Alcorim F 800mg/160mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Rash, blisters, or peeling skin, especially with fever or mouth sores.
- Severe or bloody diarrhoea.
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain.
- Unusual bruising or bleeding, or a sore throat with fever.
- Decreased urine output or swelling in the legs.
- Severe headache with neck stiffness or sensitivity to light.
- Difficulty breathing or swelling of the face, lips, or throat.
- Chest pain or irregular heartbeat.
If experiencing severe symptoms, call emergency services immediately.
What is jolltrim-ds tablet used for?
This medicine is a combination antibiotic containing sulfamethoxazole 800 mg and trimethoprim 160 mg. It is used to treat bacterial infections such as urinary tract infections, respiratory infections, and Pneumocystis jirovecii pneumonia. It works by blocking two steps in bacterial folate synthesis. It is a prescription medicine and should be taken exactly as directed by a doctor.
- Generic Name: Sulfamethoxazole (800mg) + Trimethoprim (160mg)
- Manufacturer: Jolly Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 jolltrim-ds tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सल्फामेथोक्साज़ोल और ट्राइमेथोप्रिम का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और निमोनिया के इलाज में प्रभावी है। यह दवा बैक्टीरिया के फोलेट संश्लेषण को रोककर उन्हें मारती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, भूख न लगना, सिरदर्द और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में त्वचा की गंभीर प्रतिक्रियाएं, रक्त विकार, यकृत की क्षति और गुर्दे की समस्या शामिल हो सकती है। यदि आपको दाने, बुखार, मुंह में छाले, असामान्य रक्तस्राव या पेशाब में कमी दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें। इसे भरपूर पानी के साथ लें। दिन में पर्याप्त पानी पिएं। धूप में ज्यादा देर न रहें क्योंकि यह दवा त्वचा को सूरज की रोशनी के प्रति संवेदनशील बना सकती है। यदि आपको सल्फा दवाओं से एलर्जी है तो यह दवा न लें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। इस दवा को किसी और के साथ साझा न करें।
💊 jolltrim-ds tablet Uses & Benefits
[{"condition":"Uncomplicated urinary tract infection","description":"This medicine is commonly prescribed for acute uncomplicated cystitis caused by susceptible organisms such as Escherichia coli.","evidence":"Well-established"},{"condition":"Acute exacerbation of chronic bronchitis","description":"Used when bacterial infection is confirmed or strongly suspected and the organism is susceptible.","evidence":"Well-established"},{"condition":"Pneumocystis jirovecii pneumonia","description":"This medicine is a first-line treatment and prophylaxis option for Pneumocystis jirovecii pneumonia in immunocompromised patients.","evidence":"Well-established"},{"condition":"Traveler's diarrhoea","description":"Used for moderate to severe traveler's diarrhoea caused by susceptible bacteria when treatment is indicated.","evidence":"Moderate"},{"condition":"Skin and soft tissue infections","description":"Prescribed for infections such as cellulitis and impetigo when caused by susceptible organisms.","evidence":"Moderate"},{"condition":"Nocardiosis","description":"Used as part of therapy for Nocardia infections in selected patients.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prophylaxis in neutropenic patients","description":"Sometimes used to prevent bacterial infections in patients with prolonged neutropenia, though local resistance patterns must be considered.","evidence":"Limited"},{"condition":"Stenotrophomonas maltophilia infection","description":"Occasionally used in combination regimens for this resistant organism when no better options exist.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infection, Chronic bronchitis exacerbation, Pneumocystis jirovecii pneumonia, Traveler's diarrhoea, Skin and soft tissue infections, Nocardiosis
📋 Drug Information
| Generic Name(s) | Sulfamethoxazole (800mg) + Trimethoprim (160mg) |
| Brand Name | jolltrim-ds tablet |
| Manufacturer | Jolly Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place. Keep it in the original container, tightly closed, and protect it from direct sunlight and moisture. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer. Always check the expiry date on the pack before use. |
| WHO Guideline | Not established from the available information. The World Health Organization includes sulfamethoxazole-trimethoprim in its Model List of Essential Medicines for the treatment and prophylaxis of Pneumocystis jirovecii pneumonia and for certain other infections. Always follow local guidelines and your doctor's advice. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research publishes treatment guidelines for various infections, and this medicine may be included in some of them. Consult your doctor for guidance specific to your condition. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by sequentially blocking two enzymes in the bacterial folate synthesis pathway. Sulfamethoxazole inhibits dihydropteroate synthase, which prevents the formation of dihydrofolic acid from para-aminobenzoic acid. Trimethoprim inhibits dihydrofolate reductase, which prevents the conversion of dihydrofolic acid to tetrahydrofolic acid. Because tetrahydrofolic acid is required for the synthesis of thymidine and purines, blocking both steps together stops bacterial DNA and RNA production. This sequential blockade is synergistic and is usually bactericidal against susceptible organisms, whereas each component alone is generally bacteriostatic.
