Atorlip-ASP 20 Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual muscle pain, tenderness, or weakness
- Dark brown or cola-colored urine
- Persistent nausea or vomiting
If experiencing severe symptoms, call emergency services immediately.
What is atorvatin ap 20/75 capsule used for?
This medicine is a combination of Atorvastatin 20 mg and Aspirin 75 mg used to lower cholesterol and prevent blood clots in patients at high risk of heart attack or stroke. It is taken orally once daily, usually in the evening, and requires regular monitoring of liver function and bleeding signs.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Prevego Healthcare & Research Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 atorvatin ap 20/75 capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरवास्टेटिन 20 मिलीग्राम और एस्पिरिन 75 मिलीग्राम का संयोजन है। इसका उपयोग कोलेस्ट्रॉल कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है, जिससे दिल के दौरे और स्ट्रोक का खतरा कम होता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें हृदय रोग, मधुमेह या उच्च कोलेस्ट्रॉल की समस्या है। यह दवा रक्त में एलडीएल कोलेस्ट्रॉल को कम करती है और प्लेटलेट्स को चिपकने से रोकती है। इसे डॉक्टर की सलाह के अनुसार ही लें, स्वयं न लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में अपच, पेट में जलन, मतली, सिरदर्द, मांसपेशियों में दर्द और आसानी से चोट लगने पर खून बहना शामिल है। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, एलर्जी और मांसपेशियों का टूटना (रैब्डोमायोलिसिस) शामिल हैं। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, या मांसपेशियों में असहनीय दर्द हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और लीवर की समस्या हो सकती है। अन्य दवाओं के साथ लेने से पहले डॉक्टर को बताएं, खासकर खून पतला करने वाली दवाएं। गर्भावस्था या स्तनपान के दौरान इस दवा का सेवन न करें। नियमित रूप से लीवर फंक्शन और लिपिड प्रोफाइल की जांच कराएं। यदि आपको असामान्य रक्तस्राव, मांसपेशियों में दर्द या पीलिया हो, तो तुरंत डॉक्टर से संपर्क करें।
💊 atorvatin ap 20/75 capsule Uses & Benefits
[{"condition":"Secondary prevention of cardiovascular events","description":"Reduces the risk of heart attack, stroke, and death in patients with established coronary artery disease, peripheral artery disease, or prior ischemic stroke.","evidence":"Well-established"},{"condition":"Primary prevention in high-risk individuals","description":"May be used in patients with multiple risk factors such as diabetes, hypertension, and dyslipidemia to reduce the risk of first cardiovascular event.","evidence":"Moderate"},{"condition":"Hypercholesterolemia","description":"Lowers LDL cholesterol and triglycerides while increasing HDL cholesterol in patients with elevated cholesterol levels.","evidence":"Well-established"},{"condition":"Acute coronary syndrome (post-stabilization)","description":"Used as part of long-term management after acute coronary syndrome to prevent recurrent events.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label to reduce the risk of preeclampsia in high-risk pregnancies, but this combination product is not typically used for this purpose.","evidence":"Limited"},{"condition":"Antiphospholipid syndrome","description":"Aspirin may be used off-label in combination with anticoagulants in some patients with antiphospholipid syndrome, but statin component is not standard.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention
Also treats: Hypercholesterolemia, Coronary artery disease, Ischemic stroke, Peripheral artery disease, Diabetes with dyslipidemia
📋 Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Prevego Healthcare & Research Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. However, the World Health Organization recommends statins and antiplatelet therapy for secondary prevention of cardiovascular disease in appropriate patients. This specific combination is not directly mentioned in WHO guidelines. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research recommends statins for dyslipidemia management and aspirin for secondary prevention of cardiovascular events. This fixed-dose combination may be used as per clinical judgment. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Atorvastatin selectively inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, leading to upregulation of LDL receptors and increased clearance of LDL cholesterol from the blood. Aspirin acetylates cyclooxygenase-1 (COX-1) in platelets, irreversibly inhibiting thromboxane A2 production, which is a potent vasoconstrictor and platelet aggregator. The combined effect provides both lipid lowering and antiplatelet action, addressing two major pathways in atherosclerosis and thrombosis.
