femic-p tablet - Mefenamic Acid (250mg) + Paracetamol (500mg) medicine

Femic-p Tablet: Comprehensive Medicine Guide

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🏭 Desta Lifescience 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 30, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like mefenamic acid are generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus. Paracetamol is considered relatively safe during pregnancy when used as directed. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term pain relief.
Reviewed by
SaathiMed Expert Panel | Oct 30, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is femic-p tablet used for?

This medicine is a combination of mefenamic acid and paracetamol used for short-term relief of mild to moderate pain, including menstrual cramps, dental pain, and headache, and to reduce fever. It works by blocking pain-causing chemicals in the body.

  • Generic Name: Mefenamic Acid (250mg) + Paracetamol (500mg)
  • Manufacturer: Desta Lifescience
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 femic-p tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मेफेनामिक एसिड और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह मासिक धर्म के दर्द, दांत दर्द, सिरदर्द, मांसपेशियों के दर्द और जोड़ों के दर्द में राहत देती है। यह शरीर में दर्द पैदा करने वाले रसायनों को रोककर काम करती है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, त्वचा या आंखों का पीलापन, या चेहरे, होंठ या गले में सूजन दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक या लंबे समय तक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। चक्कर आने या नींद आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 femic-p tablet Uses & Benefits

[{"condition":"Menstrual cramps (Dysmenorrhea)","description":"Relieves moderate to severe pain associated with menstruation by reducing prostaglandin levels.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides short-term relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Headache","description":"Helps alleviate tension headaches and mild migraines.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Reduces pain and inflammation in conditions such as sprains, strains, and arthritis.","evidence":"Well-established"},{"condition":"Fever","description":"Lowers elevated body temperature due to the paracetamol component.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Postoperative pain","description":"Sometimes used for short-term pain relief after minor surgeries.","evidence":"Limited"},{"condition":"Migraine","description":"May be used to relieve acute migraine attacks, though not first-line.","evidence":"Limited"}]

Primary treatment for: Pain and inflammation

Also treats: Dysmenorrhea, Dental pain, Headache, Musculoskeletal pain, Fever

📋 Drug Information

Generic Name(s)Mefenamic Acid (250mg) + Paracetamol (500mg)
Brand Namefemic-p tablet
ManufacturerDesta Lifescience
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach irritation.
2
Do not exceed the recommended dose of 3 tablets in 24 hours.
3
Avoid alcohol completely while taking this medicine to prevent stomach bleeding.
4
If you have a history of ulcers or kidney disease, inform your doctor before taking this medicine.
5
Do not use this medicine for more than 7 days for pain without consulting your doctor.
6
Stay well hydrated throughout the day to support kidney function.
7
Report any unusual bleeding, bruising, or dark stools to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Menstrual cramps
This medicine is commonly prescribed for this.
Likely Use
✅
Dental pain
This medicine is commonly prescribed for this.
Likely Use
✅
Headache
This medicine can be used for tension headaches.
Likely Use
✅
Fever
This medicine contains paracetamol which reduces fever.
Likely Use
❌
Chest pain
This medicine is not for chest pain; seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMefenamic Acid is rapidly absorbed from the gastrointestinal tract after oral administration. Paracetamol is also well absorbed orally. Food may delay the onset of action but does not significantly reduce the extent of absorption.
DistributionMefenamic Acid is highly bound to plasma proteins and distributes into synovial fluid and other tissues. Paracetamol distributes widely into most body tissues, with a volume of distribution of approximately 0.9 L/kg.
Protein BindingMefenamic Acid is approximately 90% bound to plasma proteins. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismMefenamic Acid is metabolized in the liver primarily by CYP2C9 to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of Mefenamic Acid is approximately 2 hours. Paracetamol has a half-life of 2 to 3 hours.
ExcretionMefenamic Acid metabolites are excreted primarily in urine (about 50%) and feces. Paracetamol metabolites are excreted mainly in urine.
BioavailabilityMefenamic Acid oral bioavailability is approximately 90%. Paracetamol oral bioavailability is about 80-90%.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations of Mefenamic Acid occur about 2 hours after dosing. Paracetamol peaks within 0.5 to 2 hours.
Duration of ActionThe analgesic effect lasts approximately 4 to 6 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Mefenamic Acid is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins and thromboxanes, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, though its exact mechanism is not fully understood. Together, they provide analgesic, antipyretic, and anti-inflammatory effects.

Mechanism Steps

1
Inhibition of cyclooxygenase: Mefenamic Acid binds to and reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This inhibition decreases the production of prostaglandins, which are key mediators of pain, inflammation, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain perception, contributing to analgesia and fever reduction.
4
Combined effect: The combined actions result in enhanced pain relief and fever reduction compared to either agent alone.

💡 How to Take femic-p tablet

Strength: Immediate-release tablet containing Mefenamic Acid 250 mg and Paracetamol 500 mg.

