Diastop Mf Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing
- Severe headache with a very high blood pressure reading
- Blood in stool or vomit
- Severe abdominal pain that does not go away
- Yellowing of the skin or eyes
- Numbness, tingling, or burning in the hands or feet
- Unusual bruising or bleeding
- Confusion, drowsiness, or difficulty speaking
- Seizures
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is diastop mf tablet used for?
This medicine is a combination of furazolidone and metronidazole used to treat certain intestinal infections caused by susceptible bacteria and protozoa. It is a prescription medicine and must be taken exactly as directed, with food, and with strict avoidance of alcohol and tyramine-rich foods.
- Generic Name: Furazolidone + Metronidazole
- Manufacturer: Apple Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 diastop mf tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्यूराज़ोलिडोन और मेट्रोनिडाज़ोल का संयोजन है, जिसका उपयोग कुछ आंतों के संक्रमणों के इलाज के लिए किया जाता है। यह उन बैक्टीरिया और प्रोटोज़ोआ को मारती है जो दस्त, पेट दर्द, गैस और अपच जैसी समस्याएँ पैदा करते हैं। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए। इसे भोजन के साथ लें और पूरा कोर्स पूरा करें। इस दवा के साथ शराब बिल्कुल न लें और पनीर, अचार, सोया सॉस जैसे खाद्य पदार्थों से बचें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, भूख न लगना, मुँह में धातु जैसा स्वाद, सिरदर्द और पेशाब का रंग गहरा होना शामिल है। कुछ लोगों को चक्कर आना, थकान या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, साँस लेने में कठिनाई, हाथ-पैर में झुनझुनी, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और भोजन के साथ लें ताकि पेट खराब न हो। इलाज के दौरान और आखिरी खुराक के कम से कम तीन दिन बाद तक शराब न लें। पनीर, प्रोसेस्ड मीट, सोया सॉस, खमीर वाले खाद्य पदार्थ और ब्रॉड बीन से बचें। अगर चक्कर आए तो गाड़ी न चलाएँ। पूरा कोर्स पूरा करें, बीच में दवा न छोड़ें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं।
💊 diastop mf tablet Uses & Benefits
[{"condition":"Giardiasis","description":"Used to treat intestinal infection caused by Giardia lamblia, which leads to prolonged diarrhea, bloating, and greasy stools.","evidence":"Established for metronidazole; furazolidone has also been used for giardiasis."},{"condition":"Bacterial enteritis","description":"May be used for certain bacterial diarrheal infections when susceptibility is known or suspected by the clinician.","evidence":"Limited and depends on local resistance patterns."},{"condition":"Intestinal amoebiasis","description":"Metronidazole is effective against Entamoeba histolytica, and combination therapy may be used in some settings.","evidence":"Established for metronidazole."},{"condition":"Trichomoniasis","description":"Metronidazole is a standard treatment for this sexually transmitted protozoal infection.","evidence":"Established for metronidazole."},{"condition":"Bacterial vaginosis","description":"Metronidazole is commonly used to treat this condition, though combination with furazolidone is not standard.","evidence":"Established for metronidazole."}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Metronidazole is sometimes part of combination regimens for H. pylori, but this specific combination is not a standard regimen.","evidence":"Limited for this combination."},{"condition":"Rosacea","description":"Metronidazole has anti-inflammatory uses in rosacea, but oral use of this combination is not established.","evidence":"Limited and not for this product."}]
Primary treatment for: Intestinal infections caused by susceptible protozoa and bacteria, such as giardiasis and certain bacterial enteritis.
Also treats: Amoebiasis, Trichomoniasis, Bacterial vaginosis
📋 Drug Information
| Generic Name(s) | Furazolidone + Metronidazole |
| Brand Name | Aristogyl-F Oral Suspension |
| Manufacturer | Apple Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibacterial, Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place. Keep the tablets in the original container, tightly closed, away from direct sunlight, heat, and moisture. Do not store in the bathroom. |
| Shelf Life | Not established from the available information. Check the expiry date printed on the pack and do not use after that date. |
| WHO Guideline | Not established from the available information. This specific combination is not a standard WHO-recommended regimen for diarrheal illness. |
| ICMR Guideline | Not established from the available information. Clinicians should follow current national and local guidelines for the treatment of specific infections. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Furazolidone enters susceptible microorganisms and is reduced by bacterial enzymes to reactive intermediates that damage DNA, proteins, and other cellular components, leading to microbial death. Metronidazole is a prodrug that is activated inside anaerobic organisms and protozoa by reductive processes; the resulting reactive metabolites cause DNA strand breakage and inhibit nucleic acid synthesis. The combination targets susceptible bacteria and protozoa in the intestinal tract, helping to stop their growth and spread. Furazolidone also has mild monoamine oxidase inhibitor activity, which explains some of its food and drug interactions.
