lomostop d 50 mg/200 mg/10 mg tablet - Furazolidone (50mg) + Metronidazole (200mg) medicine

Genogyl F 50 Mg/200 Mg Tablet: Complete Medicine Guide

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🏭 Wings Biotech Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Avoid in the first trimester and near term. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited to moderate for specific indications.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Seizures or loss of consciousness
  • Numbness or tingling in hands or feet

If experiencing severe symptoms, call emergency services immediately.

What is lomostop d 50 mg/200 mg/10 mg tablet used for?

This medicine is a combination of furazolidone and metronidazole used to treat certain intestinal infections caused by bacteria and protozoa. It works by killing the microorganisms. It should be taken with food and alcohol must be avoided.

  • Generic Name: Furazolidone (50mg) + Metronidazole (200mg)
  • Manufacturer: Wings Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lomostop d 50 mg/200 mg/10 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा फ्यूराज़ोलिडोन और मेट्रोनिडाज़ोल का संयोजन है, जिसका उपयोग आंतों के कुछ संक्रमणों जैसे जियार्डिया और बैक्टीरियल एंटराइटिस के इलाज के लिए किया जाता है। यह संक्रमण पैदा करने वाले कीटाणुओं को मारती है। इसे भोजन के साथ लेना चाहिए और शराब से पूरी तरह बचना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द और मुँह में धातु जैसा स्वाद शामिल हैं। कभी-कभी पेशाब का रंग गहरा पीला या भूरा हो सकता है, जो हानिरहित है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें हाथ-पैरों में झुनझुनी, दौरे, रक्त विकार और एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। शराब के साथ लेने पर गंभीर प्रतिक्रिया हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। उपचार के दौरान और आखिरी खुराक के 48 घंटे बाद तक शराब न लें। यदि आपको लीवर या किडनी की बीमारी है, या पहले कभी दौरे पड़े हैं, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर रखें। खुराक छूट जाने पर अगली खुराक दोगुनी न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 lomostop d 50 mg/200 mg/10 mg tablet Uses & Benefits

[{"condition":"Giardiasis","description":"This medicine is used to treat intestinal infection caused by Giardia lamblia, a protozoan parasite that causes diarrhea and malabsorption.","evidence":"Well-established"},{"condition":"Bacterial enteritis","description":"It may be prescribed for certain bacterial diarrheas caused by susceptible organisms, though resistance patterns vary.","evidence":"Limited"},{"condition":"Amebiasis","description":"Metronidazole component is effective against Entamoeba histolytica, but combination use is not standard first-line.","evidence":"Limited"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Metronidazole is part of some regimens, but this specific combination is not standard.","evidence":"Limited"}]

Primary treatment for: Giardiasis

Also treats: Bacterial enteritis, Amebiasis

📋 Drug Information

Generic Name(s)Furazolidone (50mg) + Metronidazole (200mg)
Brand Namelomostop d 50 mg/200 mg/10 mg tablet
ManufacturerWings Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture, unless otherwise specified on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol completely during treatment and for 48 hours after the last dose.
3
Complete the full course even if you feel better to prevent relapse.
4
Report any numbness, tingling, or weakness in hands or feet immediately.
5
Stay well hydrated, especially if you have diarrhea.
6
Do not use this medicine for viral diarrhea or non-infectious causes.
7
Inform your doctor if you have liver or kidney disease before starting this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic diarrhea
This medicine is commonly prescribed for specific infectious diarrheas.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Abdominal cramps
May be prescribed if caused by susceptible organisms.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFurazolidone is poorly absorbed from the gastrointestinal tract, with most of the drug remaining in the gut lumen. Metronidazole is well absorbed orally, reaching peak plasma concentrations within 1 to 2 hours. Food may delay absorption of metronidazole slightly but does not significantly affect overall bioavailability.
DistributionMetronidazole distributes widely into body tissues and fluids, including cerebrospinal fluid, saliva, and breast milk. Furazolidone remains largely in the gastrointestinal tract due to poor absorption. Protein binding of metronidazole is low (less than 20%).
Protein BindingMetronidazole is less than 20% bound to plasma proteins. Furazolidone protein binding is not well established.
MetabolismMetronidazole is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9 and CYP3A4, to hydroxy and acid metabolites. Furazolidone is partially metabolized in the gut and liver, but detailed pathways are not fully characterized.
Half-LifeThe elimination half-life of metronidazole is approximately 6 to 8 hours in adults with normal renal and hepatic function. Furazolidone half-life is not well established.
ExcretionMetronidazole and its metabolites are excreted primarily in urine (about 60-80% of a dose), with a smaller fraction in feces. Furazolidone is mainly excreted in feces due to poor absorption.
BioavailabilityMetronidazole oral bioavailability is high, approximately 80-100%. Furazolidone bioavailability is low due to poor absorption.
Onset of ActionSymptom improvement may begin within 24 to 48 hours of starting therapy, but complete eradication requires completing the full course.
Peak Plasma TimeMetronidazole peak plasma concentration occurs 1 to 2 hours after oral administration. Furazolidone peak is not well established.
Duration of ActionThe antimicrobial effect persists as long as therapeutic concentrations are maintained. Metronidazole is usually dosed 2 to 3 times daily to maintain levels.

