Itopride 50 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Involuntary muscle movements, tremor, or rigidity
- Severe allergic reaction: rash, itching, swelling of face/lips/throat, difficulty breathing
- High fever with muscle rigidity and altered mental status
- Severe abdominal pain or blood in stool
- Signs of liver problems: yellowing of skin or eyes, dark urine
- Persistent vomiting or inability to keep fluids down
If experiencing severe symptoms, call emergency services immediately.
What is itoz 50mg tablet used for?
This medicine contains itopride 50 mg, a prokinetic agent used to treat functional dyspepsia. It works by blocking dopamine D2 receptors and inhibiting acetylcholinesterase, improving gastric emptying and reducing symptoms like fullness, early satiety, and upper abdominal pain. It is taken orally, usually three times a day before meals.
- Generic Name: Itopride (50mg)
- Manufacturer: Wallace Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 itoz 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा इटोप्राइड 50 मिलीग्राम टैबलेट है, जिसका उपयोग कार्यात्मक अपच (फंक्शनल डिस्पेप्सिया) के लक्षणों जैसे पेट के ऊपरी हिस्से में दर्द, भरा हुआ महसूस होना, जल्दी पेट भर जाना और पेट में जलन को कम करने के लिए किया जाता है। यह दवा पेट और आंतों की गति को बढ़ाकर भोजन को आगे बढ़ाने में मदद करती है। यह डोपामाइन D2 रिसेप्टर को ब्लॉक करती है और एसिटाइलकोलिनेस्टरेज़ को रोकती है, जिससे पाचन क्रिया में सुधार होता है। इसे आमतौर पर भोजन से पहले दिन में तीन बार लिया जाता है। इस दवा को डॉक्टर की सलाह के बिना न लें और न ही बंद करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट दर्द, दस्त, कब्ज, सिरदर्द और मुँह सूखना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी चक्कर आना, नींद में गड़बड़ी या दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको मांसपेशियों में अकड़न, कंपन या असामान्य हरकतें महसूस हों, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा न बढ़ाएँ या घटाएँ। टैबलेट को पानी के साथ पूरा निगलें, चबाएँ नहीं। इसे भोजन से पहले लें। इस दवा के साथ शराब न लें, क्योंकि इससे नींद और चक्कर आ सकते हैं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, वाहन न चलाएँ। बच्चों की पहुँच से दूर रखें।
💊 itoz 50mg tablet Uses & Benefits
[{"condition":"Functional dyspepsia","description":"Relieves upper abdominal discomfort, postprandial fullness, early satiety, and epigastric pain or burning.","evidence":"Well-established"},{"condition":"Gastroparesis","description":"May improve gastric emptying and reduce symptoms such as nausea, vomiting, and bloating in patients with delayed gastric emptying.","evidence":"Moderate"},{"condition":"Gastro-oesophageal reflux disease (GERD)","description":"Sometimes used as an adjunct to improve gastric motility and reduce reflux symptoms, though not a first-line treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"May be prescribed off-label to improve gastric emptying in diabetic patients with gastroparesis.","evidence":"Limited"},{"condition":"Functional vomiting","description":"Occasionally used off-label to reduce vomiting in patients with functional gastrointestinal disorders.","evidence":"Limited"}]
Primary treatment for: Functional dyspepsia
Also treats: Gastroparesis, Gastro-oesophageal reflux disease
📋 Drug Information
| Generic Name(s) | Itopride (50mg) |
| Brand Name | itoz 50mg tablet |
| Manufacturer | Wallace Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Dopamine (D2) receptor antagonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine exerts its prokinetic effects through a dual mechanism. It blocks dopamine D2 receptors in the gastrointestinal tract, which reduces the inhibitory effect of dopamine on gastric motility. Additionally, it inhibits acetylcholinesterase, the enzyme responsible for breaking down acetylcholine. This inhibition increases acetylcholine levels at the neuromuscular junction, enhancing cholinergic transmission and promoting coordinated gastric and intestinal contractions. Unlike some other prokinetic agents, itopride does not significantly affect gastric acid secretion or serum prolactin levels at therapeutic doses.
