Aconlax MZS Oral Suspension: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Tendon pain or swelling
- Tingling or numbness in hands or feet
- Seizures or loss of consciousness
If experiencing severe symptoms, call emergency services immediately.
What is oftros-m oral suspension used for?
This medicine is a combination antibiotic oral suspension containing ofloxacin and metronidazole. It is used to treat mixed bacterial and anaerobic infections, such as infectious diarrhea, dysentery, and intra-abdominal infections. It works by killing bacteria and must be taken exactly as prescribed.
- Generic Name: Ofloxacin (50mg/5ml) + Metronidazole (120mg/5ml)
- Manufacturer: MRG Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 oftros-m oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और मेट्रोनिडाजोल का संयोजन है, जिसका उपयोग बैक्टीरियल और एनारोबिक संक्रमणों के इलाज के लिए किया जाता है। यह दस्त, पेचिश, पेट के संक्रमण, स्त्री रोग संबंधी संक्रमण और दांतों के फोड़े के इलाज में प्रभावी है। यह दवा बैक्टीरिया को मारकर काम करती है और इसे डॉक्टर के निर्देशानुसार पूरा कोर्स लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और मुंह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, टेंडन टूटना, नसों में झुनझुनी और गंभीर दस्त हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। हर बार लेने से पहले बोतल को अच्छी तरह हिलाएं। सही मात्रा मापने के लिए दी गई मापने वाली कप या चम्मच का उपयोग करें। कोर्स पूरा करें, बीच में न छोड़ें। शराब बिल्कुल न लें क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है। धूप से बचें और सनस्क्रीन का उपयोग करें।
💊 oftros-m oral suspension Uses & Benefits
[{"condition":"Infectious diarrhea and dysentery","description":"Used to treat diarrhea caused by mixed bacterial and anaerobic pathogens, including Shigella, Salmonella, and Entamoeba histolytica.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Prescribed for infections such as peritonitis, appendicitis with rupture, and liver abscesses where both aerobic and anaerobic bacteria are involved.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Used for pelvic inflammatory disease, bacterial vaginosis, and trichomoniasis when combined therapy is needed.","evidence":"Well-established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and periodontal infections caused by mixed oral flora.","evidence":"Moderate"},{"condition":"Skin and soft tissue infections","description":"May be used for infected wounds or abscesses when anaerobic coverage is required.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, though not a first-line choice.","evidence":"Limited"},{"condition":"Prophylaxis in colorectal surgery","description":"Occasionally used to prevent postoperative infections in colorectal procedures.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and anaerobic infections
Also treats: Infectious diarrhea, Dysentery, Intra-abdominal infections, Pelvic inflammatory disease, Bacterial vaginosis, Dental abscess
📋 Drug Information
| Generic Name(s) | Ofloxacin (50mg/5ml) + Metronidazole (120mg/5ml) |
| Brand Name | oftros-m oral suspension |
| Manufacturer | MRG Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed. Shake well before each use. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with different mechanisms. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication, repair, and transcription, leading to bacterial cell death. Metronidazole enters anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA and inhibit nucleic acid synthesis. Together, they provide broad coverage against aerobic gram-negative bacteria and anaerobic organisms.
Mechanism Steps
💡 How to Take oftros-m oral suspension
Strength: Each 5 ml of oral suspension contains Ofloxacin 50 mg and Metronidazole 120 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 ml to 10 ml taken orally twice daily, or as directed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Complete the full course even if you feel better. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 18 years due to the risk of joint and tendon problems associated with fluoroquinolones. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially tendon problems, kidney effects, and central nervous system effects. Dose adjustment may be needed based on kidney function. Use with caution and monitor closely. |
| Renal Impairment | Dose adjustment is required in patients with reduced kidney function. Ofloxacin is primarily excreted by the kidneys, and accumulation can increase the risk of side effects. Consult your doctor for appropriate dose adjustment based on creatinine clearance. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe liver disease. Metronidazole is metabolized in the liver, and its clearance may be reduced. Monitor liver function and adjust dose as advised by your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescribed amount. For adults, typical maximum is 20 ml per day of this suspension, but this must be confirmed by your doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of oftros-m oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Antacids | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Cimetidine | Moderate | |
| Lithium | Moderate | |
| Phenytoin | Moderate | |
| Cyclosporine | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Antacids containing aluminum or magnesium
- Theophylline
- NSAIDs
⚡ Moderate Interactions
- Cimetidine
- Lithium
- Phenytoin
- Cyclosporine
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least 48 hours after the last dose. Metronidazole can cause a disulfiram-like reaction with alcohol, leading to flushing, severe nausea, vomiting, headache, and rapid heartbeat. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to ofloxacin, metronidazole, or other fluoroquinolones or nitroimidazoles.","Children under 18 years of age, except when specifically approved by a specialist.","Pregnancy and breastfeeding.","History of tendon disorders related to fluoroquinolone use.","Myasthenia gravis (may worsen muscle weakness).","Severe liver disease.","Alcohol consumption during treatment and for 48 hours after."]
