chlorpro 50mg tablet - Chlorpromazine (50mg) medicine

chlorpro 50mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Psycormedies ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is chlorpro 50mg tablet used for?

Chlorpromazine 50mg Tablet (Chlorpromazine) is used to treat NEURO CNS. It contains Chlorpromazine (50mg), which Blocks dopamine D2 receptors in the mesolimbic pathway; also blocks alpha-adrene. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chlorpromazine
  • Manufacturer: Psycormedies
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š chlorpro 50mg tablet Uses & Benefits

Schizophrenia, bipolar disorder (mania), severe anxiety, nausea/vomiting, intractable hiccups, acute intermittent porphyria, preoperative sedation

Off-label uses: Tourette syndrome, Huntington's disease, chronic pain, migraine prophylaxis, pruritus, anxiety disorders

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorpromazine
Brand NameChlorpromazine 50mg Tablet
ManufacturerPsycormedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassTypical Antipsychotics
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration in 2-4 hours
DistributionWidely distributed; crosses blood-brain barrier; high volume of distribution (10-20 L/kg)
Protein Binding90-99% bound to plasma proteins
MetabolismExtensively metabolized in liver via CYP2D6, CYP1A2, and other pathways; major metabolites include 7-hydroxychlorpromazine and chlorpromazine sulfoxide
Half-Life20-40 hours (biphasic); terminal half-life up to 30 hours
ExcretionPrimarily renal (70-80% as metabolites); small amount in feces
BioavailabilityOral bioavailability approximately 30-50% due to first-pass metabolism
Onset of Action30-60 minutes after oral administration
Peak Plasma Time2-4 hours
Duration of Action4-6 hours for antipsychotic effect; longer for sedative effects

How It Works

Blocks dopamine D2 receptors in the mesolimbic pathway; also blocks alpha-adrenergic, histaminergic, and muscarinic receptors

Mechanism Steps

1Blocks dopamine D2 receptors in the mesolimbic system, reducing positive symptoms of psychosis
2Blocks alpha-1 adrenergic receptors, causing sedation and hypotension
3Blocks H1 histamine receptors, contributing to sedation and weight gain

๐Ÿ’ก How to Take chlorpro 50mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of chlorpro 50mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Constipation
  • Blurred vision
  • Weight gain
  • Orthostatic hypotension
  • Nasal congestion

๐Ÿšจ Serious Side Effects

  • Tardive dyskinesia
  • Neuroleptic malignant syndrome
  • Seizures
  • QT prolongation
  • Agranulocytosis
  • Cholestatic jaundice
  • Severe hypotension

โš ๏ธ Rare Side Effects

  • Photosensitivity
  • Skin pigmentation
  • Galactorrhea
  • Amenorrhea
  • Priapism
  • Allergic reactions
  • Lupus-like syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Increased CNS depression and sedation
Levodopa Major Antagonism of levodopa effect
QT-prolonging drugs Major Increased risk of QT prolongation and arrhythmias
Anticholinergics Major Additive anticholinergic effects
Lithium Major Increased risk of neurotoxicity
Antihypertensives Major Additive hypotensive effect
CNS depressants Major Enhanced sedation and respiratory depression
CYP2D6 inhibitors Moderate Increased chlorpromazine levels
CYP1A2 inhibitors Moderate Increased chlorpromazine levels
Antiepileptics Moderate May lower seizure threshold
Anticoagulants Moderate May alter anticoagulant effect
Beta-blockers Moderate Increased risk of hypotension
Antacids Minor Decreased absorption of chlorpromazine
Smoking Minor Increased metabolism, reduced efficacy
Caffeine Minor Possible decreased sedative effect

๐Ÿšจ Major Interactions

  • Alcohol
  • CNS depressants
  • Anticholinergics
  • Lithium
  • Antihypertensives
  • Levodopa
  • QT-prolonging drugs

โšก Moderate Interactions

  • CYP2D6 inhibitors
  • CYP1A2 inhibitors
  • Antiepileptics
  • Anticoagulants
  • Beta-blockers

โ„น๏ธ Minor Interactions

  • Antacids
  • Smoking
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; avoid grapefruit juice (may increase levels)

๐Ÿท Alcohol Interaction

Enhanced CNS depression; avoid alcohol

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to chlorpromazine or phenothiazines; coma; severe CNS depression; bone marrow suppression; pheochromocytoma; concurrent use of high-dose CNS depressants

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, ECG (QT interval), liver function tests, CBC, mental status, extrapyramidal symptoms, weight, blood glucose

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk; may cause sedation and extrapyramidal effects in infant

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor ECG, vital signs; treat hypotension with IV fluids and vasopressors; treat seizures with benzodiazepines; avoid epinephrine

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for chlorpro 50mg tablet

View All

Alternative brands with exact same active ingredient (Chlorpromazine (50mg)):

Medical Note: Always consult your doctor before switching medications.

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