Mechanism Steps
💡 How to Take diastop mf tablet
Strength: Each tablet contains furazolidone 50 mg and metronidazole 200 mg in an immediate-release oral dosage form.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times daily, but the exact dose and duration depend on the infection being treated, its severity, and the patient's kidney and liver function. Some infections require a longer course, while others may need a different regimen. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Always complete the full course prescribed by your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children unless specifically prescribed by a specialist. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, confusion, and blood pressure changes. Kidney and liver function should be assessed before use, and the dose may need to be adjusted. Use with caution and monitor closely. |
| Renal Impairment | In patients with severe kidney impairment, metronidazole clearance may be reduced, and dose adjustment may be needed. Furazolidone's kidney-related dosing is not established. Consult your doctor for individualized dosing if you have kidney disease. |
| Hepatic Impairment | In patients with severe liver disease, this medicine is contraindicated. In milder liver impairment, dose reduction or avoidance may be advised because both components are metabolized in the liver. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | Not established from the available information. The maximum daily dose must be determined by a qualified clinician based on the specific infection and patient factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of diastop mf tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| MAOIs | Major | |
| Lithium | Major | |
| Cimetidine | Moderate | |
| Phenytoin | Moderate | |
| Phenobarbital | Moderate | |
| Fluorouracil | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Alcohol
- Warfarin
- Monoamine oxidase inhibitors (MAOIs)
- Tyramine-rich foods
- Lithium
⚡ Moderate Interactions
- Cimetidine
- Phenytoin
- Phenobarbital
- Fluorouracil
- Cyclosporine
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least three days after the last dose. Combining alcohol with metronidazole can cause a disulfiram-like reaction with severe nausea, vomiting, flushing, headache, and a rapid heartbeat. Furazolidone also has monoamine oxidase inhibitor activity, and alcohol can worsen this interaction. If you accidentally consume alcohol, seek medical advice if you develop severe symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to furazolidone, metronidazole, or other nitroimidazoles or nitrofurans","Severe liver disease","Alcohol consumption during treatment and for at least three days after","Use with monoamine oxidase inhibitors","First trimester of pregnancy unless absolutely necessary","Breastfeeding without specialist advice","Use in children under the age recommended by a pediatrician"]
⚠️ Warnings & Precautions
["Do not consume alcohol during treatment and for at least three days after the last dose.","Avoid tyramine-rich foods such as aged cheese, cured meats, fermented soy products, and broad bean pods.","Do not drive or operate machinery if you feel dizzy or sleepy.","Inform your doctor about all other medicines, especially blood thinners, antidepressants, and blood pressure medicines.","Complete the full course as prescribed, even if you feel better.","Do not use this medicine for ordinary diarrhea without medical advice.","Report numbness, tingling, or burning in the hands or feet immediately.","Use with caution in people with liver or kidney disease.","Keep out of reach of children.","Do not share this medicine with others."]
🤱 Lactation Safety
Metronidazole passes into breast milk and may affect the nursing infant. Furazolidone safety during breastfeeding is not established. This medicine is generally not recommended during breastfeeding. If treatment is essential, your doctor may advise temporarily stopping breastfeeding or pumping and discarding milk for a period after each dose.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, dizziness, headache, and potentially serious blood pressure changes or neurological symptoms. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include stomach emptying if the overdose was recent, monitoring of vital signs, blood tests, and management of specific symptoms. Do not try to treat an overdose at home.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if less than half the dosing interval has passed. If more than half the interval has passed, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, with food to reduce stomach upset. Do not drink alcohol while taking this medicine and for at least three days after the last dose, because a serious reaction with severe vomiting, flushing, headache, and rapid heartbeat can occur. Avoid aged cheese, cured meats, fermented foods, soy sauce, broad bean pods, and other tyramine-rich foods during treatment, as furazolidone can interact with them and raise blood pressure. Do not drive or operate heavy machinery if you feel dizzy or sleepy. Complete the full course even if you feel better after a few days, because stopping early can allow the infection to return. Inform your doctor about all other medicines, especially blood thinners, antidepressants, and blood pressure medicines. Do not use this medicine for ordinary loose motions without medical advice. Keep it out of reach of children and store it in the original container away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience dizziness, confusion, and blood pressure changes with this medicine. Kidney and liver function should be checked before starting treatment, and the dose may need adjustment. Monitor closely for signs of dehydration and neurological symptoms.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before starting it. This medicine is generally not recommended during pregnancy, especially in the first trimester. Your doctor may choose a safer alternative based on your condition.