How It Works

This medicine combines two antimicrobial agents with different mechanisms. Furazolidone is reduced by bacterial and protozoal enzymes to reactive intermediates that damage DNA and other macromolecules, inhibiting growth. Metronidazole enters susceptible organisms and is reduced by ferredoxin-like electron transport proteins, creating reactive radicals that cause DNA strand breakage and cell death. The combination targets a broad range of anaerobic bacteria and protozoa.

Mechanism Steps

1
Furazolidone activation: Furazolidone is taken up by susceptible microorganisms and reduced by nitroreductases to reactive intermediates.
2
DNA damage by furazolidone: These intermediates bind to DNA and proteins, disrupting replication and causing cell death.
3
Metronidazole uptake: Metronidazole diffuses into anaerobic organisms and is reduced by ferredoxin-like proteins.
4
Radical formation: Reduced metronidazole forms nitro radical anions that cause DNA strand breaks.
5
Microbial death: The combined damage leads to inhibition of nucleic acid synthesis and cell death.

💡 How to Take lomostop d 50 mg/200 mg/10 mg tablet

Strength: Tablet containing furazolidone 50 mg and metronidazole 200 mg.

1Take this medicine orally with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Avoid alcohol completely during and for 48 hours after treatment.
6Complete the full course even if you feel better.
7Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally 2 to 3 times daily, depending on the infection being treated. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of infection, age, weight, renal and hepatic function. Do not self-medicate. Always complete the full course as prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more susceptible to side effects such as peripheral neuropathy and blood disorders. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for individualized dosing.
Renal ImpairmentMetronidazole dose may need adjustment in patients with severe renal impairment. Furazolidone is poorly absorbed, so renal adjustment may not be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Metronidazole is metabolized in the liver, and dose reduction may be required. Furazolidone should be avoided in severe liver disease. Consult a doctor for individualized dosing.
Maximum Daily DoseNot established from the available information. The maximum daily dose must be determined by a qualified clinician based on the specific indication and patient factors.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Tyramine-rich foods (aged cheese, cured meats)
Avoid
Furazolidone has MAOI activity and may cause hypertensive crisis.
Alcohol
Avoid completely
Can cause disulfiram-like reaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of lomostop d 50 mg/200 mg/10 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum or rinsing mouth may help.
Dark urine (Common (5-10%))
This is harmless and resolves after stopping the medicine. Stay hydrated.
Headache (Common (5-10%))
Rest and stay hydrated. If severe or persistent, contact your doctor.
Abdominal discomfort (Common (5-10%))
Take with meals. Avoid spicy foods. Consult if pain worsens.

🚨 Serious Side Effects

Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning in hands or feet immediately. May require stopping the medicine.
Seizures (Rare (<0.1%))
Seek emergency medical attention if seizures occur.
Blood dyscrasias (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection. Blood tests may be needed.
Severe allergic reaction (Rare (<0.1%))
Seek immediate help if you experience rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Disulfiram-like reaction with alcohol
Avoid alcohol completely. Seek emergency care if flushing, vomiting, or chest pain occurs.
Hepatitis
Report yellowing of eyes or skin, dark urine, or right upper abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Lithium Major
Phenytoin Moderate
Cimetidine Moderate
Cyclosporine Moderate
Antacids Minor

🚨 Major Interactions

  • Alcohol
  • Warfarin
  • Lithium
  • Phenytoin

⚡ Moderate Interactions

  • Cimetidine
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol must be strictly avoided during treatment with this medicine and for at least 48 hours after the last dose. Combining them can cause a disulfiram-like reaction with symptoms such as severe nausea, vomiting, flushing, headache, rapid heartbeat, and low blood pressure. In severe cases, it can be life-threatening.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to furazolidone, metronidazole, or other nitroimidazoles/nitrofurans","Pregnancy (especially first trimester and near term)","Breastfeeding","Severe liver disease","Severe kidney disease","Use of alcohol or disulfiram within the past 2 weeks","Children under 1 month of age"]

⚠️ Warnings & Precautions

["Avoid alcohol during and for 48 hours after treatment.","May cause peripheral neuropathy with prolonged use; report numbness or tingling.","May cause dark urine, which is harmless.","Use with caution in patients with blood dyscrasias or seizures.","May interact with tyramine-rich foods due to MAOI activity of furazolidone.","Do not use for viral infections or non-bacterial diarrhea.","Complete the full course as prescribed to prevent resistance."]

