Dolostan Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is meflup 250mg tablet used for?
This medicine contains Mefenamic Acid 250mg, an NSAID used for short-term relief of mild to moderate pain, inflammation, and fever. It works by blocking prostaglandins. Take it with food to reduce stomach upset and avoid alcohol.
- Generic Name: Mefenamic Acid (250mg)
- Manufacturer: Lupin Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 meflup 250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेफेनैमिक एसिड 250 मिलीग्राम युक्त एक दर्द निवारक और सूजन कम करने वाली दवा है। इसका उपयोग मासिक धर्म के दर्द, दांत दर्द, सिरदर्द, मांसपेशियों के दर्द, जोड़ों के दर्द और बुखार को कम करने के लिए किया जाता है। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायनों को रोककर काम करती है जो दर्द और सूजन का कारण बनते हैं। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सीने में जलन, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति और एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब में कमी, आंखों या त्वचा का पीलापन, या चेहरे और गले में सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक या अवधि से अधिक न लें। इसे हमेशा भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको पेट के अल्सर, गुर्दे या यकृत की बीमारी, उच्च रक्तचाप या हृदय की समस्या है तो अपने डॉक्टर को बताएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 meflup 250mg tablet Uses & Benefits
[{"condition":"Menstrual cramps (Dysmenorrhea)","description":"Relieves moderate to severe pain associated with menstruation by reducing prostaglandin levels.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from mild to moderate dental pain following procedures or due to infection.","evidence":"Well-established"},{"condition":"Headache","description":"Effective for tension headaches and mild migraines.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Reduces pain and inflammation in conditions like muscle strains, sprains, and arthritis.","evidence":"Well-established"},{"condition":"Fever","description":"Helps lower fever by acting on the hypothalamus.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used for short-term pain management after minor surgeries.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"Occasionally prescribed to prevent migraines, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Menstrual cramps, Dental pain, Headache, Musculoskeletal pain, Fever
📋 Drug Information
| Generic Name(s) | Mefenamic Acid (250mg) |
| Brand Name | meflup 250mg tablet |
| Manufacturer | Lupin Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (fenamates) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the cyclooxygenase enzymes, specifically COX-1 and COX-2, which are involved in the production of prostaglandins. Prostaglandins are chemicals that cause pain, inflammation, and fever. By blocking these enzymes, this medicine reduces the levels of prostaglandins, thereby alleviating pain and inflammation. It also has antipyretic effects by acting on the hypothalamus to reduce fever.
Mechanism Steps
💡 How to Take meflup 250mg tablet
Strength: Tablet, 250 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg to 500 mg taken two to three times daily, depending on the severity of pain and the condition being treated. The maximum recommended daily dose is 1500 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take with food or milk to reduce stomach upset. Do not exceed the prescribed dose or duration. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | 1500 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of meflup 250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Lithium
- Methotrexate
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Beta-blockers
- SSRIs
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding and can worsen side effects such as dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Mefenamic Acid or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Heart failure","Third trimester of pregnancy","Children under 14 years of age","History of asthma, urticaria, or allergic reactions to aspirin or other NSAIDs"]
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not use for more than 7 days without medical advice.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart disease.","Do not take other NSAIDs or pain relievers without consulting your doctor.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","If you are pregnant or breastfeeding, consult your doctor before use."]
🤱 Lactation Safety
This medicine is excreted in breast milk in small amounts. It is generally considered safe for short-term use during breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, stomach pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart problems. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but consult your surgeon before taking it, as it can increase bleeding risk and interact with other medications.
🦷 Dental Procedures
This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or drowsiness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. If you experience dizziness, rest and avoid driving or operating machinery.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe for office work, but take regular breaks if you have a desk job.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly if you are on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor if you need to take it for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain management.
Evidence: Well-establishedApplying heat or cold packs can help relieve localized pain.
Evidence: Well-establishedStress reduction can help manage chronic pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Do not take other NSAIDs or pain relievers without consulting your doctor, as it may increase the risk of side effects.
A: Consult your doctor before taking this medicine during pregnancy, especially in the third trimester.
🤔 Common Patient Concerns
🔄 Substitutes for meflup 250mg tablet
View AllAlternative brands with exact same active ingredient:
-
mf 250mg capsulePan Pharmaceuticals Ltd ₹5.47 1.7% COSTLIER
-
StayHappi Mefenamic Acid 250mg TabletSarvagunaushdhi Pvt Ltd ₹11.46 113% COSTLIER
-
mifucet 250mg tabletIntas Pharmaceuticals Ltd ₹14.00 160.2% COSTLIER
-
almefkem 250 dt tabletAlkem Laboratories Ltd ₹17.62 227.5% COSTLIER
-
mefalgin 250mg tabletAnthus Pharmaceuticals Pvt Ltd ₹17.77 230.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset. - Myth: This medicine is safe for long-term use without monitoring.
Fact: Long-term use requires monitoring of kidney and liver function and may increase cardiovascular risk. - Myth: This medicine can be taken with other pain relievers.
Fact: Combining with other NSAIDs increases the risk of side effects and should be avoided unless directed by a doctor.
🔄 Alternative Options
Generic Alternatives
- Mefenamic Acid 250mg tablet
Brand Alternatives
- Dolostan 250mg Tablet
- Mefanorm 250mg Tablet
- Mefkind 250mg Tablet