Mechanism Steps
💡 How to Take atorvatin ap 20/75 capsule
Strength: Capsule containing Atorvastatin 20 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (Atorvastatin 20 mg + Aspirin 75 mg) taken orally once daily, preferably in the evening. However, the dose may vary based on the indication, patient's lipid profile, cardiovascular risk, and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially bleeding risk and muscle side effects. The dose should be individualized by a clinician based on renal and hepatic function and overall health status. Regular monitoring is advised. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed. However, in severe renal impairment (creatinine clearance <30 mL/min), aspirin should be avoided due to increased risk of bleeding and renal toxicity. Atorvastatin does not require dose adjustment in renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Atorvastatin is contraindicated in patients with active liver disease or unexplained persistent elevations of liver enzymes. In patients with mild to moderate hepatic impairment, dose reduction may be considered. Aspirin should be used with caution in patients with severe liver disease due to increased bleeding risk. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose for this specific combination is one capsule (Atorvastatin 20 mg + Aspirin 75 mg) once daily. Higher doses of atorvastatin (up to 80 mg) may be prescribed by a doctor for severe hypercholesterolemia, but this combination product is fixed at 20 mg/75 mg. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of atorvatin ap 20/75 capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Clopidogrel | Major | |
| Cyclosporine | Major | |
| Clarithromycin | Moderate | |
| Itraconazole | Moderate | |
| Gemfibrozil | Moderate | |
| Methotrexate | Moderate | |
| Grapefruit juice | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other anticoagulants (e.g., heparin, dabigatran)
- NSAIDs (e.g., ibuprofen, naproxen)
- Clopidogrel
- Cyclosporine
⚡ Moderate Interactions
- Grapefruit juice
- Clarithromycin
- Itraconazole
- Gemfibrozil
- Methotrexate
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It increases the risk of gastrointestinal bleeding due to aspirin and can worsen liver toxicity from atorvastatin. Chronic alcohol use may also reduce the effectiveness of atorvastatin and increase the risk of muscle side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding or bleeding disorders","History of aspirin-sensitive asthma or allergic reaction to aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe liver disease or unexplained persistent elevations of liver enzymes","Pregnancy (especially third trimester) and breastfeeding","Children under 16 years (risk of Reye's syndrome with aspirin)","Concomitant use with live vaccines","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Inform your doctor if you have a history of stomach ulcers or bleeding.","Avoid alcohol consumption as it increases the risk of liver and stomach problems.","Tell your doctor about all other medications, especially blood thinners and NSAIDs.","Do not take this medicine if you are pregnant or planning pregnancy without consulting your doctor.","Use caution when driving or operating machinery if you experience dizziness.","Report any unusual muscle pain, weakness, or dark urine immediately.","Regular monitoring of liver function and lipid profile is required.","This medicine may increase the risk of new-onset diabetes; monitor blood sugar.","Do not stop this medicine abruptly without medical advice.","Inform your dentist or surgeon about this medicine before any procedure."]
🤱 Lactation Safety
Atorvastatin is contraindicated during breastfeeding as it may harm the infant. Aspirin is excreted in breast milk and may cause adverse effects in the infant. This combination is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this combination may cause salicylate toxicity (tinnitus, hyperventilation, metabolic acidosis, hypoglycemia) and atorvastatin toxicity (muscle pain, liver damage). Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be given if within 1-2 hours of ingestion. Monitor vital signs, blood glucose, electrolytes, and liver and kidney function. Hemodialysis may be considered for severe salicylate poisoning.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop it without medical advice. Inform your doctor if you have a history of stomach ulcers, bleeding disorders, asthma, or liver or kidney disease. Avoid alcohol while on this medicine as it increases the risk of stomach bleeding and liver problems. Tell your doctor about all other medicines you take, especially blood thinners, other antiplatelet drugs, and certain antibiotics. Use caution with activities that increase bleeding risk. Regular blood tests for liver function and lipid levels may be needed. If you are scheduled for surgery or dental work, inform your healthcare provider about this medicine. Do not take this medicine if you are pregnant or planning pregnancy without consulting your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, muscle toxicity, and liver enzyme abnormalities. The dose should be individualized, and regular monitoring is essential. Falls and bleeding precautions should be taken.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and in women planning pregnancy. If you are planning pregnancy, consult your doctor to switch to alternative treatments. Use effective contraception while on this medicine. If you become pregnant, stop the medicine immediately and contact your doctor.
