Emetil 50mg Tablet (Chlorpromazine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with severe muscle stiffness or confusion
- Irregular heartbeat or palpitations
- Fever, sore throat, or mouth ulcers
- Yellowing of skin or eyes
- Severe dizziness or fainting
- Involuntary movements of face, tongue, or limbs
- Difficulty breathing or swallowing
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is ostil 50mg tablet used for?
This medicine is a phenothiazine antipsychotic used to treat schizophrenia, acute mania, and severe nausea and vomiting. It works by blocking dopamine receptors in the brain. It is a prescription-only medicine and must be used under medical supervision.
- Generic Name: Chlorpromazine (50mg)
- Manufacturer: Osho Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ostil 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरप्रोमाज़ीन नामक सक्रिय तत्व से बनी है और मुख्य रूप से सिज़ोफ्रेनिया, तीव्र मेनिया और गंभीर मतली और उल्टी के इलाज के लिए इस्तेमाल की जाती है। यह मस्तिष्क में डोपामाइन रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे मतिभ्रम और भ्रम कम होते हैं। यह दवा लगातार हिचकी में भी प्रभावी हो सकती है। यह केवल डॉक्टर के पर्चे पर मिलती है और इसका सेवन चिकित्सक की देखरेख में ही करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि, कब्ज और वजन बढ़ना शामिल हैं। कुछ रोगियों में मांसपेशियों में अकड़न, कंपन और चलने में कठिनाई हो सकती है। दुर्लभ लेकिन गंभीर दुष्प्रभावों में न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम, रक्त विकार और हृदय की अनियमित धड़कन शामिल हैं। यदि आपको तेज बुखार, गंभीर मांसपेशियों में अकड़न, भ्रम, या संक्रमण के लक्षण जैसे गले में खराश या मुँह के छाले हों, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल योग्य चिकित्सक की सलाह पर ही लें। इसे अचानक बंद न करें, क्योंकि इससे वापसी के लक्षण या बीमारी का दोबारा होना हो सकता है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या भारी मशीनरी चलाने से बचें। इस दवा के साथ शराब न पिएं। यदि आपको हृदय, यकृत, गुर्दे, पार्किंसन रोग या ग्लूकोमा की समस्या है, तो अपने डॉक्टर को बताएं। धूप में बाहर निकलते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। नियमित रक्त परीक्षण और हृदय की निगरानी की आवश्यकता हो सकती है।
💊 ostil 50mg tablet Uses & Benefits
[{"condition":"Schizophrenia","description":"This medicine helps reduce hallucinations, delusions, and disorganized thinking in patients with schizophrenia.","evidence":"Well-established"},{"condition":"Acute mania","description":"It is used to control severe agitation and manic episodes in bipolar disorder.","evidence":"Well-established"},{"condition":"Severe nausea and vomiting","description":"This medicine is effective in treating severe nausea and vomiting from various causes, including chemotherapy and surgery.","evidence":"Well-established"},{"condition":"Intractable hiccups","description":"It can be used to treat persistent hiccups that do not respond to other measures.","evidence":"Limited"},{"condition":"Severe anxiety","description":"Short-term use may be considered for severe anxiety when other treatments have failed.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine headache","description":"Sometimes used in emergency settings to treat acute migraine attacks.","evidence":"Limited"},{"condition":"Porphyria","description":"May be used to manage acute attacks of porphyria, but only under specialist care.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Bipolar disorder, Severe nausea and vomiting, Intractable hiccups
📋 Drug Information
| Generic Name(s) | Chlorpromazine (50mg) |
| Brand Name | ostil 50mg tablet |
| Manufacturer | Osho Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Typical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Chlorpromazine is included in the WHO Model List of Essential Medicines for the treatment of psychotic disorders. It is recommended for use in resource-limited settings. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) recognizes chlorpromazine as a first-generation antipsychotic for the management of schizophrenia and related psychotic disorders. It should be used under specialist supervision. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking dopamine D2 receptors in the brain, particularly in the mesolimbic and mesocortical pathways, which helps reduce psychotic symptoms. It also blocks serotonin 5-HT2 receptors, alpha-adrenergic receptors, histamine H1 receptors, and muscarinic acetylcholine receptors. This broad receptor blockade explains both its therapeutic effects and many of its side effects. The antiemetic effect is due to dopamine blockade in the chemoreceptor trigger zone of the medulla oblongata.