Mechanism Steps
💡 How to Take itoz 50mg tablet
Strength: 50 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 50 mg taken orally three times daily before meals. However, the dose may be adjusted by your doctor based on your condition, response to treatment, and renal or hepatic function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor. |
| Renal Impairment | In patients with renal impairment, dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | 150 mg per day in divided doses, unless otherwise directed by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of itoz 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Atropine | Major | |
| Haloperidol | Major | |
| Warfarin | Moderate | |
| Beta-blockers | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Anticholinergic drugs (e.g., atropine, hyoscine)
- Dopamine antagonists (e.g., haloperidol, metoclopramide)
⚡ Moderate Interactions
- Warfarin
- Beta-blockers
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to itopride or any component of the formulation","Gastrointestinal bleeding, mechanical obstruction, or perforation","Patients with known QT prolongation or receiving drugs that prolong QT"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal or hepatic impairment.","Avoid use in patients with a history of extrapyramidal symptoms.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for prolonged periods without medical supervision.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
It is not known whether itopride is excreted in human breast milk. Caution is advised when used during breastfeeding. Consult your doctor before use.
💊 Overdose Management
There is no specific antidote for itopride overdose. Treatment should be symptomatic and supportive. If overdose is suspected, contact a poison control centre or emergency room immediately. Gastric lavage may be considered if ingestion is recent.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it. It can be taken with or without food, but taking it with food may reduce the chance of stomach upset. Avoid alcohol while taking this medicine, as it may increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use it after the expiry date printed on the pack.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and extrapyramidal symptoms. Dose adjustment may be necessary based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to improve gastric motility, but only under medical supervision. Inform your surgeon and anaesthesiologist that you are taking this medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It is generally safe for dental procedures, but your dentist may take precautions if you have any underlying conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or drowsiness, avoid strenuous activities or exercise until you know how the medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your usual work activities, but take precautions if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise whether to stop or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine may require periodic monitoring of renal and hepatic function. There is limited information on the effects of prolonged use beyond several months. It is advisable to use the lowest effective dose for the shortest duration necessary. Regular follow-up with your doctor is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating smaller, low-fat meals can help reduce dyspepsia symptoms.
Evidence: Well-establishedTechniques like yoga, meditation, and deep breathing can improve functional dyspepsia.
Evidence: ModerateSome studies suggest acupuncture may help with functional dyspepsia symptoms.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Keep enough supply for your entire trip. Check local customs regulations regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose. However, full therapeutic benefits for functional dyspepsia may take a few days to weeks.
A: It may interact with certain drugs like anticholinergics, dopamine antagonists, and warfarin. Always inform your doctor about all medicines you are taking.
A: Long-term use should be under medical supervision. Your doctor may periodically review your condition and adjust the dose.
🤔 Common Patient Concerns
🔄 Substitutes for itoz 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
re tride 50mg tabletTorrent Pharmaceuticals Ltd ₹35.63 6.5% CHEAPER
-
discom 50mg tabletHetero Drugs Ltd ₹38.49 1% COSTLIER
-
zeto 50mg tabletAbbott ₹38.51 1% COSTLIER
-
itoflux 50mg tabletAristo Pharmaceuticals Pvt Ltd ₹39.09 2.5% COSTLIER
-
itonorm 50mg tabletGufic Bioscience Ltd ₹42.40 11.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller; it is a prokinetic agent that improves gut motility. - Myth: This medicine can be taken for any stomach problem.
Fact: It is specifically for functional dyspepsia and certain motility disorders; it is not for all stomach issues. - Myth: You can stop this medicine as soon as you feel better.
Fact: You should complete the prescribed course and consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Itopride 50 mg tablet
Brand Alternatives
- Ganaton
- Itopride
- Itopride 50 mg