Mechanism Steps
💡 How to Take jolltrim-ds tablet
Strength: Each tablet contains sulfamethoxazole 800 mg and trimethoprim 160 mg in an immediate-release formulation.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for most uncomplicated infections is one tablet (800 mg sulfamethoxazole and 160 mg trimethoprim) taken orally twice daily, approximately every 12 hours. For Pneumocystis jirovecii pneumonia, higher doses are used under specialist supervision. The duration of treatment depends on the type and severity of the infection and usually ranges from 3 to 14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific tablet strength. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially if they have reduced kidney function. The dose may need to be adjusted based on renal function. Close monitoring for side effects is recommended. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine may need to be reduced. For creatinine clearance between 15 and 30 mL/min, the dose is usually halved. For creatinine clearance below 15 mL/min, this medicine is generally not recommended unless the benefits outweigh the risks and under specialist supervision. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no specific dose adjustment is usually required, but caution is advised. In severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is usually two tablets (1600 mg sulfamethoxazole and 320 mg trimethoprim) per day for standard indications. Higher doses may be used for Pneumocystis jirovecii pneumonia under specialist supervision. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of jolltrim-ds tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Phenytoin | Major | |
| ACE inhibitors | Major | |
| Potassium-sparing diuretics | Major | |
| Amiodarone | Moderate | |
| Dofetilide | Moderate | |
| Repaglinide | Moderate | |
| Rifampicin | Moderate | |
| Ciclosporin | Moderate |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Phenytoin
- ACE inhibitors and angiotensin receptor blockers
- Potassium-sparing diuretics
⚡ Moderate Interactions
- Amiodarone
- Dofetilide
- Repaglinide
- Pioglitazone
- Rifampicin
- Ciclosporin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both alcohol and this medicine can stress the liver, and combining them may increase the risk of liver injury. Alcohol can also worsen nausea, vomiting, and dizziness. If you drink alcohol regularly, discuss this with your doctor before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to sulfonamides or trimethoprim","Infants less than two months of age","Pregnancy at term or during breastfeeding of infants with jaundice or G6PD deficiency","Severe hepatic impairment","Severe renal impairment without specialist supervision","Megaloblastic anaemia due to folate deficiency","Concurrent use with dofetilide"]
⚠️ Warnings & Precautions
["Serious skin reactions such as Stevens-Johnson syndrome can occur. Stop the medicine and seek immediate care if a rash appears.","Blood dyscrasias including agranulocytosis and aplastic anaemia have been reported. Monitor blood counts during prolonged therapy.","This medicine can cause acute liver injury. Monitor liver function in at-risk patients.","Acute kidney injury and crystalluria can occur. Maintain adequate hydration.","Hyperkalaemia may occur, especially in patients with renal impairment or those taking ACE inhibitors or potassium-sparing diuretics.","This medicine can cause photosensitivity. Avoid prolonged sun exposure and use sunscreen.","Patients with glucose-6-phosphate dehydrogenase deficiency are at risk of haemolysis.","This medicine may increase the risk of hypoglycaemia in patients taking antidiabetic drugs.","Do not use this medicine for viral infections such as the common cold or flu.","Complete the full course as prescribed to prevent resistance."]
