atorvatin ap 20/75 capsule
What is atorvatin ap 20/75 capsule used for?
Aztor Asp 75 Capsule (Atorvastatin + Aspirin) is used to treat CARDIAC. It contains Atorvastatin (20mg) + Aspirin (75mg), which Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspiri. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Prevego Healthcare & Research Private Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ atorvatin ap 20/75 capsule Uses & Benefits
Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and at risk of thrombotic events.
Off-label uses: Not applicable.
๐ Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Prevego Healthcare & Research Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin: Irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 production and platelet aggregation.
Mechanism Steps
๐ก How to Take atorvatin ap 20/75 capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of atorvatin ap 20/75 capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Muscle pain
- Dyspepsia
- Increased liver enzymes
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Myopathy
- Pancreatitis
- Thrombocytopenia
- Interstitial lung disease
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ciclosporin | Major | Increased atorvastatin levels and risk of myopathy |
| Clarithromycin | Major | Increased atorvastatin levels and risk of myopathy |
| Itraconazole | Major | Increased atorvastatin levels and risk of myopathy |
| HIV protease inhibitors | Major | Increased atorvastatin levels and risk of myopathy |
| Methotrexate | Major | Increased methotrexate toxicity |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Moderate | Increased contraceptive levels |
| Colchicine | Moderate | Increased risk of myopathy |
| Antacids | Moderate | Reduced atorvastatin absorption |
| Fibrates | Moderate | Increased risk of myopathy |
| Niacin | Moderate | Increased risk of myopathy |
| Grapefruit juice | Minor | Increased atorvastatin levels |
| Vitamin K antagonists (low dose) | Minor | Minor INR changes |
| Spironolactone | Minor | Reduced diuretic effect |
๐จ Major Interactions
- Warfarin
- Ciclosporin
- Clarithromycin
- Itraconazole
- HIV protease inhibitors
- Methotrexate
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Antacids
- Fibrates
- Niacin
โน๏ธ Minor Interactions
- Grapefruit juice
- Vitamin K antagonists (low dose)
- Spironolactone
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; avoid high-fat meals with aspirin.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding with aspirin; alcohol may affect atorvastatin metabolism.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent liver enzyme elevations, pregnancy, breastfeeding, active peptic ulcer, bleeding disorders, hypersensitivity to any component.
๐ Monitoring Parameters
Liver function tests, lipid profile, renal function, signs of bleeding, INR if on warfarin.
๐คฑ Lactation Safety
Atorvastatin: Not recommended; Aspirin: Excreted in breast milk, avoid high doses.
๐ Overdose Management
Symptomatic and supportive care; for aspirin overdose, consider gastric lavage, activated charcoal, and hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Effective and reliable. Worked as expected.