⚠️ Warnings & Precautions
["Fluoroquinolones, including ofloxacin, can cause tendon inflammation and rupture, especially in older adults, those with kidney disease, or those on corticosteroids. Stop the medicine and contact your doctor if you experience tendon pain.","Ofloxacin can cause peripheral neuropathy. Report tingling, numbness, or burning in hands or feet immediately.","Metronidazole can cause seizures and encephalopathy rarely. Use with caution in patients with CNS disorders.","This medicine may cause dizziness and affect alertness. Avoid driving or operating machinery until you know how it affects you.","Avoid excessive sunlight and use sunscreen because ofloxacin can cause photosensitivity.","Do not use this medicine for viral infections like colds or flu; it will not help and may cause harm.","Complete the full course as prescribed to prevent antibiotic resistance."]
🤱 Lactation Safety
This medicine passes into breast milk. It is not recommended during breastfeeding because of potential risks to the infant, including joint problems and effects on the developing nervous system. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, dizziness, and in severe cases, seizures or heart rhythm problems. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs, ECG, and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. Try to take doses at evenly spaced intervals.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each dose to ensure the medicine is evenly mixed. Use a proper measuring cup or spoon provided with the product, not a household spoon, to get the correct dose. Do not skip doses or stop the course early, even if you feel better, as this can allow the infection to return and lead to antibiotic resistance. Avoid alcohol completely while taking this medicine and for at least 48 hours after the last dose, because metronidazole can cause a severe reaction with alcohol, including flushing, nausea, vomiting, and rapid heartbeat. Inform your doctor if you have kidney or liver problems, heart rhythm disorders, or a history of tendon problems. This medicine can make you dizzy or affect your concentration, so avoid driving or operating heavy machinery until you know how it affects you. Protect your skin from sunlight and use sunscreen. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney problems, and central nervous system effects from this medicine. Dose adjustment may be needed based on kidney function. Monitor closely for any signs of tendon pain, confusion, or dizziness. Ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are trying to conceive, consult your doctor for safer alternatives. Use effective contraception while taking this medicine and for at least 48 hours after the last dose.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent infections after surgery, especially intra-abdominal or gynecological procedures. Follow your surgeon's instructions carefully. Inform your surgeon if you are taking this medicine before any planned surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. This medicine may be prescribed for dental infections, but it is not a substitute for necessary dental treatment such as drainage or root canal. Continue taking it as prescribed unless your dentist advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you experience dizziness or tendon pain. If you notice any joint pain or swelling, stop exercising and consult your doctor immediately. Light activities like walking are generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or fatigue, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. If your work involves physical exertion, take breaks and stay hydrated. Inform your employer if you need to take sick leave to recover fully.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can allow the infection to return and lead to antibiotic resistance. If you experience serious side effects such as tendon pain, severe allergic reaction, or seizures, stop the medicine and seek immediate medical attention. Your doctor will advise if and when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically directed by a doctor. Prolonged use can increase the risk of antibiotic resistance, tendon problems, nerve damage, and liver or kidney effects. Regular monitoring of kidney and liver function may be needed if used for extended periods. Always complete the prescribed course and do not self-medicate for longer than advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May help restore gut flora and reduce antibiotic-associated diarrhea.
Evidence: ModerateEssential for managing dehydration from diarrhea.
Evidence: Well-establishedFor dental abscesses, antibiotics are adjunctive to definitive dental treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as typhoid vaccine. Avoid taking live vaccines during treatment and for several days after. Consult your doctor for specific timing. Inactivated vaccines are generally safe to administer.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Shake well before each use
❌ DON'T
Do not use if the suspension has changed color or consistency
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or doctor's note, especially for international travel. Keep the bottle in a cool, dry place away from direct sunlight. If traveling across time zones, maintain the dosing schedule as close to every 12 hours as possible. Do not pack it in checked luggage if you need it during the flight; keep it in your carry-on. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but you must complete the full course as prescribed, usually 5-10 days, to fully clear the infection.
A: Yes, you can take it with food. Taking it with meals may help reduce stomach upset and nausea.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, you must avoid alcohol completely during treatment and for at least 48 hours after the last dose, as it can cause a severe reaction.
A: This medicine is generally not recommended for children under 18 years due to the risk of joint and tendon problems. Consult a pediatrician for alternative treatment.
🤔 Common Patient Concerns
🔄 Substitutes for oftros-m oral suspension
View AllAlternative brands with exact same active ingredient:
-
inquflox m oral suspensionSmayan Healthcare Pvt Ltd ₹29.99 54.3% CHEAPER
-
oxloben-m oral suspensionBen Hadded Pharma Pvt Ltd ₹32.81 50% CHEAPER
-
drflox ms oral suspensionDR Best pharmaceuticals Pvt Ltd ₹35.00 46.7% CHEAPER
-
waga mz suspensionAden Healthcare ₹37.50 42.9% CHEAPER
-
oflokos m oral suspensionElkos Healthcare Pvt Ltd ₹42.19 35.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of diarrhea.
Fact: This medicine only works for specific bacterial or anaerobic infections. It does not treat viral diarrhea or diarrhea caused by other conditions. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol must be completely avoided because metronidazole can cause a severe disulfiram-like reaction with alcohol. - Myth: This medicine is safe for children.
Fact: This medicine is generally not recommended for children under 18 years due to the risk of joint and tendon problems.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin + Metronidazole oral suspension
Brand Alternatives
- Aconlax MZS Oral Suspension