Dikart-bn Cream: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of the face, lips, or throat, or difficulty breathing.
- Signs of adrenal suppression such as extreme tiredness, weakness, dizziness, or low blood pressure.
- Worsening of the skin infection with spreading redness, pain, heat, or pus.
- Eye pain, redness, or blurred vision after accidental contact with the cream.
- Yellowing of the skin or eyes, dark urine, or severe tiredness, which may indicate liver problems.
- Unexplained high blood sugar readings if you have diabetes.
- Skin thinning, stretch marks, or easy bruising that appears during treatment.
If experiencing severe symptoms, call emergency services immediately.
What is Nizowal-BN Plus Cream used for?
This medicine is a topical cream that combines ketoconazole 2% and beclometasone 0.025%. It is used for inflamed fungal skin infections such as ringworm and jock itch. Apply a thin layer once or twice daily for the duration your doctor recommends. Do not use it for long periods or on the face without medical advice.
- Generic Name: Ketoconazole (2% w/w) + Beclometasone (0.025% w/w)
- Manufacturer: Wallace Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Nizowal-BN Plus Cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें कीटोकोनाज़ोल 2% और बेक्लोमेटासोन 0.025% होता है। यह फंगल संक्रमण और उससे होने वाली सूजन, खुजली और लालिमा के इलाज के लिए इस्तेमाल की जाती है। इसे आमतौर पर दाद, खाज-खुजली और शरीर के मोड़ों पर होने वाले फंगल संक्रमण के लिए डॉक्टर की सलाह पर लगाया जाता है। इसे पतली परत में दिन में एक या दो बार लगाएं और डॉक्टर द्वारा बताई गई अवधि तक ही इस्तेमाल करें। इसे चेहरे, जांघों के बीच या बगल में लंबे समय तक न लगाएं। गर्भवती महिलाएं, स्तनपान कराने वाली माताएं और बच्चे इसे डॉक्टर की सलाह के बिना इस्तेमाल न करें।
साइड इफेक्ट्स: इस क्रीम को लगाने पर कुछ लोगों को हल्की जलन, खुजली, सूखापन या लालिमा हो सकती है। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। लंबे समय तक इस्तेमाल करने पर त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं या रंग बदल सकता है। कभी-कभी एलर्जी, संक्रमण का बढ़ना या स्टेरॉयड के अवशोषण से जुड़ी समस्याएं हो सकती हैं। अगर आपको गंभीर जलन, सूजन, सांस लेने में तकलीफ या आंखों में दर्द हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लगाएं। लगाने से पहले और बाद में हाथ धोएं। प्रभावित त्वचा को साफ और सूखा करें, फिर पतली परत में क्रीम लगाएं। आंखों, मुंह और शरीर के अन्य नाजुक हिस्सों पर न लगाएं। चेहरे, जांघों के बीच या बगल में बिना डॉक्टर की सलाह के ज्यादा दिन तक न लगाएं। गर्भावस्था, स्तनपान या बच्चों में इस्तेमाल से पहले डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर रखें। अगर कुछ दिनों में सुधार न दिखे या तकलीफ बढ़े, तो डॉक्टर से संपर्क करें।
💊 Nizowal-BN Plus Cream Uses & Benefits
[{"condition":"Inflamed tinea corporis (ringworm of the body)","description":"This medicine helps clear the fungal infection while reducing the associated redness, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and itching.","evidence":"Well-established for the combination when inflammation is prominent."},{"condition":"Tinea cruris (jock itch) with marked inflammation","description":"Used for short courses to treat the fungal infection and calm the inflamed skin in the groin area.","evidence":"Well-established, but use should be limited because the groin area absorbs steroids more readily."},{"condition":"Candidal intertrigo","description":"Helps treat Candida infection in skin folds while reducing the inflammatory reaction.","evidence":"Well-established for short-term use."},{"condition":"Tinea pedis (athlete's foot) with severe inflammation","description":"Provides antifungal action and relieves the itching and soreness caused by inflamed athlete's foot.","evidence":"Well-established for short-term use."}]
Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes used when both yeast overgrowth and inflammation are thought to contribute, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Erythrasma with secondary inflammation","description":"Rarely used when a bacterial infection is accompanied by significant inflammation, but this is not a recommended primary treatment.","evidence":"Limited"}]
Primary treatment for: Inflamed fungal skin infections such as tinea corporis, tinea cruris, and candidal intertrigo.
