Ltd ₹85.00 27.2% CHEAPER
-
logisil-h creamCanixa Life Sciences Pvt ₹106.88 8.4% CHEAPER
-
well pi creamWellcuring Lifesciences Pvt Ltd ₹118.00 1.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used on any skin problem.
Fact: It is specifically for pain and swelling related to venous issues and minor injuries. It should not be used on open wounds or infections. - Myth: More cream means faster relief.
Fact: Applying more than the recommended amount does not speed up relief and may increase the risk of side effects. - Myth: It is safe to use indefinitely.
Fact: Prolonged use without medical supervision is not recommended. Consult a doctor if symptoms persist beyond 7 days.
🔄 Alternative Options
Generic Alternatives
- Lidocaine 3% w/w + Calcium Dobesilate 0.25% w/w cream (various manufacturers)
Brand Alternatives
- Hemolit Cream