Mechanism Steps
💡 How to Take ostil 50mg tablet
Strength: 50 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for psychiatric conditions ranges from 25 mg to 100 mg taken two to four times daily, but the exact dose depends on the condition being treated and the patient's response. For nausea and vomiting, a lower dose such as 10 mg to 25 mg every 4 to 6 hours may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of this medicine, especially sedation, hypotension, and extrapyramidal symptoms. Lower initial doses are recommended, and the dose should be increased gradually. Close monitoring is required. |
| Renal Impairment | This medicine should be used with caution in patients with renal impairment. Dose adjustment may be necessary, but specific guidelines are not established from the available information. Consult a clinician. |
| Hepatic Impairment | This medicine should be used with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose for adults is not established from the available information and depends on the indication and patient response. It should not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ostil 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| CNS depressants | Major | |
| QT-prolonging drugs | Major | |
| Levodopa | Major | |
| Anticholinergics | Major | |
| Beta-blockers | Moderate | |
| Lithium | Moderate | |
| Metoclopramide | Moderate | |
| Antacids | Moderate | |
| Caffeine | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Central nervous system depressants (e.g., alcohol, benzodiazepines, opioids)
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Levodopa
- Anticholinergic drugs (e.g., benztropine, trihexyphenidyl)
⚡ Moderate Interactions
- Beta-blockers
- Lithium
- Metoclopramide
- Antacids
- Caffeine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of low blood pressure. It can also worsen the sedative effects and impair your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpromazine or other phenothiazines","Severe cardiovascular disease","Severe liver disease","Blood dyscrasias","Parkinson's disease","Glaucoma","Prostatic hypertrophy with urinary retention","Concomitant use with MAOIs"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","May cause low blood pressure upon standing; rise slowly.","May increase sensitivity to sunlight; use sunscreen.","May cause extrapyramidal symptoms; report any muscle stiffness or tremors.","May cause tardive dyskinesia with long-term use; report any involuntary movements.","May cause neuroleptic malignant syndrome; seek immediate medical attention for high fever, muscle rigidity, or confusion.","May cause blood disorders; report fever, sore throat, or mouth ulcers.","Use with caution in elderly patients with dementia; increased risk of death.","May impair judgment and thinking; use caution with activities requiring alertness."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause drowsiness and other side effects in the nursing infant. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, coma, low blood pressure, irregular heartbeat, and seizures. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, intravenous fluids, and medications to control seizures and arrhythmias. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
This medicine should only be taken under the supervision of a qualified clinician. Do not stop taking this medicine suddenly, as this can cause withdrawal symptoms or a relapse of your condition. Avoid driving or operating heavy machinery until you know how this medicine affects you, because it can cause drowsiness and slow your reactions. Do not drink alcohol while taking this medicine, as it can increase drowsiness and affect your blood pressure. Inform your doctor if you have a history of heart problems, liver disease, kidney disease, Parkinson's disease, or glaucoma. This medicine can make your skin more sensitive to sunlight, so use sunscreen and protective clothing when outdoors. Regular blood tests and heart monitoring may be required during treatment. If you experience fever, sore throat, mouth ulcers, or any signs of infection, contact your doctor immediately, as these could be signs of a serious blood disorder. Keep all appointments with your healthcare provider.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine, especially sedation, low blood pressure, and extrapyramidal symptoms. There is an increased risk of death when used in elderly patients with dementia-related psychosis. Lower doses are recommended, and close monitoring is required.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Your doctor may adjust your treatment plan.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect blood pressure and heart rate. Your doctor may advise you to stop the medicine temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can cause dry mouth, which may increase the risk of dental problems. It may also interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may affect your ability to exercise safely. Avoid activities that require high alertness, such as heavy lifting or contact sports, until you know how this medicine affects you. Stay hydrated during exercise, especially in hot weather, as this medicine can reduce sweating and increase the risk of heat exhaustion.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to work, drive, or operate machinery. It is important to avoid these activities until you know how the medicine affects you. You may need to adjust your work schedule or tasks if you experience significant side effects. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will determine when and how to gradually reduce the dose based on your condition and response to treatment. Stopping suddenly can cause withdrawal symptoms or a relapse of your underlying condition.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tardive dyskinesia, a condition characterized by involuntary movements of the face, tongue, or limbs. It can also cause weight gain, diabetes, and high cholesterol. Regular monitoring of blood sugar, cholesterol, and weight is recommended. Eye examinations are advised to check for corneal deposits and lens opacities. Liver function and blood counts should be monitored periodically. The dose should be reviewed regularly by your doctor to ensure it is still appropriate.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be used alongside medication to help manage symptoms of schizophrenia and related disorders.
Evidence: Well-establishedRegular exercise, healthy diet, and stress management can complement medical treatment.
Evidence: ModeratePeer support can provide emotional encouragement and practical advice.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccinations, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, consult your doctor about adjusting your dosing schedule. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For antipsychotic effects, it may take several days to weeks to see full benefit. For nausea and vomiting, it works within 30 to 60 minutes.
A: You should inform your doctor about all other medicines you are taking, as this medicine can interact with many drugs. Do not start any new medicine without consulting your doctor.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be avoided as it can increase drowsiness, dizziness, and the risk of low blood pressure.
A: No, you should not stop taking this medicine suddenly without consulting your doctor, as it can cause withdrawal symptoms or a relapse of your condition.
🤔 Common Patient Concerns
🔄 Substitutes for ostil 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
clozine 50mg tabletPsychotropics India Ltd ₹3.52 6.1% CHEAPER
-
prozine 50mg tabletShine Pharmaceuticals Ltd ₹3.72 0.8% CHEAPER
-
chlorpro 50mg tabletPsycormedies ₹3.75 SAME PRICE
-
Trytil 50mg TabletS P Pharma ₹3.86 2.9% COSTLIER
-
zinetil 50mg tabletGujarat Terce Laboratories Ltd ₹3.96 5.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is only for severe mental illness.
Fact: It is also used for severe nausea and vomiting and persistent hiccups. - Myth: This medicine is addictive.
Fact: It is not addictive, but it can cause dependence and withdrawal symptoms if stopped suddenly. - Myth: You can stop taking this medicine once you feel better.
Fact: Stopping suddenly can cause relapse or withdrawal symptoms. Always consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Chlorpromazine 50 mg tablet
Brand Alternatives
- Emetil 50 mg tablet