Also treats: Tinea pedis with inflammation, Seborrheic dermatitis with fungal component (off-label), Erythrasma with inflammation (off-label)
📋 Drug Information
| Generic Name(s) | Ketoconazole (2% w/w) + Beclometasone (0.025% w/w) |
| Brand Name | Nizowal-BN Plus Cream |
| Manufacturer | Wallace Pharmaceuticals Pvt Ltd |
| Packaging / Form | tube of 15 gm Cream (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C. Keep the tube tightly closed when not in use. Protect from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the pack. Do not use after the expiry date printed on the tube. |
| WHO Guideline | Not established from the available information. Topical antifungal-steroid combinations are generally used for short courses when inflammation is prominent, but specific WHO recommendations for this exact combination are not available. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has not published a specific guideline for this exact combination. Follow your doctor's advice. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary actions. Ketoconazole blocks the synthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the enzyme lanosterol 14-alpha-demethylase. This damages the fungal membrane and stops the fungus from growing. Beclometasone dipropionate binds to glucocorticoid receptors inside skin cells and reduces the release of inflammatory chemicals, which calms redness, swelling, itching, and pain. Together, the antifungal clears the infection while the steroid controls the inflammatory response.
Mechanism Steps
💡 How to Take Nizowal-BN Plus Cream
Strength: Topical cream containing ketoconazole 2% w/w and beclometasone dipropionate 0.025% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected skin once or twice daily, or as directed by your doctor. Gently rub it in until it disappears. The duration of treatment depends on the condition and usually ranges from one to four weeks. Do not use it for longer than your doctor recommends. Dose must be individualized by a qualified clinician based on the indication, the area of skin involved, and your response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine should not be used in children under 12 years unless a doctor specifically prescribes it, because children are more sensitive to the effects of corticosteroids. |
| Elderly Dosage | Older adults can use this medicine at the same strength as younger adults, but they should use it for the shortest possible time and on the smallest area needed. Elderly people are more likely to have thin skin and other medical conditions, so they should be monitored for skin thinning and other steroid side effects. |
| Renal Impairment | No specific dose adjustment is usually needed for topical use in people with kidney disease. However, tell your doctor if you have kidney problems, because any medicine absorbed into the bloodstream could affect kidney function. |
| Hepatic Impairment | No specific dose adjustment is usually needed for topical use in people with liver disease. However, if you have severe liver disease, use this cream with caution and only under medical supervision, because beclometasone is metabolised in the liver. |
| Maximum Daily Dose | The maximum daily dose depends on the size of the area being treated and the duration of use. Do not apply more than the prescribed amount. For adults, the usual maximum is a thin layer applied once or twice daily to the affected area. Long-term use over large areas should be avoided unless your doctor specifically recommends it. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Nizowal-BN Plus Cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Insulin | Major | |
| Oral corticosteroids | Major | |
| Ketoconazole tablets | Moderate | |
| Itraconazole | Moderate | |
| Clarithromycin | Moderate | |
| Ritonavir | Moderate | |
| Rifampicin | Moderate | |
| Carbamazepine | Moderate | |
| Furosemide | Moderate |
🚨 Major Interactions
- Oral anticoagulants such as warfarin
- Oral antidiabetic medicines and insulin
- Other corticosteroids (oral, inhaled, or topical)
⚡ Moderate Interactions
- CYP3A4 inhibitors such as ketoconazole tablets, itraconazole, clarithromycin, and ritonavir
- CYP3A4 inducers such as rifampicin, carbamazepine, and phenytoin
- Diuretics such as furosemide and thiazides
🍷 Alcohol Interaction
Alcohol does not directly interact with this topical cream. However, if you have a skin condition that is made worse by alcohol, or if you are also taking other medicines, alcohol may affect your overall health. It is best to drink alcohol only in moderation and to follow your doctor's advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ketoconazole, beclometasone, or any other ingredient in the cream","Untreated bacterial, viral, or tuberculous skin infections","Acne, rosacea, or perioral dermatitis","Use on the face, groin, or underarms for more than a few days without medical advice","Use in children under 12 years unless prescribed by a doctor","Use on large areas or with occlusive dressings for long periods without medical supervision"]