🤱 Lactation Safety

Metronidazole is excreted in breast milk and may affect the nursing infant. Furazolidone may also pass into breast milk. Consult your doctor before breastfeeding while taking this medicine. Pumping and discarding milk may be advised during treatment.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, headache, dizziness, and possibly seizures or peripheral neuropathy. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and neurological status.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others. Avoid all alcohol-containing products during treatment and for at least 48 hours after the last dose, as this can cause a severe reaction. Inform your doctor if you have liver disease, kidney disease, or a history of blood disorders or seizures. Do not use this medicine for longer than recommended without medical supervision. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose. Seek immediate medical help if you experience signs of an allergic reaction, severe dizziness, or irregular heartbeat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to peripheral neuropathy and blood disorders. Use with caution and monitor closely. Dose adjustment may be needed based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

This medicine should be avoided during pregnancy, especially in the first trimester and near term. If you are planning pregnancy, consult your doctor before taking this medicine. Use effective contraception during treatment.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery. It is not routinely used post-surgery unless there is a specific infection.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain medications used during dental procedures. Avoid alcohol-containing mouthwashes.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hand hygiene to prevent reinfection.
🥗
Drink plenty of fluids to stay hydrated, especially during diarrhea.
😴
Avoid alcohol and tyramine-rich foods during treatment.
💧
Eat a balanced diet to support recovery.
🧘
Get adequate rest to help your body fight infection.
🌞
Follow food safety practices to prevent intestinal infections.

🏋️ Exercise Considerations

If you experience dizziness, fatigue, or weakness while taking this medicine, avoid strenuous exercise or operating heavy machinery until you feel better. Stay hydrated during exercise.

🥗 Diet Recommendations

Stay well hydrated with water and oral rehydration solutions.
Eat bland, easy-to-digest foods like rice, bananas, and toast.
Avoid spicy, oily, and processed foods.
Avoid alcohol and tyramine-rich foods.
Include probiotics like yogurt if tolerated, but separate from medicine by 2 hours.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you feel unwell. Take sick leave if needed until symptoms improve. Follow good hygiene to prevent spreading infection to colleagues.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early can lead to relapse and resistance. If you experience serious side effects, contact your doctor immediately; they may advise stopping the medicine.

📅 Long-Term Use Effects

Prolonged use of this medicine may increase the risk of peripheral neuropathy, blood disorders, and liver toxicity. Regular monitoring of blood counts and liver function may be advised for long-term therapy. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral rehydration therapy

Essential for managing dehydration from diarrhea.

Evidence: Well-established
Probiotics

May help restore gut flora, but should be taken separately from antibiotics.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccination timing if you are due for any vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Avoid alcohol during travel. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with persistent diarrhea and bloating
He was diagnosed with giardiasis and prescribed this medicine. He took it with food as directed and avoided alcohol. His symptoms improved within 3 days, and he completed the 7-day course. He reported mild nausea initially, which subsided.
💡 Lesson: Taking the medicine with food and completing the full course led to successful treatment.
👤 A 50-year-old woman with bacterial enteritis
She was prescribed this medicine for a bacterial intestinal infection. She experienced a metallic taste and dark urine, which her doctor reassured were harmless. She completed the course and recovered fully.
💡 Lesson: Minor side effects like metallic taste and dark urine are common and harmless; do not stop the medicine without consulting your doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Symptom improvement may begin within 24 to 48 hours, but you must complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember unless it is almost time for the next dose. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for lomostop d 50 mg/200 mg/10 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of diarrhea.
    Fact: It is only effective against specific bacterial and protozoal infections. It does not treat viral or non-infectious diarrhea.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent relapse and resistance.

🔄 Alternative Options

Generic Alternatives

  • Furazolidone + Metronidazole combination generics

Brand Alternatives

  • Genogyl F 50 mg/200 mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Furazolidone 50 mg + Metronidazole 200 mg","uses":"Giardiasis, bacterial enteritis","notes":"Combination product"},{"medicine":"Metronidazole alone","composition":"Metronidazole","uses":"Anaerobic infections, giardiasis, amebiasis","notes":"Single agent"}]

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