Femic-p Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is mafnagesic tablet used for?
This medicine is a combination of mefenamic acid and paracetamol used for short-term relief of mild to moderate pain, including menstrual cramps, dental pain, and headache, and to reduce fever. It works by blocking pain-causing chemicals in the body.
- Generic Name: Mefenamic Acid (250mg) + Paracetamol (500mg)
- Manufacturer: Wockhardt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 mafnagesic tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेफेनामिक एसिड और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह मासिक धर्म के दर्द, दांत दर्द, सिरदर्द, मांसपेशियों के दर्द और जोड़ों के दर्द में राहत देती है। यह शरीर में दर्द पैदा करने वाले रसायनों को रोककर काम करती है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, त्वचा या आंखों का पीलापन, या चेहरे, होंठ या गले में सूजन दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक या लंबे समय तक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। चक्कर आने या नींद आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 mafnagesic tablet Uses & Benefits
[{"condition":"Menstrual cramps (Dysmenorrhea)","description":"Relieves moderate to severe pain associated with menstruation by reducing prostaglandin levels.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides short-term relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Headache","description":"Helps alleviate tension headaches and mild migraines.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Reduces pain and inflammation in conditions such as sprains, strains, and arthritis.","evidence":"Well-established"},{"condition":"Fever","description":"Lowers elevated body temperature due to the paracetamol component.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Postoperative pain","description":"Sometimes used for short-term pain relief after minor surgeries.","evidence":"Limited"},{"condition":"Migraine","description":"May be used to relieve acute migraine attacks, though not first-line.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Dysmenorrhea, Dental pain, Headache, Musculoskeletal pain, Fever
📋 Drug Information
| Generic Name(s) | Mefenamic Acid (250mg) + Paracetamol (500mg) |
| Brand Name | mafnagesic tablet |
| Manufacturer | Wockhardt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Mefenamic Acid is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins and thromboxanes, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, though its exact mechanism is not fully understood. Together, they provide analgesic, antipyretic, and anti-inflammatory effects.
Mechanism Steps
💡 How to Take mafnagesic tablet
Strength: Immediate-release tablet containing Mefenamic Acid 250 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 6 to 8 hours as needed for pain or fever, not to exceed 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not take for more than 7 days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose is 3 tablets (750 mg mefenamic acid and 1500 mg paracetamol) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of mafnagesic tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Alcohol | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., aspirin, ibuprofen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- SSRIs
- Alcohol
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen liver toxicity, especially with paracetamol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to mefenamic acid, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active or history of peptic ulcer or gastrointestinal bleeding.","Severe renal impairment.","Severe hepatic impairment.","Third trimester of pregnancy.","Children under 14 years of age (unless directed by a doctor)."]
⚠️ Warnings & Precautions
["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration of use.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with kidney or liver disease.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than 7 days for pain unless directed by a doctor.","Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Mefenamic acid and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose can cause severe nausea, vomiting, abdominal pain, drowsiness, and potentially liver or kidney damage. Seek immediate medical attention. Treatment is supportive and symptomatic. For paracetamol overdose, acetylcysteine may be administered as an antidote. For mefenamic acid overdose, management includes activated charcoal if within 2 hours of ingestion, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not use this medicine if you have a history of stomach ulcers, severe kidney or liver disease, or asthma triggered by NSAIDs. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor renal and hepatic function closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like mefenamic acid may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for postoperative pain relief, but it can increase the risk of bleeding. Consult your surgeon before taking it after surgery.
🦷 Dental Procedures
This medicine can be used for pain relief after dental procedures. Inform your dentist if you are taking it, as it may increase bleeding risk during dental surgery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that could cause injury while taking this medicine, as it may mask pain and lead to overexertion. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal daily activities if you feel well.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain or fever persists beyond 7 days, if you experience any serious side effects, or if you develop new symptoms. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and liver damage. It may also increase cardiovascular risk. Regular monitoring of kidney and liver function is advised if prolonged use is necessary. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedApplying heat or cold packs can help relieve localized pain and inflammation.
Evidence: Well-establishedStress reduction and relaxation can help manage chronic pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it as prescribed; no adjustment is needed for as-needed use. Check local customs regulations regarding prescription medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as this can increase the risk of side effects.
A: This medicine is for short-term use only. Do not take it for more than 7 days for pain without medical advice.
🤔 Common Patient Concerns
🔄 Substitutes for mafnagesic tablet
View AllAlternative brands with exact same active ingredient:
-
lenagesic 250mg/500mg tabletWockhardt Ltd ₹20.40 13.1% CHEAPER
-
mepar 250mg/500mg tabletEast West Pharma ₹26.25 11.8% COSTLIER
-
starpace-mf 250mg/500mg tabletMinova Life Sciences Pvt Ltd ₹26.44 12.7% COSTLIER
-
femic-p tabletDesta Lifescience ₹27.19 15.9% COSTLIER
-
mefex plus tabletMedicraft Group ₹28.13 19.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take for any type of pain without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. It is not suitable for all types of pain and can cause serious side effects if misused. - Myth: Taking this medicine with alcohol is safe.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver damage when taken with this medicine. It should be avoided. - Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use can increase the risk of kidney, liver, and gastrointestinal problems.
🔄 Alternative Options
Generic Alternatives
- Mefenamic Acid + Paracetamol tablet
Brand Alternatives
- Femic-P Tablet