⚠️ Warnings & Precautions
["Do not use this cream for more than the recommended duration. Prolonged use can cause skin thinning, stretch marks, and increased absorption of the steroid.","Avoid contact with the eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.","Do not use this cream on the face unless your doctor specifically tells you to, because the skin there is more sensitive to steroids.","If you have diabetes, monitor your blood sugar more often, as the steroid can raise glucose levels.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not cover the treated area with airtight dressings unless your doctor instructs you to.","If the infection does not improve or gets worse, stop using the cream and consult your doctor.","Keep the cream out of reach of children."]
🤱 Lactation Safety
It is not known whether enough ketoconazole or beclometasone is absorbed from this cream to pass into breast milk in significant amounts. To be safe, do not apply the cream to the breasts or nipple area before breastfeeding. If you need to use it on the breast, wash the area thoroughly before feeding. Consult your doctor or a lactation specialist.
💊 Overdose Management
This medicine is for external use only. If you accidentally swallow the cream, rinse your mouth with water and contact a doctor or poison control centre immediately. If you apply too much cream, wipe off the excess and wash the area with water. Do not try to make yourself vomit. Signs of overdose from topical use are unlikely, but long-term overuse can lead to steroid side effects. Seek medical advice if you are concerned.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine exactly as prescribed by your doctor. Wash your hands before and after applying the cream. Clean and dry the affected skin gently before each application. Apply a thin layer and rub it in lightly; do not cover the area with airtight dressings unless your doctor tells you to. Avoid contact with the eyes, mouth, and other mucous membranes. Do not use this cream on the face, groin, or underarms for more than a few days without medical advice, because the steroid can be absorbed more easily from these areas. Do not use it for more than the recommended duration; longer use increases the risk of skin thinning and other steroid-related effects. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before using this medicine. Keep the cream out of reach of children. Do not share this medicine with others, even if they have similar symptoms. If the condition does not improve within the expected time or gets worse, contact your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults should use this medicine for the shortest possible time and on the smallest area needed. Elderly skin is often thinner and more sensitive to steroids, so the risk of skin thinning and other side effects is higher. Monitor for signs of skin changes and report them to your doctor. If you have diabetes or other medical conditions, your doctor may want to monitor you more closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, tell your doctor before using this medicine. Topical ketoconazole and beclometasone should be used during pregnancy only when clearly needed. Use the smallest amount for the shortest time and avoid large areas or occlusive dressings. Your doctor will help you weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently had surgery, tell your doctor before using this cream on or near the surgical area. Do not apply it to healing wounds unless your surgeon specifically advises it. The steroid can slow wound healing and increase the risk of infection.
🦷 Dental Procedures
This medicine is applied to the skin and does not usually affect dental procedures. However, if you are using it near the mouth or on the face, tell your dentist. There are no specific precautions for dental work with this topical cream.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can usually continue your normal exercise routine while using this medicine. However, if you have a fungal infection in the groin or feet, avoid activities that cause excessive sweating or friction until the infection clears. Shower and dry the area thoroughly after exercise. Wear clean, dry socks and shoes if you have athlete's foot.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and does not usually affect your ability to work or drive. If the cream makes your skin greasy, wait a few minutes before dressing or using equipment. If you have a fungal infection on your hands, avoid touching shared equipment until the infection clears. Follow good hand hygiene to prevent spreading the infection to others.
