adaple-c gel
What is adaple-c gel used for?
This medicine contains Adapalene (0.1% w/w) + Clindamycin (1% w/w) and is used to treat DERMA. Adapalene binds to retinoic acid receptors (RARs) to normalize follicular keratinization; Clindamyci. Always consult your doctor before use.
- Generic Name: Adapalene + Clindamycin
- Manufacturer: Wallace Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Category C
- Prescription Required: Yes
💊 adaple-c gel Uses & Benefits
Acne vulgaris (inflammatory and non-inflammatory lesions)
Off-label uses: Keratosis pilaris, Photodamage, Melasma
📋 Drug Information
| Generic Name(s) | Adapalene + Clindamycin |
| Brand Name | Acnesol A Nano Gel |
| Manufacturer | Wallace Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoid + Antibiotic |
| Route of Administration | Topical |
| Storage | Store at 20-25°C (68-77°F); protect from light and heat |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Adapalene binds to retinoic acid receptors (RARs) to normalize follicular keratinization; Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Mechanism Steps
💡 How to Take adaple-c gel
Follow your doctor's prescription exactly.
⚠️ Side Effects of adaple-c gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Erythromycin | Major | Antagonism of clindamycin antibacterial effect |
| Tetracyclines | Major | Increased risk of pseudomembranous colitis |
| Systemic retinoids | Major | Increased risk of hypervitaminosis A |
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade |
| Topical corticosteroids | Moderate | May reduce efficacy of adapalene |
| Topical benzoyl peroxide | Moderate | May cause skin irritation; use with caution |
| Other topical antibiotics | Moderate | Possible cross-resistance or irritation |
🚨 Major Interactions
- Erythromycin
- Tetracyclines
- Systemic retinoids
- Neuromuscular blocking agents
⚡ Moderate Interactions
- Topical corticosteroids
- Topical benzoyl peroxide
- Other topical antibiotics
🍷 Alcohol Interaction
No known interaction
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to adapalene, clindamycin, or any component; history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis
🤱 Lactation Safety
Caution; not recommended during breastfeeding
💊 Overdose Management
Excessive topical application may cause severe irritation; treat symptomatically; accidental ingestion may cause gastrointestinal effects; supportive care
⏰ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose; do not double dose
🔄 Substitutes for adaple-c gel
View AllAlternative brands with exact same active ingredient:
-
alight gelLeeford Healthcare Ltd ₹45.00 86.7% CHEAPER
-
adclin gelSigman Wellness ₹65.00 80.7% CHEAPER
-
clearbet plus gelZeelab Pharmacy Pvt Ltd ₹75.00 77.8% CHEAPER
-
zathrin gelFDC Ltd ₹82.50 75.6% CHEAPER
-
clovin-a gelShinto Organics (P) Limited ₹84.38 75% CHEAPER
Medical Note: Always consult your doctor before switching medications.