adaple 0.1% gel - Uses, Price, Side Effects & Substitutes
What is adaple 0.1% gel used for?
Adaferin Gel (Adapalene) is used to treat DERMA. It contains Adapalene (0.1% w/w), which Binds to retinoic acid receptors (RARs), modulating gene expression to normalize. Always consult your doctor before use. Take as prescribed.
- Generic Name: Adapalene
- Manufacturer: Wallace Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ adaple 0.1% gel Uses & Benefits
Acne vulgaris (comedonal, inflammatory, and mixed acne).
Off-label uses: Photoaging, Keratosis pilaris, Melasma
๐ Drug Information
| Generic Name(s) | Adapalene |
| Brand Name | Adaferin Gel |
| Manufacturer | Wallace Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- Third generation |
| Route of Administration | Topical |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and heat. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to retinoic acid receptors (RARs), modulating gene expression to normalize follicular keratinization and reduce inflammation.
Mechanism Steps
๐ก How to Take adaple 0.1% gel
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adaple 0.1% gel
โ Common Side Effects
- Skin dryness
- Erythema
- Peeling
- Burning sensation
- Pruritus
๐จ Serious Side Effects
- Severe allergic reaction
- Angioedema
- Stevens-Johnson syndrome (rare)
โ ๏ธ Rare Side Effects
- Hyperpigmentation
- Hypopigmentation
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Other topical retinoids | Major | Increased risk of skin irritation and toxicity |
| Benzoyl peroxide | Major | Increased skin irritation; use at different times of day |
| Topical corticosteroids | Moderate | May reduce efficacy of adapalene |
| Topical antibiotics | Moderate | Possible additive irritation |
| Sunscreens | Minor | No significant interaction; use as directed |
| Cosmetics with drying agents | Minor | May increase skin dryness |
๐จ Major Interactions
- Other topical retinoids
- Benzoyl peroxide (concomitant use may cause irritation)
โก Moderate Interactions
- Topical corticosteroids
- Topical antibiotics (e.g., clindamycin)
โน๏ธ Minor Interactions
- Sunscreens
- Cosmetics with drying agents
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction; however, alcohol may increase skin dryness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to adapalene or any component; pregnancy (category C); eczema; sunburn.
๐ Monitoring Parameters
Skin irritation, dryness, peeling; therapeutic response (reduction in acne lesions).
๐คฑ Lactation Safety
Not recommended; unknown if excreted in breast milk.
๐ Overdose Management
Topical overdose unlikely; if ingested, treat symptomatically.
โฐ Missed Dose
Apply as soon as remembered; if close to next dose, skip missed dose. Do not double.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for adaple 0.1% gel
View AllAlternative brands with exact same active ingredient (Adapalene (0.1% w/w)):
-
acnerem gelZeelab Pharmacy Pvt Ltd โน30.00 60% CHEAPER
-
acreva ms 0.1% creamZee Laboratories โน62.81 16.3% CHEAPER
-
alene gelCadila Pharmaceuticals Ltd โน70.23 6.4% CHEAPER
-
difra gelSaga Laboratories โน70.31 6.3% CHEAPER
-
adina 0.1% gelCanbro Healthcare โน74.06 1.3% CHEAPER
-
alangel 0.1% creamSystopic Laboratories Pvt Ltd โน79.00 5.3% COSTLIER
-
vandep 0.1% gelDr. Johns Laboratories Pvt Ltd โน81.76 9% COSTLIER
-
daplin ointmentOrganic Laboratories โน83.34 11.1% COSTLIER
-
admark gelUnimarck Healthcare Ltd โน84.38 12.5% COSTLIER
-
adsure gelAssure Lifescience Pvt Ltd โน84.38 12.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.