🛑 When to Stop This Medicine
Stop using this medicine when your doctor tells you to, or when the prescribed course is complete. Do not stop early, as the infection may return. If you notice skin thinning, stretch marks, or other side effects, stop the cream and consult your doctor. Do not use it for longer than recommended without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine can cause thinning of the skin, stretch marks, and changes in skin colour. The steroid can be absorbed into the bloodstream, especially when used over large areas or with occlusive dressings, leading to side effects such as high blood sugar, fluid retention, and adrenal suppression. To avoid these problems, use the cream only for the recommended duration and on the smallest area needed. Your doctor may monitor you for skin changes and other side effects if you need to use it for a longer time.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild fungal infections without much inflammation, a plain antifungal cream may be enough.
Evidence: Well-establishedGood hygiene and moisture control help prevent and treat fungal skin infections.
Evidence: Well-establishedFor widespread or stubborn infections, a doctor may prescribe oral antifungal treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine is applied to the skin and does not usually affect vaccinations. However, if you have a skin infection, tell your doctor before getting any vaccine. There are no specific vaccine timing considerations for this topical cream.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not freeze the cream.
✅ DO
Keep the tube tightly closed when not in use.
❌ DON'T
Do not leave the cap off for long periods.
✅ DO
Protect the cream from direct sunlight and moisture.
❌ DON'T
Do not store it in the bathroom cabinet where it may get damp.
✅ DO
Keep the cream out of reach of children.
❌ DON'T
Do not transfer the cream to another container.
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from direct sunlight and extreme heat. If you are travelling across time zones, continue applying the cream at your usual times; topical medicines do not usually need time-zone adjustment. Keep it in your hand luggage if you need it during the journey. Check the customs rules of your destination for prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Itching and redness often start to improve within a few days. The fungal infection usually begins to clear within one to two weeks. Complete the full course prescribed by your doctor.
A: Do not use this cream on your face unless your doctor specifically tells you to. The skin on the face is more sensitive to steroids and can thin more easily.
A: If you remember soon after the missed time, apply it then. If it is almost time for your next dose, skip the missed one. Do not apply a double dose.
A: Follow your doctor's advice. Stopping too early can allow the fungal infection to return. Complete the full course as prescribed.
A: Use it only if your doctor recommends it. Use the smallest amount for the shortest time and avoid large areas or occlusive dressings.
🤔 Common Patient Concerns
🔄 Substitutes for Nizowal-BN Plus Cream
View AllAlternative brands with exact same active ingredient:
-
dikart-bn creamCure Tech Skincare ₹73.13 12.4% CHEAPER
-
salisia b creamAjanta Pharma Ltd ₹74.06 11.2% CHEAPER
-
allyzole-b creamMDC Pharmaceuticals Pvt Ltd ₹75.00 10.1% CHEAPER
-
knozole-b creamBest Biotech ₹85.00 1.9% COSTLIER
-
kenozole-bg creamBrinton Pharmaceuticals Pvt Ltd ₹88.00 5.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This medicine is only for fungal skin infections with inflammation. It can make other skin conditions worse. - Myth: More cream means faster healing.
Fact: Applying more cream does not speed up healing and can increase the risk of side effects. Use only a thin layer as prescribed. - Myth: It is safe to use this cream for months.
Fact: Prolonged use can thin the skin, cause stretch marks, and increase steroid absorption. Use it only for the recommended duration. - Myth: This cream is safe for babies and young children.
Fact: It should not be used in children under 12 years unless a doctor prescribes it, because children are more sensitive to steroids.
🔄 Alternative Options
Generic Alternatives
- Ketoconazole 2% + Beclometasone 0.025% cream (generic)
Brand Alternatives
- Dikart-BN Cream