Drotin Injection 2ml: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe chest pain or irregular heartbeat
- Extreme dizziness or fainting
- Persistent vomiting or severe abdominal pain
- Signs of an allergic reaction such as rash, itching, or hives
- Decreased urine output or blood in urine
If experiencing severe symptoms, call emergency services immediately.
What is pdspas 40mg injection used for?
Drotaverine injection is an antispasmodic medicine used to relieve smooth muscle spasms in conditions like gastrointestinal, biliary, and renal colic, as well as dysmenorrhea. It works by relaxing smooth muscles and is given by a healthcare professional.
- Generic Name: Drotaverine (40mg)
- Manufacturer: Pharma Drugs & Chemicals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pdspas 40mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा ड्रोटावेरिन हाइड्रोक्लोराइड का इंजेक्शन है, जिसका उपयोग पेट, पित्त नली, गुर्दे और गर्भाशय की मांसपेशियों में होने वाले ऐंठन को दूर करने के लिए किया जाता है। यह दवा मांसपेशियों को आराम देकर दर्द को कम करती है। इसे डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दिया जाता है। यह दवा पेट दर्द, पित्त की पथरी, गुर्दे की पथरी और मासिक धर्म के दर्द में राहत देती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन, चक्कर आना, सिरदर्द, जी मिचलाना और रक्तचाप कम होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में कठिनाई, चेहरे या गले में सूजन, या दिल की धड़कन अनियमित हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इंजेक्शन लगने के बाद तब तक वाहन न चलाएं जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।
💊 pdspas 40mg injection Uses & Benefits
[{"condition":"Gastrointestinal spasms","description":"Relieves painful spasms of the stomach and intestines, often associated with irritable bowel syndrome or gastroenteritis.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Relaxes the smooth muscle of the biliary tract to relieve pain from gallstones or biliary dyskinesia.","evidence":"Well-established"},{"condition":"Renal colic","description":"Reduces spasms in the urinary tract, helping to relieve pain from kidney stones.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps by relaxing uterine smooth muscle.","evidence":"Well-established"},{"condition":"Labor pain management","description":"Sometimes used to reduce cervical spasms during labor, but only under strict medical supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Esophageal spasm","description":"May be used off-label to relieve spasm of the esophagus, but evidence is limited.","evidence":"Limited"},{"condition":"Tension headache","description":"Occasionally used off-label for tension-type headaches, though not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Smooth muscle spasms
Also treats: Gastrointestinal spasms, Biliary colic, Renal colic, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Drotaverine (40mg) |
| Brand Name | pdspas 40mg injection |
| Manufacturer | Pharma Drugs & Chemicals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Phosphodiesterase-IV inhibitors (Smooth Muscle Relaxant) |
| Route of Administration | Parenteral (intramuscular or intravenous injection) |
| Storage | Store below 30°C in a dry place, protected from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Drotaverine inhibits phosphodiesterase type 4 (PDE4), leading to increased intracellular cyclic adenosine monophosphate (cAMP) in smooth muscle cells. Elevated cAMP reduces calcium availability and inhibits myosin light-chain kinase, resulting in smooth muscle relaxation. This action is selective for smooth muscle and does not significantly affect cardiac muscle or skeletal muscle.
Mechanism Steps
💡 How to Take pdspas 40mg injection
Strength: Injection: 40 mg in 2 ml ampoule
Dosage Information
| Adult Dosage | The usual adult dose is 40 mg to 80 mg given by intramuscular or intravenous injection, up to three times daily. The maximum daily dose is 240 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of drotaverine, especially hypotension and dizziness. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with severe renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | 240 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pdspas 40mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Levodopa | Major | |
| Anticholinergics | Moderate | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Levodopa
- Anticholinergic drugs (e.g., atropine, hyoscine)
⚡ Moderate Interactions
- Beta-blockers
- Calcium channel blockers
🍷 Alcohol Interaction
Alcohol may enhance the central nervous system depressant effects of drotaverine, such as dizziness and drowsiness. It is advisable to avoid alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to drotaverine or any component of the formulation","Severe heart failure","Severe liver disease","Severe kidney disease","Children under 12 years of age (safety and efficacy not established)"]
⚠️ Warnings & Precautions
["This medicine should be administered only by a healthcare professional.","Use with caution in patients with low blood pressure or heart disease.","Avoid driving or operating machinery after receiving this injection until you know how it affects you.","Do not use if the solution is discolored or contains particles.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether drotaverine is excreted in human breast milk. Caution is advised when used in breastfeeding women. Consult a doctor before use.