🏥 Post-Surgery Considerations
Inform your surgeon about this medicine before any surgery. It may need to be stopped 5-7 days before surgery due to increased bleeding risk. Do not restart without your surgeon's advice. Your doctor may prescribe alternative medications during this period.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It increases bleeding risk during dental work. Your dentist may recommend stopping it temporarily or taking precautions. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid activities that increase the risk of injury or bleeding, such as contact sports, while on this medicine. If you experience muscle pain or weakness, stop exercising and consult your doctor. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness, muscle pain, or unusual bleeding, avoid driving or operating heavy machinery and consult your doctor. Inform your employer about your condition if your work involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. It is usually a long-term treatment. Your doctor may consider stopping it if you develop serious side effects such as severe bleeding, liver injury, or rhabdomyolysis, or if your cardiovascular risk profile changes. Always seek medical advice before discontinuation.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and beneficial for cardiovascular risk reduction. However, it may increase the risk of new-onset diabetes, gastrointestinal bleeding, and liver enzyme abnormalities. Regular monitoring of liver function, lipid profile, and blood sugar is recommended. Some patients may experience muscle aches. The benefits of preventing heart attack and stroke generally outweigh the risks. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can help control cholesterol and reduce cardiovascular risk.
Evidence: Well-establishedRosuvastatin or simvastatin may be alternatives if atorvastatin is not tolerated.
Evidence: Well-establishedClopidogrel may be used if aspirin is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, live vaccines should be avoided in patients on immunosuppressive doses of statins, though this is rare. Consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Carry enough supply for your entire trip plus extra in case of delays. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Atorvastatin begins to lower cholesterol within 2 weeks, with maximal effect in 4-6 weeks. Aspirin's antiplatelet effect starts within 30-60 minutes. However, the full cardiovascular benefit may take months to years of consistent use.
A: No, do not stop this medicine without consulting your doctor. It is a long-term preventive medicine. Stopping it can increase your risk of heart attack and stroke.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided while taking this medicine as it increases the risk of gastrointestinal bleeding and liver toxicity.
A: This medicine is contraindicated during pregnancy, especially in the third trimester. Consult your doctor for alternative treatments if you are pregnant or planning pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for atorvatin ap 20/75 capsule
View AllAlternative brands with exact same active ingredient:
-
atorise asp 20mg/75mg capsuleCarise Pharmaceuticals Pvt Ltd ₹20.00 22.4% CHEAPER
-
davaindia atorvastatin+aspirin 20mg/75mg capsuleDavaindia Generic Pharmacy ₹20.00 22.4% CHEAPER
-
biotor asp 20mg/75mg capsuleLividus Pharmaceuticals Pvt Ltd ₹24.38 5.4% CHEAPER
-
modlip-asg 20 capsuleTorrent Pharmaceuticals Ltd ₹38.35 48.8% COSTLIER
-
atorlip-asp 20 capsuleCipla Ltd ₹40.24 56.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of chest pain.
Fact: This medicine is not for acute chest pain. It is for long-term prevention of cardiovascular events. Acute chest pain requires emergency medical attention. - Myth: Once cholesterol is normal, this medicine can be stopped.
Fact: Cholesterol levels may normalize due to the medicine, but stopping it can cause cholesterol to rise again and increase cardiovascular risk. Always consult your doctor before stopping. - Myth: This medicine can be taken with any other painkiller.
Fact: Taking other NSAIDs with this medicine increases the risk of stomach bleeding and may reduce the heart-protective effect of aspirin. Always consult your doctor. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is contraindicated during pregnancy, especially in the third trimester, as it can harm the baby. Consult your doctor for alternatives.
🔄 Alternative Options
Generic Alternatives
- Atorvastatin 20 mg + Aspirin 75 mg capsule (various manufacturers)
Brand Alternatives
- Atorlip-ASP 20 capsule
- Atorva ASP 20 capsule
- Storvas ASP 20 capsule
- Lipvas ASP 20 capsule