1Take this medicine orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Do not lie down immediately after taking.
5Follow the prescribed dose and duration exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 6 to 8 hours as needed for pain or fever, not to exceed 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not take for more than 7 days without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseMaximum daily dose is 3 tablets (750 mg mefenamic acid and 1500 mg paracetamol) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or milk
Reduces stomach upset and gastrointestinal irritation.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of femic-p tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and take with food. Consult doctor if severe or persistent.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. If pain is severe, seek medical advice.
Heartburn (Common (5-10%))
Take with food and avoid lying down immediately after taking. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. If severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid driving or operating machinery. Consult doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report severe stomach pain or indigestion to your doctor immediately.
Kidney problems (Rare (<0.1%))
Seek medical attention if you experience decreased urination, swelling, or fatigue.
Liver damage (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, difficulty breathing, or severe rash.
Blood disorders (Rare (<0.1%))
Report unusual bleeding, bruising, or signs of infection to your doctor.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, fever, and sensitivity to light.
Stevens-Johnson syndrome
Seek emergency care if you develop a painful rash with blisters, peeling skin, or sores in the mouth.
Toxic epidermal necrolysis
Seek emergency care if you experience widespread skin peeling, blisters, or sores.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
SSRIs Moderate
Alcohol Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., aspirin, ibuprofen)
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • SSRIs
  • Alcohol

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen liver toxicity, especially with paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to mefenamic acid, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active or history of peptic ulcer or gastrointestinal bleeding.","Severe renal impairment.","Severe hepatic impairment.","Third trimester of pregnancy.","Children under 14 years of age (unless directed by a doctor)."]

⚠️ Warnings & Precautions

["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration of use.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with kidney or liver disease.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than 7 days for pain unless directed by a doctor.","Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Mefenamic acid and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose can cause severe nausea, vomiting, abdominal pain, drowsiness, and potentially liver or kidney damage. Seek immediate medical attention. Treatment is supportive and symptomatic. For paracetamol overdose, acetylcysteine may be administered as an antidote. For mefenamic acid overdose, management includes activated charcoal if within 2 hours of ingestion, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not use this medicine if you have a history of stomach ulcers, severe kidney or liver disease, or asthma triggered by NSAIDs. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor renal and hepatic function closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like mefenamic acid may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.

🏥 Post-Surgery Considerations

This medicine may be used for postoperative pain relief, but it can increase the risk of bleeding. Consult your surgeon before taking it after surgery.

🦷 Dental Procedures

This medicine can be used for pain relief after dental procedures. Inform your dentist if you are taking it, as it may increase bleeding risk during dental surgery.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and muscles.
🥗
Engage in regular low-impact exercise such as walking or swimming.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Stay well hydrated throughout the day.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that could cause injury while taking this medicine, as it may mask pain and lead to overexertion. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include omega-3 rich foods such as fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables.
Stay well hydrated by drinking plenty of water.
Limit caffeine and alcohol intake.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal daily activities if you feel well.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever persists beyond 7 days, if you experience any serious side effects, or if you develop new symptoms. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney problems, and liver damage. It may also increase cardiovascular risk. Regular monitoring of kidney and liver function is advised if prolonged use is necessary. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Heat or cold therapy

Applying heat or cold packs can help relieve localized pain and inflammation.

Evidence: Well-established
Relaxation techniques

Stress reduction and relaxation can help manage chronic pain.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it as prescribed; no adjustment is needed for as-needed use. Check local customs regulations regarding prescription medicines before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 28-year-old woman with severe menstrual cramps
She was prescribed this medicine for dysmenorrhea. She took one tablet with food at the onset of cramps and experienced significant relief within an hour. She noted that taking it with food prevented the nausea she had experienced with other painkillers.
💡 Lesson: Taking this medicine with food improves tolerability and provides effective relief for menstrual cramps.
👤 A 45-year-old man with dental pain
After a tooth extraction, he was prescribed this medicine for pain. He took it as directed every 8 hours and found that his pain was well controlled. He avoided alcohol and did not exceed the recommended dose.
💡 Lesson: Adhering to the prescribed dose and avoiding alcohol ensures safe and effective pain relief.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as this can increase the risk of side effects.

Q: How long can I take this medicine?

A: This medicine is for short-term use only. Do not take it for more than 7 days for pain without medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for femic-p tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take for any type of pain without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision. It is not suitable for all types of pain and can cause serious side effects if misused.
  • Myth: Taking this medicine with alcohol is safe.
    Fact: Alcohol increases the risk of gastrointestinal bleeding and liver damage when taken with this medicine. It should be avoided.
  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is intended for short-term use only. Long-term use can increase the risk of kidney, liver, and gastrointestinal problems.

🔄 Alternative Options

Generic Alternatives

  • Mefenamic Acid + Paracetamol tablet

Brand Alternatives

  • Femic-P Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Mefenamic Acid + Paracetamol","composition":"Mefenamic Acid 250 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Good for menstrual cramps and dental pain."},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen 400 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Similar uses; may have different side effect profile."}]

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