💊 Overdose Management
Overdose may cause severe hypotension, tachycardia, and central nervous system depression. There is no specific antidote. Treatment is supportive and symptomatic, including monitoring of vital signs and administration of intravenous fluids if needed. In case of overdose, seek immediate medical attention.
⏰ Missed Dose
This medicine is given by a healthcare professional, so missed doses are unlikely. If you miss a scheduled dose, contact your doctor or nurse for guidance. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a clinical setting. Do not attempt to self-administer. Inform your doctor about all your medical conditions, especially heart, liver, or kidney problems, and all medicines you are taking. Avoid driving or operating machinery immediately after receiving this injection until you know how it affects you. Do not use this medicine if you are allergic to drotaverine or any of its ingredients. Use with caution in elderly patients and those with low blood pressure.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the hypotensive and dizzy effects of this medicine. Use with caution and monitor blood pressure closely. Lower doses may be appropriate.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to relieve smooth muscle spasms. However, it should be administered only under medical supervision. Inform your surgeon if you are taking this medicine.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist if you are receiving this medicine, as it may interact with other medications used during dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after receiving this injection, as it may cause dizziness or low blood pressure. Rest for at least 30 minutes before resuming normal activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness and low blood pressure, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is usually given in a clinical setting, so work impact is minimal after the effect wears off.
🛑 When to Stop This Medicine
This medicine is given as a single dose or a short course. Do not stop or change the dose without consulting your doctor. If you experience severe side effects, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance and increased risk of side effects. Regular monitoring of liver and kidney function may be advised. Consult your doctor for periodic evaluation.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Oral drotaverine or other antispasmodics can be used for milder spasms.
Evidence: Well-establishedApplying a heating pad to the abdomen can help relax muscles.
Evidence: LimitedDeep breathing and meditation can reduce stress-related spasms.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine if you are currently receiving this medicine.
📦 Storage Guide
✅ DO
Store below 30°C in a dry place
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if the solution is discolored or contains particles
✅ DO
Keep out of reach of children
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional, so it is not typically carried by patients during travel. If you are prescribed this medicine for use during travel, carry it in its original packaging with a copy of your prescription. Store it below 30°C and protect it from light. Check customs regulations for injectable medicines before traveling internationally. It is advisable to have a doctor's letter explaining the medical need.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 5 to 15 minutes after injection.
A: No, this medicine must be given by a healthcare professional in a clinical setting.
A: Use during pregnancy only if clearly needed and after consulting your doctor.
A: Common side effects include injection site pain, dizziness, headache, and nausea.
🤔 Common Patient Concerns
🔄 Substitutes for pdspas 40mg injection
View AllAlternative brands with exact same active ingredient:
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inorine 40mg injectionInd Swift Laboratories Ltd ₹8.18 65.1% CHEAPER
-
drot 40mg injectionMapra Laboratories Pvt Ltd ₹9.95 57.6% CHEAPER
-
Smoothspas 40mg InjectionP R G Pharma Pvt Ltd ₹10.31 56% CHEAPER
-
Rotaspas 40mg InjectionBiological E Ltd ₹10.85 53.7% CHEAPER
-
abdocin 40mg injectionAltar Healthcare Pvt Ltd ₹11.00 53.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Drotaverine injection is a painkiller for any type of pain.
Fact: It is specifically for smooth muscle spasms and is not effective for other types of pain. - Myth: You can self-administer drotaverine injection at home.
Fact: It must be given by a healthcare professional in a clinical setting. - Myth: Drotaverine injection is safe during pregnancy without any risk.
Fact: It should be used during pregnancy only if clearly needed and after consulting a doctor.
🔄 Alternative Options
Generic Alternatives
- Drotaverine 40 mg/2 ml injection
Brand Alternatives
- Drotin Injection 2ml