🏥 Post-Surgery Considerations
Not established from the available information. If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. They will assess whether it is safe to continue.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific contraindications, but your dentist may want to coordinate with your doctor, especially if you are taking other medicines or have liver or kidney problems.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you are unwell with an intestinal infection, as dehydration and fatigue can worsen your condition. Light activity such as walking is fine if you feel up to it. Do not exercise if you feel dizzy, weak, or have a fever. Rehydrate well before and after any physical activity.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tiredness, or headache, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. If your work involves physical labor, take frequent breaks and stay hydrated. Inform your employer if you need to take time off to recover from the infection.
🛑 When to Stop This Medicine
Stop this medicine only after completing the full prescribed course, or earlier if your doctor advises you to stop because of side effects or another reason. Do not stop on your own just because you feel better. If you experience serious side effects such as severe allergic reactions, neurological symptoms, or signs of liver injury, stop the medicine and seek medical attention immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically advised by a specialist. Prolonged use can increase the risk of peripheral neuropathy, blood-related side effects, and liver toxicity. If long-term treatment is necessary, your doctor may monitor your blood counts, liver function, and neurological symptoms regularly. Do not continue this medicine beyond the prescribed duration without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Replacing lost fluids and electrolytes is essential for managing diarrhea and preventing dehydration.
Evidence: Well-establishedZinc can reduce the duration and severity of diarrhea in some patients, especially children.
Evidence: Well-established in childrenCertain probiotic strains may help restore gut flora and reduce diarrhea duration.
Evidence: ModerateDepending on the identified organism, a different targeted medicine may be more appropriate.
Evidence: Well-established for specific infections💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known vaccine interactions specific to this medicine. If you are due for a vaccine, inform your doctor that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container, tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you in case customs or security asks for it. Store the tablets in a cool, dry place away from direct sunlight and moisture. If you are crossing time zones, ask your doctor how to adjust the dosing schedule. Do not pack this medicine in checked luggage if you need it during the flight. Avoid alcohol and tyramine-rich foods throughout your trip while taking this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within one to three days, but you must complete the full prescribed course to clear the infection completely.
A: No. Stopping early can allow the infection to return and may lead to resistance. Complete the full course as prescribed.
A: Avoid alcohol completely and avoid tyramine-rich foods such as aged cheese, cured meats, fermented soy products, and broad bean pods.
A: Pediatric dosing is not established from available information. Consult a pediatrician before giving this medicine to a child.
A: This medicine is generally not recommended during pregnancy, especially in the first trimester. Consult your doctor for safer alternatives.
🤔 Common Patient Concerns
🔄 Substitutes for diastop mf tablet
View AllAlternative brands with exact same active ingredient:
-
genogyl f 50 mg/200 mg tabletGeno Pharmaceuticals Ltd ₹4.61 72.1% CHEAPER
-
lomostop d 50 mg/200 mg/10 mg tabletWings Biotech Ltd ₹6.02 63.5% CHEAPER
-
Fumedil CapsuleJohnson & Johnson Ltd ₹17.84 8.1% COSTLIER
-
religyl f tabletMedico Healthcare ₹18.00 9.1% COSTLIER
-
mfd care 50mg/200mg/10mg tabletBiochem Pharmaceutical Industries ₹22.40 35.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of diarrhea.
Fact: This medicine is only for specific infections caused by susceptible organisms. It is not effective for viral diarrhea or simple food-related upset stomach. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full prescribed course to prevent the infection from returning and to reduce the risk of resistance. - Myth: Drinking a little alcohol is safe with this medicine.
Fact: Even a small amount of alcohol can cause a severe reaction. Avoid alcohol completely during treatment and for at least three days after. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription medicine. Self-medication can be unsafe and may delay correct treatment.
🔄 Alternative Options
Generic Alternatives
- Furazolidone 50 mg + Metronidazole 200 mg tablet (generic)