🤱 Lactation Safety
This medicine is excreted in breast milk. It should be used with caution in breastfeeding mothers, especially if the infant is premature, jaundiced, or has glucose-6-phosphate dehydrogenase deficiency. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, dizziness, headache, and mental depression. In severe cases, bone marrow suppression and liver toxicity may occur. Treatment is supportive and symptomatic. Gastric lavage may be considered if the patient presents early. Monitor blood counts, liver function, and renal function. Folinic acid may be considered in cases of significant bone marrow suppression. Contact a poison control centre or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed and complete the full course even if you feel better after a few days. Swallow the tablet whole with a full glass of water to reduce the risk of kidney crystal formation. Drink plenty of fluids throughout the day while taking this medicine. Avoid prolonged exposure to sunlight because this medicine can make your skin more sensitive to UV rays. Do not take this medicine if you are allergic to sulfa drugs or trimethoprim. Tell your doctor about all other medicines you take, especially blood thinners, diabetes medicines, and diuretics. Do not share this medicine with anyone else. Keep it out of reach of children. If you develop a rash, fever, mouth sores, or any sign of bleeding, stop the medicine and seek medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may be more sensitive to the side effects of this medicine. Dose adjustment may be necessary based on renal function. Close monitoring for blood disorders, kidney injury, and hyperkalaemia is recommended. Elderly patients should stay well hydrated and report any unusual symptoms promptly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. This medicine is generally avoided during the first trimester and near term because it can interfere with folate metabolism and increase the risk of birth defects and neonatal jaundice. Use effective contraception while taking this medicine and for a short period after.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. It may interact with other medicines used during surgery and can affect blood clotting and kidney function. Your doctor may advise you to stop this medicine before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can increase the risk of bleeding, especially if you are also taking blood thinners. Your dentist may need to take extra precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue in some patients. Avoid strenuous exercise or activities that require mental alertness until you know how this medicine affects you. If you feel dizzy or weak, rest and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, or confusion in some patients. Avoid driving or operating heavy machinery until you know how it affects you. If your work involves mental alertness, discuss with your doctor. Most people can continue their normal daily activities while taking this medicine, but rest is important for recovery.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the prescribed course, even if you feel better. Stopping early can lead to a return of the infection and antibiotic resistance. If you experience a serious side effect such as a severe rash, difficulty breathing, or yellowing of the eyes, stop the medicine and seek immediate medical attention. Always consult your doctor before stopping this medicine for any reason.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of blood disorders such as anaemia, leukopenia, and thrombocytopenia, as well as liver and kidney toxicity. Regular monitoring of blood counts, liver function, and kidney function is recommended for patients on prolonged therapy. Folate supplementation may be considered in some cases. If you are on long-term therapy, your doctor will periodically review the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water can help flush out bacteria in uncomplicated urinary tract infections.
Evidence: LimitedSome studies suggest cranberry products may help prevent urinary tract infections, but evidence is mixed.
Evidence: LimitedProbiotics may help prevent antibiotic-associated diarrhoea and restore gut flora.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine. There is no specific contraindication, but your doctor will advise based on your overall health.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or extreme temperatures. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to maintain approximately 12-hour intervals. Check the customs regulations of your destination country regarding prescription medicines. Carry enough supply for your entire trip and a few extra doses in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but you must complete the full course as prescribed.
A: Yes, taking it with food reduces stomach upset. Swallow it with a full glass of water.
A: If you remember within 6 hours, take the missed dose. If more than 6 hours have passed, skip it and continue with your regular schedule. Do not double dose.
A: It is best to avoid alcohol because it can increase the risk of liver toxicity and stomach upset.
A: This medicine should be used during pregnancy only if clearly needed. It is generally avoided in the first trimester and near term. Consult your doctor.
A: No, you must complete the full course as prescribed to prevent the infection from returning and to reduce the risk of antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for jolltrim-ds tablet
View AllAlternative brands with exact same active ingredient:
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supristol ds 800mg/160mg tabletZydus Cadila ₹8.94 76.8% CHEAPER
-
cortina ds 800mg/160mg tabletLupin Ltd ₹10.17 73.6% CHEAPER
-
antrima ds 800mg/160mg tabletAbbott ₹10.29 73.3% CHEAPER
-
osotrim ds 800mg/160mg tabletOsho Pharma Pvt Ltd ₹10.31 73.2% CHEAPER
-
Sepnil DS 800mg/160mg TabletTOSC International Pvt Ltd ₹10.31 73.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce the risk of antibiotic resistance. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for people with sulfa allergy, severe kidney or liver disease, or certain blood disorders. It should be used with caution in pregnancy and breastfeeding. - Myth: Taking this medicine with alcohol is fine.
Fact: Alcohol should be avoided while taking this medicine because it can increase the risk of liver toxicity and stomach upset.
🔄 Alternative Options
Generic Alternatives
- Sulfamethoxazole and trimethoprim 800 mg/160 mg tablet
Brand Alternatives
- Alcorim F 800mg/160mg tablet